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Packagede.medizininformatikinitiative.kerndatensatz.onkologie
Resource TypeBundle
Idvalidation-oo.json
FHIR VersionR4

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Narrative

No narrative content found in resource


Source1

{
  "resourceType": "Bundle",
  "type": "collection",
  "timestamp": "2026-09-15T07:03:17.880+00:00",
  "entry": [
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ImplementationGuide-mii-ig-onko-de",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ImplementationGuide-mii-ig-onko-de",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 3730
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ImplementationGuide|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ImplementationGuide/mii-ig-onko-de: ImplementationGuide.extension[4].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7122
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ImplementationGuide|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ImplementationGuide/mii-ig-onko-de: ImplementationGuide.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7364
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ImplementationGuide|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'http://fhir.org/packages/de.basisprofil.r4/ImplementationGuide/de.basisprofil.r4'"
            },
            "expression": [
              "ImplementationGuide/mii-ig-onko-de: ImplementationGuide.dependsOn[0].uri"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8730
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ImplementationGuide|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'http://fhir.org/packages/de.medizininformatikinitiative.kerndatensatz.laborbefund/ImplementationGuide/de.medizininformatikinitiative.kerndatensatz.laborbefund'"
            },
            "expression": [
              "ImplementationGuide/mii-ig-onko-de: ImplementationGuide.dependsOn[6].uri"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7415
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "IG_DEPENDENCY_INVALID_URL"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The canonical URL http://fhir.org/packages/de.basisprofil.r4/ImplementationGuide/de.basisprofil.r4 doesn't point to an actual ImplementationGuide resource"
            },
            "expression": [
              "ImplementationGuide/mii-ig-onko-de: ImplementationGuide.dependsOn[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8830
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "IG_DEPENDENCY_INVALID_URL"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The canonical URL http://fhir.org/packages/de.medizininformatikinitiative.kerndatensatz.laborbefund/ImplementationGuide/de.medizininformatikinitiative.kerndatensatz.laborbefund doesn't point to an actual ImplementationGuide resource"
            },
            "expression": [
              "ImplementationGuide/mii-ig-onko-de: ImplementationGuide.dependsOn[6]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/AdverseEvent-mii-exa-onko-nebenwirkung-anaemie-grad3",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "AdverseEvent-mii-exa-onko-nebenwirkung-anaemie-grad3",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-nebenwirkung-adverse-event|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.meddra.org' version 'null' could not be found, so the code cannot be validated. Valid versions: [3.0.0]"
            },
            "expression": [
              "AdverseEvent/mii-exa-onko-nebenwirkung-anaemie-grad3: AdverseEvent.event.coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-nebenwirkung-adverse-event|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "AdverseEvent/mii-exa-onko-nebenwirkung-anaemie-grad3: AdverseEvent.event.coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "NO_VALID_DISPLAY_FOUND_NONE_FOR_LANG_ERR"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-nebenwirkung-adverse-event|2027.0.0-ballot.1"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Wrong Display Name 'Anämie' for https://www.meddra.org#10002272. There are no valid display names found for language(s) 'en'. Default display is 'null'"
            },
            "expression": [
              "AdverseEvent/mii-exa-onko-nebenwirkung-anaemie-grad3: AdverseEvent.event.coding[0].display"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-nebenwirkung-adverse-event|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Wrong Display Name 'Anämie' for https://www.meddra.org#10002272. There are no valid display names found for language(s) 'en'. Default display is 'null'"
            },
            "expression": [
              "AdverseEvent/mii-exa-onko-nebenwirkung-anaemie-grad3: AdverseEvent.event.coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/AdverseEvent-mii-exa-onko-nebenwirkung-crs-grad4",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "AdverseEvent-mii-exa-onko-nebenwirkung-crs-grad4",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-nebenwirkung-adverse-event|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.meddra.org' version 'null' could not be found, so the code cannot be validated. Valid versions: [3.0.0]"
            },
            "expression": [
              "AdverseEvent/mii-exa-onko-nebenwirkung-crs-grad4: AdverseEvent.event.coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-nebenwirkung-adverse-event|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "AdverseEvent/mii-exa-onko-nebenwirkung-crs-grad4: AdverseEvent.event.coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "NO_VALID_DISPLAY_FOUND_NONE_FOR_LANG_ERR"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-nebenwirkung-adverse-event|2027.0.0-ballot.1"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Wrong Display Name 'Zytokin-Freisetzungs-Syndrom' for https://www.meddra.org#10052015. There are no valid display names found for language(s) 'en'. Default display is 'null'"
            },
            "expression": [
              "AdverseEvent/mii-exa-onko-nebenwirkung-crs-grad4: AdverseEvent.event.coding[0].display"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-nebenwirkung-adverse-event|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Wrong Display Name 'Zytokin-Freisetzungs-Syndrom' for https://www.meddra.org#10052015. There are no valid display names found for language(s) 'en'. Default display is 'null'"
            },
            "expression": [
              "AdverseEvent/mii-exa-onko-nebenwirkung-crs-grad4: AdverseEvent.event.coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/AdverseEvent-mii-exa-onko-nebenwirkung-rektale-mukositis-grad2",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "AdverseEvent-mii-exa-onko-nebenwirkung-rektale-mukositis-grad2",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "NO_VALID_DISPLAY_FOUND_NONE_FOR_LANG_ERR"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-nebenwirkung-adverse-event|2027.0.0-ballot.1"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Wrong Display Name 'Rektale Mukositis' for https://www.meddra.org#10063190. There are no valid display names found for language(s) 'en'. Default display is 'null'"
            },
            "expression": [
              "AdverseEvent/mii-exa-onko-nebenwirkung-rektale-mukositis-grad2: AdverseEvent.event.coding[0].display"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-nebenwirkung-adverse-event|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Wrong Display Name 'Rektale Mukositis' for https://www.meddra.org#10063190. There are no valid display names found for language(s) 'en'. Default display is 'null'"
            },
            "expression": [
              "AdverseEvent/mii-exa-onko-nebenwirkung-rektale-mukositis-grad2: AdverseEvent.event.coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/AdverseEvent-mii-exa-onko-oxaliplatin-neuropathy",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "AdverseEvent-mii-exa-onko-oxaliplatin-neuropathy",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 28
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "NO_VALID_DISPLAY_FOUND_NONE_FOR_LANG_ERR"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/AdverseEvent|4.0.1"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Wrong Display Name 'Peripheral sensory neuropathy' for https://www.meddra.org#10034620. There are no valid display names found for language(s) 'en'. Default display is 'null'"
            },
            "expression": [
              "AdverseEvent/mii-exa-onko-oxaliplatin-neuropathy: AdverseEvent.event.coding[0].display"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/AdverseEvent-mii-pr-onko-nebenwirkung-0",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "AdverseEvent-mii-pr-onko-nebenwirkung-0",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-nebenwirkung-adverse-event|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.meddra.org' version 'null' could not be found, so the code cannot be validated. Valid versions: [3.0.0]"
            },
            "expression": [
              "AdverseEvent/mii-pr-onko-nebenwirkung-0: AdverseEvent.event.coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-nebenwirkung-adverse-event|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "AdverseEvent/mii-pr-onko-nebenwirkung-0: AdverseEvent.event.coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "NO_VALID_DISPLAY_FOUND_NONE_FOR_LANG_ERR"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-nebenwirkung-adverse-event|2027.0.0-ballot.1"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Wrong Display Name 'Fatigue' for https://www.meddra.org#10016256. There are no valid display names found for language(s) 'en'. Default display is 'null'"
            },
            "expression": [
              "AdverseEvent/mii-pr-onko-nebenwirkung-0: AdverseEvent.event.coding[0].display"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-nebenwirkung-adverse-event|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Wrong Display Name 'Fatigue' for https://www.meddra.org#10016256. There are no valid display names found for language(s) 'en'. Default display is 'null'"
            },
            "expression": [
              "AdverseEvent/mii-pr-onko-nebenwirkung-0: AdverseEvent.event.coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/AdverseEvent-mii-pr-onko-nebenwirkung-text",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "AdverseEvent-mii-pr-onko-nebenwirkung-text",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-nebenwirkung-adverse-event#nebenwirkung-grad3-art"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-nebenwirkung-adverse-event|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: nebenwirkung-grad3-art: 'Bei CTCAE-Schweregrad 3, 4 oder 5 muss die Art der Nebenwirkung (event.coding) angegeben sein. Bei Grad 1/2 darf sie fehlen (oBDS 15.2). (seriousness.coding.where(system = 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-nebenwirkung-ctcae-grad' and (code = '3' or code = '4' or code = '5')).exists() implies event.coding.exists())' (defined in https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-nebenwirkung-adverse-event)"
            },
            "expression": [
              "AdverseEvent/mii-pr-onko-nebenwirkung-text: AdverseEvent"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Bundle-mii-exa-onko-cup-bundle",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Bundle-mii-exa-onko-cup-bundle",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 93
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://terminology.hl7.org/CodeSystem/icd-o-3#C80.9 ('Unbekannte Primärlokalisation')'' in ValueSet."
            },
            "expression": [
              "Bundle/mii-exa-onko-cup-bundle: Bundle.entry[1].resource/*Condition/mii-exa-onko-cup-diagnose*/.bodySite[0].coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 93
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://terminology.hl7.org/CodeSystem/icd-o-3#C80.9 ('Unbekannte Primärlokalisation')'' in ValueSet."
            },
            "expression": [
              "Bundle/mii-exa-onko-cup-bundle: Bundle.entry[1].resource/*Condition/mii-exa-onko-cup-diagnose*/.bodySite[0].coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 127
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-cup-bundle: Bundle.entry[2].resource/*Observation/mii-exa-onko-cup-tnm-t-cTX*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 194
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-cup-bundle: Bundle.entry[3].resource/*Observation/mii-exa-onko-cup-tnm-n-cNX*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 261
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-cup-bundle: Bundle.entry[4].resource/*Observation/mii-exa-onko-cup-tnm-m-cM1*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 269
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Bundle/mii-exa-onko-cup-bundle: Bundle.entry[4].resource/*Observation/mii-exa-onko-cup-tnm-m-cM1*/.value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 269
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Bundle/mii-exa-onko-cup-bundle: Bundle.entry[4].resource/*Observation/mii-exa-onko-cup-tnm-m-cM1*/.value.ofType(CodeableConcept).coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 333
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-cup-bundle: Bundle.entry[5].resource/*Observation/mii-exa-onko-cup-tnm-klassifikation*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 388
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-cup-bundle: Bundle.entry[6].resource/*Observation/mii-exa-onko-cup-fernmetastase-hep*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 431
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-cup-bundle: Bundle.entry[7].resource/*Observation/mii-exa-onko-cup-fernmetastase-pul*/"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Bundle-mii-exa-onko-folfox-workflow-bundle",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Bundle-mii-exa-onko-folfox-workflow-bundle",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 87
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/sid/patienten'"
            },
            "expression": [
              "Bundle/mii-exa-onko-folfox-workflow-bundle: Bundle.entry[0].resource/*Patient/mii-exa-onko-folfox-patient*/.identifier[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 116
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor#onko-icd-meldepflicht"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: onko-icd-meldepflicht: 'Der ICD-10-GM-Code sollte aus der Menge der krebsregister-meldepflichtigen Neubildungen stammen (C00-C97, D00-D09, D32-D33, D35.2-D35.4, D37-D48). Andere Codes sind zulässig, aber untypisch für eine onkologische Primärdiagnose. ($this.memberOf('https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-icd10-meldepflichtige-tumoren'))' (defined in https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor)"
            },
            "expression": [
              "Bundle/mii-exa-onko-folfox-workflow-bundle: Bundle.entry[4].resource/*Condition/mii-exa-onko-colorectal-cancer-diagnosis*/.code.coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 157
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-folfox-workflow-bundle: Bundle.entry[5].resource/*Observation/mii-exa-onko-colorectal-tnm-t*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 217
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-folfox-workflow-bundle: Bundle.entry[6].resource/*Observation/mii-exa-onko-colorectal-tnm-n*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 277
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-folfox-workflow-bundle: Bundle.entry[7].resource/*Observation/mii-exa-onko-colorectal-tnm-m*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 337
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-folfox-workflow-bundle: Bundle.entry[8].resource/*Observation/mii-exa-onko-colorectal-tnm*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 529
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01BC02 ('Fluorouracil')'' in ValueSet."
            },
            "expression": [
              "Bundle/mii-exa-onko-folfox-workflow-bundle: Bundle.entry[11].resource/*MedicationRequest/mii-exa-onko-folfox-5fu-request*/.medication.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 529
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01BC02 ('Fluorouracil')'' in ValueSet."
            },
            "expression": [
              "Bundle/mii-exa-onko-folfox-workflow-bundle: Bundle.entry[11].resource/*MedicationRequest/mii-exa-onko-folfox-5fu-request*/.medication.ofType(CodeableConcept).coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 544
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Reference_REF_MultipleMatches"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "structure",
            "details": {
              "text": "Found multiple matching profiles for Condition/mii-exa-onko-colorectal-cancer-diagnosis among choices: http://hl7.org/fhir/StructureDefinition/Condition|4.0.1, https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
            },
            "expression": [
              "Bundle/mii-exa-onko-folfox-workflow-bundle: Bundle.entry[11].resource/*MedicationRequest/mii-exa-onko-folfox-5fu-request*/.reasonReference[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 562
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#V03AF03 ('Calciumfolinat')'' in ValueSet."
            },
            "expression": [
              "Bundle/mii-exa-onko-folfox-workflow-bundle: Bundle.entry[12].resource/*MedicationRequest/mii-exa-onko-folfox-leucovorin-request*/.medication.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 562
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#V03AF03 ('Calciumfolinat')'' in ValueSet."
            },
            "expression": [
              "Bundle/mii-exa-onko-folfox-workflow-bundle: Bundle.entry[12].resource/*MedicationRequest/mii-exa-onko-folfox-leucovorin-request*/.medication.ofType(CodeableConcept).coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 577
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Reference_REF_MultipleMatches"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "structure",
            "details": {
              "text": "Found multiple matching profiles for Condition/mii-exa-onko-colorectal-cancer-diagnosis among choices: http://hl7.org/fhir/StructureDefinition/Condition|4.0.1, https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
            },
            "expression": [
              "Bundle/mii-exa-onko-folfox-workflow-bundle: Bundle.entry[12].resource/*MedicationRequest/mii-exa-onko-folfox-leucovorin-request*/.reasonReference[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 595
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01XA03 ('Oxaliplatin')'' in ValueSet."
            },
            "expression": [
              "Bundle/mii-exa-onko-folfox-workflow-bundle: Bundle.entry[13].resource/*MedicationRequest/mii-exa-onko-folfox-oxaliplatin-request*/.medication.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 595
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01XA03 ('Oxaliplatin')'' in ValueSet."
            },
            "expression": [
              "Bundle/mii-exa-onko-folfox-workflow-bundle: Bundle.entry[13].resource/*MedicationRequest/mii-exa-onko-folfox-oxaliplatin-request*/.medication.ofType(CodeableConcept).coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 610
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Reference_REF_MultipleMatches"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "structure",
            "details": {
              "text": "Found multiple matching profiles for Condition/mii-exa-onko-colorectal-cancer-diagnosis among choices: http://hl7.org/fhir/StructureDefinition/Condition|4.0.1, https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
            },
            "expression": [
              "Bundle/mii-exa-onko-folfox-workflow-bundle: Bundle.entry[13].resource/*MedicationRequest/mii-exa-onko-folfox-oxaliplatin-request*/.reasonReference[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 678
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Reference_REF_MultipleMatches"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "structure",
            "details": {
              "text": "Found multiple matching profiles for Condition/mii-exa-onko-colorectal-cancer-diagnosis among choices: http://hl7.org/fhir/StructureDefinition/Condition|4.0.1, https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
            },
            "expression": [
              "Bundle/mii-exa-onko-folfox-workflow-bundle: Bundle.entry[14].resource/*Procedure/mii-exa-onko-sigmoid-resection*/.reasonReference[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 741
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Reference_REF_MultipleMatches"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "structure",
            "details": {
              "text": "Found multiple matching profiles for Condition/mii-exa-onko-colorectal-cancer-diagnosis among choices: http://hl7.org/fhir/StructureDefinition/Condition|4.0.1, https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
            },
            "expression": [
              "Bundle/mii-exa-onko-folfox-workflow-bundle: Bundle.entry[15].resource/*Procedure/mii-exa-onko-sigmoid-resection-part1*/.reasonReference[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 809
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Reference_REF_MultipleMatches"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "structure",
            "details": {
              "text": "Found multiple matching profiles for Condition/mii-exa-onko-colorectal-cancer-diagnosis among choices: http://hl7.org/fhir/StructureDefinition/Condition|4.0.1, https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
            },
            "expression": [
              "Bundle/mii-exa-onko-folfox-workflow-bundle: Bundle.entry[16].resource/*Procedure/mii-exa-onko-sigmoid-resection-part2*/.reasonReference[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 877
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Reference_REF_MultipleMatches"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "structure",
            "details": {
              "text": "Found multiple matching profiles for Condition/mii-exa-onko-colorectal-cancer-diagnosis among choices: http://hl7.org/fhir/StructureDefinition/Condition|4.0.1, https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
            },
            "expression": [
              "Bundle/mii-exa-onko-folfox-workflow-bundle: Bundle.entry[17].resource/*Procedure/mii-exa-onko-sigmoid-resection-part3*/.reasonReference[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 929
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tumorkonferenz|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-systemische-therapie-art' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Bundle/mii-exa-onko-folfox-workflow-bundle: Bundle.entry[18].resource/*Procedure/mii-exa-onko-folfox-procedure*/.code.coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 961
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Reference_REF_MultipleMatches"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "structure",
            "details": {
              "text": "Found multiple matching profiles for Condition/mii-exa-onko-colorectal-cancer-diagnosis among choices: http://hl7.org/fhir/StructureDefinition/Condition|4.0.1, https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
            },
            "expression": [
              "Bundle/mii-exa-onko-folfox-workflow-bundle: Bundle.entry[18].resource/*Procedure/mii-exa-onko-folfox-procedure*/.reasonReference[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1013
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01BC02 ('Fluorouracil')'' in ValueSet."
            },
            "expression": [
              "Bundle/mii-exa-onko-folfox-workflow-bundle: Bundle.entry[19].resource/*MedicationStatement/mii-exa-onko-folfox-5fu-statement*/.medication.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1013
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01BC02 ('Fluorouracil')'' in ValueSet."
            },
            "expression": [
              "Bundle/mii-exa-onko-folfox-workflow-bundle: Bundle.entry[19].resource/*MedicationStatement/mii-exa-onko-folfox-5fu-statement*/.medication.ofType(CodeableConcept).coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1058
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#V03AF03 ('Calciumfolinat')'' in ValueSet."
            },
            "expression": [
              "Bundle/mii-exa-onko-folfox-workflow-bundle: Bundle.entry[20].resource/*MedicationStatement/mii-exa-onko-folfox-leucovorin-statement*/.medication.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1058
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#V03AF03 ('Calciumfolinat')'' in ValueSet."
            },
            "expression": [
              "Bundle/mii-exa-onko-folfox-workflow-bundle: Bundle.entry[20].resource/*MedicationStatement/mii-exa-onko-folfox-leucovorin-statement*/.medication.ofType(CodeableConcept).coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1103
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01XA03 ('Oxaliplatin')'' in ValueSet."
            },
            "expression": [
              "Bundle/mii-exa-onko-folfox-workflow-bundle: Bundle.entry[21].resource/*MedicationStatement/mii-exa-onko-folfox-oxaliplatin-statement*/.medication.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1103
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01XA03 ('Oxaliplatin')'' in ValueSet."
            },
            "expression": [
              "Bundle/mii-exa-onko-folfox-workflow-bundle: Bundle.entry[21].resource/*MedicationStatement/mii-exa-onko-folfox-oxaliplatin-statement*/.medication.ofType(CodeableConcept).coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1138
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-folfox-workflow-bundle: Bundle.entry[22].resource/*Observation/mii-exa-onko-folfox-verlauf-6months*/"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Bundle-mii-exa-onko-kim-musterperson-synthesized",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Bundle-mii-exa-onko-kim-musterperson-synthesized",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 80
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Bundle|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.identifier.system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 66
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor#onko-icd-meldepflicht"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: onko-icd-meldepflicht: 'Der ICD-10-GM-Code sollte aus der Menge der krebsregister-meldepflichtigen Neubildungen stammen (C00-C97, D00-D09, D32-D33, D35.2-D35.4, D37-D48). Andere Codes sind zulässig, aber untypisch für eine onkologische Primärdiagnose. ($this.memberOf('https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-icd10-meldepflichtige-tumoren'))' (defined in https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor)"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[1].resource/*Condition/mii-exa-onko-kim-synth-diagnose*/.code.coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 102
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[2].resource/*Observation/mii-exa-onko-kim-klass1-cT3c*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 110
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[2].resource/*Observation/mii-exa-onko-kim-klass1-cT3c*/.value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 110
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[2].resource/*Observation/mii-exa-onko-kim-klass1-cT3c*/.value.ofType(CodeableConcept).coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 169
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[3].resource/*Observation/mii-exa-onko-kim-klass1-cN1*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 177
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[3].resource/*Observation/mii-exa-onko-kim-klass1-cN1*/.value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 177
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[3].resource/*Observation/mii-exa-onko-kim-klass1-cN1*/.value.ofType(CodeableConcept).coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 236
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[4].resource/*Observation/mii-exa-onko-kim-klass1-cM1*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 244
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[4].resource/*Observation/mii-exa-onko-kim-klass1-cM1*/.value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 244
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[4].resource/*Observation/mii-exa-onko-kim-klass1-cM1*/.value.ofType(CodeableConcept).coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 303
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[5].resource/*Observation/mii-exa-onko-kim-klass1*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 367
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[6].resource/*Observation/mii-exa-onko-kim-klass2-ycT3c*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 389
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[6].resource/*Observation/mii-exa-onko-kim-klass2-ycT3c*/.value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 389
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[6].resource/*Observation/mii-exa-onko-kim-klass2-ycT3c*/.value.ofType(CodeableConcept).coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 448
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[7].resource/*Observation/mii-exa-onko-kim-klass2-ycN1*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 470
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[7].resource/*Observation/mii-exa-onko-kim-klass2-ycN1*/.value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 470
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[7].resource/*Observation/mii-exa-onko-kim-klass2-ycN1*/.value.ofType(CodeableConcept).coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 529
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[8].resource/*Observation/mii-exa-onko-kim-klass2-ycM1b*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 551
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[8].resource/*Observation/mii-exa-onko-kim-klass2-ycM1b*/.value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 551
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[8].resource/*Observation/mii-exa-onko-kim-klass2-ycM1b*/.value.ofType(CodeableConcept).coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 610
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[9].resource/*Observation/mii-exa-onko-kim-klass2-ysym*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 657
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[10].resource/*Observation/mii-exa-onko-kim-klass2*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 724
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[11].resource/*Observation/mii-exa-onko-kim-klass3-ypT3c*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 746
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[11].resource/*Observation/mii-exa-onko-kim-klass3-ypT3c*/.value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 746
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[11].resource/*Observation/mii-exa-onko-kim-klass3-ypT3c*/.value.ofType(CodeableConcept).coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 805
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[12].resource/*Observation/mii-exa-onko-kim-klass3-ypM1b*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 827
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[12].resource/*Observation/mii-exa-onko-kim-klass3-ypM1b*/.value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 827
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[12].resource/*Observation/mii-exa-onko-kim-klass3-ypM1b*/.value.ofType(CodeableConcept).coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 886
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[13].resource/*Observation/mii-exa-onko-kim-klass3-L1*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 934
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[14].resource/*Observation/mii-exa-onko-kim-klass3-V0*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 982
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[15].resource/*Observation/mii-exa-onko-kim-klass3-Pn0*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1030
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[16].resource/*Observation/mii-exa-onko-kim-klass3-ysym*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1077
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[17].resource/*Observation/mii-exa-onko-kim-klass3*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1150
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[18].resource/*Observation/mii-exa-onko-kim-synth1*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1222
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[19].resource/*Observation/mii-exa-onko-kim-synth2*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1297
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[20].resource/*Observation/mii-exa-onko-kim-synth3*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1384
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-kim-musterperson-synthesized: Bundle.entry[21].resource/*Observation/mii-exa-onko-kim-synth4*/"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Bundle-mii-exa-onko-krk-bundle",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Bundle-mii-exa-onko-krk-bundle",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 80
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Bundle|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "Bundle/mii-exa-onko-krk-bundle: Bundle.identifier.system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 80
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor#onko-icd-meldepflicht"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: onko-icd-meldepflicht: 'Der ICD-10-GM-Code sollte aus der Menge der krebsregister-meldepflichtigen Neubildungen stammen (C00-C97, D00-D09, D32-D33, D35.2-D35.4, D37-D48). Andere Codes sind zulässig, aber untypisch für eine onkologische Primärdiagnose. ($this.memberOf('https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-icd10-meldepflichtige-tumoren'))' (defined in https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor)"
            },
            "expression": [
              "Bundle/mii-exa-onko-krk-bundle: Bundle.entry[1].resource/*Condition/mii-exa-onko-krk-diagnose*/.code.coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 120
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-krk-bundle: Bundle.entry[3].resource/*Observation/mii-exa-onko-krk-abstand-tumor-anokutanlinie*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 137
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_PassThrough_TX_Message"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Encounter|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Resolved system http://unitsofmeasure.org (v3.0.1), but the definition doesn't include any codes, so the code has not been validated (for 'http://unitsofmeasure.org#cm')"
            },
            "expression": [
              "Bundle/mii-exa-onko-krk-bundle: Bundle.entry[3].resource/*Observation/mii-exa-onko-krk-abstand-tumor-anokutanlinie*/.value.ofType(Quantity)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 164
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-krk-bundle: Bundle.entry[4].resource/*Observation/mii-exa-onko-krk-abstand-circumferelle-resektionsebene*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 172
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_PassThrough_TX_Message"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Encounter|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Resolved system http://unitsofmeasure.org (v3.0.1), but the definition doesn't include any codes, so the code has not been validated (for 'http://unitsofmeasure.org#mm')"
            },
            "expression": [
              "Bundle/mii-exa-onko-krk-bundle: Bundle.entry[4].resource/*Observation/mii-exa-onko-krk-abstand-circumferelle-resektionsebene*/.value.ofType(Quantity)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 208
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-krk-bundle: Bundle.entry[5].resource/*Observation/mii-exa-onko-krk-abstand-resektionsrand-aboral*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 216
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_PassThrough_TX_Message"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Encounter|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Resolved system http://unitsofmeasure.org (v3.0.1), but the definition doesn't include any codes, so the code has not been validated (for 'http://unitsofmeasure.org#mm')"
            },
            "expression": [
              "Bundle/mii-exa-onko-krk-bundle: Bundle.entry[5].resource/*Observation/mii-exa-onko-krk-abstand-resektionsrand-aboral*/.value.ofType(Quantity)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 252
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-krk-bundle: Bundle.entry[6].resource/*Observation/mii-exa-onko-krk-abstand-mesorektale-fascie*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 269
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_PassThrough_TX_Message"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Encounter|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Resolved system http://unitsofmeasure.org (v3.0.1), but the definition doesn't include any codes, so the code has not been validated (for 'http://unitsofmeasure.org#mm')"
            },
            "expression": [
              "Bundle/mii-exa-onko-krk-bundle: Bundle.entry[6].resource/*Observation/mii-exa-onko-krk-abstand-mesorektale-fascie*/.value.ofType(Quantity)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 296
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-krk-bundle: Bundle.entry[7].resource/*Observation/mii-exa-onko-krk-anastomoseninsuffizienz*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 343
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-krk-bundle: Bundle.entry[8].resource/*Observation/mii-exa-onko-asa-klassifikation*/"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Bundle-mii-exa-onko-mamma-example-bundle-1",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Bundle-mii-exa-onko-mamma-example-bundle-1",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 80
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Bundle|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "Bundle/mii-exa-onko-mamma-example-bundle-1: Bundle.identifier.system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 64
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor#onko-icd-meldepflicht"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: onko-icd-meldepflicht: 'Der ICD-10-GM-Code sollte aus der Menge der krebsregister-meldepflichtigen Neubildungen stammen (C00-C97, D00-D09, D32-D33, D35.2-D35.4, D37-D48). Andere Codes sind zulässig, aber untypisch für eine onkologische Primärdiagnose. ($this.memberOf('https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-icd10-meldepflichtige-tumoren'))' (defined in https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor)"
            },
            "expression": [
              "Bundle/mii-exa-onko-mamma-example-bundle-1: Bundle.entry[1].resource/*Condition/mii-exa-onko-mamma-diagnose*/.code.coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 120
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-mamma-example-bundle-1: Bundle.entry[3].resource/*Observation/mii-exa-onko-mamma-menopause-status-1*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 120
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_an_effectiveDateTime_or_an_effectivePeriod"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have an effective[x] ()"
            },
            "expression": [
              "Bundle/mii-exa-onko-mamma-example-bundle-1: Bundle.entry[3].resource/*Observation/mii-exa-onko-mamma-menopause-status-1*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 163
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-mamma-example-bundle-1: Bundle.entry[4].resource/*Observation/mii-exa-onko-mamma-rezeptorstatus-estrogen-1*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 163
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_an_effectiveDateTime_or_an_effectivePeriod"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have an effective[x] ()"
            },
            "expression": [
              "Bundle/mii-exa-onko-mamma-example-bundle-1: Bundle.entry[4].resource/*Observation/mii-exa-onko-mamma-rezeptorstatus-estrogen-1*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 244
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-mamma-example-bundle-1: Bundle.entry[5].resource/*Observation/mii-exa-onko-mamma-rezeptorstatus-progesteron-1*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 244
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_an_effectiveDateTime_or_an_effectivePeriod"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have an effective[x] ()"
            },
            "expression": [
              "Bundle/mii-exa-onko-mamma-example-bundle-1: Bundle.entry[5].resource/*Observation/mii-exa-onko-mamma-rezeptorstatus-progesteron-1*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 325
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-mamma-example-bundle-1: Bundle.entry[6].resource/*Observation/mii-exa-onko-mamma-tumorgroesse-1*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 347
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_PassThrough_TX_Message"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Resolved system http://unitsofmeasure.org (v3.0.1), but the definition doesn't include any codes, so the code has not been validated (for 'http://unitsofmeasure.org#mm')"
            },
            "expression": [
              "Bundle/mii-exa-onko-mamma-example-bundle-1: Bundle.entry[6].resource/*Observation/mii-exa-onko-mamma-tumorgroesse-1*/.value.ofType(Quantity)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 389
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "INACTIVE_CONCEPT_FOUND"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Procedure|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The concept '103693007' has a status of inactive and its use should be reviewed"
            },
            "expression": [
              "Bundle/mii-exa-onko-mamma-example-bundle-1: Bundle.entry[7].resource/*Procedure/mii-exa-onko-mamma-praeoperative-markierung-1*/.category.coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Bundle-mii-exa-onko-melanom-bundle",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Bundle-mii-exa-onko-melanom-bundle",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 80
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Bundle|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "Bundle/mii-exa-onko-melanom-bundle: Bundle.identifier.system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 85
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor#onko-icd-meldepflicht"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: onko-icd-meldepflicht: 'Der ICD-10-GM-Code sollte aus der Menge der krebsregister-meldepflichtigen Neubildungen stammen (C00-C97, D00-D09, D32-D33, D35.2-D35.4, D37-D48). Andere Codes sind zulässig, aber untypisch für eine onkologische Primärdiagnose. ($this.memberOf('https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-icd10-meldepflichtige-tumoren'))' (defined in https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor)"
            },
            "expression": [
              "Bundle/mii-exa-onko-melanom-bundle: Bundle.entry[1].resource/*Condition/mii-exa-onko-melanom-diagnose*/.code.coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 128
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-melanom-bundle: Bundle.entry[3].resource/*Observation/mii-exa-onko-melanom-sicherheitsabstand*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 145
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_PassThrough_TX_Message"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Encounter|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Resolved system http://unitsofmeasure.org (v3.0.1), but the definition doesn't include any codes, so the code has not been validated (for 'http://unitsofmeasure.org#mm')"
            },
            "expression": [
              "Bundle/mii-exa-onko-melanom-bundle: Bundle.entry[3].resource/*Observation/mii-exa-onko-melanom-sicherheitsabstand*/.value.ofType(Quantity)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 172
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-melanom-bundle: Bundle.entry[4].resource/*Observation/mii-exa-onko-melanom-breslow-tiefe*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 189
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_PassThrough_TX_Message"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Encounter|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Resolved system http://unitsofmeasure.org (v3.0.1), but the definition doesn't include any codes, so the code has not been validated (for 'http://unitsofmeasure.org#mm')"
            },
            "expression": [
              "Bundle/mii-exa-onko-melanom-bundle: Bundle.entry[4].resource/*Observation/mii-exa-onko-melanom-breslow-tiefe*/.value.ofType(Quantity)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 225
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-melanom-bundle: Bundle.entry[5].resource/*Observation/mii-exa-onko-melanom-ulzeration*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 281
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-melanom-bundle: Bundle.entry[6].resource/*Observation/mii-exa-onko-melanom-ldh*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 300
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_PassThrough_TX_Message"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Encounter|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Resolved system http://unitsofmeasure.org (v3.0.1), but the definition doesn't include any codes, so the code has not been validated (for 'http://unitsofmeasure.org#U/L')"
            },
            "expression": [
              "Bundle/mii-exa-onko-melanom-bundle: Bundle.entry[6].resource/*Observation/mii-exa-onko-melanom-ldh*/.value.ofType(Quantity)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 330
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_PassThrough_TX_Message"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Encounter|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Resolved system http://unitsofmeasure.org (v3.0.1), but the definition doesn't include any codes, so the code has not been validated (for 'http://unitsofmeasure.org#U/L')"
            },
            "expression": [
              "Bundle/mii-exa-onko-melanom-bundle: Bundle.entry[6].resource/*Observation/mii-exa-onko-melanom-ldh*/.referenceRange[0].low"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 336
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_PassThrough_TX_Message"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Encounter|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Resolved system http://unitsofmeasure.org (v3.0.1), but the definition doesn't include any codes, so the code has not been validated (for 'http://unitsofmeasure.org#U/L')"
            },
            "expression": [
              "Bundle/mii-exa-onko-melanom-bundle: Bundle.entry[6].resource/*Observation/mii-exa-onko-melanom-ldh*/.referenceRange[0].high"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 427
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Reference_REF_MultipleMatches"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "structure",
            "details": {
              "text": "Found multiple matching profiles for Condition/mii-exa-onko-melanom-diagnose among choices: http://hl7.org/fhir/StructureDefinition/Condition|4.0.1, https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
            },
            "expression": [
              "Bundle/mii-exa-onko-melanom-bundle: Bundle.entry[7].resource/*Procedure/mii-exa-onko-melanom-exzision-oberarm*/.reasonReference[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Bundle-mii-exa-onko-prostata-example-bundle-1",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Bundle-mii-exa-onko-prostata-example-bundle-1",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 80
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Bundle|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "Bundle/mii-exa-onko-prostata-example-bundle-1: Bundle.identifier.system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 64
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor#onko-icd-meldepflicht"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: onko-icd-meldepflicht: 'Der ICD-10-GM-Code sollte aus der Menge der krebsregister-meldepflichtigen Neubildungen stammen (C00-C97, D00-D09, D32-D33, D35.2-D35.4, D37-D48). Andere Codes sind zulässig, aber untypisch für eine onkologische Primärdiagnose. ($this.memberOf('https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-icd10-meldepflichtige-tumoren'))' (defined in https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor)"
            },
            "expression": [
              "Bundle/mii-exa-onko-prostata-example-bundle-1: Bundle.entry[1].resource/*Condition/mii-exa-onko-prostata-diagnose*/.code.coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 120
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-prostata-example-bundle-1: Bundle.entry[3].resource/*Observation/mii-exa-onko-prostata-psa-diagnose-1*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 159
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-prostata-example-bundle-1: Bundle.entry[4].resource/*Observation/mii-exa-onko-prostata-anzahl-stanzen-1*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 195
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-prostata-example-bundle-1: Bundle.entry[5].resource/*Observation/mii-exa-onko-prostata-anzahl-positiver-stanzen-1*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 231
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-prostata-example-bundle-1: Bundle.entry[6].resource/*Observation/mii-exa-onko-prostata-ca-befall-stanze-1*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 273
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-prostata-example-bundle-1: Bundle.entry[7].resource/*Observation/mii-exa-onko-prostata-gleason-pattern-grade-group-1*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 330
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-prostata-example-bundle-1: Bundle.entry[8].resource/*Observation/mii-exa-onko-prostata-gleason-pattern-primary-1*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 379
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-prostata-example-bundle-1: Bundle.entry[9].resource/*Observation/mii-exa-onko-prostata-gleason-pattern-secondary-1*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 428
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-prostata-example-bundle-1: Bundle.entry[10].resource/*Observation/mii-exa-onko-prostata-surgical-complication-1*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 445
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-prostata-postsurgical-complications' version 'null' could not be found, so the code cannot be validated. No versions of this code system are known"
            },
            "expression": [
              "Bundle/mii-exa-onko-prostata-example-bundle-1: Bundle.entry[10].resource/*Observation/mii-exa-onko-prostata-surgical-complication-1*/.value.ofType(CodeableConcept).coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 526
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Reference_REF_MultipleMatches"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "structure",
            "details": {
              "text": "Found multiple matching profiles for Condition/mii-exa-onko-prostata-diagnose among choices: http://hl7.org/fhir/StructureDefinition/Condition|4.0.1, https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
            },
            "expression": [
              "Bundle/mii-exa-onko-prostata-example-bundle-1: Bundle.entry[11].resource.reasonReference[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Bundle-mii-exa-onko-tnm-bundle-legacy",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Bundle-mii-exa-onko-tnm-bundle-legacy",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 80
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Bundle|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle-legacy: Bundle.identifier.system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 66
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor#onko-icd-meldepflicht"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: onko-icd-meldepflicht: 'Der ICD-10-GM-Code sollte aus der Menge der krebsregister-meldepflichtigen Neubildungen stammen (C00-C97, D00-D09, D32-D33, D35.2-D35.4, D37-D48). Andere Codes sind zulässig, aber untypisch für eine onkologische Primärdiagnose. ($this.memberOf('https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-icd10-meldepflichtige-tumoren'))' (defined in https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor)"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle-legacy: Bundle.entry[1].resource/*Condition/mii-exa-onko-tnm-bundle-legacy-diagnose*/.code.coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 102
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle-legacy: Bundle.entry[2].resource/*Observation/mii-exa-onko-tnm-bundle-legacy-t-cT2*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 164
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle-legacy: Bundle.entry[3].resource/*Observation/mii-exa-onko-tnm-bundle-legacy-n-cN3*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 226
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle-legacy: Bundle.entry[4].resource/*Observation/mii-exa-onko-tnm-bundle-legacy-m-cM0*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 288
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle-legacy: Bundle.entry[5].resource/*Observation/mii-exa-onko-tnm-bundle-legacy-klassifikation-cT2cN3cM0*/"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Bundle-mii-exa-onko-tnm-bundle-synthesized",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Bundle-mii-exa-onko-tnm-bundle-synthesized",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 80
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Bundle|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle-synthesized: Bundle.identifier.system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 66
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor#onko-icd-meldepflicht"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: onko-icd-meldepflicht: 'Der ICD-10-GM-Code sollte aus der Menge der krebsregister-meldepflichtigen Neubildungen stammen (C00-C97, D00-D09, D32-D33, D35.2-D35.4, D37-D48). Andere Codes sind zulässig, aber untypisch für eine onkologische Primärdiagnose. ($this.memberOf('https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-icd10-meldepflichtige-tumoren'))' (defined in https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor)"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle-synthesized: Bundle.entry[1].resource/*Condition/mii-exa-onko-tnm-synth-diagnose*/.code.coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 102
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle-synthesized: Bundle.entry[2].resource/*Observation/mii-exa-onko-tnm-synth-meldung1-t-cT3*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 110
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle-synthesized: Bundle.entry[2].resource/*Observation/mii-exa-onko-tnm-synth-meldung1-t-cT3*/.value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 110
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle-synthesized: Bundle.entry[2].resource/*Observation/mii-exa-onko-tnm-synth-meldung1-t-cT3*/.value.ofType(CodeableConcept).coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 169
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle-synthesized: Bundle.entry[3].resource/*Observation/mii-exa-onko-tnm-synth-meldung1-n-cN2*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 177
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle-synthesized: Bundle.entry[3].resource/*Observation/mii-exa-onko-tnm-synth-meldung1-n-cN2*/.value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 177
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle-synthesized: Bundle.entry[3].resource/*Observation/mii-exa-onko-tnm-synth-meldung1-n-cN2*/.value.ofType(CodeableConcept).coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 236
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle-synthesized: Bundle.entry[4].resource/*Observation/mii-exa-onko-tnm-synth-meldung1-m-cM0*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 244
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle-synthesized: Bundle.entry[4].resource/*Observation/mii-exa-onko-tnm-synth-meldung1-m-cM0*/.value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 244
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle-synthesized: Bundle.entry[4].resource/*Observation/mii-exa-onko-tnm-synth-meldung1-m-cM0*/.value.ofType(CodeableConcept).coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 303
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle-synthesized: Bundle.entry[5].resource/*Observation/mii-exa-onko-tnm-synth-meldung1-klassifikation*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 367
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle-synthesized: Bundle.entry[6].resource/*Observation/mii-exa-onko-tnm-synth-meldung2-t-pT2*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 375
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle-synthesized: Bundle.entry[6].resource/*Observation/mii-exa-onko-tnm-synth-meldung2-t-pT2*/.value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 375
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle-synthesized: Bundle.entry[6].resource/*Observation/mii-exa-onko-tnm-synth-meldung2-t-pT2*/.value.ofType(CodeableConcept).coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 434
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle-synthesized: Bundle.entry[7].resource/*Observation/mii-exa-onko-tnm-synth-meldung2-n-pN1*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 442
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle-synthesized: Bundle.entry[7].resource/*Observation/mii-exa-onko-tnm-synth-meldung2-n-pN1*/.value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 442
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle-synthesized: Bundle.entry[7].resource/*Observation/mii-exa-onko-tnm-synth-meldung2-n-pN1*/.value.ofType(CodeableConcept).coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 501
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle-synthesized: Bundle.entry[8].resource/*Observation/mii-exa-onko-tnm-synth-meldung2-klassifikation*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 562
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle-synthesized: Bundle.entry[9].resource/*Observation/mii-exa-onko-tnm-synth-klassifikation*/"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Bundle-mii-exa-onko-tnm-bundle",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Bundle-mii-exa-onko-tnm-bundle",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 80
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Bundle|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle: Bundle.identifier.system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 66
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor#onko-icd-meldepflicht"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: onko-icd-meldepflicht: 'Der ICD-10-GM-Code sollte aus der Menge der krebsregister-meldepflichtigen Neubildungen stammen (C00-C97, D00-D09, D32-D33, D35.2-D35.4, D37-D48). Andere Codes sind zulässig, aber untypisch für eine onkologische Primärdiagnose. ($this.memberOf('https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-icd10-meldepflichtige-tumoren'))' (defined in https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor)"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle: Bundle.entry[1].resource/*Condition/mii-exa-onko-tnm-bundle-diagnose*/.code.coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 102
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle: Bundle.entry[2].resource/*Observation/mii-exa-onko-tnm-bundle-t-kategorie-cT2*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 110
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle: Bundle.entry[2].resource/*Observation/mii-exa-onko-tnm-bundle-t-kategorie-cT2*/.value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 110
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle: Bundle.entry[2].resource/*Observation/mii-exa-onko-tnm-bundle-t-kategorie-cT2*/.value.ofType(CodeableConcept).coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 169
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle: Bundle.entry[3].resource/*Observation/mii-exa-onko-tnm-bundle-n-kategorie-cN3*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 177
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle: Bundle.entry[3].resource/*Observation/mii-exa-onko-tnm-bundle-n-kategorie-cN3*/.value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 177
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle: Bundle.entry[3].resource/*Observation/mii-exa-onko-tnm-bundle-n-kategorie-cN3*/.value.ofType(CodeableConcept).coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 236
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle: Bundle.entry[4].resource/*Observation/mii-exa-onko-tnm-bundle-m-kategorie-cM0*/"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 244
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle: Bundle.entry[4].resource/*Observation/mii-exa-onko-tnm-bundle-m-kategorie-cM0*/.value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 244
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle: Bundle.entry[4].resource/*Observation/mii-exa-onko-tnm-bundle-m-kategorie-cM0*/.value.ofType(CodeableConcept).coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 303
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Bundle/mii-exa-onko-tnm-bundle: Bundle.entry[5].resource/*Observation/mii-exa-onko-tnm-bundle-klassifikation-cT2cN3cM0*/"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/CapabilityStatement-mii-cps-onko-capabilitystatement",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CapabilityStatement-mii-cps-onko-capabilitystatement",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 117340
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecapabilitystatement|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CapabilityStatement/mii-cps-onko-capabilitystatement: CapabilityStatement.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 129485
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecapabilitystatement|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-allgemeiner-leistungszustand-ecog-quantity'"
            },
            "expression": [
              "CapabilityStatement/mii-cps-onko-capabilitystatement: CapabilityStatement.rest[0].resource[3].supportedProfile[22]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 129768
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecapabilitystatement|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-allgemeiner-leistungszustand-karnofsky-quantity'"
            },
            "expression": [
              "CapabilityStatement/mii-cps-onko-capabilitystatement: CapabilityStatement.rest[0].resource[3].supportedProfile[24]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 143804
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecapabilitystatement|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://www.medizininformatik-initiative.de/fhir/modul-meta/SearchParameter/mii-sp-meta-observation-note'"
            },
            "expression": [
              "CapabilityStatement/mii-cps-onko-capabilitystatement: CapabilityStatement.rest[0].resource[3].searchParam[18].definition"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 147153
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecapabilitystatement|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://www.medizininformatik-initiative.de/fhir/modul-meta/SearchParameter/mii-sp-meta-mode'"
            },
            "expression": [
              "CapabilityStatement/mii-cps-onko-capabilitystatement: CapabilityStatement.rest[0].resource[4].searchParam[4].definition"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
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              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 148063
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecapabilitystatement|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://www.medizininformatik-initiative.de/fhir/modul-meta/SearchParameter/mii-sp-meta-flag'"
            },
            "expression": [
              "CapabilityStatement/mii-cps-onko-capabilitystatement: CapabilityStatement.rest[0].resource[4].searchParam[8].definition"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
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              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 155383
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecapabilitystatement|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/SearchParameter/mii-sp-onko-procedure-ext-strahlentherapie-stellungzurop'"
            },
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              "CapabilityStatement/mii-cps-onko-capabilitystatement: CapabilityStatement.rest[0].resource[5].searchParam[15].definition"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecapabilitystatement|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/SearchParameter/mii-sp-onko-procedure-ext-strahlentherapie-bs-applikationsart'"
            },
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              "CapabilityStatement/mii-cps-onko-capabilitystatement: CapabilityStatement.rest[0].resource[5].searchParam[16].definition"
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          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecapabilitystatement|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/SearchParameter/mii-sp-onko-procedure-ext-strahlentherapie-bs-strahlenart'"
            },
            "expression": [
              "CapabilityStatement/mii-cps-onko-capabilitystatement: CapabilityStatement.rest[0].resource[5].searchParam[17].definition"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 156346
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecapabilitystatement|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/SearchParameter/mii-sp-onko-procedure-ext-strahlentherapie-bs-zielgebiet'"
            },
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              "CapabilityStatement/mii-cps-onko-capabilitystatement: CapabilityStatement.rest[0].resource[5].searchParam[18].definition"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 156678
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecapabilitystatement|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/SearchParameter/mii-sp-onko-procedure-ext-strahlentherapie-bs-lateralitaet'"
            },
            "expression": [
              "CapabilityStatement/mii-cps-onko-capabilitystatement: CapabilityStatement.rest[0].resource[5].searchParam[19].definition"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 157952
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecapabilitystatement|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/SearchParameter/mii-sp-onko-procedure-systemischetherapie-ext-intention'"
            },
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          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecapabilitystatement|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/SearchParameter/mii-sp-onko-procedure-systemischetherapie-ext-stellungzurop'"
            },
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              "CapabilityStatement/mii-cps-onko-capabilitystatement: CapabilityStatement.rest[0].resource[5].searchParam[24].definition"
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          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecapabilitystatement|2.0.0"
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            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'http://hl7.org/fhir/SearchParameter/event'"
            },
            "expression": [
              "CapabilityStatement/mii-cps-onko-capabilitystatement: CapabilityStatement.rest[0].resource[6].searchParam[3].definition"
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          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecapabilitystatement|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://www.medizininformatik-initiative.de/fhir/modul-meta/SearchParameter/mii-sp-meta-encounter'"
            },
            "expression": [
              "CapabilityStatement/mii-cps-onko-capabilitystatement: CapabilityStatement.rest[0].resource[6].searchParam[5].definition"
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          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecapabilitystatement|2.0.0"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'http://hl7.org/fhir/SearchParameter/seriousness'"
            },
            "expression": [
              "CapabilityStatement/mii-cps-onko-capabilitystatement: CapabilityStatement.rest[0].resource[6].searchParam[6].definition"
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          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecapabilitystatement|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://www.medizininformatik-initiative.de/fhir/modul-meta/SearchParameter/mii-sp-meta-instance'"
            },
            "expression": [
              "CapabilityStatement/mii-cps-onko-capabilitystatement: CapabilityStatement.rest[0].resource[6].searchParam[7].definition"
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          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecapabilitystatement|2.0.0"
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            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://www.medizininformatik-initiative.de/fhir/modul-meta/SearchParameter/mii-sp-meta-medicationstatement-based-on'"
            },
            "expression": [
              "CapabilityStatement/mii-cps-onko-capabilitystatement: CapabilityStatement.rest[0].resource[7].searchParam[3].definition"
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          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 163121
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecapabilitystatement|2.0.0"
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            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'http://hl7.org/fhir/SearchParameter/MedicationStatement-code'"
            },
            "expression": [
              "CapabilityStatement/mii-cps-onko-capabilitystatement: CapabilityStatement.rest[0].resource[7].searchParam[5].definition"
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          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecapabilitystatement|2.0.0"
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            ],
            "severity": "warning",
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            "details": {
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            },
            "expression": [
              "CodeSystem/mii-cs-onko-genetische-variante-auspraegung: CodeSystem.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7958
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-genetische-variante-auspraegung: CodeSystem.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/CodeSystem-mii-cs-onko-grading",
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        "issue": [
          {
            "extension": [
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 415
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-grading: CodeSystem.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
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            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-grading: CodeSystem.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/CodeSystem-mii-cs-onko-intention",
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        "resourceType": "OperationOutcome",
        "id": "CodeSystem-mii-cs-onko-intention",
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          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-intention: CodeSystem.meta.extension[1].extension[2].value.ofType(uri)"
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          },
          {
            "extension": [
              {
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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              {
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            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-intention: CodeSystem.jurisdiction[0].coding[0].system"
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          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/CodeSystem-mii-cs-onko-krk-anastomoseninsuffizienz",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-mii-cs-onko-krk-anastomoseninsuffizienz",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
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            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-krk-anastomoseninsuffizienz: CodeSystem.meta.extension[1].extension[2].value.ofType(uri)"
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          },
          {
            "extension": [
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
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            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-krk-anastomoseninsuffizienz: CodeSystem.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/CodeSystem-mii-cs-onko-krk-mrt-mesorektale-faszie-status",
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        "resourceType": "OperationOutcome",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
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            ],
            "severity": "warning",
            "code": "invalid",
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            "expression": [
              "CodeSystem/mii-cs-onko-krk-mrt-mesorektale-faszie-status: CodeSystem.meta.extension[1].extension[2].value.ofType(uri)"
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          {
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
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            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-krk-mrt-mesorektale-faszie-status: CodeSystem.jurisdiction[0].coding[0].system"
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          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/CodeSystem-mii-cs-onko-krk-operationstyp",
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        "resourceType": "OperationOutcome",
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        "issue": [
          {
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
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            "code": "invalid",
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            "expression": [
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          {
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            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-krk-operationstyp: CodeSystem.jurisdiction[0].coding[0].system"
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          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/CodeSystem-mii-cs-onko-krk-stoma-anzeichnung",
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
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            "expression": [
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            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
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      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/CodeSystem-mii-cs-onko-krk-tme-qualitaet",
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            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
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            },
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    {
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            "expression": [
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            "severity": "warning",
            "code": "not-found",
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            "expression": [
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    {
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            "expression": [
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              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-mamma-her2neu-status-obds: CodeSystem.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/CodeSystem-mii-cs-onko-mamma-rezeptorstatus-leitlinie",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-mii-cs-onko-mamma-rezeptorstatus-leitlinie",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 438
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-mamma-rezeptorstatus-leitlinie: CodeSystem.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7552
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-mamma-rezeptorstatus-leitlinie: CodeSystem.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/CodeSystem-mii-cs-onko-melanom-ulzeration",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-mii-cs-onko-melanom-ulzeration",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 426
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecodesystem|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-melanom-ulzeration: CodeSystem.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6804
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecodesystem|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-melanom-ulzeration: CodeSystem.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/CodeSystem-mii-cs-onko-nebenwirkung-ctcae-grad",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-mii-cs-onko-nebenwirkung-ctcae-grad",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 431
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-ctcae-grad: CodeSystem.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8271
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-ctcae-grad: CodeSystem.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/CodeSystem-mii-cs-onko-nebenwirkung-ctcae-version",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-mii-cs-onko-nebenwirkung-ctcae-version",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 434
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecodesystem|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-ctcae-version: CodeSystem.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7302
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecodesystem|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-ctcae-version: CodeSystem.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/CodeSystem-mii-cs-onko-nebenwirkung-meddra-de",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-mii-cs-onko-nebenwirkung-meddra-de",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 430
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-publishablecodesystem|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 799075
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-publishablecodesystem|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Blutarmut' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Anämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[0].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gerinnungsstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Disseminierte intravaskuläre Koagulation')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[1].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'disseminierte intravasale Koagulopathie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Disseminierte intravaskuläre Koagulation')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[1].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'ausgedehnte intravaskuläre Koagulation' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Disseminierte intravaskuläre Koagulation')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[1].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Blutauflösung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hämolyse')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[3].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Transfusionszwischenfall' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hämolyse')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[3].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Transfusionszwischenfall' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hämolytischurämisches Syndrom (HUS)')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[4].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Zellarmes Knochenmark' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypozelluläres Knochenmark')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[5].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Knochenmarkhypozellularität' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypozelluläres Knochenmark')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[5].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Erhöhung der weißen Blutkörperchen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Leukozytose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[6].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Lymphknotenschmerzen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[7].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Störung der Milzfunktion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Milzerkrankung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[8].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Erkrankung der Milz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Milzerkrankung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[8].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Thrombotischthrombozytopenische Purpura' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Thrombotische thrombozytopenische Purpura')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[9].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Moschcowitz Syndrom' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Thrombotische thrombozytopenische Purpura')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[9].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'TTP' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Thrombotische thrombozytopenische Purpura')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[9].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Störungen des hämatopoietischen und lymphoiden Systems' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Störungen des Blut- und Lymphsystems - Sonstige, zu spezifizieren')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[10].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Akute Herzstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Akutes Koronarsyndrom')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[11].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Aortenklappenstenose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Aortenklappenkrankheit')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[12].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Aortenklappeninsuffizienz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Aortenklappenkrankheit')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[12].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Herzstillstand' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Asystolie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[13].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Herzrhythmusstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Asystolie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[13].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Herzrhythmusstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('AV Block ersten Grades')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[14].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Herzrhythmusstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('AV Block, Mobitz Typ II')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[15].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Herzrhythmusstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('AV Block, vollständiger')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[16].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kompletter AV'-Block' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('AV Block, vollständiger')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[16].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Herzbeuteltamponade')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[17].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Perikarditis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Herzbeutelentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[18].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Perikarderguss' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Herzbeutelerguss')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[19].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Palpitationen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Herzklopfen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[20].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Herzrasen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Herzklopfen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[20].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Herzrhythmusstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Herzklopfen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[20].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kardialer Stillstand' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Herzstillstand')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[21].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Herzrhythmusstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Herzstillstand')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[21].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Herzinsuffizienz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Herzversagen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[22].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Herzfehler' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Herzversagen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[22].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kardiogener Schock' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Herzversagen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[22].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ventrikuläres Flimmern' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Kammerflimmern')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[23].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Herzrhythmusstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Kammerflimmern')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[23].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Angiona pectoris Schmerz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Kardialer Brustschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[24].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kardialer Thoraxschmerz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Kardialer Brustschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[24].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Systolische Dysfunktion linke Herzkammer' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Linksventrikuläre systolische Dysfunktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[25].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Mitralklappeninsuffizienz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Mitralklappenerkrankung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[26].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Mitralklappenstenose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Mitralklappenerkrankung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[26].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Mitralklappenkrankheit' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Mitralklappenerkrankung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[26].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Herzrhythmusstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Mobitz Typ I')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[27].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Herzinfarkt' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Myokardinfarkt')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[28].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Herzentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Myokarditis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[29].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Anfallsweise Vorhoftachykardie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Paroxysmale Vorhoftachykardie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[30].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Perikarditis, konstriktive')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[31].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Pulmonalklappenstenose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pulmonalklappenerkrankung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[32].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Pulmonalklappeninsuffizienz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pulmonalklappenerkrankung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[32].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'RCM' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Restriktive Kardiomyopathie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[33].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Rechtsherzdysfunktion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Rechtsventrikuläre Dysfunktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[34].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Herzrhythmusstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Sick-sinus-Syndrom')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[35].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Syndrom des kranken Sinusknotens' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Sick-sinus-Syndrom')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[35].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Herzrhythmusstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Sinusbradykardie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[36].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Herzrhythmusstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Sinustachykardie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[37].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Herzrhythmusstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Supraventrikuläre Tachykardie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[38].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Trikuspidalklappenstenose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Trikuspidalklappenerkrankung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[39].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Trikuspidalklappeninsuffizienz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Trikuspidalklappenerkrankung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[39].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Herzrhythmusstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Überleitungsstörung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[40].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Herzrhythmusstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ventrikuläre Arrhythmie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[41].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kammerarhythmie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ventrikuläre Arrhythmie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[41].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kammertachykardie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ventrikuläre Tachykardie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[42].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Herzrhythmusstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ventrikuläre Tachykardie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[42].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Herzrhythmusstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vorhofflattern')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[43].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Herzrhythmusstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vorhofflimmern')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[44].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'WPW'-Syndrom' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Wolff-Parkinson-White Syndrom (WPW)')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[45].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Herzrhythmusstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Wolff-Parkinson-White Syndrom (WPW)')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[45].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Herzerkrankungen - Sonstige, zu spezifizieren')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[46].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kongenitale, familiäre und vererbbare Krankheiten-Sonstige, zu spezifizieren' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Angeborene, familiäre und genetische Erkrankungen - Sonstige, zu spezifizieren')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[47].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hörbehinderung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Beeinträchtigung des Hörens')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[48].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hypakusis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Beeinträchtigung des Hörens')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[48].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Schwerhörigkeit' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Beeinträchtigung des Hörens')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[48].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hörminderung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Beeinträchtigung des Hörens')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[48].designation[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Otitis media' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Mittelohrentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[49].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Paukendrainage' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Mittelohrentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[49].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Paukenröhrchen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Mittelohrentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[49].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ohrenschmerzen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[50].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Entzündung des äußeren Ohres' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Otitis externa')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[51].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ohrkanalentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Otitis externa')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[51].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Äußere Ohrenschmerzen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Schmerzen des äußeren Ohres')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[52].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ohrgeräusch' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Tinnitus')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[53].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Schwindel' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vertigo')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[54].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Drehschwindel' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vertigo')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[54].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Labyrithschwindel' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vertigo')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[54].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Vestibulumerkrankung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vestibuläre Störung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[55].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gleichgewichtsstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vestibuläre Störung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[55].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ohr-, Ohrgangs- und Labyrintherkrankungen Sonstige zu spezifizieren Labyrinth' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ohr- und Innenohrerkrankungen - Sonstige, zu spezifizieren')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[56].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Cushingoid' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Cushing-ähnliches Syndrom')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[57].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Überfunktion der Nebenschilddrüsen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hyperparathyreoidismus')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[58].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Unterfunktion der Nebenschilddrüsen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypoparathyreoidismus')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[59].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Vermännlichung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Maskulinisierung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[60].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Virilisierung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Maskulinisierung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[60].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Nebennierenschwäche' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Nebenniereninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[61].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'adrenale Insuffizienz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Nebenniereninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[61].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hyperthyreoidismus' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Schilddrüsenüberfunktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[62].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hypothyreoidismus' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Schilddrüsenunterfunktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[63].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Pubertas präcox' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Verfrühte Pubertät')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[64].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Retardierte Pubertät' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Verzögerte Pubertät')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[65].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Verspätete Pubertät' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Verzögerte Pubertät')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[65].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Wachstums akzeleration' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Wachstumsbeschleunigung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[66].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Endokrine Erkrankungen - Sonstige, zu spezifizieren')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[67].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Extraokuläre Muskelparese' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Augenmuskellähmung, äußere')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[68].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Nervus opticus Erkrankung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Augennerverkrankung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[69].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hirnnervenausfall' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Augennerverkrankung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[69].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Xerophthalmie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Augentrockenheit')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[70].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'trockenes Auge' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Augentrockenheit')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[70].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Augenlidfunktionsstörung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[71].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Augenschmerzen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[72].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Blutige Glaskörperextravasation' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Glaskörperblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[73].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Grüner Star' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Glaukom')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[74].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Katarakt' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Grauer Star')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[75].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Augenlinsentrübung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Grauer Star')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[75].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Keratitis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hornhautentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[76].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ulkus der Hornhaut' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hornhautgeschwür')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[77].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'koroneales Ulcus' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hornhautgeschwür')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[77].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Nachtblindheit')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[78].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Bindehautentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Konjunktivitis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[79].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Lichtblitze')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[80].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Retinaablösung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Netzhautablösung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[81].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Retinaeinriss' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Netzhautriss')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[82].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Lichtscheu' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Photophobie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[83].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Lichtüberempfindlichkeit' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Photophobie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[83].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Netzhauterkrankung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Retinopathie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[84].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Sklera Erkrankung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Sklerale Störung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[85].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Lederhaut Erkrankung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Sklerale Störung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[85].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Papillenödem' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Stauungspapille')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[86].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Sehscheibenschwellung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Stauungspapille')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[86].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Papillenschwellung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Stauungspapille')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[86].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Wässernde Augen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Tränende Augen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[87].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Regenbogenhautentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Uveitis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[88].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vaskuläre retinale Erkrankung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[89].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Unscharfes Sehen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Verschwommenes Sehen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[90].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Augenerkrankungen - Sonstige, zu spezifizieren')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[91].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Aufgetriebener Bauch' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Abdominale Blähung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[92].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Abdominale Aufblähung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Abdominale Blähung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[92].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Bauchblähung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Abdominale Blähung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[92].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Bauchschmerzen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Abdominale Schmerzen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[93].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Bauchkrämpfe' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Abdominale Schmerzen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[93].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'abdominale Schmerzen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Abdominale Schmerzen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[93].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Afterblutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Analblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[94].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Analhämorrhagie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Analblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[94].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Analulkus' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Analgeschwür')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[96].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Analulcus' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Analgeschwür')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[96].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Anale Schleimhautentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Analmukositis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[97].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Afternekrose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Analnekrose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[98].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Afterschmerz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Analschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[99].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Analverengung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Analstenose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[100].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Afterstenose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Analstenose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[100].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Bauchwassersucht' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Aszites')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[101].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'abdominelle Flüssigkeitsansammlung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Aszites')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[101].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Flatulenz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Blähungen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[102].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Winde' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Blähungen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[102].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Untere GI- Trakt- Blutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Blutung des unteren Gastrointestinaltraktes')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[103].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Blutung distaler GI'-Trakt' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Blutung des unteren Gastrointestinaltraktes')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[103].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Peranale Blutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Blutung des unteren Gastrointestinaltraktes')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[103].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Lippenentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Cheilitis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[104].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Enteritis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Darmentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[105].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Enterokolitis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Darmentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[105].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Enterocolitis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Darmentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[105].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kolonfistel' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dickdarmfistel')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[106].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kolonhämorrhagie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dickdarmblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[107].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kolonblutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dickdarmblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[107].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kolonobstruktion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dickdarmobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[108].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Dickdarmverschluss' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dickdarmobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[108].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Darmpassagestörungen (z. B. protrahierte Atonie, Subileus, Ileus)' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dickdarmobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[108].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Dickdarmileus' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dickdarmobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[108].designation[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Dickdarmdurchbruch' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dickdarmperforation')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[109].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kolonperforation' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dickdarmperforation')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[109].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Dickdarmverengung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dickdarmstenose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[110].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kolonulcus' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dickdarmulkus')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[111].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kolonulkus' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dickdarmulkus')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[111].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Dickdarmgeschwür' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dickdarmulkus')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[111].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Dünndarmverschluss' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dünndarmobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[112].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Dünndarmmileus' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dünndarmobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[112].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Dünndarmdurchbruch' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dünndarmperforation')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[113].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Dünndarmmukositis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dünndarmschleimhautentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[114].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Dünndarmentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dünndarmschleimhautentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[114].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Dünndarmverengung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dünndarmstenose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[115].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Dünndarmulkus' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dünndarmgeschwür')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[116].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Zwölffingerdarmblutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Duodenalblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[117].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Zwölffingerdarmfistel' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Duodenalfistel')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[118].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Duodenalblutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Duodenalfistel')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[118].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Zwölffingerdarmverschluss' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Duodenalobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[119].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Duodenaldurchbruch' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Duodenalperforation')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[120].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Zwölffingerdarmdurchbruch' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Duodenalperforation')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[120].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Zwölffingerdarmperforation' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Duodenalperforation')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[120].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Zwölffingerdarmstenose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Duodenalstenose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[121].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Zwölffingerdarmverengung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Duodenalstenose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[121].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Duodenalulcus' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Duodenalstenose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[121].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ulcus duodeni' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Duodenalstenose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[121].designation[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Zwölffingerdarmgeschwür' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Duodenalulkus')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[122].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Diarrhö' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Durchfall')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[123].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Diarrhoe' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Durchfall')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[123].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Emesis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Erbrechen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[124].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Enterale Fistel' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gastrointestinale Fistel')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[125].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Bauchschmerzen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gastrointestinale Schmerzen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[126].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'abdominelle Schmerzen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gastrointestinale Schmerzen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[126].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Sodbrennen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gastroösophageale Refluxkrankheit')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[127].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Magenbrennen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gastroösophageale Refluxkrankheit')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[127].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Pyrosis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gastroösophageale Refluxkrankheit')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[127].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Refluxösophagitis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gastroösophageale Refluxkrankheit')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[127].designation[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'gastroesophageal reflux disease, GERD' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gastroösophageale Refluxkrankheit')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[127].designation[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Magenlähmung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gastroparese')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[128].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Magenatonie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gastroparese')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[128].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Magenentleerungsstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gastroparese')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[128].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Afterblutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hämorrhoidale Blutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[129].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Analhämorrhagie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hämorrhoidale Blutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[129].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hämorrhoiden')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[130].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Enterovesikale Fistel' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Harnblasen-Darm-Fistel')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[131].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ileumhämorrhagie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ileumblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[132].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ileum Blutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ileumblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[132].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ileum Fistel' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ileumfistel')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[133].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ileumverschluss' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ileumobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[134].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ileumileus' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ileumobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[134].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Unterer Dünndarmdurchbruch' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ileumperforation')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[135].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ileumdurchbruch' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ileumperforation')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[135].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Untere Dünndarmstenose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ileumstenose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[136].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ileumverengung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ileumstenose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[136].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ileumgeschwür' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ileumulkus')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[137].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Darmverschluss' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ileus')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[138].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Intraabdominale Blutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraabdominelle Blutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[139].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Obere Dünndarmfistel' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Jejunumfistel')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[140].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Jejunumhämorrhagie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Jejunumblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[141].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'JejunumiIeus' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Jejunumobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[142].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Jejunumverschluss' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Jejunumobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[142].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ileus des Jejunums' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Jejunumobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[142].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Jejunale Perforation' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Jejunumperforation')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[143].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'oberer Dünndarmdurchbruch' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Jejunumperforation')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[143].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Jejunumverengung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Jejunumstenose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[144].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Jejunumgeschwür' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Jejunumulkus')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[145].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Dünndarmulkus' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Jejunumulkus')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[145].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Dickdarmentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Kolitis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[146].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Labialer Schmerz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Lippenschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[147].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gastrische Hämorrhagie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Magenblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[148].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gastrische Fistel' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Magenfistel')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[149].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Magendurchbruch' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Magenperforation')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[151].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Magenverengung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Magenstenose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[152].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gastritis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Magenschleimhautentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[153].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gastrischer Schmerz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Magenschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[154].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Oberbauchschmerz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Magenschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[154].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Magengeschwür' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Magenulkus')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[155].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Resorptionsstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Malabsorption')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[156].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kurzarmsyndrom' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Malabsorption')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[156].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Mundhöhlenfistel')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[157].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Xerostomie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Mundtrockenheit')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[158].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Übelkeit' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Nausea')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[159].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Brechreiz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Nausea')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[159].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Krampfaderblutung der Speiseröhre' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ösophageale Varizenblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[160].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Speiseröhren- Varizen- Blutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ösophageale Varizenblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[160].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ösophagitis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Speiseröhrenentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[161].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ösophagushämorrhagie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Speisröhrenblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[162].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ösophagusblutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Speisröhrenblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[162].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Speiseröhrenfistel' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ösophagusfistel')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[163].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Speiseröhrennekrose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ösophagusnekrose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[164].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Speiseröhrenverschluss' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ösophagusobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[165].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Speiseröhrenobstruktion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ösophagusobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[165].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Speiseröhrenperforation' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ösophagusperforation')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[166].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Speiseröhrenschmerz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ösophagusschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[167].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Speiseröhrenverengung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ösophagusstenose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[168].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Speiseröhrengeschwür' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ösophagusulkus')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[169].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Mundschleimhautentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Orale Mukositis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[170].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Magenverschluss' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Magenobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[171].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Magenileus' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Magenobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[171].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hämorrhagie des oberen GI'-Traktes' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Obere gastrointestinale Blutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[172].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Blutung, obere gastrointestinale (z. B. \"Streßulkus\")' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Obere gastrointestinale Blutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[172].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Blutung oberer Gastro'-Intestinal'-Trakt' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Obere gastrointestinale Blutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[172].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Verstopfung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Obstipation')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[173].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Mundempfindungsstörungen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Orale Dysästhesie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[174].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Geschmacksstörungen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Orale Dysästhesie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[174].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Mundblutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Orale Blutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[175].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Mundschmerz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Oraler Schmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[176].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Bauchspeicheldrüsenverengung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pankreasgangverengung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[177].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Pankreasgangstenose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pankreasgangverengung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[177].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Bauchspeicheldrüsenblutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pankreasblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[178].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Bauchspeicheldrüsennekrose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pankreasnekrose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[180].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Bauchspeicheldrüsenentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pankreatitis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[181].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Periodontale Zahnfleischerkrankung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Periodontale Erkrankung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[182].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Bauchfellnekrose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Peritoneale Nekrose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[183].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Enddarmentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Proktitis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[184].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Rektumentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Proktitis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[184].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Enddarmschleimhautentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Rektale Schleimhautentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[185].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Rektumentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Rektale Schleimhautentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[185].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Rektale Mukositis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Rektale Schleimhautentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[185].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Enddarmblutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Rektumblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[186].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Rektale Blutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Rektumblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[186].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Enddarmfistel' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Rektumfistel')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[187].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Enddarmnekrose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Rektumnekrose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[188].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Reaktale Nekrose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Rektumnekrose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[188].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Enddarmverschluss' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Rektumobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[189].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Rektumverschluss' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Rektumobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[189].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Enddarmschmerz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Rektumschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[190].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Enddarmperforation' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Rektumperforation')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[191].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Enddarmdurchbruch' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Rektumperforation')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[191].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'rektale Perforation' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Rektumperforation')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[191].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Rektumstenose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Rektumverengung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[192].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Enddarmverengung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Rektumverengung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[192].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Rektaleverengung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Rektumverengung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[192].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ileumulkus' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Rektumgeschwür')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[193].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Enddarmgeschwür' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Rektumgeschwür')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[193].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Retroperitoneale Hämorrhagie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Retroperitoneale Blutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[194].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Dysphagie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Schluckstörung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[195].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Entzündung des Speichelganges' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Speicheldrüsengangentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[197].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Fäkalinkontinenz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Stuhlinkontinenz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[198].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gefühl des Aufgeblähtsein' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Völlegefühl')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[199].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Entzündung des Blinddarms' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Typhlitis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[200].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Entzündung des Zökums' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Typhlitis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[200].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Akute Zökumentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Typhlitis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[200].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Dyspepsie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Verdauungsstörung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[201].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Zahnbildungsstöhrung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Zahnentwicklungsstörung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[202].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gingivaschmerz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Zahnfleischschmerzen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[203].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Zahnkaries')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[204].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Zahnschmerzen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[205].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Zahnverfärbung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[206].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Blinddarmblutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Zökumblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[207].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Zäckumblutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Zökumblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[207].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Caecumblutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Zökumblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[207].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gastrointestinale Erkrankungen  Sonstige, zu spezifizieren')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[208].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Brustschmerz nicht herzbedingt' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Brustschmerz, nicht kardial')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[209].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Irritabilität' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Erregbarkeit')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[210].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Erregung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Erregbarkeit')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[210].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Infusionsflüssigkeitsaustritt' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Extravasat am Infusionsort')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[211].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Blutaustritt aus Gefäß am Infusionsort' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Extravasat am Infusionsort')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[211].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Paravasation' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Extravasat am Infusionsort')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[211].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Paravasat am Infusionsort' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Extravasat am Infusionsort')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[211].designation[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gliederödem' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Extremitätenödem')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[212].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ödem Extremitäten' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Extremitätenödem')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[212].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Erschöpfung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Fatigue')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[213].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Abgeschlagenheit' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Fatigue')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[213].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Müdigkeit' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Fatigue')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[213].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Energielosigkeit' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Fatigue')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[213].designation[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Schwäche' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Fatigue')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[213].designation[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Erhöhte Körpertemperatur' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Fieber')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[214].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gangstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gang-/ Gehbewegungsstörung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[215].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Faziales Ödem' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gesichtsödem')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[216].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gesichtsschwellung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gesichtsödem')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[216].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Fazialisschmerz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gesichtsschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[217].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Nervus facialis Schmerz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gesichtsschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[217].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Facialischmerz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gesichtsschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[217].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Grippesymptome' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Grippeähnliche Symptome')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[218].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Halsschwellung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Halsödem')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[219].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Infusionsbedingte Reaktion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Infusionsbezogene Reaktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[220].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Malaise' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Krankheitsgefühl')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[221].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Unwohlsein' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Krankheitsgefühl')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[221].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Versagen mehrerer Organe' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Multiorganversagen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[222].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'SIDS' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Neugeborenentod')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[223].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ödem, örtliches' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ödem, lokales')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[224].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Flüssigkeitseinlagerung im Körperstamm' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Stammödem')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[225].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Wassereinlagerung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Stammödem')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[225].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Unerwarteter Tod' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Plötzlicher Tod, nicht näher bezeichnet')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[226].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'plötzliches Ableben/ Sterben' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Plötzlicher Tod, nicht näher bezeichnet')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[226].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Reaktion am Injektionsort')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[227].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Qual' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Schmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[228].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Pein' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Schmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[228].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Algesie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Schmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[228].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Frösteln mit Muskelzitten' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Schüttelfrost')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[229].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ableben, n.n.b.' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Tod, n.n.b.')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[230].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Sterben, n.n.b.' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Tod, n.n.b.')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[230].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hypothermie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Unterkühlung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[231].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Allgemeine Störungen und anwendungsbedingten Umstände - Sonstiges, zu spezifizieren')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[232].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gallenfistel' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Biliäre Fistel')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[233].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gallengangfistel' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Biliäre Fistel')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[233].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Cholezystitis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gallenblasenentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[234].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Cholezystische Fistel' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gallenblasenfistel')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[235].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gallenblasenverschluss' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gallenblasenobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[237].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gallenblasendurchbruch' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gallenblasenperforation')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[238].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gallenblasenkoliken' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gallenblasenschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[239].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gallengangdruchbruch' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gallengangperforation')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[240].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gallengangverengung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gallengangstenose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[241].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hepatische Hämorrhagie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Leberblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[242].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hepatische nekrose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Lebernekrose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[243].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hepatischer Schmerz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Leberschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[244].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hepatisches Versagen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Leberversagen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[245].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Pfortadergerinnsel' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pfortaderthrombose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[246].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Pfortaderhochdruck' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Portale Hypertonie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[247].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hepatobiliäre Erkrankungen - Sonstige, zu spezifizieren')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[248].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Überempfindlichkeitsreaktion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Allergische  Reaktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[249].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Allergische Reaktion ohne Schocksymptomatik' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Allergische  Reaktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[249].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Transfusionszwischenfall' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Allergische  Reaktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[249].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Anaphylaktischer Schock' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Anaphylaxie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[250].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Transfusionszwischenfall' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Anaphylaxie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[250].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Autoimmunerkrankung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Autoimmunstörung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[251].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Autoimmunreaktion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Autoimmunstörung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[251].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'AIR' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Autoimmunstörung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[251].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Überempfindlichkeit vom verzögerter Typ' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Serumkrankheit')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[252].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Zytokinfreisetzungssyndrom' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Zytokinsturm')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[253].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Immunsystemstörungen - Sonstige, zu spezifizieren')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[254].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Bauchinfektion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Abdominelle Infektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[255].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'intraabdomineller Abszess' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Abdominelle Infektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[255].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Rektoanale Infektion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Anorektale  Infektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[256].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Wurmfortsatzentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Appendizitis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[257].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Blinddarmentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Appendizitis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[257].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Wurmfortsatzperforation' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Appendizitis, perforierte')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[258].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Perforierte Wurmfortsatzentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Appendizitis, perforierte')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[258].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Arterienentzündung, infektiös' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Arteriitis, infektiöse')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[259].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Infektiöse Arterienentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Arteriitis, infektiöse')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[259].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Infektiöse Augenentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Augeninfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[260].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Beckenentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Beckeninfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[261].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Abszess, intraabdominaler' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Beckeninfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[261].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'pelvine Infektion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Beckeninfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[261].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Zystitis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Blasenentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[262].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Cystitis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Blasenentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[262].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Mammaentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Brustentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[263].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Mastitis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Brustentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[263].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Bronchitis, infektiöse' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Bronchialinfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[264].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Dünndarmentzündung, infektiös' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dünndarminfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[265].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Zwölffingerdarminfektion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Duodenitis, infektiöse')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[266].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Duodenalinfektion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Duodenitis, infektiöse')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[266].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Eileiterentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Eileiterinfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[267].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Endophthalmitis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Entzündung des Augeninneren')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[268].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Infektiöse Enzephalitis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Enzephalitische Infektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[269].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hirninfektion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Enzephalitische Infektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[269].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hirnentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Enzephalitische Infektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[269].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Infektion der Gallenblase' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gallenblaseninfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[270].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gallenblasenentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gallenblaseninfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[270].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Infektion des biliären Traktes' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gallenweginfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[271].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Infektiöse Cholangitis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gallenweginfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[271].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Infektiöse Cervicitis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gebärmutterhalsinfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[272].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Zervixinfektion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gebärmutterhalsinfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[272].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Zervizitis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gebärmutterhalsinfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[272].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Außenohrentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gehörgangentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[273].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gerätebezogene Infektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[274].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Infektiöse Urethritis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Harnröhreninfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[275].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Harnwegsinfekt' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Harnwegsinfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[276].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Infektion der ableitenden Harnwege' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Harnwegsinfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[276].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Harnröhrenentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Harnwegsinfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[276].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Infektiöse Dermatitis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hautinfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[277].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'HautInfektion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hautinfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[277].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Herpes Zoster' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hautinfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[277].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kopfnerventzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hirnnervenentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[278].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hirnnervenausfall' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hirnnervenentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[278].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Encephalomyelitis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hirn-Rückenmark-Infektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[279].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'ZNS Infektion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hirn-Rückenmark-Infektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[279].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Infektion des zentralen Nervensystems' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hirn-Rückenmark-Infektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[279].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Korneale Infektion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hornhautentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[280].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Infektion der oberen Luftwege' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Infektion der oberen Atemwege')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[281].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Infektiöse Herzinnenhautentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Infektiöse Endokarditis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[282].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Endocarditis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Infektiöse Endokarditis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[282].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Infektiöse Darmentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Infektiöse Enterokolitis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[283].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Abszess in einem Drainagekanal' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Katheterbezogene Infektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[284].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Abszess in einem Katheterkanal' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Katheterbezogene Infektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[284].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ostitis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Knochenentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[285].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Osteitis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Knochenentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[285].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Osteomyelitis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Knochenentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[285].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Infektiöse Augenbindehautentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Konjunktivitis, infektiöse')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[286].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hepatische Infektion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Leberinfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[287].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Leber Infektion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Leberinfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[287].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Infektion Skelettmuskulatur' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Infektiöse Myositis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[288].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Skelettmuskelinfektion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Infektiöse Myositis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[288].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Skelettmuskulaturentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Infektiöse Myositis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[288].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Infektiöse Arthritis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gelenkinfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[289].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gelenkentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gelenkinfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[289].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Laryngitis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Kehlkopfentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[290].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Labiale Infektion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Lippeninfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[291].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Infektiöse Pneumonie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Lungeninfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[292].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Infektiöse Lungenentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Lungeninfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[292].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Pneumonie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Lungeninfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[292].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Abszess, intrathorakaler' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Lungeninfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[292].designation[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Infektiöse Lymphdrüsenentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Lymphknoteninfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[293].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Mediastinale Infektion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Mediastinuminfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[294].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Mediastinalinfektion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Mediastinuminfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[294].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Mediastinitis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Mediastinuminfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[294].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Abszess intraabdominaler oder intrathorakaler' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Mediastinuminfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[294].designation[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Infektiöse Splenitis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Milzinfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[296].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Infektiöse Nagelentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Nagelinfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[297].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Otitis media' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Mittelohrentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[298].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Schleimhautinfektion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Mukositis, infektiöse')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[299].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Speiseröhreninfektion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ösophagitis, infektiöse')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[301].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'infektiöse Speiseröhrenentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ösophagitis, infektiöse')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[301].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Pankreatitis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pankreasinfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[302].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Pankreasentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pankreasinfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[302].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Eitriger Hautausschlag' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Papulopustulärer Ausschlag')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[303].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Eitriger Ausschlag' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Papulopustulärer Ausschlag')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[303].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Nagelbettentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Paronychie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[304].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Nagelfalzentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Paronychie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[304].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Penisentzündung, infektiös' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Penisinfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[305].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Infektion eines peripheren Nerven' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Periphere Nerveninfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[306].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Augenhöhleninfektion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Periorbitale Infektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[307].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Infektiöse Peritonitis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Peritoneale Infektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[308].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'peritonealer Abszess' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Peritoneale Infektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[308].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Peritonitis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Peritoneale Infektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[308].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Rachenentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pharyngitis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[309].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Infektiöse Pleuritis (einschließlich Rip'-penfell, Brustfell, Lungenfell, Pleurahöhle)' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pleurainfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[310].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Pleuraempyem' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pleurainfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[310].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'pleuraler Abszess' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pleurainfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[310].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Blutvergiftung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Sepsis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[316].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'septischer Schock' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Sepsis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[316].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Infektiöser Transfusionszwischenfall' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Sepsis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[316].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Nasennebenhöhlenentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Sinusitis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[317].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Infektiöse Skrotumentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Skrotuminfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[318].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hodensackinfektion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Skrotuminfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[318].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'skrotale Infektion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Skrotuminfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[318].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Stomainfektion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Stomatitis, infektiöse')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[319].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Infektion Stomaregion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Stomatitis, infektiöse')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[319].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Infektion im Stomabereich' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Stomatitis, infektiöse')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[319].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Luftröhreninfektion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Tracheitis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[320].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Luftröhrenentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Tracheitis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[320].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Virale Hepatitis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Virushepatitis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[321].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gebärmutterinfektion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Uterusinfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[322].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Infektiöse Vaginitis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vaginale Infektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[323].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Vaginaentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vaginale Infektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[323].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Scheidenentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vaginale Infektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[323].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Vaginalentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vaginale Infektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[323].designation[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Infektiöse Vulvitis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vulvainfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[324].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Vulvaentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vulvainfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[324].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'infektiöse Schamlippenentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vulvainfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[324].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Weichteilgewebeinfektion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Weichgewebeinfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[325].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Abszess, subfaszialer' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Wundinfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[326].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Infektiöse Zahnfleischentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Zahnfleischinfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[327].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Pulpitis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Zahninfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[328].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Blinddarminfektion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Zökalinfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[329].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Zökuminfektion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Zökalinfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[329].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Coecalinfektion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Zökalinfektion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[329].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Infektionen und Infestationen - Sonstige, zu spezifizieren')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[330].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Aortenschädigung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Aortenverletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[331].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Verletzung der Aorta' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Aortenverletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[331].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Aortenschaden' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Arterienverletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[332].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Verletzung einer Arterie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Arterienverletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[332].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Arterienschädigung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Arterienverletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[332].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'dermatitische Recall'-Reaktion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Bestrahlungs-Recall-Reaktion (dermatologisch)')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[333].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Radiologische Recall'-Reaktion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Bestrahlungs-Recall-Reaktion (dermatologisch)')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[333].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Biliäres Anastomosenleck' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Biliäre Anastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[334].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gallenanastomoseninsuffizienz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Biliäre Anastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[334].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Dickdarmanastomosenleck' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dickdarmanastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[335].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kolonanastomoseninsuffizienz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dickdarmanastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[335].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kolonleck' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dickdarmanastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[335].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Dünndarmanastomosenleck' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dünndarmanastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[336].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Duodenalstumpf' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dünndarmanastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[336].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Jejunumstumpf' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dünndarmanastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[336].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ileumstumpfinsuffizienz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dünndarmanastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[336].designation[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Tuba uterina / fallopiiinsuffizienz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Eileiteranastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[337].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Eileiteranastomosenleck' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Eileiteranastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[337].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Eileiterdurchbruch' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Eileiterperforation')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[338].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Eileiterruptur' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Eileiterperforation')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[338].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Tuba uterina/fallopiiperforation' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Eileiterperforation')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[338].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Knochenbruch' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Fraktur')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[339].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Magenanastomoseninsuffizienz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gastrische Anastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[340].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Magenanastomosenleck' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gastrische Anastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[340].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gastrointestinales' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gastrointestinale Anastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[341].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Anastomosenleck' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gastrointestinale Anastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[341].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Komplikation GI- Stomaanlage' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gastrointestinale Stomanekrose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[342].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'GI- satomakomplikation' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gastrointestinale Stomanekrose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[342].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Verengung gastrointestinales Stoma' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gastrointestinale Stomastenose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[343].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'GI- Stomaanlagenverengung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gastrointestinale Stomastenose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[343].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Komplikation beim Gefäßzugang' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gefäßzugangskomplikation')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[344].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Harnblasenanastomosenleck' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Harnblasenanastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[345].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Anastomoseninsuffizienz ableitende Harnwege' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Harnblasenanastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[345].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Handgelenksbruch' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Handgelenksfraktur')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[346].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Harnleiteranastomosenleck' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Harnleiteranastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[347].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ureteranastomoseninsuffizien' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Harnleiteranastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[347].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Urethrales Anastomosenleck' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Harnröhrenanastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[348].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Urethraanastomoseninsuffizienz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Harnröhrenanastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[348].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hüftbruch' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hüftfraktur')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[349].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Schenkelhalsfraktur' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hüftfraktur')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[349].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Anastomoseninsuffizienz Enterostomie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intestinales Stomainsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[350].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Komplikation einer intestinalen Stomaanlage' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intestinales Stomainsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[350].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Vorfall des künstlichen Darmausganges' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intestinaler Stomaprolaps')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[351].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Vorfall / Prolaps intestinale Stomaanlage' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intestinaler Stomaprolaps')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[351].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ausflussbehinderung / Verschluss intestinales Stoma' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intestinale Stomaobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[352].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Stomaausflussbehinderung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intestinale Stomaobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[352].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Intestinale Stomahämorrhagie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intestinale Stomablutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[353].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Stomablutungskomplikation' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intestinale Stomablutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[353].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Intraoperative Schlagaderverletzung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative Arterienverletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[354].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Arterienschädigung, intraoperativ' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative Arterienverletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[354].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Intraoperative Hämorrhagie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative Blutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[355].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Intraoperative kardiale Verletzung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative Herzverletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[356].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'intraoperative Herzschädigung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative Herzverletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[356].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Intraoperative Drüsenverletzung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative endokrine Verletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[357].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'intraoperative Drüsenschädigung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative endokrine Verletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[357].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Intraoperative Darmverletzung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative gastrointestinale Verletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[358].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'intraoperative Darmschädigung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative gastrointestinale Verletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[358].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Intraoperative Brustverletzung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative Mammaverletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[359].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Intraoperative Mammaschädigung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative Mammaverletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[359].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Intraoperative Ohrschädigung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative Ohrverletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[360].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Intraoperative aurikuläre Verletzung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative Ohrverletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[360].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Intraoperative Verletzung der Leber und/oder Gallenwege' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative hepatobiliäre Verletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[361].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'i. o. hepatobiliäre Schädigung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative hepatobiliäre Verletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[361].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Intraoperative Schädigung im Bereich des Kopfes / Halses' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative Kopf/ Halsverletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[362].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Intraoperative Muskel- / Skelettschädigung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative Muskel/ Skelettverletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[363].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'intraoperative Nervenverletzung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative neurologische Verletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[364].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'intraoperative Nervenschädigung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative neurologische Verletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[364].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Intraoperative Augenverletzung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative okuläre Verletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[365].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'i. o. Augenschädigung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative okuläre Verletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[365].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Intraoperative Nierenverletzung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative renale Verletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[366].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'intraoperative Nierenschädigung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative renale Verletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[366].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Intraoperative Schädigung im Bereich des Reproduktionstraktes' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative Reproduktionsorganverletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[367].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'intraoperative Genitalverletzung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative Reproduktionsorganverletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[367].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Intraoperative Schädigung der Respirationsorgane' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative respiratorische Verletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[368].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'intraoperative Atemwegsverletzung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative respiratorische Verletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[368].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Intraoperative Hautschädigung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative Hautverletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[369].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kutane Verletzung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative Hautverletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[369].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kutisverletzung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative Hautverletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[369].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kutisschädigung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative Hautverletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[369].designation[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Intraoperative Milzverletzung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative splenische Verletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[370].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Intraoperative Schädigung der ableitenden Harnwege' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative Verletzung der Harnorgane')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[371].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'i. o. Schädigung des Harntraktes' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative Verletzung der Harnorgane')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[371].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Intraoperative Schädigung einer Vene' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative venöse Verletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[372].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'intraoperative Schädigung venöses System' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intraoperative venöse Verletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[372].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Drosselvenenverletzung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Jugularvenenverletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[373].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'V. jugularisVerletzung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Jugularvenenverletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[373].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Jugularvenenschädigung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Jugularvenenverletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[373].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Halsschlagaderverletzung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Karotisverletzung/Schädigung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[374].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Halsschlagader schädigung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Karotisverletzung/Schädigung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[374].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Carotisverletzung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Karotisverletzung/Schädigung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[374].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Knöchelbruch' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Knöchelfraktur')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[375].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Trachealblutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Luftröhrenblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[376].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Tracheale Obstruktion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Luftröhrenobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[377].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Luftröhrenverschluss' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Luftröhrenobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[377].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Pankreasanastomoseninsuffizienz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pankreatische Anastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[378].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Pankreasanastomosenleck' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pankreatische Anastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[378].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Pharynxanastomoseninsuffizienz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pharyngeale Anastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[379].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Postoperative Hämorrhagie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Postoperative Blutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[380].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Nachblutung, a. n. e.' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Postoperative Blutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[380].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'p. o. Komplikation bei Thoraxprozedur' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Postoperative Thoraxprozedurkomplikation')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[381].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Prellung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Quetschung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[382].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kontusion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Quetschung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[382].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Renales Anastomosenleck' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Renale Anastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[383].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Nierenanastomoseninsuffizienz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Renale Anastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[383].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Rektales Anastomosenleck' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Rektale Anastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[384].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Rektumanastomoseninsuffizienz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Rektale Anastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[384].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Vas deferens Anastomoseninsuffizienz/leck' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Samenleiteranastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[385].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Samenstranganastomosenleck' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Samenstranganastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[386].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Funiculus spermaticusinsuffizienz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Samenstranganastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[386].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Serom')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[387].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Epitheliolyse' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Strahlendermatitis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[388].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kontaktblutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Strahlendermatitis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[388].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Erythem' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Strahlendermatitis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[388].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ösophageale Anastomoseninsuffizienz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Speiseröhrenanastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[389].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Speiseröhrenanastomosenleck' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Speiseröhrenanastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[389].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Stomageschwür' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Stomaulkus')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[390].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gastroenterostomieulcus' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Stomaulkus')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[390].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Fall' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Sturz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[391].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Tracheostomahämorrhagie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Tracheostomablutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[392].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Blutung im Bereich des Tracheostoma' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Tracheostomablutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[392].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Urostomavorfall' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Urostomaprolaps')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[393].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Vorfall künstlicher Harnausgang' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Urostomaprolaps')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[393].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Urostomahämorrhagie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Urostomablutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[394].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Blutung im Bereich des  Urostomas' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Urostomablutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[394].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Harnausgangsinsuffizienz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Urostomaleck')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[395].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Urostomakomplikation' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Urostomaleck')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[395].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Urostomabehinderung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Urostomaleck')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[395].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Urostomabehinderung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Urostomaobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[396].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Urostomaverschluss' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Urostomaobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[396].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Urostomablockade' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Urostomaobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[396].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Harnausgangsinsuffizienz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Urostomastenose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[397].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Urostomaverengung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Urostomastenose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[397].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Urostomaabflusskomplikation' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Urostomastenose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[397].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Anastomosenleck des Uterus' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Uterine(s) Anastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[398].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Uterusanastomoseninsuffizienz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Uterine(s) Anastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[398].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Uterusdurchbruch' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Uterine Perforation')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[399].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Uterusruptur' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Uterine Perforation')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[399].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Uterusperforation' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Uterine Perforation')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[399].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Vaginaanastomoseninsuffizienz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vaginale(s) Anastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[400].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Vaginales Anastomosenleck' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vaginale(s) Anastomoseninsuffizienz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[400].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Oberen Hohlvenenschädigung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vena cava superior Verletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[401].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Vena cavasuperior Verletzung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vena cava superior Verletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[401].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Venenschädigung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Venenverletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[402].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Venenschaden' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Venenverletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[402].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Thermische Schädigung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Verbrennung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[403].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Untere Hohlvenenverletzung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vena cava inferior Verletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[404].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Vena Cava inferior Schädigung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vena cava inferior Verletzung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[404].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Spinale Fraktur' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Wirbelsäulenfraktur')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[405].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Wundheilungsstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Wundkomplikation')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[406].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Abszess, subfaszial' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Wundkomplikation')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[406].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Auseinanderweichen der Wundränder' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Wunddehiszenz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[407].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Platzbauch' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Wunddehiszenz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[407].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Nahtinsuffizienz, a. n. e.' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Wunddehiszenz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[407].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Wundheilungsstörung, s. c.' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Wunddehiszenz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[407].designation[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Verletzung, Vergiftung und prozedurale Komplikationen - Sonstige, zu spezifizieren')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[408].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Corticotropin' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('ACTH (Corticotropin) im Blut erniedrigt')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[409].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Adrenocorticotropin' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('ACTH (Corticotropin) im Blut erniedrigt')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[409].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Adrenocorticotropes Hormon' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('ACTH (Corticotropin) im Blut erniedrigt')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[409].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'ACTH erniedrigt' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('ACTH (Corticotropin) im Blut erniedrigt')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[409].designation[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'PTT' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Aktivierte partielle Thromboplastinzeit verlängert')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[410].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Partielle Thromboplastinzeit verlängert' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Aktivierte partielle Thromboplastinzeit verlängert')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[410].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'ALAT' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Alanin-Aminotransferase erhöht')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[411].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'ALT' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Alanin-Aminotransferase erhöht')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[411].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'GPT erhöht' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Alanin-Aminotransferase erhöht')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[411].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'AP erhöht' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Alkalische Phosphatase erhöht')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[412].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'AST, GOT erhöht' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Aspartat-Aminotransferase erhöht')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[413].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'ADH Vasopression VP' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Antidiuretisches Hormon im Blut außerhalb Norm')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[414].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Arginin Vasopressin  AVP erhöht' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Antidiuretisches Hormon im Blut außerhalb Norm')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[414].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hyperbilirubinämie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Bilirubin im Blut erhöht')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[415].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('CD4-Lymphozyten verringert')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[416].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Cholesterin erhöht' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Cholesterin hoch')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[417].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'CPK hoch' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Creatinphosphokinase erhöht')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[418].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Creatinkinase erhöht' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Creatinphosphokinase erhöht')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[418].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ejektionsfraktion verringert' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ejektionsfraktion herabgesetzt')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[419].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'EKG: QT Dauer verlängert' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('EKG: korrigiertes QT Intervall verlängert')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[420].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Forcierte Vitalkapazität verringert' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('FEV1 erniedrigt')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[421].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Fibrinogen verringert')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[422].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'GGT' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gamma-Glutamyltransferase erhöht')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[423].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'γ-Glutamyltransferase' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gamma-Glutamyltransferase erhöht')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[423].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gamma-GT' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gamma-Glutamyltransferase erhöht')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[423].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'γ-Glutamyltranspeptidase' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gamma-Glutamyltransferase erhöht')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[423].designation[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'γ-GTP erhöht' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gamma-Glutamyltransferase erhöht')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[423].designation[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'γ-GTP' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gamma-Glutamyltransferase erhöht')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[423].designation[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Leukozytopenie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gesamt-Leukozyten verringert')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[424].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Weiße Blutkörperchenverringerung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gesamt-Leukozyten verringert')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[424].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Leukopenie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gesamt-Leukozyten verringert')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[424].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Leukozytenabfall' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gesamt-Leukozyten verringert')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[424].designation[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Körpergewichterniedrigung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gewichtsverlust')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[425].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Körpergewichtserhöhung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gewichtszunahme')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[426].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Luteinisierendes Hormon LH' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gonadotropin im Blut anormal')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[427].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Follikelstimulierendes Hormon FSH' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gonadotropin im Blut anormal')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[427].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Humanes Choriongonadotropin hCG' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gonadotropin im Blut anormal')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[427].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Haptoglobin verringert')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[428].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hb erhöht' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hämoglobin erhöht')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[429].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Kardiales Troponin I erhöht')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[430].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Kardiales Troponin T erhöht')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[431].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Creatinin erhöht' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Kreatinin erhöht')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[432].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Lipoproteinlipase LPL, LP' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Lipase erhöht')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[433].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Pankreaslipase' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Lipase erhöht')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[433].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Steapsin erhöht' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Lipase erhöht')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[433].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Lymphozytopenie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[434].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Lymphozytose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[435].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Leukozytopenie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Neutrophile Granulozyten verringert')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[436].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Leukopenie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Neutrophile Granulozyten verringert')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[436].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Pankreas Amylase' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pankreasenzym verringert')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[437].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Pankreaslipase herabgesetzt' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pankreasenzym verringert')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[437].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Prolaktin' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Prolaktin im Blut außerhalb Norm')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[438].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'PRL Laktotropes Hormon' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Prolaktin im Blut außerhalb Norm')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[438].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'LTH Lactotropin' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Prolaktin im Blut außerhalb Norm')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[438].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Laktotropin außerhalb der Norm' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Prolaktin im Blut außerhalb Norm')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[438].designation[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pulmonale Transferkapazität für Kohlenmonoxid verringert')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[439].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'INR erhöht' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Prothrombinzeit erhöht')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[440].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'α'-Amylase' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Serum Amylase erhöht')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[441].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'β'-Amylase' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Serum Amylase erhöht')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[441].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'γ'-Amylase erhöht' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Serum Amylase erhöht')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[441].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Thrombopenie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Thrombozytopenie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[442].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Blutplättchen erniedrigt' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Thrombozytopenie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[442].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Thrombozytenabfall' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Thrombozytopenie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[442].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Urinausscheidung verringert')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[443].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Maximales Atemvolumen außerhalb der Norm' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vitalkapazität anormal')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[444].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Vitalkapazität außerhalb der Norm' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vitalkapazität anormal')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[444].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'growth hormone außerhalb der Norm' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Wachstumshormon außerhalb Norm')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[445].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'GH' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Wachstumshormon außerhalb Norm')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[445].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Sonstige Laborwerte' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Untersuchungen - Sonstige, zu spezifizieren')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[446].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Fettleibigkeit' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Adipositas')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[447].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Übergewicht' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Adipositas')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[447].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Obesitas' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Adipositas')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[447].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Alkoholunverträglichkeit' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Alkoholintoleranz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[448].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Blut pH Erhöhung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Alkalose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[449].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Störung des Flüssigkeits, Elektrolyt und Säurebasenhaushaltes' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Alkalose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[449].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Magersuch' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Anorexie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[450].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Störung des Flüssigkeits-, Elektrolyt- und Säurebasenhaushaltes' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Azidose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[451].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Exsikkose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dehydrierung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[452].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Störung des Flüssigkeits-, Elektrolyt- und Säurebasenhaushaltes, Exsiccose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dehydrierung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[452].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Erhöhter Eisengehalt' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Eisenüberlastung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[453].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hypersiderinämie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Eisenüberlastung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[453].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gewebeeisenerhöhung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Eisenüberlastung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[453].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Glukosestoffwechselstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Glucoseintoleranz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[454].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Zuckerintoleranz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Glucoseintoleranz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[454].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Störung des Flüssigkeits-, Elektrolyt- und Säurebasenhaushaltes Hypercalcämie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hyperkalzämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[455].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hyperglykämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[456].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kaliumerhöhung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hyperkaliämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[457].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Magnesiumerhöhung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypermagnesiämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[458].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Natriumerhöhung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypernatriämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[459].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Neutralblutfetterhöhung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypertriglyzeridämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[460].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Triglyzeriderhöhung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypertriglyzeridämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[460].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Triacylglycerol-, TAG-, Tri- Oacylglycerol Erhöhung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypertriglyzeridämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[460].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Harnsäureerhöhung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hyperurikämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[461].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Albuminerniedrigung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypoalbuminämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[462].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Albuminmangel' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypoalbuminämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[462].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kalziumerniedrigung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypokalzämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[463].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'niedriges Calcium' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypokalzämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[463].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Calciummangel' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypokalzämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[463].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Blutzuckererniedrigung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypoglykämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[464].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Unterzuckerrung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypoglykämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[464].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Niedriger Blutzucker' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypoglykämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[464].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Störung des Flüssigkeits-, Elektrolyt- und Säurebasenhaushaltes' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypokaliämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[465].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Niedriges Kalium' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypokaliämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[465].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Störung des Flüssigkeits-, Elektrolyt- und Säurebasenhaushaltes' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypomagnesiämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[466].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Niedriges Magnesium' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypomagnesiämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[466].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Störung des Flüssigkeits-, Elektrolyt- und Säurebasenhaushaltes' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hyponatriämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[467].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Niedriges Natrium' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hyponatriämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[467].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Störung des Flüssigkeits-, Elektrolyt- und Säurebasenhaushaltes' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypophosphatämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[468].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Niedrige Blutphosphate' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypophosphatämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[468].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'tumor lysis syndrome (engl.)' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Tumorlyse Syndrom')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[469].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Stoffwechsel und Ernährung - Sonstiges, zu spezifizieren')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[470].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Abdominale Weichteilnekrose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Abdominale Weichgewebenekrose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[471].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Absterben von Bauchweichgewebe' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Abdominale Weichgewebenekrose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[471].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gelenkschmerz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Arthralgie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[472].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gelenkentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Arthritis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[473].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Avaskuläre Knochennekrose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Avaskuläre Nekrose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[474].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Fibrose des tiefen Bindegewebes' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Bindegewebefibrose, tiefe')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[475].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Tiefe Bindegewebsnekrose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Bindegewebefibrose, tiefe')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[475].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Thoraxwandschmerzen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Brustwandschmerzen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[476].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Exostose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[477].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Flankenschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[478].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Allgemeine Muskelparese' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Generelle Muskelschwäche')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[479].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Flüssigkeitserguss eines Gelenkes' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gelenkerguss')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[480].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Übermäßige Gelenkflüssigkeit' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gelenkerguss')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[480].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gesäßschmerzen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[481].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Halsschmerzen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[482].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Bindegewebenekrose im Nackenbereich' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Halsweichgewebenekrose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[483].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ossäre Schmerzen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Knochenschmerzen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[484].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Dorsal konvexe Wirbelsäulenverkrümmung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Kyphose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[485].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ventral konvexe Wirbelsäulenverkrümmung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Lordose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[486].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hemiparese linksseitig' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Muskelschwäche, linksseitig')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[487].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Muskelschwäche untere Gliedmaßen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Muskelschwäche, untere Extremität')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[488].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hemiparese rechtsseitig' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Muskelschwäche, rechtsseitig')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[489].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Muskelschwäche Körperstamm' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Muskelschwäche, Rumpf')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[490].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Muskelschwäche obere Gliedmaßen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Muskelschwäche, obere Extremität')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[491].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Deformierung Bewegungsapparat' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Muskel-Skelett-Deformität')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[492].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Muskelschmerz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Myalgie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[493].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Muskelentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Myositis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[494].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kieferknochennekrose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Osteonekrose Kiefer')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[495].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kiefernekrose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Osteonekrose Kiefer')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[495].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Knochenschwund' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Osteoporose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[496].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Weichgewebenekrose des Beckens' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pelvine Weichgewebenekrose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[497].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Weichgewebenekrose Becken' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pelvine Weichgewebenekrose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[497].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Weichteilgewebenekrose des Beckens' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pelvine Weichgewebenekrose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[497].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'low back pain' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Rückenschmerzen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[498].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Lumbago' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Rückenschmerzen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[498].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hexenschuss' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Rückenschmerzen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[498].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gliederschmerz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Schmerz in Extremität')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[499].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Seitliche Rückgratverkrümmung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Skoliose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[500].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Eingeschränkte Mundöffnung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Trismus')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[501].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kieferklemme' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Trismus')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[501].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kiefersperre' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Trismus')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[501].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Eingeschränkter Bewegungsbereich im Gelenk' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Verminderung des Bewegungsumfangs eines Gelenkes')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[502].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Eingeschränkter Bewegungsbereich der Halswirbelsäule' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Verminderung des Bewegungsumfangs der HWS')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[503].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Eingeschränkter Bewegungsbereich in Lendenwirbelsäule' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Verminderung des Bewegungsumfanges der LWS')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[504].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Wachstumsstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Wachstumshemmung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[505].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Wachstumsunterdrückung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Wachstumshemmung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[505].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kopf- Weichgewebenekrose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Weichgewebenekrose, Kopf(-bereich)')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[506].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Weichgewebenekrose untere Gliedmaße' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Weichgewebenekrose, untere Extremität')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[507].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Weichteilnekrose der unteren Extremität' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Weichgewebenekrose, untere Extremität')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[507].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Weichgewebenekrose obere Gliedmaßen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Weichgewebenekrose, obere Extremität')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[508].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Weichteilnekrose der oberen Extremität' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Weichgewebenekrose, obere Extremität')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[508].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Oberflächliche Weichgewebsnekrose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Weichgewebefibrose, oberflächliche')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[509].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ungleiche Gliedmaßenlänge')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[510].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Bewegungsapparat und Bindegewebe - Sonstiges, zu spezifizieren')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[511].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Leukämie, verursacht durch onkologische Chemotherapie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Leukämie, sekundär durch onkologische Chemotherapie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[512].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Therapiebedingte maligne Zweiterkrankung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Sekundäre Malignität, behandlungsassoziiert')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[514].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Bösartige Zweiterkrankung aufgrund Intervention' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Sekundäre Malignität, behandlungsassoziiert')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[514].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Tumorschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[515].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Neoplasien, gutartig, bösartig und/oder unbekannten Verhaltens - Sonstige, zu spezifizieren')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[516].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Nervus abducens Erkrankung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Abducens Störung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[517].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hirnnervenausfall' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Abducens Störung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[517].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Erkrankung im Nervus abducens' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Abducens Störung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[517].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Nervus accessorius Störung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Accessorius Störung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[518].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Accessorius Krankheit' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Accessorius Störung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[518].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'XI. Kopfnervausfall' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Accessorius Störung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[518].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hörnerverkrankung, o. n. A.' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Akustikus Störung o. n. A')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[519].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Akustikus'-Nerv'-Erkrankung,' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Akustikus Störung o. n. A')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[519].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '8. Hirnnervenausfall' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Akustikus Störung o. n. A')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[519].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Erkrankung des Gehörnerv' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Akustikus Störung o. n. A')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[519].designation[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'N. acusticus Erkrankung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Akustikus Störung o. n. A')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[519].designation[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Psychomotorische Unruhe' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Akathisie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[520].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gedächtnisverlust' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Amnesie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[521].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Erinnerungsstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Amnesie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[521].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Epilepsie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Krampfanfall')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[522].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'epileptischer Anfall' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Krampfanfall')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[522].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Anfall' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Krampfanfall')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[522].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Stimmverlust' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Aphonie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[523].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Entzündung der Spinnenhaut des ZNS' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Arachnoiditis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[524].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gangunsicherheit' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ataxie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[525].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Fallneigung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ataxie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[525].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Koordinationsstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ataxie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[525].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Störung der Bewegungskoordination' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ataxie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[525].designation[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Funktionsbeeinträchtigung des Armplexus' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Brachiale Plexopathie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[526].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Sprechstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dysarthrie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[527].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Sprachstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dysarthrie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[527].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Berührungsmissempfindung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dysästhesie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[528].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Störung Sensibilität' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dysästhesie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[528].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'sensorische Störung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dysästhesie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[528].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Minderung der Sprachausdrucksfähigkeit' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dysphasie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[529].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Minderung der Sprachfähigkeit' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dysphasie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[529].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Enzephalopathie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[530].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Extrapyramidale Erkrankung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Extrapyramidale Störungen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[531].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gedächtnisschwäche')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[532].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Dygeusie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Geschmacksstörung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[533].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ageusie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Geschmacksstörung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[533].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Schmekstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Geschmacksstörung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[533].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Fazialisparese' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gesichtsmuskelschwäche')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[534].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gesichtsnervausfall' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gesichtsmuskelschwäche')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[534].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Fazialisparese' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gesichtsnervstörung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[535].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gesichtsnervausfall' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gesichtsnervstörung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[535].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Fazialislähmung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gesichtsnervstörung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[535].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Nervus glossopharyngeussstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Glossopharyngeus Störung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[536].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hirnnervenausfall' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Glossopharyngeus Störung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[536].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hirndruck' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hirnödem')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[537].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Wasserkopf' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hydozephalus')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[538].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Exzessives Schlafbedürfnis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypersomnie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[539].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Tagesschlafbedürfnis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypersomnie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[539].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Nervus hypoglossus Störung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypoglossus Störung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[540].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Störung des Unterzungennerven' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypoglossus Störung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[540].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Zerebrale Blutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intrakranielle Blutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[541].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hirnblutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intrakranielle Blutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[541].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Schädelblutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Intrakranielle Blutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[541].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kognitive Störung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Kognitionsstörung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[542].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Desorientiertheit' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Kognitionsstörung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[542].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Wahrnehmungsstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Kognitionsstörung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[542].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Konzentrationsschwäche')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[543].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Cephalgie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Kopfschmerzen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[544].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Lethargie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[545].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Krankhafte Veränderung der weißen Hirnsubstanz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Leukenzephalopathie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[546].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Nichtentzündliche nekrotische Herde in der weißen Hirnsubstanz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Leukenzephalopathie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[546].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Meningismus')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[547].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Rückenmarksentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Myelitis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[548].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Sinusschmerz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Nasennebenhöhlenschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[549].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Stirnhöhlenschmerz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Nasennebenhöhlenschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[549].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Nekrose im Zentralnervensystem' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Nekrose des Zentralnervensystems')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[550].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'ZNS- Nekrose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Nekrose des Zentralnervensystems')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[550].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Nervenschmerz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Neuralgie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[551].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Unkontrollierte Augenbewegungen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Nystagmus')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[552].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Nervus oculomotorius Störung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Oculomotorius Störung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[553].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hirnnervenausfall, Okulomotoriuserkrankung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Oculomotorius Störung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[553].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Nervus olfactorius Störung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Olfactorius Störung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[554].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hirnnervenausfall' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Olfactorius Störung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[554].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Okulomotoriuserkrankung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Olfactorius Störung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[554].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Motorische Neuropathie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Periphere motorische Neuropathie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[555].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Periphere Parese' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Periphere motorische Neuropathie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[555].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Empfindungsstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Periphere sensorische Neuropathie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[556].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Sensibilitätsstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Periphere sensorische Neuropathie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[556].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Phantomschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[557].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Zustand von Ohnmacht' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Präsynkope')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[558].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pyramidenbahn-Syndrom')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[559].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Radikulopathie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Radikulitis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[560].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Wurzelsyndrom' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Radikulitis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[560].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Rekurrenslähmung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Recurrensparese')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[561].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Lähmung des Nervus laryngeusrecur' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Recurrensparese')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[561].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Rekurrensparese' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Recurrensparese')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[561].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Posteriores reversibles enzephalopathie-Syndrom' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Reversibles posteriores Leukenzephalopathie-Syndrom (RPLS)')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[562].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Somnolenz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Schläfrigkeit')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[563].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Apoplex' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Schlaganfall')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[564].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Zerebrovaskulären Insult' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Schlaganfall')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[564].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'apoplexie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Schlaganfall')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[564].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hinrnschlag' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Schlaganfall')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[564].designation[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Cerebrovaskuläres Ereignis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Schlaganfall')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[564].designation[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Apoplektischer Insult' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Schlaganfall')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[564].designation[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Benommenheit' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Schwindel')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[565].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Parästhesie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Sensibilitätsstörung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[566].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Spastizität' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Spastische Lähmung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[567].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ohnmacht' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Synkope')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[568].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kollaps' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Synkope')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[568].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Vorübergehende Durchblutungsstörung des Gehirns' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Transistorische ischämische Attacke (TIA)')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[569].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'TIA' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Transistorische ischämische Attacke (TIA)')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[569].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'transitorische ischämische Attacke' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Transistorische ischämische Attacke (TIA)')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[569].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'RIND' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Transistorische ischämische Attacke (TIA)')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[569].designation[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'reversibles ischämisches neurologisches Defizit' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Transistorische ischämische Attacke (TIA)')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[569].designation[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Tremor')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[570].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Trigeminuserkrankung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Trigeminus Störung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[571].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Nervus trigeminus Störung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Trigeminus Störung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[571].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Nervus trochlearis Störung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Trochlearis Störung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[572].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Störung des schrägen, oberen Augenmuskels' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Trochlearis Störung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[572].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Unwillkürliche Bewegungen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[573].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Vagusnerv Erkrankung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vagus Störung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[574].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hirnnervenausfall' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vagus Störung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[574].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Nervus vagus Störung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vagus Störung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[574].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kurze Bewusstlosigkeit' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vasovakale Synkope')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[575].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Boygroup'-Syndrom' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vasovakale Synkope')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[575].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Vasovagale Reaktion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vasovakale Synkope')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[575].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Verringerter Bewusstseinszustand' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Verminderter Bewusstseinszustand')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[576].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'reduzierter Bewusstseinszustand' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Verminderter Bewusstseinszustand')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[576].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'erniedrigter Bewusstseinszustand' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Verminderter Bewusstseinszustand')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[576].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Verlust von Hirn'-/ Rückenmarksflüssigkeit' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Zerbrospinales Flüssigkeitsleck')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[577].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Zerebrovaskuläre Mangeldurchblutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Zerebrovaskuläre Ischämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[578].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hirnminderdurchblutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Zerebrovaskuläre Ischämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[578].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hemiparese' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Erkrankungen des Nervensystems - Sonstige  zu spezifizieren')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[579].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Fetaltod' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Fetaler Tod')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[580].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Todgeburt' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Fetaler Tod')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[580].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Fötaler Tod' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Fetaler Tod')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[580].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Fetale Retardation' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Fetale Wachstumsverzögerung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[581].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'fetale Verzögerung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Fetale Wachstumsverzögerung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[581].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Prämature Geburt' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Frühgeburt')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[582].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ungewollte Schwangerschaft' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Unbeabsichtigte Schwangerschaft')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[583].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Schwangerschaft, Kindbett, perinatale Erkrankungen - Sonstiges, zu spezifizieren')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[584].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Unruhe' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Agitiertheit')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[585].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Aufgeregtheit' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Agitiertheit')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[585].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Innere Unruhe' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Angstgefühl')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[586].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Andauernde Furcht' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Angstgefühl')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[586].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Beklemmung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Angstgefühl')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[586].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Orgasmusunfähigkeit' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Anorgasmie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[587].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Wahn' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Delirium')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[588].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Alkoholentzugspsychose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Delirium')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[588].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Entzugspsychosen, andere' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Delirium')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[588].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Drogenentzugspsychose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Delirium')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[588].designation[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hirnorganisches Psychosyndrom' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Delirium')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[588].designation[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'HOP (z.B. \"Durchgangssyndrom\")' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Delirium')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[588].designation[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'kurzzeitiges Delir' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Delirium')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[588].designation[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Schwere Niedergeschlagenheit' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Depression')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[589].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'tiefe Verstimmung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Depression')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[589].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Schwermut' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Depression')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[589].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hochstimmung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Euphorie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[590].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Wahnvorstellungen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Halluzinationen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[591].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Libido, vermindert')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[592].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Libido, gesteigert')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[593].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Wahnsinn' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Manie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[594].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'manische Episode' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Manie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[594].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Verzögerter Höhepunkt' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Orgasmus, verzögert')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[595].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'personality change' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Persönlichkeitsveränderung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[596].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'verzögerter Klimax' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Persönlichkeitsveränderung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[596].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Persönlichkeitswechsel' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Persönlichkeitsveränderung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[596].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Bewusstseinsspaltung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Psychose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[597].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Psychotische Störung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Psychose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[597].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Schlafstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Schlaflosigkeit')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[598].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Insomnia' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Schlaflosigkeit')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[598].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Suizidvorstellungen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Suizidgedanken')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[599].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Selbstmordversuch' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Suizidversuche')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[600].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Selbsttötungsversuch' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Suizidversuche')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[600].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Freitodversuch' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Suizidversuche')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[600].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ruhelosigkeit' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Unruhe')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[601].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Desorientiertheit' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Verwirrung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[602].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Konfusion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Verwirrung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[602].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Drogenentzugspsychose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Wahnvorstellungen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[603].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Psychiatrische Störungen - Sonstige, zu spezifizieren')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[604].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Akutes renales Versagen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Akutes Nierenversagen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[605].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Akute Niereninsufizienz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Akutes Nierenversagen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[605].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Akuter Nierenfunktionsverlust' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Akutes Nierenversagen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[605].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Abakterielle Harnblasenentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Blasenentzündung, nichtinfektiöse')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[606].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'abakterielle Zystitis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Blasenentzündung, nichtinfektiöse')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[606].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Harnblasenspassmus' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Blasenkrampf')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[607].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Schmerzhafter Harndrang' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Blasenkrampf')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[607].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Blasenperforation')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[608].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Chronische Niereninsuffizienz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Chronische Nierenerkrankung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[609].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'chronisches Nierenversagen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Chronische Nierenerkrankung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[609].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Blutiger Urin' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hämaturie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[610].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Blutharnen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hämaturie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[610].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Blut im Urin' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hämaturie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[610].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hämoglobinurie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[611].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Urindrang' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Harndrang,  vermehrter')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[612].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Miktionsdran' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Harndrang,  vermehrter')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[612].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Pollakisurie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Harndrang,  vermehrter')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[612].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Polyurie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Harndrang,  vermehrter')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[612].designation[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Nykturei' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Harndrang,  vermehrter')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[612].designation[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Urindiskoloration' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Harnfarbveränderung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[613].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Urinverfärbung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Harnfarbveränderung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[613].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Veränderung der Harnfarbe' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Harnfarbveränderung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[613].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Harnretention' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Harnstau')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[614].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Urinretention' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Harnstau')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[614].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Algurie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Harnwegsschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[615].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Blasenverschluss' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Harnwegsverschluss')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[616].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Harnwegsobstruktion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Harnwegsverschluss')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[616].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Harnblasenschwäche' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Inkontinenz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[617].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Renale Hämorrhagie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Nierenblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[618].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Nierenkolik')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[619].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Calculus renalis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Nierenstein')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[620].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Harnstein' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Nierenstein')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[620].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Nierenbeckenstein' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Nierenstein')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[620].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'häufiges Wasser lassen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pollakisurie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[621].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Proteinurie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[622].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Harnfistel' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Urinfistel')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[623].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Blasenfistel' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Urinfistel')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[623].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Störungen der Nieren-und Harnorganen - Sonstige, zu spezifizieren')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[624].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Azoospermie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[625].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Beckenbodenmuskelschwäche')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[626].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Beckenschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[627].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Mammaatrophie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Brustatrophie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[628].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Brustschwund' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Brustatrophie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[628].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Atrophie der Mamma' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Brustatrophie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[628].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Mammaschmerz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Brustschmerzen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[629].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Perinealer Schmerz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dammschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[631].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Perineumschmerz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dammschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[631].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Menstruationsbeschwerden' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dysmenorrhoe')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[632].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Dysmenorrhö' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dysmenorrhoe')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[632].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Beschwerden beim Geschlechtsverkehr' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dyspareunie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[633].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Schmerzen beim Geschlechtsverkehr' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dyspareunie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[633].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Eierstockeinriss' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Eierstockruptur')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[634].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'ovarielle Ruptur' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Eierstockruptur')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[634].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ovarrptur' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Eierstockruptur')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[634].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ovarialblutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Eierstockblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[635].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ovarielle Blutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Eierstockblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[635].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Eileiterverschluss' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Eileiterobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[636].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Eileiterverenung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Eileiterstenose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[637].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Samenergusssstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ejakulationsstörung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[638].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Erektile Dysfunktion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Erektionsstörung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[639].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Erektionsschwierigkeiten' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Erektionsstörung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[639].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Potenzstörungen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Erektionsstörung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[639].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Erworbene Verweiblichung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Feminisierung, erworbene')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[640].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Genitale Schwellung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Genitales Ödem')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[641].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Weibliche Genitalfistel' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Genitalfistel, weibliches Geschlecht')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[642].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Vergrößerung der männlichen Brustdrüsen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Gynäkomastie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[643].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Eileiterblutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hämatosalpinx')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[644].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Eileiterblutstau' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hämatosalpinx')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[644].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Testeshämorrhagie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hodenblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[645].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hodenhämorrhagie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hodenblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[645].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'testikuläre Blutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hodenblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[645].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'testikuläre Hämorrhagie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hodenblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[645].designation[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hodenfunktionsstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hodenerkrankung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[646].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Testesschmerz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hodenschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[647].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'testikulärer Schmerz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hodenschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[647].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Störung der Milchproduktion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Laktationsstörung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[648].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Verfrühtes Klimakterium' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Menopause, verfrühte')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[649].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Climacterium präcox' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Menopause, verfrühte')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[649].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'vorzeitige Wechseljahre' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Menopause, verfrühte')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[649].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Schwere Menstruationsblutungen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Menorrhagie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[650].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Andauernde Menstruation' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Menorrhagie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[650].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'abnormale uterine Blutung (AUB)' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Menorrhagie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[650].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Menstruation, unregelmäßige')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[651].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Verminderte Spermienzahl' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Oligospermie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[652].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Mittelschmerz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ovulationsschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[653].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Peniler Schmerz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Penisschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[654].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Blutung der Vorsteherdrüse' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Prostatablutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[655].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Prostatahämorrhagie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Prostatablutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[655].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Prostataverschluss' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Prostataobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[656].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Behinderung (des Wasserlassens durch die Prostata)' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Prostataobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[656].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Prostataschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[657].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Corda spermatica Blutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Samenstrangblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[658].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Samenstranghämorrhagie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Samenstrangblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[658].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Samenstrangverschluss' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Samenstrangobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[659].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hodensackschermz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Skrotalschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[660].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gebärmutterfistel' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Uterusfistel')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[661].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'uterinale Fistel' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Uterusfistel')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[661].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Uterushämorrhagie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Uterusblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[662].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'uterine Blutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Uterusblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[662].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'uterine Hämorrhagie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Uterusblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[662].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gebärmutterverschluss' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Uterusobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[663].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Uterus Verschluss' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Uterusobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[663].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gebärmutterschmerz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Uterusschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[664].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'uteriner Schmerz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Uterusschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[664].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Vaginale Sekretion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vaginaler Ausfluss')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[665].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Scheidensekretion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vaginaler Ausfluss')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[665].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Scheidenausfluss' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vaginaler Ausfluss')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[665].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Vaginalhämorrhagie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vaginalblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[667].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Scheidenblutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vaginalblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[667].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Scheidenentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vaginalentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[668].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Vaginale Fistel' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vaginafistel')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[669].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Scheidenfistel' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vaginafistel')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[669].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Scheidenperforation' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vaginalperforation')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[670].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Scheidenschmerz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vaginalschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[671].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'vaginaler Schmerz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vaginalschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[671].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Scheidenverengung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vaginalstenose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[672].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Vaginalverenung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vaginalstenose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[672].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Scheidenverschlusss' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vaginalverschluss')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[673].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Scheidenkrampf' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vaginismus')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[674].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Scheidenspasmen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vaginismus')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[674].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Vaginalspasmen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vaginismus')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[674].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Störungen der Fortpflanzungsorgane und der Brust - Sonstige, zu spezifizieren')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[675].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Allergische Rhinitis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[676].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Aspiration')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[677].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Sekundäre Atelektase' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Atelektasen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[678].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Lungenkollaps' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Atelektasen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[678].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Akutes respiratorisches Distress Syndrom' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Atemnotsyndrom des Erwachsenen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[679].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'ARDS' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Atemnotsyndrom des Erwachsenen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[679].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'respiratorisches Distress Syndrom RDS' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Atemnotsyndrom des Erwachsenen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[679].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Schocklunge' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Atemnotsyndrom des Erwachsenen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[679].designation[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'adultes respiratorisches Distress Syndrom' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Atemnotsyndrom des Erwachsenen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[679].designation[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Apnoe' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Atemstillstand')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[680].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Interstielle Pneumonie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Atypische Pneumonie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[681].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Atypische Lungenentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Atypische Pneumonie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[681].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Bronchusstumpfinsuffizienz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Bronchialfistel')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[682].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Bronchialverschluss' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Bronchiale Obstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[683].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Bronchialverengung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Bronchialstenose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[684].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Bronchus- Pleura- Fistel' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Bronchopleurale Fistel')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[685].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Bronchialblutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Bronchopulmonale Blutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[686].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Bronchialhämorrhagie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Bronchopulmonale Blutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[686].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Bronchialkrampf' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Bronchospasmus')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[687].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Lymphe in der Pleurahöhle' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Chylothorax')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[688].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'pleurale Lymphansammlung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Chylothorax')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[688].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'pleuraler Lympherguss' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Chylothorax')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[688].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kurzatmigkeit' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dyspnoe')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[689].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Atemnot' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Dyspnoe')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[689].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Nasenbluten' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Epistaxis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[690].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Pfeifen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Giemen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[691].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Haslschmerzen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Halsentzündung, Rachenentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[692].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Halsentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Halsentzündung, Rachenentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[692].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Rachenentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Halsentzündung, Rachenentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[692].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Halsbeschwerden' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Halsentzündung, Rachenentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[692].designation[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Rachenbeschwerden' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Halsentzündung, Rachenentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[692].designation[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Heiserkeit')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[693].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Husten')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[694].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Sauerstoffmangel' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypoxie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[695].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Larynxentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Laryngitis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[696].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kehlkopfentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Laryngitis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[696].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Larynx'-Pharynx'-Dysästhesie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Laryngopharyngeale Dysästhesie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[697].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Larynxdysästhesie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Laryngopharyngeale Dysästhesie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[697].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Stimmlippenkrampf' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Laryngospasmus')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[698].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kehlkopfblutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Larynxblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[699].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kehlkopffistel' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Larynxfistel')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[700].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kehlkopfödem' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Larynxödem')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[701].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Laryngeale Obstruktion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Larynxobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[702].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kehlkopfhindernis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Larynxobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[702].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kehlkopfobstruktion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Larynxobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[702].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Larynxverschluss' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Larynxobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[702].designation[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kehlkopfverschluss' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Larynxobstruktion')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[702].designation[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Larynxhindernis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Larynxschleimhautentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[703].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kehlkopfschleimhautentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Larynxschleimhautentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[703].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'laryngeale Mukositis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Larynxschleimhautentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[703].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Larynxmukositis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Larynxschleimhautentzündung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[703].designation[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kehlkopfverenugung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Larynxstenose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[704].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Larynxverenungung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Larynxstenose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[704].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Pulmonalfibrose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Lungenfibrose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[705].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'interstitielle Lungenerkrankung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Lungenfibrose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[705].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Pulmonalfistel' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Lungenfistel')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[706].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Pulmonales Ödem' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Lungenödem')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[707].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Wasserlunge' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Lungenödem')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[707].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Mittelfellblutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Mediastinale Blutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[708].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'mediastinale Thoraxblutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Mediastinale Blutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[708].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Paranasale Sinuserkrankung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Nasennebenhöhlenerkrankung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[709].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Nasenkongestion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Nasenverstopfung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[710].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Niesen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[711].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Rachenschleimhautentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pharyngeale Mukositis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[712].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Pharynxschleimhautentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pharyngeale Mukositis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[712].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Pharynxmukositis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pharyngeale Mukositis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[712].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Rachenblutung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pharyngxblutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[713].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Rachenfistel' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pharynxfistel')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[714].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hypopharynsfistel' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pharynxfistel')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[714].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Rachen- Kehlkopf- Schmerzen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pharynx-Larynx-Schmerzen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[715].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Rachen- Hals- Schmerzen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pharynx-Larynx-Schmerzen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[715].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Rachennekrose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pharynxnekrose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[716].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Rachenverengung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pharynxstenose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[717].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Pharynxverengung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pharynxstenose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[717].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Pleurahämorrhagie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pleurablutung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[718].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Brustfellerguss' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pleuraerguss')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[719].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Pleuraeffusion' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pleuraerguss')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[719].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pleuraschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[720].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Pneu' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pneumothorax')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[721].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Husten mit Auswurf' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Produktiver Husten')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[722].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Husten mit Expektoration' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Produktiver Husten')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[722].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Lungenhochdruck' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pulmonale Hypertonie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[723].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Pulmonalhypertonie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pulmonale Hypertonie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[723].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hypertonie des kleinen Kreislaufs' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pulmonale Hypertonie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[723].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Lungenkreislaufhypertonus' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pulmonale Hypertonie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[723].designation[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Atemversagen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Respirationsversagen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[724].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Respiratorische Insuffizienz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Respirationsversagen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[724].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Respiratorisches Versagen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Respirationsversagen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[724].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'ATRA'-Syndrom' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Retinsäure Syndrom')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[725].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Retinolsäuresyndrom' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Retinsäure Syndrom')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[725].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Schlaf-Apnoe Syndrom (SAS)')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[726].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hicksen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Schluckauf')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[727].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Airway Cough Syndrome' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Sinubronchiales Syndrom')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[728].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'UACS' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Sinubronchiales Syndrom')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[728].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Postnasal'-Drip'-Syndrom' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Sinubronchiales Syndrom')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[728].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'PNDS' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Sinubronchiales Syndrom')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[728].designation[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Stimmänderung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[729].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Atemgeräusch' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Stridor')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[730].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Luftröhrenfistel' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Trachealfistel')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[731].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Luftröhrenstenose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Trachealstenose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[732].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Luftföhrenversagung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Trachealstenose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[732].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Luftröhrenschleimhautentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Tracheitis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[733].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Tracheale Mukositis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Tracheitis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[733].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Störungen der Atmungsorgane, des Thorax und Mediastinums - Sonstige,  zu spezifizieren')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[734].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Akneähnlicher Ausschlag' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Akneiformes Exanthem')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[735].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Blasige Hautentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Bullöse Dermatitis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[736].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Dermatitis mit Blausenbildung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Bullöse Dermatitis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[736].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Erythema multiforme' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Erythema exsudativum multiforme')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[737].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hautrötung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Erythrodemie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[738].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Fettschwund' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Fettatrophie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[739].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Alopezie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Haarausfall')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[740].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Alopecia' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Haarausfall')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[740].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Palmarplantare' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hand-Fuß-Syndrom')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[741].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Erythrodyästhesie PPE' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hand-Fuß-Syndrom')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[741].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hautschwund' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hautatropie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[742].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Chloasma' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hauthyperpigmentierung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[743].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Melasma' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hauthyperpigmentierung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[743].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Depigemtierung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hauthypopigmentierung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[744].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hautschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[745].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hautinduration' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hautverhärtung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[746].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'kutane Induration' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hautverhärtung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[746].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Vermehrte Behaarung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hirsutismus')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[747].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Vermehrte Schweißbildung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hyperhidrose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[748].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Verstärkte Behaarung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypertrichosis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[749].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'starke Behaarung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypertrichosis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[749].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Verminderte Schweißbildung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypohidrose')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[750].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Schweißgeruch Ketose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Körpergeruch')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[751].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Kopfhautschmerz')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[752].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Photosensibilität' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Lichtempfindlichkeit')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[753].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Photohypersensibilität' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Lichtempfindlichkeit')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[753].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Lichtüberempfindlichkeit' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Lichtempfindlichkeit')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[753].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Vermehrung von Fettgewebe' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Lipohypertrophy')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[754].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Medikamentöse bedingte toxische Nekrolyse der Epidermis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Lyell-Syndrom medikamentöses')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[755].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'toxic epidermal necrolysis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Lyell-Syndrom medikamentöses')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[755].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'TEN' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Lyell-Syndrom medikamentöses')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[755].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Knotigfleckiger Hautausschlag' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Makulopapulöses Hautexanthem')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[756].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'makulopapulöses Exanthem' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Makulopapulöses Hautexanthem')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[756].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Nageldiskoloration' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Nagelverfärbungen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[757].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Nagelausfall' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Nagelverlust')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[758].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Nagelfurchen' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Nagelrinnen')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[759].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Periorbitale Schwelllung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Periorbitales Ödem')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[760].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Augenhöhlenschwellung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Periorbitales Ödem')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[760].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Augenödem' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Periorbitales Ödem')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[760].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Juckreiz' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Pruritus')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[761].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Kapilarbutungen der Haut, Unterhaut oder Schleimhäuten' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Purpura')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[762].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Petichien' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Purpura')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[762].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Rötung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Purpura')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[762].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Dermatostomatitis Baader' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Stevens-Johnson-Syndrom, SJS')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[763].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Fiessinger'-Rendu'-Syndrom' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Stevens-Johnson-Syndrom, SJS')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[763].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'bullöses Erythema exsudativum multiforme' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Stevens-Johnson-Syndrom, SJS')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[763].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'kutane Arzneimittelhautallergie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Stevens-Johnson-Syndrom, SJS')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[763].designation[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'infektallergische Hautallergie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Stevens-Johnson-Syndrom, SJS')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[763].designation[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Erweiterung der (kapillären) Haut'-Blutgefäße' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Teleangiektasie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[764].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Trockene Haut')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[765].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hautulzeration' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ulzeration der Haut')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[766].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hautulceration' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ulzeration der Haut')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[766].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hautgeschwürbildung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ulzeration der Haut')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[766].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hautulkus' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ulzeration der Haut')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[766].designation[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hautulcus' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ulzeration der Haut')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[766].designation[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Druck'- und Lagerungsschäden, z.B. Dekubitalulzera' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Ulzeration der Haut')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[766].designation[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Nesselfiber' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Urtikaria')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[767].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Nesselsucht' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Urtikaria')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[767].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Störungen der Haut und Unterhautgewebe - Sonstige, zu spezifizieren')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[768].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Klimakterium' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Menopause')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[769].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Wechseljahre' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Menopause')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[769].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Störungen der sozialen Umstände - Sonstige, zu spezifizieren')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[770].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Chirurgische und medizinische Prozeduren - Sonstige,  zu spezifizieren')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[771].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Flush' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hautrötung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[772].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Errötung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hautrötung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[772].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Wundhämatom (konservativ therapiert)' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hämatom')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[773].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hitzewallung')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[774].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Bluthochdruck' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypertonie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[775].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hypertonus' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypertonie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[775].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hochdruck' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypertonie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[775].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Blutdruckerniedrigung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypotonie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[776].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Hypotonus' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypotonie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[776].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Blultdruckabfall' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypotonie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[776].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'niedriger Blutdruck' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Hypotonie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[776].designation[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Clarkson'-Syndrom' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Kapillarlecksyndrom')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[777].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'capillary leakage syndrome, CLS' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Kapillarlecksyndrom')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[777].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'systemic capillary leak syndrome, SCLS' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Kapillarlecksyndrom')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[777].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Lymphleck' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Lymphaustritt')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[778].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Lymphleckage' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Lymphaustritt')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[778].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Lymphschwellung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Lymphödem')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[779].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Lymphansammlung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Lymphozele')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[780].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Periphere Durchblutungsstörung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Periphere Ischämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[781].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'peripherer arterieller Verschluß' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Periphere Ischämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[781].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'arterielle Embolie/Thrombose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Periphere Ischämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[781].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Venenentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Phlebitis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[782].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Thromboembolie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Thromboembolisches Ereignis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[783].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Ileofemorale Venenthrombose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Thromboembolisches Ereignis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[783].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Pulmonalarterienembolie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Thromboembolisches Ereignis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[783].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Embolie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Thromboembolisches Ereignis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[783].designation[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'thrombotischer Gefäßverschluss' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Thromboembolisches Ereignis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[783].designation[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Oberflächen'-Thrombophlebitis' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Thrombophlebitis, oberflächliche')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[784].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Gefäßwandentzündung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vaskulitis')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[785].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Syndrom der oberen Einflussstauung' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vena-cava-superior-(VCS) Syndrom')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[786].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Vena Cava Syndrom' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vena-cava-superior-(VCS) Syndrom')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[786].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Viszerale Ischämie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Viszerale arterielle Ischämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[787].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Leriche- Syndrom' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Viszerale arterielle Ischämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[787].designation[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Bauchschlagaderischämie' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Viszerale arterielle Ischämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[787].designation[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation 'Mesesenterialarterien- oder venenthrombose' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Viszerale arterielle Ischämie')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[787].designation[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 1233476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CODESYSTEM_DESIGNATION_DISP_CLASH_LANG"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The designation '-' has no use and is in the same language ('de-DE'), so is not differentiated from the base display ('Vaskuläre Störung  - Sonstige,  zu spezifizieren')"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem.concept[788].designation[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 795962
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Language_XHTML_Lang_Different1"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-publishablecodesystem|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "Resource has a language (de-DE), and the XHTML has a lang (en), but they differ"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-nebenwirkung-meddra-de: CodeSystem"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/CodeSystem-mii-cs-onko-operation-komplikation",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-mii-cs-onko-operation-komplikation",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 430
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-operation-komplikation: CodeSystem.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28858
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-operation-komplikation: CodeSystem.jurisdiction[0].coding[0].system"
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          }
        ]
      }
    },
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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              {
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            ],
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            },
            "expression": [
              "CodeSystem/mii-cs-onko-operation-urgency: CodeSystem.meta.extension[1].extension[2].value.ofType(uri)"
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          {
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    },
    {
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            "expression": [
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          {
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              {
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            "expression": [
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        ]
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    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/CodeSystem-mii-cs-onko-prostata-postsurgical-complications",
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            "expression": [
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          {
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            ],
            "severity": "warning",
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    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/CodeSystem-mii-cs-onko-residualstatus",
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    },
    {
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        "resourceType": "OperationOutcome",
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              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-strahlentherapie-zielgebiet-2014'"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-strahlentherapie-zielgebiet-2014: CodeSystem.valueSet"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/CodeSystem-mii-cs-onko-strahlentherapie-zielgebiet",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-mii-cs-onko-strahlentherapie-zielgebiet",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 435
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-strahlentherapie-zielgebiet: CodeSystem.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 34417
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-strahlentherapie-zielgebiet: CodeSystem.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CodeSystem_CS_VS_Invalid"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "CodeSystem https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-strahlentherapie-zielgebiet has an 'all system' value set of https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-strahlentherapie-zielgebiet, but the value set doesn't have a single include"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-strahlentherapie-zielgebiet: CodeSystem"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/CodeSystem-mii-cs-onko-studienteilnahme",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-mii-cs-onko-studienteilnahme",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 424
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-studienteilnahme: CodeSystem.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6775
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-studienteilnahme: CodeSystem.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/CodeSystem-mii-cs-onko-systemische-therapie-protokolle",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-mii-cs-onko-systemische-therapie-protokolle",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 439
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-systemische-therapie-protokolle: CodeSystem.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68378
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-systemische-therapie-protokolle: CodeSystem.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/CodeSystem-mii-cs-onko-therapie-ende-grund",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-mii-cs-onko-therapie-ende-grund",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 427
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-therapie-ende-grund: CodeSystem.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8974
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-therapie-ende-grund: CodeSystem.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/CodeSystem-mii-cs-onko-therapie-stellungzurop",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-mii-cs-onko-therapie-stellungzurop",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 430
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-therapie-stellungzurop: CodeSystem.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7706
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-therapie-stellungzurop: CodeSystem.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/CodeSystem-mii-cs-onko-therapie-typ",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-mii-cs-onko-therapie-typ",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 420
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-therapie-typ: CodeSystem.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10289
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-therapie-typ: CodeSystem.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/CodeSystem-mii-cs-onko-therapieabweichung",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-mii-cs-onko-therapieabweichung",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 426
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-therapieabweichung: CodeSystem.meta.extension[1].extension[2].value.ofType(uri)"
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          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6843
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-therapieabweichung: CodeSystem.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/CodeSystem-mii-cs-onko-therapieplanung-typ",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-mii-cs-onko-therapieplanung-typ",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 427
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-therapieplanung-typ: CodeSystem.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7648
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-therapieplanung-typ: CodeSystem.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/CodeSystem-mii-cs-onko-tnm-formel",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-mii-cs-onko-tnm-formel",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 418
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
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            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-tnm-formel: CodeSystem.meta.extension[1].extension[2].value.ofType(uri)"
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          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6715
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-tnm-formel: CodeSystem.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/CodeSystem-mii-cs-onko-tnm-uicc",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-mii-cs-onko-tnm-uicc",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38860
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-tnm-uicc: CodeSystem.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/CodeSystem-mii-cs-onko-tnm-version",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-mii-cs-onko-tnm-version",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 419
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-tnm-version: CodeSystem.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8083
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-tnm-version: CodeSystem.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/CodeSystem-mii-cs-onko-tod",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-mii-cs-onko-tod",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 411
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-tod: CodeSystem.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7060
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-tod: CodeSystem.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/CodeSystem-mii-cs-onko-verlauf-fernmetastasen",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-mii-cs-onko-verlauf-fernmetastasen",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 430
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-verlauf-fernmetastasen: CodeSystem.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8418
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-verlauf-fernmetastasen: CodeSystem.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/CodeSystem-mii-cs-onko-verlauf-gesamtbeurteilung",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-mii-cs-onko-verlauf-gesamtbeurteilung",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 433
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-verlauf-gesamtbeurteilung: CodeSystem.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9249
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-verlauf-gesamtbeurteilung: CodeSystem.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/CodeSystem-mii-cs-onko-verlauf-lymphknoten",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-mii-cs-onko-verlauf-lymphknoten",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 427
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-verlauf-lymphknoten: CodeSystem.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8373
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-verlauf-lymphknoten: CodeSystem.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/CodeSystem-mii-cs-onko-verlauf-primaertumor",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-mii-cs-onko-verlauf-primaertumor",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 428
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-verlauf-primaertumor: CodeSystem.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8305
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablecodesystem|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-verlauf-primaertumor: CodeSystem.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/CodeSystem-mii-cs-onko-weitere-klassifikationen-obds",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-mii-cs-onko-weitere-klassifikationen-obds",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 437
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecodesystem|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-weitere-klassifikationen-obds: CodeSystem.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 113946
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecodesystem|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-weitere-klassifikationen-obds: CodeSystem.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 142213
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecodesystem#scs-1"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablecodesystem|2.0.0"
              }
            ],
            "severity": "error",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: scs-1: 'If a codesystem contains nested concepts, it must specify hierarchyMeaning (concept.concept.exists() implies hierarchyMeaning.exists())'"
            },
            "expression": [
              "CodeSystem/mii-cs-onko-weitere-klassifikationen-obds: CodeSystem"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/CodeSystem-radelement",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "CodeSystem-radelement",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2293
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/CodeSystem|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "CodeSystem/radelement: CodeSystem.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-mii-to-mvgenomseq-condition-diagnose-primaertumor",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-mii-to-mvgenomseq-condition-diagnose-primaertumor",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6078
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Validation_VAL_Profile_Minimum"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "ConceptMap.title: minimum required = 1, but only found 0 (from http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0)"
            },
            "expression": [
              "ConceptMap/mii-cm-mii-to-mvgenomseq-condition-diagnose-primaertumor: ConceptMap"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6078
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Validation_VAL_Profile_Minimum"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "ConceptMap.description: minimum required = 1, but only found 0 (from http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0)"
            },
            "expression": [
              "ConceptMap/mii-cm-mii-to-mvgenomseq-condition-diagnose-primaertumor: ConceptMap"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 452
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-mii-to-mvgenomseq-condition-diagnose-primaertumor: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 5811
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-mii-to-mvgenomseq-condition-diagnose-primaertumor: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 5955
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_RESOLVE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "A definition could not be found for Canonical URL 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onkologie/StructureDefinition/mii-pr-onko-diagnose-primaertumor'"
            },
            "expression": [
              "ConceptMap/mii-cm-mii-to-mvgenomseq-condition-diagnose-primaertumor: ConceptMap.source.ofType(canonical)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6077
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onkologie/ConceptMap/mii-lm-mvgenomseq-onkologie'"
            },
            "expression": [
              "ConceptMap/mii-cm-mii-to-mvgenomseq-condition-diagnose-primaertumor: ConceptMap.target.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6078
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_SHAREABLE_MISSING"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Published concept maps SHOULD conform to the ShareableConceptMap profile, which says that the element ConceptMap.title is mandatory, but it is not present"
            },
            "expression": [
              "ConceptMap/mii-cm-mii-to-mvgenomseq-condition-diagnose-primaertumor: ConceptMap"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6078
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_SHAREABLE_EXTRA_MISSING"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Published concept maps SHOULD conform to the ShareableConceptMap profile, which says that the element ConceptMap.name should be present, but it is not"
            },
            "expression": [
              "ConceptMap/mii-cm-mii-to-mvgenomseq-condition-diagnose-primaertumor: ConceptMap"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6078
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_SHAREABLE_MISSING"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Published concept maps SHOULD conform to the ShareableConceptMap profile, which says that the element ConceptMap.description is mandatory, but it is not present"
            },
            "expression": [
              "ConceptMap/mii-cm-mii-to-mvgenomseq-condition-diagnose-primaertumor: ConceptMap"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-allgemeiner-leistungszustand-ecog-loinc",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-allgemeiner-leistungszustand-ecog-loinc",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 447
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-allgemeiner-leistungszustand-ecog-loinc: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11652
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-allgemeiner-leistungszustand-ecog-loinc: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 13919
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_SHAREABLE_EXTRA_MISSING"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Published concept maps SHOULD conform to the ShareableConceptMap profile, which says that the element ConceptMap.name should be present, but it is not"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-allgemeiner-leistungszustand-ecog-loinc: ConceptMap"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12258
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA9622-7' in the system http://loinc.org is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-allgemeiner-leistungszustand-ecog-loinc: ConceptMap.group[0].element[0].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12618
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA9623-5' in the system http://loinc.org is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-allgemeiner-leistungszustand-ecog-loinc: ConceptMap.group[0].element[1].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12997
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA9624-3' in the system http://loinc.org is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-allgemeiner-leistungszustand-ecog-loinc: ConceptMap.group[0].element[2].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 13345
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA9625-0' in the system http://loinc.org is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-allgemeiner-leistungszustand-ecog-loinc: ConceptMap.group[0].element[3].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 13651
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA9626-8' in the system http://loinc.org is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-allgemeiner-leistungszustand-ecog-loinc: ConceptMap.group[0].element[4].target[0].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-allgemeiner-leistungszustand-karnofsky-loinc",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-allgemeiner-leistungszustand-karnofsky-loinc",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 452
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-allgemeiner-leistungszustand-karnofsky-loinc: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12569
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-allgemeiner-leistungszustand-karnofsky-loinc: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14798
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_SHAREABLE_EXTRA_MISSING"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Published concept maps SHOULD conform to the ShareableConceptMap profile, which says that the element ConceptMap.name should be present, but it is not"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-allgemeiner-leistungszustand-karnofsky-loinc: ConceptMap"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 13112
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA29175-9' in the system http://loinc.org is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-allgemeiner-leistungszustand-karnofsky-loinc: ConceptMap.group[0].element[0].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 13260
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA29176-7' in the system http://loinc.org is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-allgemeiner-leistungszustand-karnofsky-loinc: ConceptMap.group[0].element[1].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 13431
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA29177-5' in the system http://loinc.org is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-allgemeiner-leistungszustand-karnofsky-loinc: ConceptMap.group[0].element[2].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 13596
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA29178-3' in the system http://loinc.org is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-allgemeiner-leistungszustand-karnofsky-loinc: ConceptMap.group[0].element[3].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 13767
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA29179-1' in the system http://loinc.org is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-allgemeiner-leistungszustand-karnofsky-loinc: ConceptMap.group[0].element[4].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 13935
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA29180-9' in the system http://loinc.org is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-allgemeiner-leistungszustand-karnofsky-loinc: ConceptMap.group[0].element[5].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14096
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA29181-7' in the system http://loinc.org is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-allgemeiner-leistungszustand-karnofsky-loinc: ConceptMap.group[0].element[6].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14245
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA29182-5' in the system http://loinc.org is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-allgemeiner-leistungszustand-karnofsky-loinc: ConceptMap.group[0].element[7].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14424
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA29183-3' in the system http://loinc.org is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-allgemeiner-leistungszustand-karnofsky-loinc: ConceptMap.group[0].element[8].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14602
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA29184-1' in the system http://loinc.org is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-allgemeiner-leistungszustand-karnofsky-loinc: ConceptMap.group[0].element[9].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14747
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA9627-6' in the system http://loinc.org is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-allgemeiner-leistungszustand-karnofsky-loinc: ConceptMap.group[0].element[10].target[0].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-allgemeiner-leistungszustand-sct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-allgemeiner-leistungszustand-sct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 440
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-allgemeiner-leistungszustand-sct: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11400
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-allgemeiner-leistungszustand-sct: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11927
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-allgemeiner-leistungszustand-sct: ConceptMap.source.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12000
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-allgemeiner-leistungszustand-sct: ConceptMap.target.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12212
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-allgemeiner-leistungszustand-sct: ConceptMap.group[0].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 13860
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ConceptMap#cmd-0"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: cmd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))' (defined in http://hl7.org/fhir/StructureDefinition/ConceptMap)"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-allgemeiner-leistungszustand-sct: ConceptMap"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-asa-obds-loinc",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-asa-obds-loinc",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 422
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-asa-obds-loinc: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9479
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-asa-obds-loinc: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9925
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA28813-6' in the system http://loinc.org is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-asa-obds-loinc: ConceptMap.group[0].element[0].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10034
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA28814-4' in the system http://loinc.org is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-asa-obds-loinc: ConceptMap.group[0].element[1].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10145
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA28815-1' in the system http://loinc.org is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-asa-obds-loinc: ConceptMap.group[0].element[2].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10256
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA28816-9' in the system http://loinc.org is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-asa-obds-loinc: ConceptMap.group[0].element[3].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10365
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA28817-7' in the system http://loinc.org is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-asa-obds-loinc: ConceptMap.group[0].element[4].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10474
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA28818-5' in the system http://loinc.org is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-asa-obds-loinc: ConceptMap.group[0].element[5].target[0].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-atc-transitions-2021",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-atc-transitions-2021",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 428
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37078
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37645
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37694
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[0].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37830
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE06' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37880
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA02' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[1].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37950
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE08' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[2].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38000
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA03' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[2].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38070
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE14' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[3].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38120
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA04' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[3].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38190
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE24' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[4].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38240
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA05' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[4].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38310
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE02' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[5].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38360
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[5].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38494
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE03' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[6].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38544
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB02' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[6].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38614
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE13' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[7].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38663
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB03' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[7].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38732
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE35' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[8].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38784
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB04' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[8].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38856
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE15' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[9].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38908
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EC01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[9].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39030
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE23' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[10].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39081
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EC02' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[10].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39152
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE46' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[11].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39204
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EC03' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[11].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39276
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE16' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[12].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39327
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[12].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39447
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE28' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[13].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39497
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED02' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[13].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39567
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE36' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[14].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39617
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED03' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[14].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39687
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE43' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[15].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39738
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED04' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[15].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39809
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE44' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[16].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39860
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED05' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[16].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39931
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE25' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[17].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39982
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[17].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40102
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE38' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[18].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40154
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE02' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[18].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40226
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE41' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[19].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40278
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE03' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[19].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40350
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE33' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[20].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40402
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EF01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[20].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40526
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE42' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[21].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40577
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EF02' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[21].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40648
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE50' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[22].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40700
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EF03' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[22].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40772
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE09' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[23].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40825
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EG01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[23].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40948
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE10' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[24].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40999
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EG02' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[24].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41070
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE07' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[25].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41120
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EH01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[25].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41240
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE45' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[26].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41290
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EH02' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[26].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41360
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE18' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[27].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41412
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EJ01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[27].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41533
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE17' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[28].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41582
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EK01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[28].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41702
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE34' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[29].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41752
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EK03' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[29].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41822
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE27' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[30].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41872
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EL01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[30].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41991
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE51' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[31].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42045
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EL02' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[31].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42119
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX47' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[32].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42170
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EM01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[32].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42291
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX61' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[33].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42342
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EM02' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[33].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42413
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE04' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[34].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42463
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[34].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42599
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE05' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[35].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42649
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX02' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[35].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42719
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE12' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[36].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42770
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX04' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[36].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42841
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE21' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[37].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42893
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX05' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[37].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42965
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE26' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[38].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43018
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX07' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[38].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43091
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE29' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[39].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43142
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX08' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[39].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43213
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE31' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[40].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43264
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX09' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[40].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43335
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE39' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[41].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43387
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX10' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[41].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43459
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE52' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[42].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43511
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX11' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[42].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43583
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE53' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[43].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43637
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX12' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[43].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43711
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE54' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[44].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43764
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX13' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[44].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43837
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX14' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[45].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43887
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XF01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[45].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44000
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX22' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[46].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44053
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XF02' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[46].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44126
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX25' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[47].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44176
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XF03' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[47].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44246
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX32' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[48].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44297
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XG01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[48].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44423
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX45' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[49].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44475
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XG02' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[49].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44547
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX50' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[50].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44596
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XG03' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[50].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44665
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX38' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[51].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44716
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XH01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[51].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44851
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX39' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[52].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44902
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XH02' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[52].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44973
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX42' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[53].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45026
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XH03' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[53].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45099
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX49' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[54].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45150
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XH04' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[54].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45221
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX43' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[55].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45272
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XJ01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[55].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45407
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX63' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[56].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45457
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XJ03' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[56].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45527
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX46' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[57].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45576
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[57].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45695
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX54' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[58].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45745
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK02' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[58].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45815
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX60' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[59].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45867
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK04' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[59].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45939
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX17' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[60].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45989
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CE01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[60].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46120
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX19' in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[61].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46171
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CE02' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2021: ConceptMap.group[0].element[61].target[0].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-atc-transitions-2022",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-atc-transitions-2022",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 428
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17918
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18447
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC02' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18497
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FA01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[0].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18617
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC15' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18670
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FA03' in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[1].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18793
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC26' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[2].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18855
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FB01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[2].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18987
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC24' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[3].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19039
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FC01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[3].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19161
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC03' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[4].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19213
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[4].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19335
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC13' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[5].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19386
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD02' in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[5].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19507
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC14' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[6].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19568
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD03' in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[6].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19699
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC06' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[7].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19749
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FE01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[7].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19869
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC08' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[8].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19921
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FE02' in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[8].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20043
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC17' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[9].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20093
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[9].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20220
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC18' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[10].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20274
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF02' in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[10].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20405
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC28' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[11].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20456
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF03' in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[11].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20584
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC31' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[12].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20633
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF04' in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[12].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20759
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC32' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[13].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20812
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF05' in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[13].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20942
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC07' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[14].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20994
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FG01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[14].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21123
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC21' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[15].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21175
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FG02' in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[15].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21304
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC11' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[16].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21355
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX04' in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[16].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21489
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC12' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[17].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21549
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX05' in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[17].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21692
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC19' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[18].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21745
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX07' in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[18].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21881
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC27' in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[19].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21932
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX10' in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2022: ConceptMap.group[0].element[19].target[0].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-atc-transitions-2023",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-atc-transitions-2023",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 428
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2023: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8321
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2023: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8850
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX70' in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2023: ConceptMap.group[0].element[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8913
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL03' in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2023: ConceptMap.group[0].element[0].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9049
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX51' in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2023: ConceptMap.group[0].element[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9113
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL02' in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2023: ConceptMap.group[0].element[1].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9249
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX71' in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2023: ConceptMap.group[0].element[2].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9306
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL04' in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2023: ConceptMap.group[0].element[2].target[0].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-atc-transitions-2024",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-atc-transitions-2024",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 428
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2024: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14312
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2024: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14855
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA34' in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2024: ConceptMap.group[0].element[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14907
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AG06' in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2024: ConceptMap.group[0].element[0].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15040
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA26' in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2024: ConceptMap.group[0].element[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15090
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AG04' in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2024: ConceptMap.group[0].element[1].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15160
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA25' in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2024: ConceptMap.group[0].element[2].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15211
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AJ01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2024: ConceptMap.group[0].element[2].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15338
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA21' in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2024: ConceptMap.group[0].element[3].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15389
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AG02' in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2024: ConceptMap.group[0].element[3].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15460
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EG02' in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2024: ConceptMap.group[0].element[4].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15511
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AH02' in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2024: ConceptMap.group[0].element[4].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15666
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA27' in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2024: ConceptMap.group[0].element[5].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15717
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AE01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2024: ConceptMap.group[0].element[5].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15864
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA13' in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2024: ConceptMap.group[0].element[6].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15915
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AK01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2024: ConceptMap.group[0].element[6].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15986
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX24' in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2024: ConceptMap.group[0].element[7].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16040
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX25' in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2024: ConceptMap.group[0].element[7].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16181
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA02' in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2024: ConceptMap.group[0].element[8].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16235
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AG01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2024: ConceptMap.group[0].element[8].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16309
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA23' in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2024: ConceptMap.group[0].element[9].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16361
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AG03' in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2024: ConceptMap.group[0].element[9].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16433
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XY03' in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2024: ConceptMap.group[0].element[10].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16498
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FY02' in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2024: ConceptMap.group[0].element[10].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16654
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FA02' in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2024: ConceptMap.group[0].element[11].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16705
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AG12' in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2024: ConceptMap.group[0].element[11].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16860
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XY02' in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2024: ConceptMap.group[0].element[12].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16927
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FY01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2024: ConceptMap.group[0].element[12].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17085
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA10' in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2024: ConceptMap.group[0].element[13].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17135
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AH01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2024: ConceptMap.group[0].element[13].target[0].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-atc-transitions-2025",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-atc-transitions-2025",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 428
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2025: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7589
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2025: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8091
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX59' in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2025: ConceptMap.group[0].element[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8142
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XM01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2025: ConceptMap.group[0].element[0].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8262
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX62' in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2025: ConceptMap.group[0].element[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8313
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XM02' in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2025: ConceptMap.group[0].element[1].target[0].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-atc-transitions-2026",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-atc-transitions-2026",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 428
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2026: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7725
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2026: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8257
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX17' in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2026: ConceptMap.group[0].element[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8308
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EP01' in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2026: ConceptMap.group[0].element[0].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8462
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX21' in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2026: ConceptMap.group[0].element[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8512
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EP02' in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-atc-transitions-2026: ConceptMap.group[0].element[1].target[0].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-fernmetastasen-sct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-fernmetastasen-sct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 426
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-fernmetastasen-sct: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 13107
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-fernmetastasen-sct: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 13634
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-fernmetastasen-sct: ConceptMap.source.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 13707
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-fernmetastasen-sct: ConceptMap.target.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 13900
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-fernmetastasen-sct: ConceptMap.group[0].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15833
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ConceptMap#cmd-0"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: cmd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))' (defined in http://hl7.org/fhir/StructureDefinition/ConceptMap)"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-fernmetastasen-sct: ConceptMap"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-genetische-variante-auspraegung-sct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-genetische-variante-auspraegung-sct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 443
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-genetische-variante-auspraegung-sct: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9872
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-genetische-variante-auspraegung-sct: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10399
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-genetische-variante-auspraegung-sct: ConceptMap.source.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10472
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-genetische-variante-auspraegung-sct: ConceptMap.target.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10682
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-genetische-variante-auspraegung-sct: ConceptMap.group[0].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11557
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ConceptMap#cmd-0"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: cmd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))' (defined in http://hl7.org/fhir/StructureDefinition/ConceptMap)"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-genetische-variante-auspraegung-sct: ConceptMap"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-grading-sct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-grading-sct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 419
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-grading-sct: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 13879
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-grading-sct: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14406
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-grading-sct: ConceptMap.source.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14479
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-grading-sct: ConceptMap.target.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14665
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-grading-sct: ConceptMap.group[0].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16952
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ConceptMap#cmd-0"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: cmd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))' (defined in http://hl7.org/fhir/StructureDefinition/ConceptMap)"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-grading-sct: ConceptMap"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14688
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display 'primär erworbene Melanose ohne zelluläre Atypien (nur beim malignen Melanom der Konjunktiva)' for the code 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-grading|2027.0.0-ballot.1#0' is not valid. Possible displays: 'primär erworbene Melanose ohne zelluläre Atypien'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-grading-sct: ConceptMap.group[0].element[0].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-icdo3-transitions-2019",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-icdo3-transitions-2019",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 430
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62354
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62920
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8151/0' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62976
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8151/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[0].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63119
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8152/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63176
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8152/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[1].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63313
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8153/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[2].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63369
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8153/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[2].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63861
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8156/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[3].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63922
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8156/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[3].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64072
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8240/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[4].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64146
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8240/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[4].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64301
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8242/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[5].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64384
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8242/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[5].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64552
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8336/0' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[6].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64626
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8336/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[6].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64788
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8444/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[7].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64883
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8313/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[7].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65039
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8581/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[8].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65102
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8581/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[8].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65245
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8582/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[9].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65309
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8582/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[9].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65453
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8583/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[10].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65517
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8583/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[10].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65661
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8584/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[11].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65725
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8584/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[11].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65869
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8585/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[12].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65933
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8585/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[12].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66077
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8680/0' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[13].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66138
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8680/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[13].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66284
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8680/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[14].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66343
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8680/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[14].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66489
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8681/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[15].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66555
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8681/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[15].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66708
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8682/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[16].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66778
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8682/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[16].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66935
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8690/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[17].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67003
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8690/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[17].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67157
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8691/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[18].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67218
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8691/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[18].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67366
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8692/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[19].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67428
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8692/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[19].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67588
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8693/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[20].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67662
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8693/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[20].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67823
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8700/0' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[21].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67885
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8700/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[21].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68034
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8833/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[22].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68119
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8833/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[22].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68291
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8841/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[23].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68341
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8841/0' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[23].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68485
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8936/0' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[24].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68564
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8936/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[24].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68721
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8936/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[25].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68798
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8936/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[25].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68955
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '9055/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[26].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69023
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '9055/0' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[26].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69178
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '9133/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[27].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69256
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '9133/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[27].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69422
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '9150/0' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[28].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69488
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8815/0' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[28].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69665
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '9150/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[29].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69729
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8815/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[29].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69887
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '9150/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[30].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69953
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8815/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[30].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70113
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '9230/0' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[31].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70174
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '9230/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[31].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70322
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '9260/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[32].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70374
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '9364/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[32].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70513
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '9341/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[33].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70578
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '9341/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[33].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70738
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '9670/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[34].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70838
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '9823/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[34].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71042
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '9725/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[35].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71116
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '9725/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[35].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71292
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '9728/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[36].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71390
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '9811/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[36].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71561
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '9729/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[37].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71659
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '9837/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[37].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71823
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '9826/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[38].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71893
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '9687/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[38].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72082
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '9836/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[39].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72168
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '9811/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[39].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72339
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '9971/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[40].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72440
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '9971/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[40].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72633
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8460/0' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[41].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72702
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8441/0' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[41].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72852
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8462/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[42].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72951
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8442/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[42].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 73107
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8463/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[43].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 73206
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8442/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[43].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 73362
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8471/0' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[44].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 73440
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8470/0' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[44].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 73592
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8471/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[45].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 73670
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8470/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[45].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 73829
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8473/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[46].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 73926
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8472/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[46].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 74103
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '9991/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[47].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 74165
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '9980/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[47].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 74346
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '9992/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[48].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 74413
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '9980/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[48].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 74594
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8120/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[49].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 74656
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8120/0' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[49].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 74807
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8120/2' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[49].target[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 74961
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8120/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[49].target[2].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75120
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8150/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[50].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75191
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8150/0' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[50].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75356
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8150/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[50].target[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75531
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8158/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[51].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75608
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8158/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[51].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75764
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8408/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[52].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75843
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8408/0' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[52].target[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75998
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8408/3' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2019 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[52].target[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 76163
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8965/0' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[53].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 76371
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '9530/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[54].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 76609
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_VS_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '9540/1' in the system http://terminology.hl7.org/CodeSystem/icd-o-3 version 2014 is not valid in the value set 'null'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-icdo3-transitions-2019: ConceptMap.group[0].element[55].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-intention-sct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-intention-sct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 421
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-intention-sct: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10472
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-intention-sct: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10999
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-intention-sct: ConceptMap.source.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11072
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-intention-sct: ConceptMap.target.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11260
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-intention-sct: ConceptMap.group[0].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12437
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ConceptMap#cmd-0"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: cmd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))' (defined in http://hl7.org/fhir/StructureDefinition/ConceptMap)"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-intention-sct: ConceptMap"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-krk-stoma-obds-sct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-krk-stoma-obds-sct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 426
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-krk-stoma-obds-sct: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8223
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-krk-stoma-obds-sct: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9575
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_TARGET_UNKNOWN"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "The Target Code System http://snomed.info/sct is not fully defined and populated, and no targetScope is specified, so the target code checking will not be performed"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-krk-stoma-obds-sct: ConceptMap.group[0].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9577
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_SHAREABLE_EXTRA_MISSING"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "Published concept maps SHOULD conform to the ShareableConceptMap profile, which says that the element ConceptMap.name should be present, but it is not"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-krk-stoma-obds-sct: ConceptMap"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-nebenwirkung-meddra-sct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-nebenwirkung-meddra-sct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 431
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-nebenwirkung-meddra-sct: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 441851
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-nebenwirkung-meddra-sct: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 442206
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20260501?fhir_vs'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-nebenwirkung-meddra-sct: ConceptMap.target.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 579070
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_INCOMPLETE"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "Source Code System https://www.meddra.org doesn't have all content (content = fragment), so the source codes cannot be checked"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-nebenwirkung-meddra-sct: ConceptMap.group[0].source"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-nebenwirkung-sct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-nebenwirkung-sct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 424
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-nebenwirkung-sct: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10046
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-nebenwirkung-sct: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10573
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-nebenwirkung-sct: ConceptMap.source.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10646
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-nebenwirkung-sct: ConceptMap.target.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10848
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-nebenwirkung-sct: ConceptMap.group[0].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11815
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ConceptMap#cmd-0"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: cmd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))' (defined in http://hl7.org/fhir/StructureDefinition/ConceptMap)"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-nebenwirkung-sct: ConceptMap"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-operation-komplikation-sct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-operation-komplikation-sct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 434
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-operation-komplikation-sct: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52522
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-operation-komplikation-sct: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53049
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-operation-komplikation-sct: ConceptMap.source.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53122
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-operation-komplikation-sct: ConceptMap.target.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53323
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-operation-komplikation-sct: ConceptMap.group[0].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56574
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_String_WS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "value should not start or finish with whitespace 'Cholangitis (disorder) '"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-operation-komplikation-sct: ConceptMap.group[0].element[17].target[0].display"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67490
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ConceptMap#cmd-0"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: cmd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))' (defined in http://hl7.org/fhir/StructureDefinition/ConceptMap)"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-operation-komplikation-sct: ConceptMap"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-primaertumor-diagnosesicherung-sct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-primaertumor-diagnosesicherung-sct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 442
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-primaertumor-diagnosesicherung-sct: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16253
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-primaertumor-diagnosesicherung-sct: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16780
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-primaertumor-diagnosesicherung-sct: ConceptMap.source.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16853
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-primaertumor-diagnosesicherung-sct: ConceptMap.target.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17062
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-primaertumor-diagnosesicherung-sct: ConceptMap.group[0].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20068
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ConceptMap#cmd-0"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: cmd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))' (defined in http://hl7.org/fhir/StructureDefinition/ConceptMap)"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-primaertumor-diagnosesicherung-sct: ConceptMap"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19534
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display 'histologische Untersuchung des Gewebes bei Autopsie' for the code 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-primaertumor-diagnosesicherung|2027.0.0-ballot.1#7.3' is not valid. Possible displays: 'Histologie der Autopsie'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-primaertumor-diagnosesicherung-sct: ConceptMap.group[0].element[13].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-residualstatus-uicc-sct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-residualstatus-uicc-sct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 431
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-residualstatus-uicc-sct: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9599
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-residualstatus-uicc-sct: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10051
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.uicc.org/resources/r-classification'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-residualstatus-uicc-sct: ConceptMap.group[0].source"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10121
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-residualstatus-uicc-sct: ConceptMap.group[0].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11191
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ConceptMap#cmd-0"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: cmd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))' (defined in http://hl7.org/fhir/StructureDefinition/ConceptMap)"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-residualstatus-uicc-sct: ConceptMap"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11189
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_UNKNOWN"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "The Source Code System https://www.uicc.org/resources/r-classification is not fully defined and populated, and no sourceScope is specified, so the source code checking will not be performed"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-residualstatus-uicc-sct: ConceptMap.group[0].source"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11189
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_TARGET_UNKNOWN"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "The Target Code System http://snomed.info/sct/900000000000207008/version/20240401 is not fully defined and populated, and no targetScope is specified, so the target code checking will not be performed"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-residualstatus-uicc-sct: ConceptMap.group[0].target"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-seitenlokalisation-sct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-seitenlokalisation-sct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 430
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-seitenlokalisation-sct: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9611
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-seitenlokalisation-sct: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10138
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-seitenlokalisation-sct: ConceptMap.source.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10211
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-seitenlokalisation-sct: ConceptMap.target.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10408
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-seitenlokalisation-sct: ConceptMap.group[0].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10639
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_String_WS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "value should not start or finish with whitespace 'Right (qualifier value) '"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-seitenlokalisation-sct: ConceptMap.group[0].element[1].target[0].display"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11229
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ConceptMap#cmd-0"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: cmd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))' (defined in http://hl7.org/fhir/StructureDefinition/ConceptMap)"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-seitenlokalisation-sct: ConceptMap"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-strahlentherapie-applikationsart-sct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-strahlentherapie-applikationsart-sct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 444
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-strahlentherapie-applikationsart-sct: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18150
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-strahlentherapie-applikationsart-sct: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18677
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-strahlentherapie-applikationsart-sct: ConceptMap.source.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18750
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-strahlentherapie-applikationsart-sct: ConceptMap.target.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18961
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-strahlentherapie-applikationsart-sct: ConceptMap.group[0].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 22633
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ConceptMap#cmd-0"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: cmd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))' (defined in http://hl7.org/fhir/StructureDefinition/ConceptMap)"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-strahlentherapie-applikationsart-sct: ConceptMap"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-strahlentherapie-boost-sct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-strahlentherapie-boost-sct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 434
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-strahlentherapie-boost-sct: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9310
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-strahlentherapie-boost-sct: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9837
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-strahlentherapie-boost-sct: ConceptMap.source.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9910
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-strahlentherapie-boost-sct: ConceptMap.target.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10111
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-strahlentherapie-boost-sct: ConceptMap.group[0].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10870
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ConceptMap#cmd-0"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: cmd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))' (defined in http://hl7.org/fhir/StructureDefinition/ConceptMap)"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-strahlentherapie-boost-sct: ConceptMap"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-strahlentherapie-strahlenart-sct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-strahlentherapie-strahlenart-sct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 440
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-strahlentherapie-strahlenart-sct: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17464
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-strahlentherapie-strahlenart-sct: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17991
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-strahlentherapie-strahlenart-sct: ConceptMap.source.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18064
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-strahlentherapie-strahlenart-sct: ConceptMap.target.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18271
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-strahlentherapie-strahlenart-sct: ConceptMap.group[0].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21584
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ConceptMap#cmd-0"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: cmd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))' (defined in http://hl7.org/fhir/StructureDefinition/ConceptMap)"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-strahlentherapie-strahlenart-sct: ConceptMap"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-strahlentherapie-strahleneinheit-sct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-strahlentherapie-strahleneinheit-sct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 444
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-strahlentherapie-strahleneinheit-sct: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8754
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-strahlentherapie-strahleneinheit-sct: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9281
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-strahlentherapie-strahleneinheit-sct: ConceptMap.source.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9354
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-strahlentherapie-strahleneinheit-sct: ConceptMap.target.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9471
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-strahlentherapie-strahleneinheit-sct: ConceptMap.group[0].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10011
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ConceptMap#cmd-0"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: cmd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))' (defined in http://hl7.org/fhir/StructureDefinition/ConceptMap)"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-strahlentherapie-strahleneinheit-sct: ConceptMap"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10009
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_INCOMPLETE"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "Source Code System http://unitsofmeasure.org doesn't have all content (content = not-present), so the source codes cannot be checked"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-strahlentherapie-strahleneinheit-sct: ConceptMap.group[0].source"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-strahlentherapie-zielgebiet-sct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-strahlentherapie-zielgebiet-sct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 439
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-strahlentherapie-zielgebiet-sct: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62129
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-strahlentherapie-zielgebiet-sct: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62656
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-strahlentherapie-zielgebiet-sct: ConceptMap.source.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62729
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-strahlentherapie-zielgebiet-sct: ConceptMap.target.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62935
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-strahlentherapie-zielgebiet-sct: ConceptMap.group[0].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 80241
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ConceptMap#cmd-0"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: cmd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))' (defined in http://hl7.org/fhir/StructureDefinition/ConceptMap)"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-strahlentherapie-zielgebiet-sct: ConceptMap"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-studienteilnahme-sct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-studienteilnahme-sct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 428
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-studienteilnahme-sct: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8069
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-studienteilnahme-sct: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8596
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-studienteilnahme-sct: ConceptMap.source.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8669
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-studienteilnahme-sct: ConceptMap.target.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8864
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-studienteilnahme-sct: ConceptMap.group[0].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9254
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ConceptMap#cmd-0"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: cmd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))' (defined in http://hl7.org/fhir/StructureDefinition/ConceptMap)"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-studienteilnahme-sct: ConceptMap"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-therapie-ende-sct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-therapie-ende-sct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 425
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-therapie-ende-sct: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11942
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-therapie-ende-sct: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12469
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-therapie-ende-sct: ConceptMap.source.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12542
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-therapie-ende-sct: ConceptMap.target.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12665
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-therapie-grund-ende'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-therapie-ende-sct: ConceptMap.group[0].source"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12735
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-therapie-ende-sct: ConceptMap.group[0].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14094
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_String_WS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "value should not start or finish with whitespace ' Procedure declined by parent (situation)'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-therapie-ende-sct: ConceptMap.group[0].element[6].target[0].display"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14508
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ConceptMap#cmd-0"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: cmd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))' (defined in http://hl7.org/fhir/StructureDefinition/ConceptMap)"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-therapie-ende-sct: ConceptMap"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-therapie-stellung-sct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-therapie-stellung-sct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 429
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-therapie-stellung-sct: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9398
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-therapie-stellung-sct: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9925
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-therapie-stellung-sct: ConceptMap.source.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9998
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-therapie-stellung-sct: ConceptMap.target.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10199
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-therapie-stellung-sct: ConceptMap.group[0].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11005
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ConceptMap#cmd-0"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: cmd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))' (defined in http://hl7.org/fhir/StructureDefinition/ConceptMap)"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-therapie-stellung-sct: ConceptMap"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-therapie-typ-sct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-therapie-typ-sct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 424
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-therapie-typ-sct: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17087
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-therapie-typ-sct: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17614
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-therapie-typ-sct: ConceptMap.source.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17687
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-therapie-typ-sct: ConceptMap.target.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17878
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-therapie-typ-sct: ConceptMap.group[0].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21170
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ConceptMap#cmd-0"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: cmd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))' (defined in http://hl7.org/fhir/StructureDefinition/ConceptMap)"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-therapie-typ-sct: ConceptMap"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-therapieabweichung-sct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-therapieabweichung-sct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 430
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-therapieabweichung-sct: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8093
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-therapieabweichung-sct: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8620
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-therapieabweichung-sct: ConceptMap.source.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8693
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-therapieabweichung-sct: ConceptMap.target.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8890
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-therapieabweichung-sct: ConceptMap.group[0].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9280
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ConceptMap#cmd-0"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: cmd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))' (defined in http://hl7.org/fhir/StructureDefinition/ConceptMap)"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-therapieabweichung-sct: ConceptMap"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-therapieplanung-sct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-therapieplanung-sct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 427
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-therapieplanung-sct: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8865
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-therapieplanung-sct: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9392
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-therapieplanung-sct: ConceptMap.source.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9465
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-therapieplanung-sct: ConceptMap.target.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9663
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-therapieplanung-sct: ConceptMap.group[0].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10426
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ConceptMap#cmd-0"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: cmd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))' (defined in http://hl7.org/fhir/StructureDefinition/ConceptMap)"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-therapieplanung-sct: ConceptMap"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-tnm-uicc-sct-clinical",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-tnm-uicc-sct-clinical",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 429
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-clinical: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63706
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-clinical: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64215
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-clinical: ConceptMap.group[0].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 82574
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ConceptMap#cmd-0"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: cmd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))' (defined in http://hl7.org/fhir/StructureDefinition/ConceptMap)"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-clinical: ConceptMap"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 82572
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_TARGET_UNKNOWN"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "The Target Code System http://snomed.info/sct/900000000000207008/version/20240401 is not fully defined and populated, and no targetScope is specified, so the target code checking will not be performed"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-clinical: ConceptMap.group[0].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69397
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display 'T2c2' for the code 'https://www.uicc.org/resources/tnm|2027.0.0-ballot.1#T2c' is not valid. Possible displays: 'T2c'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-clinical: ConceptMap.group[0].element[34].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70385
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display 'Td3' for the code 'https://www.uicc.org/resources/tnm|2027.0.0-ballot.1#T3d' is not valid. Possible displays: 'T3d'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-clinical: ConceptMap.group[0].element[40].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71700
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display 'm' for the code 'https://www.uicc.org/resources/tnm|2027.0.0-ballot.1#m' is not valid. Possible displays: '(m)'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-clinical: ConceptMap.group[0].element[48].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71766
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display '2' for the code 'https://www.uicc.org/resources/tnm|2027.0.0-ballot.1#2' is not valid. Possible displays: '(2)'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-clinical: ConceptMap.group[0].element[49].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71832
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display '3' for the code 'https://www.uicc.org/resources/tnm|2027.0.0-ballot.1#3' is not valid. Possible displays: '(3)'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-clinical: ConceptMap.group[0].element[50].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71898
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display '4' for the code 'https://www.uicc.org/resources/tnm|2027.0.0-ballot.1#4' is not valid. Possible displays: '(4)'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-clinical: ConceptMap.group[0].element[51].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71964
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display '5' for the code 'https://www.uicc.org/resources/tnm|2027.0.0-ballot.1#5' is not valid. Possible displays: '(5)'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-clinical: ConceptMap.group[0].element[52].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72030
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display '6' for the code 'https://www.uicc.org/resources/tnm|2027.0.0-ballot.1#6' is not valid. Possible displays: '(6)'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-clinical: ConceptMap.group[0].element[53].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72096
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display '7' for the code 'https://www.uicc.org/resources/tnm|2027.0.0-ballot.1#7' is not valid. Possible displays: '(7)'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-clinical: ConceptMap.group[0].element[54].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display '8' for the code 'https://www.uicc.org/resources/tnm|2027.0.0-ballot.1#8' is not valid. Possible displays: '(8)'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-clinical: ConceptMap.group[0].element[55].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72228
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display '9' for the code 'https://www.uicc.org/resources/tnm|2027.0.0-ballot.1#9' is not valid. Possible displays: '(9)'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-clinical: ConceptMap.group[0].element[56].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display '10' for the code 'https://www.uicc.org/resources/tnm|2027.0.0-ballot.1#10' is not valid. Possible displays: '(10)'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-clinical: ConceptMap.group[0].element[57].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75784
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display 'i+' for the code 'https://www.uicc.org/resources/tnm|2027.0.0-ballot.1#i+' is not valid. Possible displays: '(i+)'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-clinical: ConceptMap.group[0].element[80].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display 'i-' for the code 'https://www.uicc.org/resources/tnm|2027.0.0-ballot.1#i-' is not valid. Possible displays: '(i-)'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-clinical: ConceptMap.group[0].element[81].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75922
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display 'mol+' for the code 'https://www.uicc.org/resources/tnm|2027.0.0-ballot.1#mol+' is not valid. Possible displays: '(mol+)'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-clinical: ConceptMap.group[0].element[82].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75994
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display 'mol-' for the code 'https://www.uicc.org/resources/tnm|2027.0.0-ballot.1#mol-' is not valid. Possible displays: '(mol-)'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-clinical: ConceptMap.group[0].element[83].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 76064
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display 'sn' for the code 'https://www.uicc.org/resources/tnm|2027.0.0-ballot.1#sn' is not valid. Possible displays: '(sn)'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-clinical: ConceptMap.group[0].element[84].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-tnm-uicc-sct-pathological",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-tnm-uicc-sct-pathological",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 433
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-pathological: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63413
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-pathological: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63922
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-pathological: ConceptMap.group[0].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 82188
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ConceptMap#cmd-0"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: cmd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))' (defined in http://hl7.org/fhir/StructureDefinition/ConceptMap)"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-pathological: ConceptMap"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 82186
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_TARGET_UNKNOWN"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "The Target Code System http://snomed.info/sct/900000000000207008/version/20240401 is not fully defined and populated, and no targetScope is specified, so the target code checking will not be performed"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-pathological: ConceptMap.group[0].target"
            ]
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          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69104
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display 'T2c2' for the code 'https://www.uicc.org/resources/tnm|2027.0.0-ballot.1#T2c' is not valid. Possible displays: 'T2c'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-pathological: ConceptMap.group[0].element[34].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70092
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display 'Td3' for the code 'https://www.uicc.org/resources/tnm|2027.0.0-ballot.1#T3d' is not valid. Possible displays: 'T3d'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-pathological: ConceptMap.group[0].element[40].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71312
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display 'm' for the code 'https://www.uicc.org/resources/tnm|2027.0.0-ballot.1#m' is not valid. Possible displays: '(m)'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-pathological: ConceptMap.group[0].element[48].code"
            ]
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          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71378
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display '2' for the code 'https://www.uicc.org/resources/tnm|2027.0.0-ballot.1#2' is not valid. Possible displays: '(2)'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-pathological: ConceptMap.group[0].element[49].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display '3' for the code 'https://www.uicc.org/resources/tnm|2027.0.0-ballot.1#3' is not valid. Possible displays: '(3)'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-pathological: ConceptMap.group[0].element[50].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display '4' for the code 'https://www.uicc.org/resources/tnm|2027.0.0-ballot.1#4' is not valid. Possible displays: '(4)'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-pathological: ConceptMap.group[0].element[51].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71576
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display '5' for the code 'https://www.uicc.org/resources/tnm|2027.0.0-ballot.1#5' is not valid. Possible displays: '(5)'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-pathological: ConceptMap.group[0].element[52].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display '6' for the code 'https://www.uicc.org/resources/tnm|2027.0.0-ballot.1#6' is not valid. Possible displays: '(6)'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-pathological: ConceptMap.group[0].element[53].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71708
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display '7' for the code 'https://www.uicc.org/resources/tnm|2027.0.0-ballot.1#7' is not valid. Possible displays: '(7)'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-pathological: ConceptMap.group[0].element[54].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71774
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display '8' for the code 'https://www.uicc.org/resources/tnm|2027.0.0-ballot.1#8' is not valid. Possible displays: '(8)'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-pathological: ConceptMap.group[0].element[55].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71840
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display '9' for the code 'https://www.uicc.org/resources/tnm|2027.0.0-ballot.1#9' is not valid. Possible displays: '(9)'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-pathological: ConceptMap.group[0].element[56].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71907
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display '10' for the code 'https://www.uicc.org/resources/tnm|2027.0.0-ballot.1#10' is not valid. Possible displays: '(10)'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-pathological: ConceptMap.group[0].element[57].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75398
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display 'i+' for the code 'https://www.uicc.org/resources/tnm|2027.0.0-ballot.1#i+' is not valid. Possible displays: '(i+)'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-pathological: ConceptMap.group[0].element[80].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75466
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display 'i-' for the code 'https://www.uicc.org/resources/tnm|2027.0.0-ballot.1#i-' is not valid. Possible displays: '(i-)'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-pathological: ConceptMap.group[0].element[81].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75536
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display 'mol+' for the code 'https://www.uicc.org/resources/tnm|2027.0.0-ballot.1#mol+' is not valid. Possible displays: '(mol+)'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-pathological: ConceptMap.group[0].element[82].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75608
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display 'mol-' for the code 'https://www.uicc.org/resources/tnm|2027.0.0-ballot.1#mol-' is not valid. Possible displays: '(mol-)'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-pathological: ConceptMap.group[0].element[83].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75678
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display 'sn' for the code 'https://www.uicc.org/resources/tnm|2027.0.0-ballot.1#sn' is not valid. Possible displays: '(sn)'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tnm-uicc-sct-pathological: ConceptMap.group[0].element[84].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-tod-sct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-tod-sct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 415
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tod-sct: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8357
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tod-sct: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8884
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tod-sct: ConceptMap.source.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8957
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tod-sct: ConceptMap.target.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9139
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tod-sct: ConceptMap.group[0].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9774
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ConceptMap#cmd-0"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: cmd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))' (defined in http://hl7.org/fhir/StructureDefinition/ConceptMap)"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-tod-sct: ConceptMap"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-verlauf-fernmetastasen-sct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-verlauf-fernmetastasen-sct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 434
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-verlauf-fernmetastasen-sct: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11584
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-verlauf-fernmetastasen-sct: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12111
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-verlauf-fernmetastasen-sct: ConceptMap.source.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12184
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-verlauf-fernmetastasen-sct: ConceptMap.target.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12385
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-verlauf-fernmetastasen-sct: ConceptMap.group[0].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 13815
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ConceptMap#cmd-0"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: cmd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))' (defined in http://hl7.org/fhir/StructureDefinition/ConceptMap)"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-verlauf-fernmetastasen-sct: ConceptMap"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12408
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "CONCEPTMAP_GROUP_SOURCE_DISPLAY_INVALID"
              }
            ],
            "severity": "warning",
            "code": "required",
            "details": {
              "text": "The source display 'kein Fernmetastasen nachweisbar' for the code 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-verlauf-fernmetastasen|2027.0.0-ballot.1#K' is not valid. Possible displays: 'keine Fernmetastasen nachweisbar'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-verlauf-fernmetastasen-sct: ConceptMap.group[0].element[0].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-verlauf-gesamtbeurteilung-sct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-verlauf-gesamtbeurteilung-sct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 437
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-verlauf-gesamtbeurteilung-sct: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12529
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-verlauf-gesamtbeurteilung-sct: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 13056
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-verlauf-gesamtbeurteilung-sct: ConceptMap.source.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 13129
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-verlauf-gesamtbeurteilung-sct: ConceptMap.target.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 13333
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-verlauf-gesamtbeurteilung-sct: ConceptMap.group[0].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15144
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ConceptMap#cmd-0"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: cmd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))' (defined in http://hl7.org/fhir/StructureDefinition/ConceptMap)"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-verlauf-gesamtbeurteilung-sct: ConceptMap"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-verlauf-lymphknoten-sct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-verlauf-lymphknoten-sct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 431
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-verlauf-lymphknoten-sct: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10919
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-verlauf-lymphknoten-sct: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11446
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-verlauf-lymphknoten-sct: ConceptMap.source.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11519
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-verlauf-lymphknoten-sct: ConceptMap.target.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11717
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-verlauf-lymphknoten-sct: ConceptMap.group[0].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12992
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ConceptMap#cmd-0"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: cmd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))' (defined in http://hl7.org/fhir/StructureDefinition/ConceptMap)"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-verlauf-lymphknoten-sct: ConceptMap"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onko-verlauf-primaertumor-sct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onko-verlauf-primaertumor-sct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 432
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-verlauf-primaertumor-sct: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10840
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-verlauf-primaertumor-sct: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11367
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-verlauf-primaertumor-sct: ConceptMap.source.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11440
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-verlauf-primaertumor-sct: ConceptMap.target.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11639
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://snomed.info/sct/900000000000207008/version/20240401'"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-verlauf-primaertumor-sct: ConceptMap.group[0].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12864
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ConceptMap#cmd-0"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: cmd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))' (defined in http://hl7.org/fhir/StructureDefinition/ConceptMap)"
            },
            "expression": [
              "ConceptMap/mii-cm-onko-verlauf-primaertumor-sct: ConceptMap"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ConceptMap-mii-cm-onkologie-to-mvgenomseq",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ConceptMap-mii-cm-onkologie-to-mvgenomseq",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 426
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ConceptMap/mii-cm-onkologie-to-mvgenomseq: ConceptMap.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19433
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ConceptMap/mii-cm-onkologie-to-mvgenomseq: ConceptMap.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19782
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onkologie/'"
            },
            "expression": [
              "ConceptMap/mii-cm-onkologie-to-mvgenomseq: ConceptMap.source.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19873
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.bfarm.de/DE/Das-BfArM/Aufgaben/Modellvorhaben-Genomsequenzierung'"
            },
            "expression": [
              "ConceptMap/mii-cm-onkologie-to-mvgenomseq: ConceptMap.target.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20126
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://github.com/BfArM-MVH/MVGenomseq_KDK/blob/main/KDK/OncologyCase.json'"
            },
            "expression": [
              "ConceptMap/mii-cm-onkologie-to-mvgenomseq: ConceptMap.group[0].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21363
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-diagnose/StructureDefinition/Diagnose'"
            },
            "expression": [
              "ConceptMap/mii-cm-onkologie-to-mvgenomseq: ConceptMap.group[1].source"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21477
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://github.com/BfArM-MVH/MVGenomseq_KDK/blob/main/KDK/OncologyCase.json'"
            },
            "expression": [
              "ConceptMap/mii-cm-onkologie-to-mvgenomseq: ConceptMap.group[1].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 22664
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://github.com/BfArM-MVH/MVGenomseq_KDK/blob/main/KDK/OncologyCase.json'"
            },
            "expression": [
              "ConceptMap/mii-cm-onkologie-to-mvgenomseq: ConceptMap.group[2].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 23147
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://github.com/BfArM-MVH/MVGenomseq_KDK/blob/main/KDK/OncologyCase.json'"
            },
            "expression": [
              "ConceptMap/mii-cm-onkologie-to-mvgenomseq: ConceptMap.group[3].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 23620
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableconceptmap|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://github.com/BfArM-MVH/MVGenomseq_KDK/blob/main/KDK/OncologyCase.json'"
            },
            "expression": [
              "ConceptMap/mii-cm-onkologie-to-mvgenomseq: ConceptMap.group[4].target"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 24134
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "A equivalent relationship has already been defined from the code Observation.valueCodeableConcept.coding.code to the code diagnosisOD.ECOGPerformanceStatusScore, but this defines a new relationship equivalent"
            },
            "expression": [
              "ConceptMap/mii-cm-onkologie-to-mvgenomseq: ConceptMap.group[4].element[1].target[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 24336
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "A equivalent relationship has already been defined from the code Observation.valueCodeableConcept.coding.code to the code diagnosisOD.ECOGPerformanceStatusScore, but this defines a new relationship equivalent"
            },
            "expression": [
              "ConceptMap/mii-cm-onkologie-to-mvgenomseq: ConceptMap.group[4].element[2].target[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 24538
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "A equivalent relationship has already been defined from the code Observation.valueCodeableConcept.coding.code to the code diagnosisOD.ECOGPerformanceStatusScore, but this defines a new relationship equivalent"
            },
            "expression": [
              "ConceptMap/mii-cm-onkologie-to-mvgenomseq: ConceptMap.group[4].element[3].target[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Condition-PatientKimMusterperson-Diagnosis-1",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-PatientKimMusterperson-Diagnosis-1",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 69
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor#onko-icd-meldepflicht"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: onko-icd-meldepflicht: 'Der ICD-10-GM-Code sollte aus der Menge der krebsregister-meldepflichtigen Neubildungen stammen (C00-C97, D00-D09, D32-D33, D35.2-D35.4, D37-D48). Andere Codes sind zulässig, aber untypisch für eine onkologische Primärdiagnose. ($this.memberOf('https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-icd10-meldepflichtige-tumoren'))' (defined in https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor)"
            },
            "expression": [
              "Condition/PatientKimMusterperson-Diagnosis-1: Condition.code.coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 42
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://terminology.hl7.org/CodeSystem/icd-o-3#C56.9 ('Ovar')'' in ValueSet."
            },
            "expression": [
              "Condition/PatientKimMusterperson-Diagnosis-1: Condition.bodySite[0].coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 42
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://terminology.hl7.org/CodeSystem/icd-o-3#C56.9 ('Ovar')'' in ValueSet."
            },
            "expression": [
              "Condition/PatientKimMusterperson-Diagnosis-1: Condition.bodySite[0].coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Condition-PatientKimMusterperson-PrimaryDiagnosis-2",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-PatientKimMusterperson-PrimaryDiagnosis-2",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 68
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor#onko-icd-meldepflicht"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: onko-icd-meldepflicht: 'Der ICD-10-GM-Code sollte aus der Menge der krebsregister-meldepflichtigen Neubildungen stammen (C00-C97, D00-D09, D32-D33, D35.2-D35.4, D37-D48). Andere Codes sind zulässig, aber untypisch für eine onkologische Primärdiagnose. ($this.memberOf('https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-icd10-meldepflichtige-tumoren'))' (defined in https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor)"
            },
            "expression": [
              "Condition/PatientKimMusterperson-PrimaryDiagnosis-2: Condition.code.coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 41
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://terminology.hl7.org/CodeSystem/icd-o-3#C56.9 ('Ovar')'' in ValueSet."
            },
            "expression": [
              "Condition/PatientKimMusterperson-PrimaryDiagnosis-2: Condition.bodySite[0].coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 41
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://terminology.hl7.org/CodeSystem/icd-o-3#C56.9 ('Ovar')'' in ValueSet."
            },
            "expression": [
              "Condition/PatientKimMusterperson-PrimaryDiagnosis-2: Condition.bodySite[0].coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Condition-mii-exa-onko-ascending-colon-cancer-diagnosis",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-onko-ascending-colon-cancer-diagnosis",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Display_Name_for__should_be_one_of__instead_of"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Wrong Display Name 'Neoplastic disease' for http://terminology.hl7.org/CodeSystem/condition-category#encounter-diagnosis. Valid display is 'Encounter Diagnosis' (for the language(s) 'en')"
            },
            "expression": [
              "Condition/mii-exa-onko-ascending-colon-cancer-diagnosis: Condition.category[0].coding[0].display"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 37
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor#onko-icd-meldepflicht"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: onko-icd-meldepflicht: 'Der ICD-10-GM-Code sollte aus der Menge der krebsregister-meldepflichtigen Neubildungen stammen (C00-C97, D00-D09, D32-D33, D35.2-D35.4, D37-D48). Andere Codes sind zulässig, aber untypisch für eine onkologische Primärdiagnose. ($this.memberOf('https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-icd10-meldepflichtige-tumoren'))' (defined in https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor)"
            },
            "expression": [
              "Condition/mii-exa-onko-ascending-colon-cancer-diagnosis: Condition.code.coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Condition-mii-exa-onko-colorectal-cancer-diagnosis",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-onko-colorectal-cancer-diagnosis",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 37
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor#onko-icd-meldepflicht"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: onko-icd-meldepflicht: 'Der ICD-10-GM-Code sollte aus der Menge der krebsregister-meldepflichtigen Neubildungen stammen (C00-C97, D00-D09, D32-D33, D35.2-D35.4, D37-D48). Andere Codes sind zulässig, aber untypisch für eine onkologische Primärdiagnose. ($this.memberOf('https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-icd10-meldepflichtige-tumoren'))' (defined in https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor)"
            },
            "expression": [
              "Condition/mii-exa-onko-colorectal-cancer-diagnosis: Condition.code.coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Condition-mii-exa-onko-cup-diagnose-aufgeloest",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-onko-cup-diagnose-aufgeloest",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 65
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://terminology.hl7.org/CodeSystem/icd-o-3#C25.9 ('Pankreas o.n.A.')'' in ValueSet."
            },
            "expression": [
              "Condition/mii-exa-onko-cup-diagnose-aufgeloest: Condition.bodySite[0].coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 65
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://terminology.hl7.org/CodeSystem/icd-o-3#C25.9 ('Pankreas o.n.A.')'' in ValueSet."
            },
            "expression": [
              "Condition/mii-exa-onko-cup-diagnose-aufgeloest: Condition.bodySite[0].coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Condition-mii-exa-onko-cup-diagnose",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-onko-cup-diagnose",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 65
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://terminology.hl7.org/CodeSystem/icd-o-3#C80.9 ('Unbekannte Primärlokalisation')'' in ValueSet."
            },
            "expression": [
              "Condition/mii-exa-onko-cup-diagnose: Condition.bodySite[0].coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 65
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://terminology.hl7.org/CodeSystem/icd-o-3#C80.9 ('Unbekannte Primärlokalisation')'' in ValueSet."
            },
            "expression": [
              "Condition/mii-exa-onko-cup-diagnose: Condition.bodySite[0].coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Condition-mii-exa-onko-diagnose-aml-transformation",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-onko-diagnose-aml-transformation",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 26
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Display_Name_for__should_be_one_of__instead_of"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Wrong Display Name 'Akute myeloische Leukämie mit myelodysplasieassoziierten Veränderungen' for http://terminology.hl7.org/CodeSystem/icd-o-3#9895/3. Valid display is 'Akute myeloische Leukämie mit Myelodysplasie-ähnlichen Veränderungen' (for the language(s) 'en')"
            },
            "expression": [
              "Condition/mii-exa-onko-diagnose-aml-transformation: Condition.extension[1].value.ofType(CodeableConcept).coding[0].display"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 26
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_TX_NoValid_1_CC"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "None of the codings provided are in the value set 'MII VS Onkologie ICD-O-3 Morphologie' (https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-icdo3-morphologie|2027.0.0-ballot.1), and a coding from this value set is required) (codes = http://terminology.hl7.org/CodeSystem/icd-o-3#9895/3)"
            },
            "expression": [
              "Condition/mii-exa-onko-diagnose-aml-transformation: Condition.extension[1].value.ofType(CodeableConcept)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 53
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor#onko-icd-meldepflicht"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: onko-icd-meldepflicht: 'Der ICD-10-GM-Code sollte aus der Menge der krebsregister-meldepflichtigen Neubildungen stammen (C00-C97, D00-D09, D32-D33, D35.2-D35.4, D37-D48). Andere Codes sind zulässig, aber untypisch für eine onkologische Primärdiagnose. ($this.memberOf('https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-icd10-meldepflichtige-tumoren'))' (defined in https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor)"
            },
            "expression": [
              "Condition/mii-exa-onko-diagnose-aml-transformation: Condition.code.coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 77
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://terminology.hl7.org/CodeSystem/icd-o-3#C42.1 ('Knochenmark')'' in ValueSet."
            },
            "expression": [
              "Condition/mii-exa-onko-diagnose-aml-transformation: Condition.bodySite[0].coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 77
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://terminology.hl7.org/CodeSystem/icd-o-3#C42.1 ('Knochenmark')'' in ValueSet."
            },
            "expression": [
              "Condition/mii-exa-onko-diagnose-aml-transformation: Condition.bodySite[0].coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Condition-mii-exa-onko-diagnose-angiosarkom-nach-radiatio",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-onko-diagnose-angiosarkom-nach-radiatio",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 69
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Display_Name_for__should_be_one_of__instead_of"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Wrong Display Name 'Bindegewebe des Thorax' for http://terminology.hl7.org/CodeSystem/icd-o-3#C49.3. Valid display is 'Bindegewebe, Subkutangewebe und sonstige Weichteile des Thorax' (for the language(s) 'en')"
            },
            "expression": [
              "Condition/mii-exa-onko-diagnose-angiosarkom-nach-radiatio: Condition.bodySite[0].coding[0].display"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 71
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://terminology.hl7.org/CodeSystem/icd-o-3#C49.3 ('Bindegewebe des Thorax')'' in ValueSet."
            },
            "expression": [
              "Condition/mii-exa-onko-diagnose-angiosarkom-nach-radiatio: Condition.bodySite[0].coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 71
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_TX_Confirm_4a"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "The code provided (http://terminology.hl7.org/CodeSystem/icd-o-3#C49.3) was not found in the value set 'MII VS Onkologie ICD-O-3 Topographie' (https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-icdo3-topographie|2027.0.0-ballot.1), and a code from this value set is required: Got multiple matches for ''http://terminology.hl7.org/CodeSystem/icd-o-3#C49.3 ('Bindegewebe des Thorax')'' in ValueSet.; Wrong Display Name 'Bindegewebe des Thorax' for http://terminology.hl7.org/CodeSystem/icd-o-3#C49.3. Valid display is 'Bindegewebe, Subkutangewebe und sonstige Weichteile des Thorax' (for the language(s) 'en'); Wrong Display Name 'Bindegewebe des Thorax' for http://terminology.hl7.org/CodeSystem/icd-o-3#C49.3. Valid display is 'Bindegewebe, Subkutangewebe und sonstige Weichteile des Thorax' (for the language(s) 'en')"
            },
            "expression": [
              "Condition/mii-exa-onko-diagnose-angiosarkom-nach-radiatio: Condition.bodySite[0].coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Condition-mii-exa-onko-diagnose-mds",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-onko-diagnose-mds",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 26
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Display_Name_for__should_be_one_of__instead_of"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Wrong Display Name 'Refraktäre Anämie mit Ringsideroblasten' for http://terminology.hl7.org/CodeSystem/icd-o-3#9983/3. Valid display is 'Myelodysplastisches Syndrom mit Blastenüberschuss' (for the language(s) 'en')"
            },
            "expression": [
              "Condition/mii-exa-onko-diagnose-mds: Condition.extension[1].value.ofType(CodeableConcept).coding[0].display"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 26
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_TX_NoValid_1_CC"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "None of the codings provided are in the value set 'MII VS Onkologie ICD-O-3 Morphologie' (https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-icdo3-morphologie|2027.0.0-ballot.1), and a coding from this value set is required) (codes = http://terminology.hl7.org/CodeSystem/icd-o-3#9983/3)"
            },
            "expression": [
              "Condition/mii-exa-onko-diagnose-mds: Condition.extension[1].value.ofType(CodeableConcept)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 39
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "NO_VALID_DISPLAY_FOUND_NONE_FOR_LANG_ERR"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Wrong Display Name 'Myelodysplastisches Syndrom: Refraktäre Anämie mit Ringsideroblasten' for http://fhir.de/CodeSystem/bfarm/icd-10-gm#D46.2. There are no valid display names found for language(s) 'en'. Default display is 'Refraktäre Anämie mit Blastenüberschuss [RAEB]'"
            },
            "expression": [
              "Condition/mii-exa-onko-diagnose-mds: Condition.code.coding[0].display"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 41
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor#onko-icd-meldepflicht"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: onko-icd-meldepflicht: 'Der ICD-10-GM-Code sollte aus der Menge der krebsregister-meldepflichtigen Neubildungen stammen (C00-C97, D00-D09, D32-D33, D35.2-D35.4, D37-D48). Andere Codes sind zulässig, aber untypisch für eine onkologische Primärdiagnose. ($this.memberOf('https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-icd10-meldepflichtige-tumoren'))' (defined in https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor)"
            },
            "expression": [
              "Condition/mii-exa-onko-diagnose-mds: Condition.code.coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 41
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_TX_Confirm_4a"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "The code provided (http://fhir.de/CodeSystem/bfarm/icd-10-gm#D46.2) was not found in the value set 'MII VS Diagnose ICD-10-GM' (https://www.medizininformatik-initiative.de/fhir/core/modul-diagnose/ValueSet/mii-vs-diagnose-icd10gm|2027.0.0-ballot), and a code from this value set is required: Wrong Display Name 'Myelodysplastisches Syndrom: Refraktäre Anämie mit Ringsideroblasten' for http://fhir.de/CodeSystem/bfarm/icd-10-gm#D46.2. There are no valid display names found for language(s) 'en'. Default display is 'Refraktäre Anämie mit Blastenüberschuss [RAEB]'"
            },
            "expression": [
              "Condition/mii-exa-onko-diagnose-mds: Condition.code.coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 65
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://terminology.hl7.org/CodeSystem/icd-o-3#C42.1 ('Knochenmark')'' in ValueSet."
            },
            "expression": [
              "Condition/mii-exa-onko-diagnose-mds: Condition.bodySite[0].coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 65
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://terminology.hl7.org/CodeSystem/icd-o-3#C42.1 ('Knochenmark')'' in ValueSet."
            },
            "expression": [
              "Condition/mii-exa-onko-diagnose-mds: Condition.bodySite[0].coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Condition-mii-exa-onko-diagnose-meningeom-benigne",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-onko-diagnose-meningeom-benigne",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 41
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor#onko-icd-meldepflicht"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: onko-icd-meldepflicht: 'Der ICD-10-GM-Code sollte aus der Menge der krebsregister-meldepflichtigen Neubildungen stammen (C00-C97, D00-D09, D32-D33, D35.2-D35.4, D37-D48). Andere Codes sind zulässig, aber untypisch für eine onkologische Primärdiagnose. ($this.memberOf('https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-icd10-meldepflichtige-tumoren'))' (defined in https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor)"
            },
            "expression": [
              "Condition/mii-exa-onko-diagnose-meningeom-benigne: Condition.code.coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 65
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://terminology.hl7.org/CodeSystem/icd-o-3#C70.0 ('Hirnhäute')'' in ValueSet."
            },
            "expression": [
              "Condition/mii-exa-onko-diagnose-meningeom-benigne: Condition.bodySite[0].coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 65
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://terminology.hl7.org/CodeSystem/icd-o-3#C70.0 ('Hirnhäute')'' in ValueSet."
            },
            "expression": [
              "Condition/mii-exa-onko-diagnose-meningeom-benigne: Condition.bodySite[0].coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Condition-mii-exa-onko-diagnose-meningeom-maligne-transformation",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-onko-diagnose-meningeom-maligne-transformation",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 71
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://terminology.hl7.org/CodeSystem/icd-o-3#C70.0 ('Hirnhäute')'' in ValueSet."
            },
            "expression": [
              "Condition/mii-exa-onko-diagnose-meningeom-maligne-transformation: Condition.bodySite[0].coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 71
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://terminology.hl7.org/CodeSystem/icd-o-3#C70.0 ('Hirnhäute')'' in ValueSet."
            },
            "expression": [
              "Condition/mii-exa-onko-diagnose-meningeom-maligne-transformation: Condition.bodySite[0].coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Condition-mii-exa-onko-diagnose-taml-nach-chemo",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-onko-diagnose-taml-nach-chemo",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 71
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://terminology.hl7.org/CodeSystem/icd-o-3#C42.1 ('Knochenmark')'' in ValueSet."
            },
            "expression": [
              "Condition/mii-exa-onko-diagnose-taml-nach-chemo: Condition.bodySite[0].coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 71
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://terminology.hl7.org/CodeSystem/icd-o-3#C42.1 ('Knochenmark')'' in ValueSet."
            },
            "expression": [
              "Condition/mii-exa-onko-diagnose-taml-nach-chemo: Condition.bodySite[0].coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Condition-mii-exa-onko-diagnose",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-onko-diagnose",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 26
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Display_Name_for__should_be_one_of__instead_of"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Wrong Display Name 'Infiltrating duct carcinoma, NOS' for http://terminology.hl7.org/CodeSystem/icd-o-3#8500/3. Valid display is 'Invasives duktales Karzinom o.n.A.' (for the language(s) 'en')"
            },
            "expression": [
              "Condition/mii-exa-onko-diagnose: Condition.extension[1].value.ofType(CodeableConcept).coding[0].display"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 26
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://terminology.hl7.org/CodeSystem/icd-o-3#8500/3 ('Infiltrating duct carcinoma, NOS')'' in ValueSet."
            },
            "expression": [
              "Condition/mii-exa-onko-diagnose: Condition.extension[1].value.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 26
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_TX_NoValid_1_CC"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "None of the codings provided are in the value set 'MII VS Onkologie ICD-O-3 Morphologie' (https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-icdo3-morphologie|2027.0.0-ballot.1), and a coding from this value set is required) (codes = http://terminology.hl7.org/CodeSystem/icd-o-3#8500/3)"
            },
            "expression": [
              "Condition/mii-exa-onko-diagnose: Condition.extension[1].value.ofType(CodeableConcept)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 41
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor#onko-icd-meldepflicht"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: onko-icd-meldepflicht: 'Der ICD-10-GM-Code sollte aus der Menge der krebsregister-meldepflichtigen Neubildungen stammen (C00-C97, D00-D09, D32-D33, D35.2-D35.4, D37-D48). Andere Codes sind zulässig, aber untypisch für eine onkologische Primärdiagnose. ($this.memberOf('https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-icd10-meldepflichtige-tumoren'))' (defined in https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor)"
            },
            "expression": [
              "Condition/mii-exa-onko-diagnose: Condition.code.coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 80
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://terminology.hl7.org/CodeSystem/icd-o-3#C50.4 ('Oberer äußerer Quadrant der Brust')'' in ValueSet."
            },
            "expression": [
              "Condition/mii-exa-onko-diagnose: Condition.bodySite[0].coding[1].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 80
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://terminology.hl7.org/CodeSystem/icd-o-3#C50.4 ('Oberer äußerer Quadrant der Brust')'' in ValueSet."
            },
            "expression": [
              "Condition/mii-exa-onko-diagnose: Condition.bodySite[0].coding[1]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Condition-mii-exa-onko-fruehere-tumorerkrankung-cervix",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-onko-fruehere-tumorerkrankung-cervix"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Condition-mii-exa-onko-fruehere-tumorerkrankung-freetext",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-onko-fruehere-tumorerkrankung-freetext"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Condition-mii-exa-onko-fruehere-tumorerkrankung-mamma",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-onko-fruehere-tumorerkrankung-mamma",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 43
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-fruehere-tumorerkrankung|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://terminology.hl7.org/CodeSystem/icd-o-3#C50.9 ('Brust o.n.A.')'' in ValueSet."
            },
            "expression": [
              "Condition/mii-exa-onko-fruehere-tumorerkrankung-mamma: Condition.bodySite[0].coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 43
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-fruehere-tumorerkrankung|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://terminology.hl7.org/CodeSystem/icd-o-3#C50.9 ('Brust o.n.A.')'' in ValueSet."
            },
            "expression": [
              "Condition/mii-exa-onko-fruehere-tumorerkrankung-mamma: Condition.bodySite[0].coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Condition-mii-exa-onko-fruehere-tumorerkrankung-prostata",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-onko-fruehere-tumorerkrankung-prostata",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 43
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-fruehere-tumorerkrankung|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://terminology.hl7.org/CodeSystem/icd-o-3#C61.9 ('Prostata')'' in ValueSet."
            },
            "expression": [
              "Condition/mii-exa-onko-fruehere-tumorerkrankung-prostata: Condition.bodySite[0].coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 43
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-fruehere-tumorerkrankung|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://terminology.hl7.org/CodeSystem/icd-o-3#C61.9 ('Prostata')'' in ValueSet."
            },
            "expression": [
              "Condition/mii-exa-onko-fruehere-tumorerkrankung-prostata: Condition.bodySite[0].coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Condition-mii-exa-onko-kim-synth-diagnose",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-onko-kim-synth-diagnose",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 28
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor#onko-icd-meldepflicht"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: onko-icd-meldepflicht: 'Der ICD-10-GM-Code sollte aus der Menge der krebsregister-meldepflichtigen Neubildungen stammen (C00-C97, D00-D09, D32-D33, D35.2-D35.4, D37-D48). Andere Codes sind zulässig, aber untypisch für eine onkologische Primärdiagnose. ($this.memberOf('https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-icd10-meldepflichtige-tumoren'))' (defined in https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor)"
            },
            "expression": [
              "Condition/mii-exa-onko-kim-synth-diagnose: Condition.code.coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Condition-mii-exa-onko-krk-diagnose",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-onko-krk-diagnose",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 44
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor#onko-icd-meldepflicht"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: onko-icd-meldepflicht: 'Der ICD-10-GM-Code sollte aus der Menge der krebsregister-meldepflichtigen Neubildungen stammen (C00-C97, D00-D09, D32-D33, D35.2-D35.4, D37-D48). Andere Codes sind zulässig, aber untypisch für eine onkologische Primärdiagnose. ($this.memberOf('https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-icd10-meldepflichtige-tumoren'))' (defined in https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor)"
            },
            "expression": [
              "Condition/mii-exa-onko-krk-diagnose: Condition.code.coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Condition-mii-exa-onko-mamma-diagnose",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-onko-mamma-diagnose",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 28
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor#onko-icd-meldepflicht"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: onko-icd-meldepflicht: 'Der ICD-10-GM-Code sollte aus der Menge der krebsregister-meldepflichtigen Neubildungen stammen (C00-C97, D00-D09, D32-D33, D35.2-D35.4, D37-D48). Andere Codes sind zulässig, aber untypisch für eine onkologische Primärdiagnose. ($this.memberOf('https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-icd10-meldepflichtige-tumoren'))' (defined in https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor)"
            },
            "expression": [
              "Condition/mii-exa-onko-mamma-diagnose: Condition.code.coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Condition-mii-exa-onko-melanom-diagnose",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-onko-melanom-diagnose",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 49
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor#onko-icd-meldepflicht"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: onko-icd-meldepflicht: 'Der ICD-10-GM-Code sollte aus der Menge der krebsregister-meldepflichtigen Neubildungen stammen (C00-C97, D00-D09, D32-D33, D35.2-D35.4, D37-D48). Andere Codes sind zulässig, aber untypisch für eine onkologische Primärdiagnose. ($this.memberOf('https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-icd10-meldepflichtige-tumoren'))' (defined in https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor)"
            },
            "expression": [
              "Condition/mii-exa-onko-melanom-diagnose: Condition.code.coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Condition-mii-exa-onko-prostata-diagnose",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-onko-prostata-diagnose",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 28
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor#onko-icd-meldepflicht"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: onko-icd-meldepflicht: 'Der ICD-10-GM-Code sollte aus der Menge der krebsregister-meldepflichtigen Neubildungen stammen (C00-C97, D00-D09, D32-D33, D35.2-D35.4, D37-D48). Andere Codes sind zulässig, aber untypisch für eine onkologische Primärdiagnose. ($this.memberOf('https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-icd10-meldepflichtige-tumoren'))' (defined in https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor)"
            },
            "expression": [
              "Condition/mii-exa-onko-prostata-diagnose: Condition.code.coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Condition-mii-exa-onko-tnm-bundle-diagnose",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-onko-tnm-bundle-diagnose",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 28
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor#onko-icd-meldepflicht"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: onko-icd-meldepflicht: 'Der ICD-10-GM-Code sollte aus der Menge der krebsregister-meldepflichtigen Neubildungen stammen (C00-C97, D00-D09, D32-D33, D35.2-D35.4, D37-D48). Andere Codes sind zulässig, aber untypisch für eine onkologische Primärdiagnose. ($this.memberOf('https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-icd10-meldepflichtige-tumoren'))' (defined in https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor)"
            },
            "expression": [
              "Condition/mii-exa-onko-tnm-bundle-diagnose: Condition.code.coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Condition-mii-exa-onko-tnm-bundle-legacy-diagnose",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-onko-tnm-bundle-legacy-diagnose",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 28
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor#onko-icd-meldepflicht"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: onko-icd-meldepflicht: 'Der ICD-10-GM-Code sollte aus der Menge der krebsregister-meldepflichtigen Neubildungen stammen (C00-C97, D00-D09, D32-D33, D35.2-D35.4, D37-D48). Andere Codes sind zulässig, aber untypisch für eine onkologische Primärdiagnose. ($this.memberOf('https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-icd10-meldepflichtige-tumoren'))' (defined in https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor)"
            },
            "expression": [
              "Condition/mii-exa-onko-tnm-bundle-legacy-diagnose: Condition.code.coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Condition-mii-exa-onko-tnm-synth-diagnose",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-mii-exa-onko-tnm-synth-diagnose",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 28
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor#onko-icd-meldepflicht"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: onko-icd-meldepflicht: 'Der ICD-10-GM-Code sollte aus der Menge der krebsregister-meldepflichtigen Neubildungen stammen (C00-C97, D00-D09, D32-D33, D35.2-D35.4, D37-D48). Andere Codes sind zulässig, aber untypisch für eine onkologische Primärdiagnose. ($this.memberOf('https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-icd10-meldepflichtige-tumoren'))' (defined in https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor)"
            },
            "expression": [
              "Condition/mii-exa-onko-tnm-synth-diagnose: Condition.code.coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Condition-primaertumor-example",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Condition-primaertumor-example",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 44
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor#onko-icd-meldepflicht"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: onko-icd-meldepflicht: 'Der ICD-10-GM-Code sollte aus der Menge der krebsregister-meldepflichtigen Neubildungen stammen (C00-C97, D00-D09, D32-D33, D35.2-D35.4, D37-D48). Andere Codes sind zulässig, aber untypisch für eine onkologische Primärdiagnose. ($this.memberOf('https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-icd10-meldepflichtige-tumoren'))' (defined in https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor)"
            },
            "expression": [
              "Condition/primaertumor-example: Condition.code.coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Device-mii-exa-onko-kim-synthesis-device",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Device-mii-exa-onko-kim-synthesis-device"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/DiagnosticReport-PatientKimMusterperson-PathoReport-1",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "DiagnosticReport-PatientKimMusterperson-PathoReport-1"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/DiagnosticReport-mii-exa-onko-befund-1",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "DiagnosticReport-mii-exa-onko-befund-1"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Encounter-example-chemo-phase1",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Encounter-example-chemo-phase1"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Encounter-example-chemo-phase2",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Encounter-example-chemo-phase2"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Encounter-example-diagnosis-modification",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Encounter-example-diagnosis-modification"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Encounter-example-surgery-modification",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Encounter-example-surgery-modification"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Encounter-example",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Encounter-example"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Encounter-mii-exa-onko-folfox-encounter-chemo",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Encounter-mii-exa-onko-folfox-encounter-chemo"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Encounter-mii-exa-onko-folfox-encounter-diagnosis",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Encounter-mii-exa-onko-folfox-encounter-diagnosis"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Encounter-mii-exa-onko-folfox-encounter-surgery",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Encounter-mii-exa-onko-folfox-encounter-surgery"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Encounter-mii-exa-onko-krk-bundle-encounter",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Encounter-mii-exa-onko-krk-bundle-encounter"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Encounter-mii-exa-onko-mamma-bundle-encounter",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Encounter-mii-exa-onko-mamma-bundle-encounter"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Encounter-mii-exa-onko-melanom-bundle-encounter",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Encounter-mii-exa-onko-melanom-bundle-encounter"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Encounter-mii-exa-onko-prostata-bundle-encounter",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Encounter-mii-exa-onko-prostata-bundle-encounter"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Library-mii-lib-onko-synthesize-tnm",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Library-mii-lib-onko-synthesize-tnm",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 420
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablelibrary|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "Library/mii-lib-onko-synthesize-tnm: Library.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2464
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablelibrary|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Library/mii-lib-onko-synthesize-tnm: Library.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 3690
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablelibrary|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://github.com/medizininformatik-initiative/kerndatensatzmodul-onkologie/blob/main/.claude/scripts/synthesize_tnm/README.md'"
            },
            "expression": [
              "Library/mii-lib-onko-synthesize-tnm: Library.relatedArtifact[0].url"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "Publisher"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "\"The narrative includes custom content for the default language (en), but does not include translated content for the de language, so the default language has been used"
            },
            "expression": [
              "IG"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/List-mii-exa-onko-liste-evidenz-erstdiagnose-1",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "List-mii-exa-onko-liste-evidenz-erstdiagnose-1"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/MedicationRequest-mii-exa-onko-cdk46-class-medication",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MedicationRequest-mii-exa-onko-cdk46-class-medication",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01EF ('Cyclin-abhängige Kinasen (CDK)-Inhibitoren')'' in ValueSet."
            },
            "expression": [
              "MedicationRequest/mii-exa-onko-cdk46-class-medication: MedicationRequest.medication.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01EF ('Cyclin-abhängige Kinasen (CDK)-Inhibitoren')'' in ValueSet."
            },
            "expression": [
              "MedicationRequest/mii-exa-onko-cdk46-class-medication: MedicationRequest.medication.ofType(CodeableConcept).coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/MedicationRequest-mii-exa-onko-folfox-5fu-request",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MedicationRequest-mii-exa-onko-folfox-5fu-request",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01BC02 ('Fluorouracil')'' in ValueSet."
            },
            "expression": [
              "MedicationRequest/mii-exa-onko-folfox-5fu-request: MedicationRequest.medication.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01BC02 ('Fluorouracil')'' in ValueSet."
            },
            "expression": [
              "MedicationRequest/mii-exa-onko-folfox-5fu-request: MedicationRequest.medication.ofType(CodeableConcept).coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/MedicationRequest-mii-exa-onko-folfox-leucovorin-request",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MedicationRequest-mii-exa-onko-folfox-leucovorin-request",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#V03AF03 ('Calciumfolinat')'' in ValueSet."
            },
            "expression": [
              "MedicationRequest/mii-exa-onko-folfox-leucovorin-request: MedicationRequest.medication.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#V03AF03 ('Calciumfolinat')'' in ValueSet."
            },
            "expression": [
              "MedicationRequest/mii-exa-onko-folfox-leucovorin-request: MedicationRequest.medication.ofType(CodeableConcept).coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/MedicationRequest-mii-exa-onko-folfox-oxaliplatin-request",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MedicationRequest-mii-exa-onko-folfox-oxaliplatin-request",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01XA03 ('Oxaliplatin')'' in ValueSet."
            },
            "expression": [
              "MedicationRequest/mii-exa-onko-folfox-oxaliplatin-request: MedicationRequest.medication.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01XA03 ('Oxaliplatin')'' in ValueSet."
            },
            "expression": [
              "MedicationRequest/mii-exa-onko-folfox-oxaliplatin-request: MedicationRequest.medication.ofType(CodeableConcept).coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/MedicationRequest-mii-exa-onko-modification-5fu-request",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MedicationRequest-mii-exa-onko-modification-5fu-request",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Validation_VAL_Profile_Minimum_SLICE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "Slice 'MedicationRequest.reasonReference:Primaertumor': a matching slice is required, but not found (from https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-therapieempfehlung-medikation|2027.0.0-ballot.1). Note that other slices are allowed in addition to this required slice"
            },
            "expression": [
              "MedicationRequest/mii-exa-onko-modification-5fu-request: MedicationRequest"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01BC02 ('Fluorouracil')'' in ValueSet."
            },
            "expression": [
              "MedicationRequest/mii-exa-onko-modification-5fu-request: MedicationRequest.medication.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01BC02 ('Fluorouracil')'' in ValueSet."
            },
            "expression": [
              "MedicationRequest/mii-exa-onko-modification-5fu-request: MedicationRequest.medication.ofType(CodeableConcept).coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/MedicationRequest-mii-exa-onko-modification-leucovorin-request",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MedicationRequest-mii-exa-onko-modification-leucovorin-request",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Validation_VAL_Profile_Minimum_SLICE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "Slice 'MedicationRequest.reasonReference:Primaertumor': a matching slice is required, but not found (from https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-therapieempfehlung-medikation|2027.0.0-ballot.1). Note that other slices are allowed in addition to this required slice"
            },
            "expression": [
              "MedicationRequest/mii-exa-onko-modification-leucovorin-request: MedicationRequest"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#V03AF03 ('Calciumfolinat')'' in ValueSet."
            },
            "expression": [
              "MedicationRequest/mii-exa-onko-modification-leucovorin-request: MedicationRequest.medication.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#V03AF03 ('Calciumfolinat')'' in ValueSet."
            },
            "expression": [
              "MedicationRequest/mii-exa-onko-modification-leucovorin-request: MedicationRequest.medication.ofType(CodeableConcept).coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/MedicationRequest-mii-exa-onko-modification-oxaliplatin-request",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MedicationRequest-mii-exa-onko-modification-oxaliplatin-request",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Validation_VAL_Profile_Minimum_SLICE"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "error",
            "code": "structure",
            "details": {
              "text": "Slice 'MedicationRequest.reasonReference:Primaertumor': a matching slice is required, but not found (from https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-therapieempfehlung-medikation|2027.0.0-ballot.1). Note that other slices are allowed in addition to this required slice"
            },
            "expression": [
              "MedicationRequest/mii-exa-onko-modification-oxaliplatin-request: MedicationRequest"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01XA03 ('Oxaliplatin')'' in ValueSet."
            },
            "expression": [
              "MedicationRequest/mii-exa-onko-modification-oxaliplatin-request: MedicationRequest.medication.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01XA03 ('Oxaliplatin')'' in ValueSet."
            },
            "expression": [
              "MedicationRequest/mii-exa-onko-modification-oxaliplatin-request: MedicationRequest.medication.ofType(CodeableConcept).coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/MedicationRequest-mii-exa-onko-tdm1-option",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MedicationRequest-mii-exa-onko-tdm1-option",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01FD03 ('Trastuzumab emtansin')'' in ValueSet."
            },
            "expression": [
              "MedicationRequest/mii-exa-onko-tdm1-option: MedicationRequest.medication.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01FD03 ('Trastuzumab emtansin')'' in ValueSet."
            },
            "expression": [
              "MedicationRequest/mii-exa-onko-tdm1-option: MedicationRequest.medication.ofType(CodeableConcept).coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/MedicationRequest-mii-exa-onko-tucatinib-option",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MedicationRequest-mii-exa-onko-tucatinib-option",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01EH03 ('Tucatinib')'' in ValueSet."
            },
            "expression": [
              "MedicationRequest/mii-exa-onko-tucatinib-option: MedicationRequest.medication.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01EH03 ('Tucatinib')'' in ValueSet."
            },
            "expression": [
              "MedicationRequest/mii-exa-onko-tucatinib-option: MedicationRequest.medication.ofType(CodeableConcept).coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/MedicationStatement-PatientKimMusterperson-SystemicTherapyMedication-1a",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MedicationStatement-PatientKimMusterperson-SystemicTherapyMedication-1a",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01CD01 ('Paclitaxel')'' in ValueSet."
            },
            "expression": [
              "MedicationStatement/PatientKimMusterperson-SystemicTherapyMedication-1a: MedicationStatement.medication.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01CD01 ('Paclitaxel')'' in ValueSet."
            },
            "expression": [
              "MedicationStatement/PatientKimMusterperson-SystemicTherapyMedication-1a: MedicationStatement.medication.ofType(CodeableConcept).coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/MedicationStatement-PatientKimMusterperson-SystemicTherapyMedication-1b",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MedicationStatement-PatientKimMusterperson-SystemicTherapyMedication-1b",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01XA02 ('Carboplatin')'' in ValueSet."
            },
            "expression": [
              "MedicationStatement/PatientKimMusterperson-SystemicTherapyMedication-1b: MedicationStatement.medication.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01XA02 ('Carboplatin')'' in ValueSet."
            },
            "expression": [
              "MedicationStatement/PatientKimMusterperson-SystemicTherapyMedication-1b: MedicationStatement.medication.ofType(CodeableConcept).coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/MedicationStatement-PatientKimMusterperson-SystemicTherapyMedication-2a",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MedicationStatement-PatientKimMusterperson-SystemicTherapyMedication-2a",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01BC05 ('Gemcitabin')'' in ValueSet."
            },
            "expression": [
              "MedicationStatement/PatientKimMusterperson-SystemicTherapyMedication-2a: MedicationStatement.medication.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01BC05 ('Gemcitabin')'' in ValueSet."
            },
            "expression": [
              "MedicationStatement/PatientKimMusterperson-SystemicTherapyMedication-2a: MedicationStatement.medication.ofType(CodeableConcept).coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/MedicationStatement-PatientKimMusterperson-SystemicTherapyMedication-2b",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MedicationStatement-PatientKimMusterperson-SystemicTherapyMedication-2b",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01XA02 ('Carboplatin')'' in ValueSet."
            },
            "expression": [
              "MedicationStatement/PatientKimMusterperson-SystemicTherapyMedication-2b: MedicationStatement.medication.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01XA02 ('Carboplatin')'' in ValueSet."
            },
            "expression": [
              "MedicationStatement/PatientKimMusterperson-SystemicTherapyMedication-2b: MedicationStatement.medication.ofType(CodeableConcept).coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/MedicationStatement-PatientKimMusterperson-SystemicTherapyMedication-3",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MedicationStatement-PatientKimMusterperson-SystemicTherapyMedication-3",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01XK02 ('Niraparib')'' in ValueSet."
            },
            "expression": [
              "MedicationStatement/PatientKimMusterperson-SystemicTherapyMedication-3: MedicationStatement.medication.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01XK02 ('Niraparib')'' in ValueSet."
            },
            "expression": [
              "MedicationStatement/PatientKimMusterperson-SystemicTherapyMedication-3: MedicationStatement.medication.ofType(CodeableConcept).coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/MedicationStatement-mii-exa-onko-folfox-5fu-statement",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MedicationStatement-mii-exa-onko-folfox-5fu-statement",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01BC02 ('Fluorouracil')'' in ValueSet."
            },
            "expression": [
              "MedicationStatement/mii-exa-onko-folfox-5fu-statement: MedicationStatement.medication.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01BC02 ('Fluorouracil')'' in ValueSet."
            },
            "expression": [
              "MedicationStatement/mii-exa-onko-folfox-5fu-statement: MedicationStatement.medication.ofType(CodeableConcept).coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/MedicationStatement-mii-exa-onko-folfox-leucovorin-statement",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MedicationStatement-mii-exa-onko-folfox-leucovorin-statement",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#V03AF03 ('Calciumfolinat')'' in ValueSet."
            },
            "expression": [
              "MedicationStatement/mii-exa-onko-folfox-leucovorin-statement: MedicationStatement.medication.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#V03AF03 ('Calciumfolinat')'' in ValueSet."
            },
            "expression": [
              "MedicationStatement/mii-exa-onko-folfox-leucovorin-statement: MedicationStatement.medication.ofType(CodeableConcept).coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/MedicationStatement-mii-exa-onko-folfox-oxaliplatin-statement",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MedicationStatement-mii-exa-onko-folfox-oxaliplatin-statement",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01XA03 ('Oxaliplatin')'' in ValueSet."
            },
            "expression": [
              "MedicationStatement/mii-exa-onko-folfox-oxaliplatin-statement: MedicationStatement.medication.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01XA03 ('Oxaliplatin')'' in ValueSet."
            },
            "expression": [
              "MedicationStatement/mii-exa-onko-folfox-oxaliplatin-statement: MedicationStatement.medication.ofType(CodeableConcept).coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/MedicationStatement-mii-exa-onko-medikation-iberdomide-unii",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MedicationStatement-mii-exa-onko-medikation-iberdomide-unii"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/MedicationStatement-mii-exa-onko-medikation-imatinib-atc-version-transition",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MedicationStatement-mii-exa-onko-medikation-imatinib-atc-version-transition"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/MedicationStatement-mii-exa-onko-modification-5fu-phase1",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MedicationStatement-mii-exa-onko-modification-5fu-phase1",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01BC02 ('Fluorouracil')'' in ValueSet."
            },
            "expression": [
              "MedicationStatement/mii-exa-onko-modification-5fu-phase1: MedicationStatement.medication.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01BC02 ('Fluorouracil')'' in ValueSet."
            },
            "expression": [
              "MedicationStatement/mii-exa-onko-modification-5fu-phase1: MedicationStatement.medication.ofType(CodeableConcept).coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/MedicationStatement-mii-exa-onko-modification-5fu-phase2",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MedicationStatement-mii-exa-onko-modification-5fu-phase2",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01BC02 ('Fluorouracil')'' in ValueSet."
            },
            "expression": [
              "MedicationStatement/mii-exa-onko-modification-5fu-phase2: MedicationStatement.medication.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01BC02 ('Fluorouracil')'' in ValueSet."
            },
            "expression": [
              "MedicationStatement/mii-exa-onko-modification-5fu-phase2: MedicationStatement.medication.ofType(CodeableConcept).coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/MedicationStatement-mii-exa-onko-modification-leucovorin-phase1",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MedicationStatement-mii-exa-onko-modification-leucovorin-phase1",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#V03AF03 ('Calciumfolinat')'' in ValueSet."
            },
            "expression": [
              "MedicationStatement/mii-exa-onko-modification-leucovorin-phase1: MedicationStatement.medication.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#V03AF03 ('Calciumfolinat')'' in ValueSet."
            },
            "expression": [
              "MedicationStatement/mii-exa-onko-modification-leucovorin-phase1: MedicationStatement.medication.ofType(CodeableConcept).coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/MedicationStatement-mii-exa-onko-modification-leucovorin-phase2",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MedicationStatement-mii-exa-onko-modification-leucovorin-phase2",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#V03AF03 ('Calciumfolinat')'' in ValueSet."
            },
            "expression": [
              "MedicationStatement/mii-exa-onko-modification-leucovorin-phase2: MedicationStatement.medication.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#V03AF03 ('Calciumfolinat')'' in ValueSet."
            },
            "expression": [
              "MedicationStatement/mii-exa-onko-modification-leucovorin-phase2: MedicationStatement.medication.ofType(CodeableConcept).coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/MedicationStatement-mii-exa-onko-modification-oxaliplatin-phase1",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MedicationStatement-mii-exa-onko-modification-oxaliplatin-phase1",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01XA03 ('Oxaliplatin')'' in ValueSet."
            },
            "expression": [
              "MedicationStatement/mii-exa-onko-modification-oxaliplatin-phase1: MedicationStatement.medication.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 11
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://fhir.de/CodeSystem/bfarm/atc#L01XA03 ('Oxaliplatin')'' in ValueSet."
            },
            "expression": [
              "MedicationStatement/mii-exa-onko-modification-oxaliplatin-phase1: MedicationStatement.medication.ofType(CodeableConcept).coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/MedicationStatement-mii-exa-onko-systemische-therapie-medikation1",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MedicationStatement-mii-exa-onko-systemische-therapie-medikation1"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/MedicationStatement-mii-exa-onko-systemische-therapie-medikation2",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "MedicationStatement-mii-exa-onko-systemische-therapie-medikation2"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-PatientKimMusterperson-Verlauf-2022-01-22",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-PatientKimMusterperson-Verlauf-2022-01-22",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/PatientKimMusterperson-Verlauf-2022-01-22: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-TNM-Klassifikation-Observation-2",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-TNM-Klassifikation-Observation-2",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/TNM-Klassifikation-Observation-2: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-TNM-L-Observation-2",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-TNM-L-Observation-2",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/TNM-L-Observation-2: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-TNM-M-Observation-2",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-TNM-M-Observation-2",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/TNM-M-Observation-2: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-TNM-Pn-Observation-2",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-TNM-Pn-Observation-2",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/TNM-Pn-Observation-2: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-TNM-T-Observation-2",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-TNM-T-Observation-2",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/TNM-T-Observation-2: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-TNM-V-Observation-2",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-TNM-V-Observation-2",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/TNM-V-Observation-2: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-TNM-y-Symbol-Observation-2",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-TNM-y-Symbol-Observation-2",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/TNM-y-Symbol-Observation-2: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-allgemeiner-leistungszustand-ecog",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-allgemeiner-leistungszustand-ecog",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 21
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-allgemeiner-leistungszustand-ecog|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-allgemeiner-leistungszustand-ecog' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Observation/mii-exa-onko-allgemeiner-leistungszustand-ecog: Observation.value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 21
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-allgemeiner-leistungszustand-ecog|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://loinc.org' version 'null' could not be found, so the code cannot be validated. Valid versions: [2.80, 2.81, 2.77, 2.78, 2.82, 2.83]"
            },
            "expression": [
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    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-colorectal-tnm-m",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-colorectal-tnm-m",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-colorectal-tnm-m: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-colorectal-tnm-n",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-colorectal-tnm-n",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-colorectal-tnm-n: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-colorectal-tnm-t",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-colorectal-tnm-t",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-colorectal-tnm-t: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-colorectal-tnm",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-colorectal-tnm",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-colorectal-tnm: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-cup-fernmetastase-hep",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-cup-fernmetastase-hep",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-cup-fernmetastase-hep: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-cup-fernmetastase-pul",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-cup-fernmetastase-pul",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-cup-fernmetastase-pul: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-cup-tnm-klassifikation",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-cup-tnm-klassifikation",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-cup-tnm-klassifikation: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-cup-tnm-m-cM1",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-cup-tnm-m-cM1",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-m-kategorie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Observation/mii-exa-onko-cup-tnm-m-cM1: Observation.value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-m-kategorie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Observation/mii-exa-onko-cup-tnm-m-cM1: Observation.value.ofType(CodeableConcept).coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-cup-tnm-m-cM1: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-cup-tnm-n-cNX",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-cup-tnm-n-cNX",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-cup-tnm-n-cNX: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-cup-tnm-t-cTX",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-cup-tnm-t-cTX",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-cup-tnm-t-cTX: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-fernmetastasen-1",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-fernmetastasen-1",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-fernmetastasen-1: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-folfox-verlauf-6months",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-folfox-verlauf-6months",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-folfox-verlauf-6months: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-genetische-variante-braf",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-genetische-variante-braf",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-genetische-variante-braf: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-grading-1",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-grading-1",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-grading-1: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-histologie-icdo3",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-histologie-icdo3",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 18
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Display_Name_for__should_be_one_of__instead_of"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-histologie-icdo3|2027.0.0-ballot.1"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Wrong Display Name 'Infiltrating duct carcinoma, NOS' for http://terminology.hl7.org/CodeSystem/icd-o-3#8500/3. Valid display is 'Invasives duktales Karzinom o.n.A.' (for the language(s) 'en')"
            },
            "expression": [
              "Observation/mii-exa-onko-histologie-icdo3: Observation.value.ofType(CodeableConcept).coding[0].display"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 18
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-histologie-icdo3|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://terminology.hl7.org/CodeSystem/icd-o-3#8500/3 ('Infiltrating duct carcinoma, NOS')'' in ValueSet."
            },
            "expression": [
              "Observation/mii-exa-onko-histologie-icdo3: Observation.value.ofType(CodeableConcept).coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 18
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Terminology_TX_NoValid_1_CC"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-histologie-icdo3|2027.0.0-ballot.1"
              }
            ],
            "severity": "error",
            "code": "code-invalid",
            "details": {
              "text": "None of the codings provided are in the value set 'MII VS Onkologie ICD-O-3 Morphologie' (https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-icdo3-morphologie|2027.0.0-ballot.1), and a coding from this value set is required) (codes = http://terminology.hl7.org/CodeSystem/icd-o-3#8500/3)"
            },
            "expression": [
              "Observation/mii-exa-onko-histologie-icdo3: Observation.value.ofType(CodeableConcept)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 36
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-histologie-icdo3|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "informational",
            "details": {
              "text": "Got multiple matches for ''http://terminology.hl7.org/CodeSystem/icd-o-3#C50.4 ('Oberer äußerer Quadrant der Brust')'' in ValueSet."
            },
            "expression": [
              "Observation/mii-exa-onko-histologie-icdo3: Observation.bodySite.coding[0].code"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 36
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-histologie-icdo3|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "code-invalid",
            "details": {
              "text": "Got multiple matches for ''http://terminology.hl7.org/CodeSystem/icd-o-3#C50.4 ('Oberer äußerer Quadrant der Brust')'' in ValueSet."
            },
            "expression": [
              "Observation/mii-exa-onko-histologie-icdo3: Observation.bodySite.coding[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-histologie-icdo3: Observation"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_an_effectiveDateTime_or_an_effectivePeriod"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have an effective[x] ()"
            },
            "expression": [
              "Observation/mii-exa-onko-histologie-icdo3: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-kim-klass1-cM1",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-kim-klass1-cM1",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-m-kategorie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Observation/mii-exa-onko-kim-klass1-cM1: Observation.value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-m-kategorie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Observation/mii-exa-onko-kim-klass1-cM1: Observation.value.ofType(CodeableConcept).coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-kim-klass1-cM1: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-kim-klass1-cN1",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-kim-klass1-cN1",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-n-kategorie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Observation/mii-exa-onko-kim-klass1-cN1: Observation.value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-n-kategorie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Observation/mii-exa-onko-kim-klass1-cN1: Observation.value.ofType(CodeableConcept).coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-kim-klass1-cN1: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-kim-klass1-cT3c",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-kim-klass1-cT3c",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-t-kategorie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Observation/mii-exa-onko-kim-klass1-cT3c: Observation.value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-t-kategorie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Observation/mii-exa-onko-kim-klass1-cT3c: Observation.value.ofType(CodeableConcept).coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-kim-klass1-cT3c: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-kim-klass1",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-kim-klass1",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-kim-klass1: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-kim-klass2-ycM1b",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-kim-klass2-ycM1b",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 23
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-m-kategorie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Observation/mii-exa-onko-kim-klass2-ycM1b: Observation.value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 23
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-m-kategorie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Observation/mii-exa-onko-kim-klass2-ycM1b: Observation.value.ofType(CodeableConcept).coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
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            ],
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            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
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            "expression": [
              "Observation/mii-exa-onko-kim-klass2-ycM1b: Observation"
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                "valueInteger": 4
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
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            "severity": "warning",
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            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
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                "valueInteger": 1
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
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              {
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
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              {
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              {
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            "code": "invalid",
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
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            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-bundle-m-kategorie-cM0: Observation.value.ofType(CodeableConcept).coding[0].system"
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            "extension": [
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
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            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
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                "valueInteger": 1
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
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            ],
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            "code": "invalid",
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            },
            "expression": [
              "Observation/mii-exa-onko-tnm-bundle-m-kategorie-cM0: Observation"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
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              {
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        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-l-kategorie-L1: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-tnm-m-kategorie-M0",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-tnm-m-kategorie-M0",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-m-kategorie-M0: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-tnm-m-kategorie-cM0",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-tnm-m-kategorie-cM0",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-m-kategorie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-m-kategorie-cM0: Observation.value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-m-kategorie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-m-kategorie-cM0: Observation.value.ofType(CodeableConcept).coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-m-kategorie-cM0: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-tnm-m-kategorie-cM1",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-tnm-m-kategorie-cM1",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-m-kategorie-cM1: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-tnm-m-kategorie-rcM1",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-tnm-m-kategorie-rcM1",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 23
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-m-kategorie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-m-kategorie-rcM1: Observation.value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 23
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-m-kategorie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-m-kategorie-rcM1: Observation.value.ofType(CodeableConcept).coding[1].system"
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          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-m-kategorie-rcM1: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-tnm-n-kategorie-N0",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-tnm-n-kategorie-N0",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-n-kategorie-N0: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-tnm-n-kategorie-cN1",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-tnm-n-kategorie-cN1",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-n-kategorie|2027.0.0-ballot.1"
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            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-n-kategorie-cN1: Observation.value.ofType(CodeableConcept).coding[0].system"
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          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-n-kategorie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-n-kategorie-cN1: Observation.value.ofType(CodeableConcept).coding[1].system"
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          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-n-kategorie-cN1: Observation"
            ]
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    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-tnm-n-kategorie-pN0i-sn",
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        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-tnm-n-kategorie-pN0i-sn",
        "issue": [
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            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
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            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-n-kategorie-pN0i-sn: Observation"
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    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-tnm-n-kategorie-rcN1",
      "resource": {
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        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 23
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-n-kategorie|2027.0.0-ballot.1"
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            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
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            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 23
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-n-kategorie|2027.0.0-ballot.1"
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            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
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          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
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            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-n-kategorie-rcN1: Observation"
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        ]
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    },
    {
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
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            "expression": [
              "Observation/mii-exa-onko-tnm-n-kategorie-ycN0: Observation.value.ofType(CodeableConcept).coding[0].system"
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            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
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              {
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              {
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            ],
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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            "expression": [
              "Observation/mii-exa-onko-tnm-n-kategorie-ypN0: Observation.value.ofType(CodeableConcept).coding[0].system"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              {
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            ],
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
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            ],
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            "code": "invalid",
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      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-tnm-post-chemo-ycT2ycN0cM0",
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            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
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            "expression": [
              "Observation/mii-exa-onko-tnm-post-chemo-ycT2ycN0cM0: Observation"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
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            "code": "invalid",
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            "expression": [
              "Observation/mii-exa-onko-tnm-post-surgery-ypT0ypN0cM0: Observation"
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            ],
            "severity": "warning",
            "code": "invalid",
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              "text": "Best Practice Recommendation: In general, all observations should have a performer"
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            "expression": [
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
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            ],
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            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
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            "expression": [
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
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            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
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            "expression": [
              "Observation/mii-exa-onko-tnm-synth-klassifikation: Observation"
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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            "code": "not-found",
            "details": {
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            "expression": [
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
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              {
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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            "code": "invalid",
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            "expression": [
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              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-n-kategorie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-synth-meldung1-n-cN2: Observation.value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-n-kategorie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-synth-meldung1-n-cN2: Observation.value.ofType(CodeableConcept).coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-synth-meldung1-n-cN2: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-tnm-synth-meldung1-t-cT3",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-tnm-synth-meldung1-t-cT3",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-t-kategorie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-synth-meldung1-t-cT3: Observation.value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-t-kategorie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-synth-meldung1-t-cT3: Observation.value.ofType(CodeableConcept).coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-synth-meldung1-t-cT3: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-tnm-synth-meldung2-klassifikation",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-tnm-synth-meldung2-klassifikation",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-synth-meldung2-klassifikation: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-tnm-synth-meldung2-n-pN1",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-tnm-synth-meldung2-n-pN1",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-n-kategorie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-synth-meldung2-n-pN1: Observation.value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-n-kategorie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-synth-meldung2-n-pN1: Observation.value.ofType(CodeableConcept).coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-synth-meldung2-n-pN1: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-tnm-synth-meldung2-t-pT2",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-tnm-synth-meldung2-t-pT2",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-t-kategorie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-synth-meldung2-t-pT2: Observation.value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-t-kategorie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-synth-meldung2-t-pT2: Observation.value.ofType(CodeableConcept).coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-synth-meldung2-t-pT2: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-tnm-t-kategorie-Tis",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-tnm-t-kategorie-Tis",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-t-kategorie-Tis: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-tnm-t-kategorie-cT3",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-tnm-t-kategorie-cT3",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-t-kategorie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-t-kategorie-cT3: Observation.value.ofType(CodeableConcept).coding[0].system"
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          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-t-kategorie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-t-kategorie-cT3: Observation.value.ofType(CodeableConcept).coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-t-kategorie-cT3: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-tnm-t-kategorie-cT4",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-tnm-t-kategorie-cT4",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-t-kategorie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-t-kategorie-cT4: Observation.value.ofType(CodeableConcept).coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 9
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-t-kategorie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-t-kategorie-cT4: Observation.value.ofType(CodeableConcept).coding[1].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-t-kategorie-cT4: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-tnm-t-kategorie-rcT2",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-tnm-t-kategorie-rcT2",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 23
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-t-kategorie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-t-kategorie-rcT2: Observation.value.ofType(CodeableConcept).coding[0].system"
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          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 23
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-t-kategorie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-t-kategorie-rcT2: Observation.value.ofType(CodeableConcept).coding[1].system"
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          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-t-kategorie-rcT2: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-tnm-t-kategorie-uT2a2",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-tnm-t-kategorie-uT2a2",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-t-kategorie-uT2a2: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-tnm-t-kategorie-ycT2",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-tnm-t-kategorie-ycT2",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 23
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-t-kategorie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-t-kategorie-ycT2: Observation.value.ofType(CodeableConcept).coding[0].system"
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          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 23
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-t-kategorie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
            },
            "expression": [
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          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-t-kategorie-ycT2: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-tnm-t-kategorie-ypT0",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Observation-mii-exa-onko-tnm-t-kategorie-ypT0",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 23
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-t-kategorie|2027.0.0-ballot.1"
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            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.uicc.org/resources/tnm' version 'null' could not be found, so the code cannot be validated. Valid versions: [2025.1.0]"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-t-kategorie-ypT0: Observation.value.ofType(CodeableConcept).coding[0].system"
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          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 23
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-t-kategorie|2027.0.0-ballot.1"
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            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'http://snomed.info/sct' version 'null' could not be found, so the code cannot be validated. Valid versions: [http://snomed.info/sct/900000000000207008/version/20230731, http://snomed.info/sct/900000000000207008/version/20240101, http://snomed.info/sct/900000000000207008/version/20240701, http://snomed.info/sct/11000274103/version/20241115, http://snomed.info/sct/900000000000207008/version/20250101, http://snomed.info/sct/900000000000207008/version/20250701, http://snomed.info/sct/11000274103/version/20231115, http://snomed.info/sct/11010000107/version/20250921, http://snomed.info/sct/11000274103/version/20250515, http://snomed.info/sct/11000274103/version/20240515, http://snomed.info/sct/11000274103/version/20251115, http://snomed.info/sct/900000000000207008/version/20260101, http://snomed.info/sct/900000000000207008/version/20260701, http://snomed.info/sct/11000274103/version/20260515]"
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            "expression": [
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
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            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
              "Observation/mii-exa-onko-tnm-t-kategorie-ypT0: Observation"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-tnm-v-kategorie-V1",
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          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
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            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
            },
            "expression": [
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    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Observation-mii-exa-onko-tod-j",
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        "resourceType": "OperationOutcome",
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          {
            "extension": [
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "All_observations_should_have_a_performer"
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            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "Best Practice Recommendation: In general, all observations should have a performer"
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            "expression": [
              "Observation/mii-exa-onko-tod-j: Observation"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 2
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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            "code": "invalid",
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              "text": "Best Practice Recommendation: In general, all observations should have a performer"
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            "expression": [
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            "expression": [
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            "code": "invalid",
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            "expression": [
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              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/sid/patienten'"
            },
            "expression": [
              "Patient/mii-exa-onko-molecular-board-patient: Patient.identifier[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Patient-mii-exa-onko-prostata-bundle-patient",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Patient-mii-exa-onko-prostata-bundle-patient"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Patient-mii-exa-onko-tnm-bundle-legacy-patient",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Patient-mii-exa-onko-tnm-bundle-legacy-patient"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Patient-mii-exa-onko-tnm-bundle-patient",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Patient-mii-exa-onko-tnm-bundle-patient"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Patient-mii-exa-onko-tnm-synth-patient",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Patient-mii-exa-onko-tnm-synth-patient"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Procedure-PatientKimMusterperson-Procedure-1",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-PatientKimMusterperson-Procedure-1"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Procedure-PatientKimMusterperson-Procedure-2",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-PatientKimMusterperson-Procedure-2"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Procedure-PatientKimMusterperson-Procedure-3",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-PatientKimMusterperson-Procedure-3"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Procedure-PatientKimMusterperson-Procedure-4",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-PatientKimMusterperson-Procedure-4"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Procedure-PatientKimMusterperson-Procedure-4a",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-PatientKimMusterperson-Procedure-4a"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Procedure-PatientKimMusterperson-Procedure-4b",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-PatientKimMusterperson-Procedure-4b"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Procedure-PatientKimMusterperson-Procedure-4c",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-PatientKimMusterperson-Procedure-4c"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Procedure-PatientKimMusterperson-Procedure-4d",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-PatientKimMusterperson-Procedure-4d"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Procedure-PatientKimMusterperson-SystemicTherapy-1",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-PatientKimMusterperson-SystemicTherapy-1",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 38
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 23
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://fhir.de/StructureDefinition/CodingOPS#ops-regex"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: ops-regex: 'In code sind nur gültige OPS-Codes ohne Zusätze erlaubt (matches('^[1|3|5|6|8|9]-[a-zA-Z0-9]{3}([.][a-zA-Z0-9]{1,2})?[%content%]#39;))' (defined in http://fhir.de/StructureDefinition/CodingOPS)"
            },
            "expression": [
              "Procedure/PatientKimMusterperson-SystemicTherapy-1: Procedure.code.coding[0].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Procedure-PatientKimMusterperson-SystemicTherapy-2",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-PatientKimMusterperson-SystemicTherapy-2",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 38
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 23
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://fhir.de/StructureDefinition/CodingOPS#ops-regex"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: ops-regex: 'In code sind nur gültige OPS-Codes ohne Zusätze erlaubt (matches('^[1|3|5|6|8|9]-[a-zA-Z0-9]{3}([.][a-zA-Z0-9]{1,2})?[%content%]#39;))' (defined in http://fhir.de/StructureDefinition/CodingOPS)"
            },
            "expression": [
              "Procedure/PatientKimMusterperson-SystemicTherapy-2: Procedure.code.coding[0].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Procedure-PatientKimMusterperson-SystemicTherapy-3",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-PatientKimMusterperson-SystemicTherapy-3",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 38
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 23
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://fhir.de/StructureDefinition/CodingOPS#ops-regex"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: ops-regex: 'In code sind nur gültige OPS-Codes ohne Zusätze erlaubt (matches('^[1|3|5|6|8|9]-[a-zA-Z0-9]{3}([.][a-zA-Z0-9]{1,2})?[%content%]#39;))' (defined in http://fhir.de/StructureDefinition/CodingOPS)"
            },
            "expression": [
              "Procedure/PatientKimMusterperson-SystemicTherapy-3: Procedure.code.coding[0].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Procedure-mii-exa-onko-folfox-phase1",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-mii-exa-onko-folfox-phase1",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 35
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-systemische-therapie-art' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Procedure/mii-exa-onko-folfox-phase1: Procedure.code.coding[1].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Procedure-mii-exa-onko-folfox-procedure",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-mii-exa-onko-folfox-procedure",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 35
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-systemische-therapie-art' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Procedure/mii-exa-onko-folfox-procedure: Procedure.code.coding[1].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Procedure-mii-exa-onko-krk-operation",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-mii-exa-onko-krk-operation"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Procedure-mii-exa-onko-krk-stoma-markierung",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-mii-exa-onko-krk-stoma-markierung"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Procedure-mii-exa-onko-lv5fu2-phase2",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-mii-exa-onko-lv5fu2-phase2",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 35
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-systemische-therapie-art' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Procedure/mii-exa-onko-lv5fu2-phase2: Procedure.code.coding[1].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Procedure-mii-exa-onko-mamma-praeoperative-markierung-1",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-mii-exa-onko-mamma-praeoperative-markierung-1",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "INACTIVE_CONCEPT_FOUND"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-mamma-praeoperative-markierung|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The concept '103693007' has a status of inactive and its use should be reviewed"
            },
            "expression": [
              "Procedure/mii-exa-onko-mamma-praeoperative-markierung-1: Procedure.category.coding[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Procedure-mii-exa-onko-melanom-exzision-oberarm",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-mii-exa-onko-melanom-exzision-oberarm"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Procedure-mii-exa-onko-melanom-exzision-ruecken",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-mii-exa-onko-melanom-exzision-ruecken"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Procedure-mii-exa-onko-operation-1",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-mii-exa-onko-operation-1"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Procedure-mii-exa-onko-palbociclib-therapie",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-mii-exa-onko-palbociclib-therapie",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 22
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-systemische-therapie-art' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Procedure/mii-exa-onko-palbociclib-therapie: Procedure.code.coding[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 26
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 23
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://fhir.de/StructureDefinition/CodingOPS#ops-regex"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: ops-regex: 'In code sind nur gültige OPS-Codes ohne Zusätze erlaubt (matches('^[1|3|5|6|8|9]-[a-zA-Z0-9]{3}([.][a-zA-Z0-9]{1,2})?[%content%]#39;))' (defined in http://fhir.de/StructureDefinition/CodingOPS)"
            },
            "expression": [
              "Procedure/mii-exa-onko-palbociclib-therapie: Procedure.code.coding[0].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Procedure-mii-exa-onko-pertuzumab-therapie",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-mii-exa-onko-pertuzumab-therapie",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 22
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-systemische-therapie-art' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Procedure/mii-exa-onko-pertuzumab-therapie: Procedure.code.coding[1]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Procedure-mii-exa-onko-prostata-operation-prostatektomie",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-mii-exa-onko-prostata-operation-prostatektomie"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Procedure-mii-exa-onko-prostata-operation-turp",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-mii-exa-onko-prostata-operation-turp"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Procedure-mii-exa-onko-prostata-surgery-1",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-mii-exa-onko-prostata-surgery-1"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Procedure-mii-exa-onko-prostata-surgery-2",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-mii-exa-onko-prostata-surgery-2"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Procedure-mii-exa-onko-right-hemicolectomy",
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        "resourceType": "OperationOutcome",
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      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-mii-exa-onko-strahlentherapie-bestrahlung-nuklearmedizin-1"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Procedure-mii-exa-onko-strahlentherapie-bestrahlung-pci-sclc",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-mii-exa-onko-strahlentherapie-bestrahlung-pci-sclc",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 68
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 23
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://fhir.de/StructureDefinition/CodingOPS#ops-regex"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-strahlentherapie-bestrahlung-strahlentherapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: ops-regex: 'In code sind nur gültige OPS-Codes ohne Zusätze erlaubt (matches('^[1|3|5|6|8|9]-[a-zA-Z0-9]{3}([.][a-zA-Z0-9]{1,2})?[%content%]#39;))' (defined in http://fhir.de/StructureDefinition/CodingOPS)"
            },
            "expression": [
              "Procedure/mii-exa-onko-strahlentherapie-bestrahlung-pci-sclc: Procedure.code.coding[0].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Procedure-mii-exa-onko-strahlentherapie-bestrahlung-strahlentherapie-1",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-mii-exa-onko-strahlentherapie-bestrahlung-strahlentherapie-1",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 86
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 23
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://fhir.de/StructureDefinition/CodingOPS#ops-regex"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-strahlentherapie-bestrahlung-strahlentherapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: ops-regex: 'In code sind nur gültige OPS-Codes ohne Zusätze erlaubt (matches('^[1|3|5|6|8|9]-[a-zA-Z0-9]{3}([.][a-zA-Z0-9]{1,2})?[%content%]#39;))' (defined in http://fhir.de/StructureDefinition/CodingOPS)"
            },
            "expression": [
              "Procedure/mii-exa-onko-strahlentherapie-bestrahlung-strahlentherapie-1: Procedure.code.coding[0].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Procedure-mii-exa-onko-strahlentherapie-nuklearmedizin-1",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-mii-exa-onko-strahlentherapie-nuklearmedizin-1",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 49
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 23
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://fhir.de/StructureDefinition/CodingOPS#ops-regex"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-strahlentherapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: ops-regex: 'In code sind nur gültige OPS-Codes ohne Zusätze erlaubt (matches('^[1|3|5|6|8|9]-[a-zA-Z0-9]{3}([.][a-zA-Z0-9]{1,2})?[%content%]#39;))' (defined in http://fhir.de/StructureDefinition/CodingOPS)"
            },
            "expression": [
              "Procedure/mii-exa-onko-strahlentherapie-nuklearmedizin-1: Procedure.code.coding[0].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Procedure-mii-exa-onko-strahlentherapie-pci-sclc",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-mii-exa-onko-strahlentherapie-pci-sclc",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 49
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 23
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://fhir.de/StructureDefinition/CodingOPS#ops-regex"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-strahlentherapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: ops-regex: 'In code sind nur gültige OPS-Codes ohne Zusätze erlaubt (matches('^[1|3|5|6|8|9]-[a-zA-Z0-9]{3}([.][a-zA-Z0-9]{1,2})?[%content%]#39;))' (defined in http://fhir.de/StructureDefinition/CodingOPS)"
            },
            "expression": [
              "Procedure/mii-exa-onko-strahlentherapie-pci-sclc: Procedure.code.coding[0].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Procedure-mii-exa-onko-strahlentherapie-strahlentherapie-1",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-mii-exa-onko-strahlentherapie-strahlentherapie-1",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 49
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 23
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://fhir.de/StructureDefinition/CodingOPS#ops-regex"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-strahlentherapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: ops-regex: 'In code sind nur gültige OPS-Codes ohne Zusätze erlaubt (matches('^[1|3|5|6|8|9]-[a-zA-Z0-9]{3}([.][a-zA-Z0-9]{1,2})?[%content%]#39;))' (defined in http://fhir.de/StructureDefinition/CodingOPS)"
            },
            "expression": [
              "Procedure/mii-exa-onko-strahlentherapie-strahlentherapie-1: Procedure.code.coding[0].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Procedure-mii-exa-onko-systemische-therapie-1",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-mii-exa-onko-systemische-therapie-1",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 53
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 23
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://fhir.de/StructureDefinition/CodingOPS#ops-regex"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: ops-regex: 'In code sind nur gültige OPS-Codes ohne Zusätze erlaubt (matches('^[1|3|5|6|8|9]-[a-zA-Z0-9]{3}([.][a-zA-Z0-9]{1,2})?[%content%]#39;))' (defined in http://fhir.de/StructureDefinition/CodingOPS)"
            },
            "expression": [
              "Procedure/mii-exa-onko-systemische-therapie-1: Procedure.code.coding[1].code"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Procedure-mii-exa-onko-trastuzumab-therapie",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Procedure-mii-exa-onko-trastuzumab-therapie",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 22
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 4
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie|2027.0.0-ballot.1"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-systemische-therapie-art' could not be found, so the code cannot be validated"
            },
            "expression": [
              "Procedure/mii-exa-onko-trastuzumab-therapie: Procedure.code.coding[1]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Provenance-mii-exa-onko-kim-synthesis-provenance",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Provenance-mii-exa-onko-kim-synthesis-provenance"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/RequestGroup-mii-exa-onko-folfox-requestgroup-modification",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "RequestGroup-mii-exa-onko-folfox-requestgroup-modification"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/RequestGroup-mii-exa-onko-folfox-requestgroup",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "RequestGroup-mii-exa-onko-folfox-requestgroup"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/RequestGroup-mii-exa-onko-molecular-cdk46-protocol",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "RequestGroup-mii-exa-onko-molecular-cdk46-protocol"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/RequestGroup-mii-exa-onko-molecular-her2-alternatives",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "RequestGroup-mii-exa-onko-molecular-her2-alternatives"
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ResearchStudy-mii-exa-onko-studie-prob",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ResearchStudy-mii-exa-onko-studie-prob",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 6
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 34
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ResearchStudy|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://drks.de'"
            },
            "expression": [
              "ResearchStudy/mii-exa-onko-studie-prob: ResearchStudy.identifier[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 10
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/ResearchStudy|4.0.1"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://innovationsfonds.g-ba.de'"
            },
            "expression": [
              "ResearchStudy/mii-exa-onko-studie-prob: ResearchStudy.identifier[1].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/SearchParameter-mii-sp-onko-condition-ext-morphology-behavior-icdo3",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "SearchParameter-mii-sp-onko-condition-ext-morphology-behavior-icdo3",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 452
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablesearchparameter|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "SearchParameter/mii-sp-onko-condition-ext-morphology-behavior-icdo3: SearchParameter.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7842
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablesearchparameter|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "SearchParameter/mii-sp-onko-condition-ext-morphology-behavior-icdo3: SearchParameter.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8101
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/SearchParameter#spd-0"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablesearchparameter|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: spd-0: 'Name should be usable as an identifier for the module by machine processing applications such as code generation (name.matches('[A-Z]([A-Za-z0-9_]){0,254}'))' (defined in http://hl7.org/fhir/StructureDefinition/SearchParameter)"
            },
            "expression": [
              "SearchParameter/mii-sp-onko-condition-ext-morphology-behavior-icdo3: SearchParameter"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/SearchParameter-mii-sp-onko-ext-strahlentherapie-stellungzurop",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "SearchParameter-mii-sp-onko-ext-strahlentherapie-stellungzurop",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 447
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablesearchparameter|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "SearchParameter/mii-sp-onko-ext-strahlentherapie-stellungzurop: SearchParameter.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7028
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablesearchparameter|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "SearchParameter/mii-sp-onko-ext-strahlentherapie-stellungzurop: SearchParameter.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/SearchParameter-mii-sp-onko-ext-systemischetherapie-stellungzurop",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "SearchParameter-mii-sp-onko-ext-systemischetherapie-stellungzurop",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 450
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablesearchparameter|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "SearchParameter/mii-sp-onko-ext-systemischetherapie-stellungzurop: SearchParameter.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7078
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablesearchparameter|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "SearchParameter/mii-sp-onko-ext-systemischetherapie-stellungzurop: SearchParameter.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/SearchParameter-mii-sp-onko-observation-ext-tnm-n-itc",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "SearchParameter-mii-sp-onko-observation-ext-tnm-n-itc",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 438
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablesearchparameter|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "SearchParameter/mii-sp-onko-observation-ext-tnm-n-itc: SearchParameter.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7533
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablesearchparameter|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "SearchParameter/mii-sp-onko-observation-ext-tnm-n-itc: SearchParameter.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/SearchParameter-mii-sp-onko-observation-ext-tnm-n-sn-suffix",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "SearchParameter-mii-sp-onko-observation-ext-tnm-n-sn-suffix",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 444
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablesearchparameter|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "SearchParameter/mii-sp-onko-observation-ext-tnm-n-sn-suffix: SearchParameter.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7651
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablesearchparameter|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "SearchParameter/mii-sp-onko-observation-ext-tnm-n-sn-suffix: SearchParameter.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/SearchParameter-mii-sp-onko-observation-tnm-cp-praefix",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "SearchParameter-mii-sp-onko-observation-tnm-cp-praefix",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 439
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablesearchparameter|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "SearchParameter/mii-sp-onko-observation-tnm-cp-praefix: SearchParameter.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8180
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablesearchparameter|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "SearchParameter/mii-sp-onko-observation-tnm-cp-praefix: SearchParameter.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/SearchParameter-mii-sp-onko-observation-tnm-r-praefix",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "SearchParameter-mii-sp-onko-observation-tnm-r-praefix",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablesearchparameter|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "SearchParameter/mii-sp-onko-observation-tnm-r-praefix: SearchParameter.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8190
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablesearchparameter|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "SearchParameter/mii-sp-onko-observation-tnm-r-praefix: SearchParameter.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/SearchParameter-mii-sp-onko-observation-tnm-y-praefix",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "SearchParameter-mii-sp-onko-observation-tnm-y-praefix",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
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              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablesearchparameter|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "SearchParameter/mii-sp-onko-observation-tnm-y-praefix: SearchParameter.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8247
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablesearchparameter|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "SearchParameter/mii-sp-onko-observation-tnm-y-praefix: SearchParameter.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/SearchParameter-mii-sp-onko-procedure-ext-operation-intention",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "SearchParameter-mii-sp-onko-procedure-ext-operation-intention",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 446
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablesearchparameter|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "SearchParameter/mii-sp-onko-procedure-ext-operation-intention: SearchParameter.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7669
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablesearchparameter|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "SearchParameter/mii-sp-onko-procedure-ext-operation-intention: SearchParameter.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/SearchParameter-mii-sp-onko-procedure-ext-strahlentherapie-bs-boost",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "SearchParameter-mii-sp-onko-procedure-ext-strahlentherapie-bs-boost",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 452
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablesearchparameter|2.0.0"
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            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "SearchParameter/mii-sp-onko-procedure-ext-strahlentherapie-bs-boost: SearchParameter.meta.extension[1].extension[2].value.ofType(uri)"
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          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7788
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablesearchparameter|2.0.0"
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            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "SearchParameter/mii-sp-onko-procedure-ext-strahlentherapie-bs-boost: SearchParameter.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/SearchParameter-mii-sp-onko-procedure-ext-strahlentherapie-bs-einzeldosis",
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        "resourceType": "OperationOutcome",
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          {
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablesearchparameter|2.0.0"
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            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "SearchParameter/mii-sp-onko-procedure-ext-strahlentherapie-bs-einzeldosis: SearchParameter.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7908
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
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              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "SearchParameter/mii-sp-onko-procedure-ext-strahlentherapie-bs-einzeldosis: SearchParameter.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
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        "resourceType": "OperationOutcome",
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          {
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              {
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
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            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "SearchParameter/mii-sp-onko-procedure-ext-strahlentherapie-bs-gesamtdosis: SearchParameter.meta.extension[1].extension[2].value.ofType(uri)"
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          },
          {
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
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            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "SearchParameter/mii-sp-onko-procedure-ext-strahlentherapie-bs-gesamtdosis: SearchParameter.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
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              {
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              {
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              {
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            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "SearchParameter/mii-sp-onko-procedure-ext-strahlentherapie-intention: SearchParameter.meta.extension[1].extension[2].value.ofType(uri)"
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              {
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              {
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            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "SearchParameter/mii-sp-onko-procedure-ext-strahlentherapie-intention: SearchParameter.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/SearchParameter-mii-sp-onko-procedure-ext-systemischetherapie-intention",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
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            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "SearchParameter/mii-sp-onko-procedure-ext-systemischetherapie-intention: SearchParameter.meta.extension[1].extension[2].value.ofType(uri)"
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          },
          {
            "extension": [
              {
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
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            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "SearchParameter/mii-sp-onko-procedure-ext-systemischetherapie-intention: SearchParameter.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/SearchParameter-mii-sp-onko-procedure-strahlentherapie-applikationsart",
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              {
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
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            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
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          },
          {
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              {
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
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            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "SearchParameter/mii-sp-onko-procedure-strahlentherapie-applikationsart: SearchParameter.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/SearchParameter-mii-sp-onko-procedure-strahlentherapie-lateralitaet",
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              {
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
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            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
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          },
          {
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              {
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              {
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              {
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            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
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            },
            "expression": [
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          }
        ]
      }
    },
    {
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            "expression": [
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          {
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            "details": {
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          }
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    {
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    {
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        "resourceType": "OperationOutcome",
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    {
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    {
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    {
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              {
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            "details": {
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            "expression": [
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    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-ex-onko-operation-intention",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-ex-onko-operation-intention",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 436
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-ex-onko-operation-intention: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45364
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-ex-onko-operation-intention: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-ex-onko-operation-urgency",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-ex-onko-operation-urgency",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 434
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-ex-onko-operation-urgency: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45422
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-ex-onko-operation-urgency: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "Publisher"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The Implementation Guide contains no examples for this extension"
            },
            "expression": [
              "StructureDefinition.where(url = 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-ex-onko-operation-urgency')"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-ex-onko-strahlentherapie-bestrahlung-boost",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-ex-onko-strahlentherapie-bestrahlung-boost",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 451
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-ex-onko-strahlentherapie-bestrahlung-boost: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 30589
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-ex-onko-strahlentherapie-bestrahlung-boost: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-ex-onko-strahlentherapie-bestrahlung-einzeldosis",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-ex-onko-strahlentherapie-bestrahlung-einzeldosis",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 457
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-ex-onko-strahlentherapie-bestrahlung-einzeldosis: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 34954
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-ex-onko-strahlentherapie-bestrahlung-einzeldosis: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-ex-onko-strahlentherapie-bestrahlung-gesamtdosis",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-ex-onko-strahlentherapie-bestrahlung-gesamtdosis",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 457
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-ex-onko-strahlentherapie-bestrahlung-gesamtdosis: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 34894
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-ex-onko-strahlentherapie-bestrahlung-gesamtdosis: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-ex-onko-strahlentherapie-bestrahlung-seitenlokalisation",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-ex-onko-strahlentherapie-bestrahlung-seitenlokalisation",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 464
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-ex-onko-strahlentherapie-bestrahlung-seitenlokalisation: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 31050
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-ex-onko-strahlentherapie-bestrahlung-seitenlokalisation: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-ex-onko-strahlentherapie-intention",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-ex-onko-strahlentherapie-intention",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 443
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-ex-onko-strahlentherapie-intention: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45568
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-ex-onko-strahlentherapie-intention: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-ex-onko-strahlentherapie-stellungzurop",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-ex-onko-strahlentherapie-stellungzurop",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 447
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-ex-onko-strahlentherapie-stellungzurop: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45910
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-ex-onko-strahlentherapie-stellungzurop: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-ex-onko-systemische-therapie-intention",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-ex-onko-systemische-therapie-intention",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 447
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-ex-onko-systemische-therapie-intention: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45724
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-ex-onko-systemische-therapie-intention: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-ex-onko-systemische-therapie-stellungzurop",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-ex-onko-systemische-therapie-stellungzurop",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 451
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-ex-onko-systemische-therapie-stellungzurop: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46052
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-ex-onko-systemische-therapie-stellungzurop: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-ex-onko-tnm-a-praefix",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-ex-onko-tnm-a-praefix",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 430
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-ex-onko-tnm-a-praefix: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42391
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-ex-onko-tnm-a-praefix: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "Publisher"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The Implementation Guide contains no examples for this extension"
            },
            "expression": [
              "StructureDefinition.where(url = 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-ex-onko-tnm-a-praefix')"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-ex-onko-tnm-cp-praefix",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-ex-onko-tnm-cp-praefix",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 431
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-ex-onko-tnm-cp-praefix: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42569
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-ex-onko-tnm-cp-praefix: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-ex-onko-tnm-itc-suffix",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-ex-onko-tnm-itc-suffix",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 431
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-ex-onko-tnm-itc-suffix: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41873
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-ex-onko-tnm-itc-suffix: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-ex-onko-tnm-r-praefix",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-ex-onko-tnm-r-praefix",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 430
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-ex-onko-tnm-r-praefix: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42430
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-ex-onko-tnm-r-praefix: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-ex-onko-tnm-sn-suffix",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-ex-onko-tnm-sn-suffix",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 430
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-ex-onko-tnm-sn-suffix: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41893
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-ex-onko-tnm-sn-suffix: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-ex-onko-tnm-y-praefix",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-ex-onko-tnm-y-praefix",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 430
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-ex-onko-tnm-y-praefix: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42505
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-ex-onko-tnm-y-praefix: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-ex-onko-transformation-von",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-ex-onko-transformation-von",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 435
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-ex-onko-transformation-von: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 30381
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-ex-onko-transformation-von: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-lm-mvgenomseq-onkologie",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-lm-mvgenomseq-onkologie",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 432
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 521160
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 522302
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 522923
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 524688
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 525235
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 525884
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 527677
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 530387
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 531028
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 531695
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[8]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 533506
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[9]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 536234
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[10]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 536771
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[11]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 537626
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[12]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 538231
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[13]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 538827
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[14]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 539387
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[15]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 540154
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[16]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 540352
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_String_WS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "value should not start or finish with whitespace 'Phänotypisierung nach HPO '"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[17].short"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 540812
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[17]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 541464
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[18]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 541936
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[19]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 542617
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[20]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 543181
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[21]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 543702
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[22]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 544360
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[23]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 545013
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[24]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 545683
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[25]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 546360
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[26]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 548181
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[27]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 550919
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[28]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 551411
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[29]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 551862
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[30]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 552646
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[31]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 553337
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[32]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 555172
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[33]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 557924
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[34]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 558359
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[35]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 558868
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[36]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 559349
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[37]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 559865
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[38]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 560445
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[39]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 561009
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[40]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 561727
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[41]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 562424
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[42]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 564265
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[43]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 567023
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[44]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 567604
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[45]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 568151
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[46]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 568701
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[47]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 569245
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[48]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 569780
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[49]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 570270
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[50]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 570919
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[51]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 571450
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[52]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 572026
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[53]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 572685
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[54]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 574488
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[55]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 577208
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[56]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 577903
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[57]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 578596
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[58]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 580433
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[59]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 583187
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[60]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 583583
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[61]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 583935
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[62]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 584332
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[63]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 584717
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[64]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 585124
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[65]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 585564
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[66]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 586016
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[67]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 586485
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[68]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 587202
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[69]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 587899
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[70]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 589740
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[71]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 592498
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[72]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 592900
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[73]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 593311
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[74]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 593728
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[75]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 594117
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[76]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 594487
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[77]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 594912
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[78]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 595328
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[79]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 595708
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[80]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 596166
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[81]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 596805
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[82]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 597506
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[83]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 599351
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[84]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 602113
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[85]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 602521
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[86]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 602944
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[87]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 603303
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[88]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 603695
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[89]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 604144
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[90]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 604581
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[91]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 604999
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[92]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 605463
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[93]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 606095
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[94]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 606794
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[95]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 608637
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[96]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 611397
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[97]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 611802
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[98]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 612163
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[99]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 612579
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[100]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 613062
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[101]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 613470
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[102]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 613904
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[103]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 614312
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[104]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 614730
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[105]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 615142
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[106]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 615574
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[107]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 616035
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[108]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 616578
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[109]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 617227
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[110]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 619020
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[111]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 621730
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[112]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 622359
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[113]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 623052
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[114]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 624889
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[115]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 627643
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[116]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 628003
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[117]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 628426
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[118]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 628887
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[119]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 629357
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[120]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 629785
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[121]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 630213
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[122]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 630731
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[123]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 631232
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[124]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 631689
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[125]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 632317
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[126]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 633000
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[127]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 634827
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[128]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 637571
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[129]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 637950
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[130]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 638386
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[131]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 638760
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[132]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 639129
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[133]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 639538
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[134]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 639897
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[135]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 640373
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[136]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 640800
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[137]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 641201
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[138]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 641789
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[139]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 642476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[140]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 644307
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[141]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 647055
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[142]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 647452
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[143]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 647912
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[144]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 648306
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[145]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 648693
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[146]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 649142
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[147]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 649561
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[148]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 650070
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[149]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 650707
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[150]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 651408
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[151]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 653253
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[152]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 656015
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[153]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 656435
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[154]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 656932
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[155]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 657555
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[156]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 658212
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[157]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 660013
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[158]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 662731
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[159]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 663035
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[160]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 663412
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[161]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 663782
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[162]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 664171
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[163]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 664566
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[164]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 664914
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[165]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 665234
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[166]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 665813
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[167]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 666490
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[168]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 668311
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[169]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 671049
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[170]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 671452
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[171]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 671819
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[172]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 672179
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[173]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 672601
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[174]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 673080
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[175]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 673486
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[176]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 673883
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[177]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 674389
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[178]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 675026
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[179]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 675727
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[180]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 677572
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[181]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 680334
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[182]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 680762
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[183]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 681284
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[184]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 681738
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.snapshot.element[185]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 681978
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 682189
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 682485
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 682916
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 683655
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 684154
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 684652
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 685099
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 685763
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[8]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 685961
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_String_WS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "value should not start or finish with whitespace 'Phänotypisierung nach HPO '"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[9].short"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 686314
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[9]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 686868
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[10]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 687241
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[11]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 687827
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[12]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 688290
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[13]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 688710
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[14]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 689257
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[15]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 689792
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[16]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 690112
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[17]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 690498
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[18]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 690841
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[19]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 691268
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[20]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 691600
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[21]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 691999
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[22]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 692371
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[23]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 692774
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[24]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 693241
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[25]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 693687
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[26]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 694045
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[27]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 694512
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[28]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 694939
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[29]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 695378
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[30]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 695806
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[31]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 696226
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[32]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 696604
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[33]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 697132
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[34]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 697537
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[35]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 697772
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[36]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 698109
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[37]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 698394
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[38]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 698642
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[39]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 698928
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[40]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 699203
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[41]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 699496
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[42]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 699822
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[43]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 700161
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[44]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 700509
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[45]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 700866
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[46]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 701155
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[47]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 701457
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[48]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 701761
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[49]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 702044
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[50]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 702302
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[51]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 702608
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[52]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 702907
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[53]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 703174
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[54]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 703517
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[55]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 703794
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[56]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 704087
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[57]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 704395
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[58]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 704646
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[59]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 704929
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[60]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 705262
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[61]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 705582
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[62]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 705880
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[63]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 706227
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[64]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 706498
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[65]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 706789
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[66]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 707043
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[67]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 707345
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[68]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 707705
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[69]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 708006
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[70]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 708333
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[71]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 708634
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[72]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 708945
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[73]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 709250
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[74]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 709566
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[75]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 709911
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[76]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 710118
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[77]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 710389
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[78]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 710643
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[79]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 710949
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[80]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 711291
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[81]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 711638
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[82]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 711946
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[83]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 712251
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[84]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 712632
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[85]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 713000
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[86]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 713333
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[87]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 713608
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[88]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 713881
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[89]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 714213
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[90]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 714482
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[91]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 714744
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[92]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 715047
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[93]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 715299
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[94]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 715647
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[95]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 715968
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[96]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 716265
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[97]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 716498
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[98]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 716787
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[99]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 717136
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[100]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 717424
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[101]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 717702
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[102]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 718043
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[103]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 718356
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[104]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 718744
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[105]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 719019
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[106]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 719324
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[107]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 719701
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[108]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 719984
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[109]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 720200
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[110]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 720478
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[111]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 720747
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[112]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 721049
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[113]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 721350
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[114]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 721601
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[115]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 721828
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[116]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 722057
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[117]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 722358
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[118]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 722619
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[119]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 722874
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[120]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 723186
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[121]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 723554
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[122]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 723844
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[123]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 724131
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[124]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 724515
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[125]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 724790
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[126]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 725104
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[127]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 725498
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[128]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 725826
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-mvgenomseq-onkologie: StructureDefinition.differential.element[129]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-lm-onko-organspezifische-zusatzmodule",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-lm-onko-organspezifische-zusatzmodule",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 446
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 286616
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 288043
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 288692
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 290485
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 291334
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 291995
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 293800
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 296522
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 297247
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 298154
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[8]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 298861
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[9]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 300712
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[10]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 303480
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[11]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 304113
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[12]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 304943
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[13]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 305759
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[14]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 306686
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[15]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 307399
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[16]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 309256
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[17]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 312030
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[18]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 312681
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[19]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 313523
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[20]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 314351
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[21]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 314996
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[22]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 316029
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[23]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 316738
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[24]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 318591
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[25]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 321361
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[26]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 322065
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[27]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 323054
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[28]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 323745
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[29]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 325580
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[30]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 328332
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[31]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 328984
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[32]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 329665
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[33]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 330283
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[34]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 330868
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[35]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 331835
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[36]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 332526
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[37]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 334361
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[38]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 337113
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[39]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 337950
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[40]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 338677
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[41]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 340548
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[42]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 343336
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[43]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 344134
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[44]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 344995
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[45]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 345728
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[46]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 347605
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[47]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 350399
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[48]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 351496
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[49]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 352259
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[50]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 354166
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[51]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 356990
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[52]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 357715
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[53]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 358618
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[54]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 359538
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[55]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 360249
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[56]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 362104
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[57]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 364876
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[58]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 365479
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[59]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 366213
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[60]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 367273
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[61]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 368016
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[62]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 369903
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[63]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 372707
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[64]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 373341
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[65]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 374025
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[66]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 374880
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[67]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 375617
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[68]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 377498
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[69]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 380296
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[70]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 381144
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[71]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 382011
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[72]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 382807
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[73]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 383516
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[74]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 384396
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[75]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 385143
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[76]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 387034
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[77]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 389842
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[78]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 390702
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[79]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 391604
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[80]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 392271
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[81]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 394082
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[82]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 396810
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[83]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 397724
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[84]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 398417
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[85]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 400254
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[86]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 403008
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[87]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 403557
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[88]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 404413
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[89]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 405380
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[90]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 406077
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[91]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 407918
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[92]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 410676
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[93]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 411269
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[94]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 411865
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[95]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 412530
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[96]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 413327
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[97]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 414030
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[98]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 415877
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[99]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 418641
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[100]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 419290
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[101]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 419959
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[102]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 420666
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[103]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 421453
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[104]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 422053
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[105]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 422644
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[106]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 423678
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[107]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 424399
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[108]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 426264
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[109]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 429046
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[110]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 429728
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[111]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 430554
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[112]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 431512
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[113]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 432193
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[114]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 434018
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[115]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 436760
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[116]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 437516
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[117]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 438273
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[118]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 439146
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[119]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 439835
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[120]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 441668
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[121]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 444418
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[122]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 444953
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[123]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 445555
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[124]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 446289
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[125]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 447278
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[126]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 447957
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[127]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 449780
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[128]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 452520
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[129]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 453306
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[130]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 454066
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[131]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 454768
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.snapshot.element[132]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 455212
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 455719
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 456343
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 456885
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 457404
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 458106
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 458797
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 459356
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 459890
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[8]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 460601
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[9]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 461301
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[10]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 461848
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[11]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 462515
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[12]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 463100
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[13]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 463732
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[14]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 464271
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[15]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 464830
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[16]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 465344
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[17]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 465828
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[18]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 466438
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[19]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 466900
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[20]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 467560
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[21]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 468043
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[22]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 468747
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[23]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 469318
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[24]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 470058
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[25]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 470611
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[26]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 471091
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[27]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 471698
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[28]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 472375
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[29]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 472877
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[30]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 473424
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[31]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 473899
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[32]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 474601
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[33]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 475316
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[34]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 475977
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[35]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 476552
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[36]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 477047
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[37]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 477756
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[38]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 478313
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[39]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 478869
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[40]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 479312
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[41]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 480057
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[42]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 480664
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[43]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 481144
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[44]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 481626
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[45]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 482185
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[46]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 482619
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[47]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 483150
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[48]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 483700
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[49]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 484279
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[50]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 484940
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[51]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 485445
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[52]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 485940
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[53]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 486602
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[54]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 487153
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[55]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 487848
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[56]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 488454
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[57]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 489097
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[58]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 489747
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[59]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 490264
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[60]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 490696
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[61]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 491190
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[62]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 491819
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[63]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 492457
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[64]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 493130
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[65]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 493774
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[66]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 494366
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko-organspezifische-zusatzmodule: StructureDefinition.differential.element[67]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-lm-onko",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-lm-onko",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 416
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 425178
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 580641
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/StructureDefinition#sdf-3"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "error",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: sdf-3: 'Each element definition in a snapshot must have a formal definition and cardinalities (element.all(definition.exists() and min.exists() and max.exists()))' (defined in http://hl7.org/fhir/StructureDefinition/StructureDefinition)"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 426237
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 426826
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 428559
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 429199
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 429806
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 431557
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 434225
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 434864
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 435465
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[8]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 436009
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[9]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 436594
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[10]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 437199
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[11]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 437803
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[12]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 438487
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[13]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 439124
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[14]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 439775
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[15]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 440339
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[16]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 440950
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[17]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 442705
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[18]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 445377
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[19]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 445875
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[20]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 446473
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[21]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 447081
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[22]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 447784
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[23]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 448296
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[24]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 448901
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[25]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 449551
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[26]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 450188
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[27]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 450840
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[28]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 451479
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[29]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 451991
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[30]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 452600
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[31]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 453225
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[32]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 454994
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[33]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 457680
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[34]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 458154
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[35]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 458610
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[36]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 459280
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[37]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 459873
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[38]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 460482
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[39]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 461094
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[40]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 461706
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[41]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 462318
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[42]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 462831
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[43]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 463367
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[44]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 463905
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[45]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 464442
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[46]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 465048
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[47]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 465641
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[48]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 466266
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[49]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 466843
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[50]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 467338
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[51]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 467992
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[52]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 468629
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[53]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 470410
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[54]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 473108
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[55]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 473732
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[56]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 474365
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[57]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 475031
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[58]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 475621
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[59]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 476240
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[60]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 478003
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[61]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 480683
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[62]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 481412
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[63]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 482027
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[64]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 482617
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[65]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 483236
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[66]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 484999
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[67]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 487679
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[68]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 488167
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[69]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 488693
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[70]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 489364
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[71]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 490009
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[72]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 491798
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[73]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 494504
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[74]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 495041
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[75]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 495601
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[76]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 496210
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[77]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 497963
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[78]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 500633
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[79]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 501083
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[80]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 501439
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[81]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 501932
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[82]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 502417
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[83]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 502903
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[84]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 503505
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[85]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 504128
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[86]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 505895
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[87]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 508579
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[88]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 509144
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[89]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 509752
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[90]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 510272
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[91]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 511221
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[92]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 511900
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[93]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 513723
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[94]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 516463
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[95]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 517142
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[96]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 517934
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[97]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 518512
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[98]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 519077
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[99]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 519780
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[100]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 520433
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[101]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 521128
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[102]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 521778
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[103]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 522629
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[104]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 523260
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[105]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 523883
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[106]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 524512
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[107]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 526285
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[108]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 528975
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[109]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 529537
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[110]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 530180
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[111]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 530776
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[112]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 531352
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[113]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 532052
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[114]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 532576
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[115]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 533193
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[116]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 533804
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[117]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 534441
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[118]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 535060
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[119]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 536823
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[120]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 539503
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[121]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 540081
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[122]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 540736
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[123]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 541582
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[124]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 542130
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[125]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 542735
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[126]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 544484
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[127]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 547150
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[128]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 547590
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[129]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 548066
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[130]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 548495
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[131]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 548937
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[132]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 549374
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[133]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 550051
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[134]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 550670
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[135]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 552433
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[136]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 555113
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[137]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 555675
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[138]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 556209
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[139]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 556813
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[140]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 557601
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[141]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 558438
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[142]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 559115
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[143]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 559639
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[144]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 560236
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[145]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 561977
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[146]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 564635
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[147]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 564996
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[148]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 565412
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[149]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 565859
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[150]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 566340
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[151]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 566997
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[152]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 567624
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[153]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 569395
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[154]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 572083
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[155]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 572620
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[156]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 573145
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[157]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 573787
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[158]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 574410
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[159]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 576177
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[160]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 578861
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[161]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 579401
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[162]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 579913
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[163]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 580639
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.snapshot.element[164]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 580785
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 581110
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 581659
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 582167
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 582624
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 583124
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 583637
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 584158
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 584755
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[8]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 585304
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[9]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 585872
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[10]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 586119
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[11]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 586537
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[12]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 587051
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[13]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 587584
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[14]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 588197
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[15]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 588630
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[16]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 589168
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[17]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 589730
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[18]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 590281
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[19]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 590837
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[20]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 591382
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[21]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 591828
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[22]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 592113
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[23]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 592512
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[24]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 592891
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[25]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 593484
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[26]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 594000
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[27]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 594532
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[28]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 595063
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[29]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 595594
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[30]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 596125
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[31]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 596558
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[32]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 597017
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[33]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 597475
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[34]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 597932
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[35]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 598458
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[36]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 598971
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[37]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 599515
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[38]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 600012
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[39]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 600429
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[40]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 600753
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[41]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 601278
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[42]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 601813
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[43]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 602375
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[44]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 602644
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[45]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 603288
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[46]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 603817
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[47]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 604086
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[48]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 604485
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[49]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 604932
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[50]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 605269
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[51]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 605716
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[52]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 605960
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[53]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 606340
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[54]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 606630
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[55]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 607057
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[56]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 607473
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[57]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 607886
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[58]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 608165
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[59]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 608639
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[60]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 609157
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[61]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 609586
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[62]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 610185
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[63]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 610744
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[64]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 611411
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[65]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 611873
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[66]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 612324
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[67]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 612902
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[68]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 613434
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[69]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 614008
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[70]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 614537
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[71]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 615271
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[72]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 615787
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[73]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 616084
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[74]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 616549
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[75]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 617096
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[76]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 617593
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[77]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 617994
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_String_WS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "value should not start or finish with whitespace 'MedicationStatement.medicationCodeableConcept.text '"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[78].mapping[0].map"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 618073
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[78]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 618678
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[79]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 619108
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[80]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 619633
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[81]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 620147
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[82]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 620463
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[83]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 620954
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[84]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 621523
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[85]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 622279
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[86]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 622513
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[87]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 622884
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[88]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 623274
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[89]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 623616
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[90]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 623972
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[91]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 624324
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[92]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 624680
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[93]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 625144
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[94]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 625582
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[95]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 626087
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[96]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 626770
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[97]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 627501
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[98]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 628067
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[99]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 628281
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[100]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 628578
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[101]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 628926
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[102]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 629305
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[103]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 629711
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[104]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 630043
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[105]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 630490
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[106]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 630918
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[107]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 631237
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[108]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 631689
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[109]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 632114
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[110]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 632743
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "http://hl7.org/fhir/StructureDefinition/ElementDefinition#eld-20"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invariant",
            "details": {
              "text": "Constraint failed: eld-20: 'Element names should be simple alphanumerics with a max of 64 characters, or code generation tools may be broken (path.matches('[A-Za-z][A-Za-z0-9]*(\\\\.[a-z][A-Za-z0-9]*(\\\\[x])?)*'))'"
            },
            "expression": [
              "StructureDefinition/mii-lm-onko: StructureDefinition.differential.element[111]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-allgemeiner-leistungszustand-ecog",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-allgemeiner-leistungszustand-ecog",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 450
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
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              }
            ],
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            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-allgemeiner-leistungszustand-ecog: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
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              {
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            ],
            "severity": "warning",
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            "details": {
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            "expression": [
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            ],
            "severity": "warning",
            "code": "not-found",
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          }
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          },
          {
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            "expression": [
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          {
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    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-diagnose-primaertumor",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-diagnose-primaertumor",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 438
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-diagnose-primaertumor: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 256581
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-diagnose-primaertumor: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 281225
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/condition-related'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/condition-related' to 'http://hl7.org/fhir/StructureDefinition/condition-related|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-diagnose-primaertumor: StructureDefinition.snapshot.element[16].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 286541
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/condition-assertedDate'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/condition-assertedDate' to 'http://hl7.org/fhir/StructureDefinition/condition-assertedDate|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-diagnose-primaertumor: StructureDefinition.snapshot.element[21].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 310902
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/condition-occurredFollowing'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/condition-occurredFollowing' to 'http://hl7.org/fhir/StructureDefinition/condition-occurredFollowing|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-diagnose-primaertumor: StructureDefinition.snapshot.element[42].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 315509
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/ValueSet/condition-predecessor'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '4.0.1', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/ValueSet/condition-predecessor' to 'http://hl7.org/fhir/ValueSet/condition-predecessor|4.0.1'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-diagnose-primaertumor: StructureDefinition.snapshot.element[46].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 317754
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/condition-dueTo'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/condition-dueTo' to 'http://hl7.org/fhir/StructureDefinition/condition-dueTo|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-diagnose-primaertumor: StructureDefinition.snapshot.element[48].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 322317
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/ValueSet/condition-cause'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '4.0.1', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/ValueSet/condition-cause' to 'http://hl7.org/fhir/ValueSet/condition-cause|4.0.1'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-diagnose-primaertumor: StructureDefinition.snapshot.element[52].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 502926
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/bodySite'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/bodySite' to 'http://hl7.org/fhir/StructureDefinition/bodySite|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-diagnose-primaertumor: StructureDefinition.snapshot.element[184].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 652498
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/condition-occurredFollowing'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/condition-occurredFollowing' to 'http://hl7.org/fhir/StructureDefinition/condition-occurredFollowing|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-diagnose-primaertumor: StructureDefinition.differential.element[7].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 654124
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/condition-dueTo'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/condition-dueTo' to 'http://hl7.org/fhir/StructureDefinition/condition-dueTo|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-diagnose-primaertumor: StructureDefinition.differential.element[10].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_ED_EXPERIMENTAL_BINDING"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The definition for the element 'Condition.code.coding' binds to the value set 'https://www.medizininformatik-initiative.de/fhir/core/modul-diagnose/ValueSet/diagnoses-sct' which is experimental, but this structure is not labeled as experimental"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-diagnose-primaertumor: StructureDefinition.snapshot.element[164].binding"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_ED_EXPERIMENTAL_BINDING"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The definition for the element 'Condition.code.coding' binds to the value set 'https://www.medizininformatik-initiative.de/fhir/core/modul-diagnose/ValueSet/mii-vs-diagnose-orphanet' which is experimental, but this structure is not labeled as experimental"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-diagnose-primaertumor: StructureDefinition.snapshot.element[172].binding"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "SD_ED_EXPERIMENTAL_BINDING"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The definition for the element 'Condition.bodySite.coding' binds to the value set 'https://www.medizininformatik-initiative.de/fhir/core/modul-diagnose/ValueSet/mii-vs-diagnose-bodystructure-snomed' which is experimental, but this structure is not labeled as experimental"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-diagnose-primaertumor: StructureDefinition.snapshot.element[186].binding"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-fernmetastasen",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-fernmetastasen",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 431
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-fernmetastasen: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 106281
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-fernmetastasen: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-fruehere-tumorerkrankung",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-fruehere-tumorerkrankung",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 441
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-fruehere-tumorerkrankung: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 176423
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-fruehere-tumorerkrankung: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 200636
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/condition-assertedDate'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/condition-assertedDate' to 'http://hl7.org/fhir/StructureDefinition/condition-assertedDate|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-fruehere-tumorerkrankung: StructureDefinition.snapshot.element[16].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 279091
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/condition-assertedDate'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/condition-assertedDate' to 'http://hl7.org/fhir/StructureDefinition/condition-assertedDate|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-fruehere-tumorerkrankung: StructureDefinition.differential.element[3].type[0].profile[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-genetische-variante",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-genetische-variante",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 436
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-genetische-variante: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 110309
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-genetische-variante: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 134161
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/observation-secondaryFinding'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/observation-secondaryFinding' to 'http://hl7.org/fhir/StructureDefinition/observation-secondaryFinding|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-genetische-variante: StructureDefinition.snapshot.element[16].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 135143
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/bodySite'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/bodySite' to 'http://hl7.org/fhir/StructureDefinition/bodySite|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-genetische-variante: StructureDefinition.snapshot.element[17].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 759477
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "The slice 'labCategory' on path 'Observation.category' is not marked as 'must-support' which is not consistent with the element that defines the slicing, where 'must-support' is true"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-genetische-variante: StructureDefinition.snapshot"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 759477
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "The slice 'geCategory' on path 'Observation.category' is not marked as 'must-support' which is not consistent with the element that defines the slicing, where 'must-support' is true"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-genetische-variante: StructureDefinition.snapshot"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 759477
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "The slice 'oBDS' on path 'Observation.interpretation' is not marked as 'must-support' which is not consistent with the element that defines the slicing, where 'must-support' is true"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-genetische-variante: StructureDefinition.snapshot"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-grading",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-grading",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 424
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-grading: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 117835
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-grading: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 245855
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "The slice 'snomed' on path 'Observation.code.coding' is not marked as 'must-support' which is not consistent with the element that defines the slicing, where 'must-support' is true"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-grading: StructureDefinition.snapshot"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-histologie-icdo3",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-histologie-icdo3",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 433
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-histologie-icdo3: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 122708
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-histologie-icdo3: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-krk-abstand-aboral",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-krk-abstand-aboral",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 435
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-krk-abstand-aboral: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71492
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-krk-abstand-aboral: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-krk-abstand-anokutan",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-krk-abstand-anokutan",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 437
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-krk-abstand-anokutan: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 80972
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-krk-abstand-anokutan: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-krk-abstand-circumferelle-resektionsebene",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-krk-abstand-circumferelle-resektionsebene",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 458
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-krk-abstand-circumferelle-resektionsebene: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72438
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-krk-abstand-circumferelle-resektionsebene: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-krk-anastomoseninsuffizienz",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-krk-anastomoseninsuffizienz",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 444
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-krk-anastomoseninsuffizienz: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 73242
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-krk-anastomoseninsuffizienz: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-krk-mrt-mesorektale-faszie",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-krk-mrt-mesorektale-faszie",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 443
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-krk-mrt-mesorektale-faszie: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 110457
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-krk-mrt-mesorektale-faszie: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-krk-operation",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-krk-operation",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 430
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-krk-operation: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42139
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-krk-operation: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 246311
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/bodySite'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/bodySite' to 'http://hl7.org/fhir/StructureDefinition/bodySite|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-krk-operation: StructureDefinition.snapshot.element[152].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 278252
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_String_WS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "value should not start or finish with whitespace 'OP Komplikationen '"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-krk-operation: StructureDefinition.snapshot.element[176].mapping[0].comment"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-krk-specimen",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-krk-specimen",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 429
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-krk-specimen: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40782
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-krk-specimen: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 79131
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://terminology.hl7.org/ValueSet/v2-0487'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '3.0.0', found versions: 2.0.0 (from hl7.terminology.r4#6.2.0), 3.0.0 (from hl7.terminology.r4#7.1.0). Suggested fix: change the canonical reference from 'http://terminology.hl7.org/ValueSet/v2-0487' to 'http://terminology.hl7.org/ValueSet/v2-0487|3.0.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-krk-specimen: StructureDefinition.snapshot.element[28].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 97227
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://terminology.hl7.org/ValueSet/v2-0916'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '3.0.0', found versions: 2.0.0 (from hl7.terminology.r4#6.2.0), 3.0.0 (from hl7.terminology.r4#7.1.0). Suggested fix: change the canonical reference from 'http://terminology.hl7.org/ValueSet/v2-0916' to 'http://terminology.hl7.org/ValueSet/v2-0916|3.0.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-krk-specimen: StructureDefinition.snapshot.element[44].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 116817
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://terminology.hl7.org/ValueSet/v2-0371'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '3.0.0', found versions: 2.0.0 (from hl7.terminology.r4#6.2.0), 3.0.0 (from hl7.terminology.r4#7.1.0). Suggested fix: change the canonical reference from 'http://terminology.hl7.org/ValueSet/v2-0371' to 'http://terminology.hl7.org/ValueSet/v2-0371|3.0.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-krk-specimen: StructureDefinition.snapshot.element[62].binding.valueSet"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-krk-stoma-markierung",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-krk-stoma-markierung",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 437
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-krk-stoma-markierung: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 83258
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-krk-stoma-markierung: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 248259
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/bodySite'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/bodySite' to 'http://hl7.org/fhir/StructureDefinition/bodySite|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-krk-stoma-markierung: StructureDefinition.snapshot.element[119].type[0].profile[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-liste-evidenz-erstdiagnose",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-liste-evidenz-erstdiagnose",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 443
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-liste-evidenz-erstdiagnose: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57634
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-liste-evidenz-erstdiagnose: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-mamma-her2neu-status",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-mamma-her2neu-status",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 437
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-mamma-her2neu-status: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 174668
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-mamma-her2neu-status: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-mamma-menopause-status",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-mamma-menopause-status",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 439
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-mamma-menopause-status: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69573
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-mamma-menopause-status: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-mamma-operation",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-mamma-operation",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 432
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-mamma-operation: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 89863
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-mamma-operation: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 294309
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/bodySite'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/bodySite' to 'http://hl7.org/fhir/StructureDefinition/bodySite|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-mamma-operation: StructureDefinition.snapshot.element[152].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 326250
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_String_WS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "value should not start or finish with whitespace 'OP Komplikationen '"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-mamma-operation: StructureDefinition.snapshot.element[176].mapping[0].comment"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "Publisher"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The Implementation Guide contains no examples for this profile"
            },
            "expression": [
              "StructureDefinition.where(url = 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-mamma-operation')"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-mamma-praeoperative-markierung",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-mamma-praeoperative-markierung",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 447
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-mamma-praeoperative-markierung: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62912
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-mamma-praeoperative-markierung: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-mamma-rezeptorstatus-estrogen",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-mamma-rezeptorstatus-estrogen",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 446
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-mamma-rezeptorstatus-estrogen: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 196004
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-mamma-rezeptorstatus-estrogen: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-mamma-rezeptorstatus-progesteron",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-mamma-rezeptorstatus-progesteron",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 449
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-mamma-rezeptorstatus-progesteron: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 171333
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-mamma-rezeptorstatus-progesteron: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-mamma-sozialdienst",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-mamma-sozialdienst",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 435
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-mamma-sozialdienst: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47843
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-mamma-sozialdienst: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 252250
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/bodySite'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/bodySite' to 'http://hl7.org/fhir/StructureDefinition/bodySite|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-mamma-sozialdienst: StructureDefinition.snapshot.element[152].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 284191
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_String_WS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "value should not start or finish with whitespace 'OP Komplikationen '"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-mamma-sozialdienst: StructureDefinition.snapshot.element[176].mapping[0].comment"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "Publisher"
              }
            ],
            "severity": "warning",
            "code": "business-rule",
            "details": {
              "text": "The Implementation Guide contains no examples for this profile"
            },
            "expression": [
              "StructureDefinition.where(url = 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-mamma-sozialdienst')"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-melanom-breslow-tiefe",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-melanom-breslow-tiefe",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 438
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-melanom-breslow-tiefe: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 104321
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-melanom-breslow-tiefe: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-melanom-exzision",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-melanom-exzision",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 433
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-melanom-exzision: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 29883
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-melanom-exzision: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 234198
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/bodySite'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/bodySite' to 'http://hl7.org/fhir/StructureDefinition/bodySite|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-melanom-exzision: StructureDefinition.snapshot.element[152].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 266139
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_String_WS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "value should not start or finish with whitespace 'OP Komplikationen '"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-melanom-exzision: StructureDefinition.snapshot.element[176].mapping[0].comment"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-melanom-ldh",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-melanom-ldh",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 428
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-melanom-ldh: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 97413
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-melanom-ldh: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-melanom-sicherheitsabstand",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-melanom-sicherheitsabstand",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 443
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-melanom-sicherheitsabstand: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 87162
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-melanom-sicherheitsabstand: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 92672
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "ED_INVARIANT_EXPRESSION_ERROR"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Error in constraint 'mii-onko-melanom-sicherheitsabstand-1' with expression 'valueQuantity.exists() or dataAbsentReason.exists()': Error evaluating FHIRPath expression: The name 'valueQuantity' is not valid for any of the possible types: [http://hl7.org/fhir/StructureDefinition/Observation] (@char 1)"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-melanom-sicherheitsabstand: StructureDefinition.snapshot.element[0].constraint[7]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-melanom-ulzeration",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-melanom-ulzeration",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 435
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-melanom-ulzeration: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 88901
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-melanom-ulzeration: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-nebenwirkung-adverse-event",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-nebenwirkung-adverse-event",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 443
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-nebenwirkung-adverse-event: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 146905
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-nebenwirkung-adverse-event: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-operation",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-operation",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 426
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-operation: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 180264
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-operation: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 384541
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/bodySite'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/bodySite' to 'http://hl7.org/fhir/StructureDefinition/bodySite|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-operation: StructureDefinition.snapshot.element[152].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 416482
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_String_WS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "value should not start or finish with whitespace 'OP Komplikationen '"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-operation: StructureDefinition.snapshot.element[176].mapping[0].comment"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 468438
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_String_WS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "value should not start or finish with whitespace 'OP Komplikationen '"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-operation: StructureDefinition.differential.element[21].mapping[0].comment"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-prostata-operation",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-prostata-operation",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 435
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-prostata-operation: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 29990
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-prostata-operation: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 234346
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/bodySite'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/bodySite' to 'http://hl7.org/fhir/StructureDefinition/bodySite|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-prostata-operation: StructureDefinition.snapshot.element[152].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 266287
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_String_WS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "value should not start or finish with whitespace 'OP Komplikationen '"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-prostata-operation: StructureDefinition.snapshot.element[176].mapping[0].comment"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-prostate-anzahl-positive-stanzen",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-prostate-anzahl-positive-stanzen",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 449
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-prostate-anzahl-positive-stanzen: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64680
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-prostate-anzahl-positive-stanzen: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-prostate-anzahl-stanzen",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-prostate-anzahl-stanzen",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 440
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-prostate-anzahl-stanzen: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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              {
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              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
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          }
        ]
      }
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            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-prostate-ca-befall-stanze: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
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            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
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          }
        ]
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            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
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            "expression": [
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            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-prostate-clavien-dindo: StructureDefinition.jurisdiction[0].coding[0].system"
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        ]
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    {
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            ],
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            "code": "invalid",
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            "expression": [
              "StructureDefinition/mii-pr-onko-prostate-gleason-grade-group: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
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              {
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            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-prostate-gleason-grade-group: StructureDefinition.jurisdiction[0].coding[0].system"
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          }
        ]
      }
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    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-prostate-gleason-patterns",
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              {
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
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            "code": "invalid",
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            "expression": [
              "StructureDefinition/mii-pr-onko-prostate-gleason-patterns: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
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          {
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              {
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            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
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        ]
      }
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    {
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            "expression": [
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            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
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            },
            "expression": [
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        ]
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      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-prostate-psa",
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            "expression": [
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              {
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            "severity": "warning",
            "code": "not-found",
            "details": {
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            "expression": [
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            "severity": "warning",
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            "details": {
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          {
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            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://terminology.hl7.org/ValueSet/v2-0487'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '3.0.0', found versions: 2.0.0 (from hl7.terminology.r4#6.2.0), 3.0.0 (from hl7.terminology.r4#7.1.0). Suggested fix: change the canonical reference from 'http://terminology.hl7.org/ValueSet/v2-0487' to 'http://terminology.hl7.org/ValueSet/v2-0487|3.0.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-specimen: StructureDefinition.snapshot.element[28].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 108058
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://terminology.hl7.org/ValueSet/v2-0916'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '3.0.0', found versions: 2.0.0 (from hl7.terminology.r4#6.2.0), 3.0.0 (from hl7.terminology.r4#7.1.0). Suggested fix: change the canonical reference from 'http://terminology.hl7.org/ValueSet/v2-0916' to 'http://terminology.hl7.org/ValueSet/v2-0916|3.0.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-specimen: StructureDefinition.snapshot.element[44].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 127648
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://terminology.hl7.org/ValueSet/v2-0371'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '3.0.0', found versions: 2.0.0 (from hl7.terminology.r4#6.2.0), 3.0.0 (from hl7.terminology.r4#7.1.0). Suggested fix: change the canonical reference from 'http://terminology.hl7.org/ValueSet/v2-0371' to 'http://terminology.hl7.org/ValueSet/v2-0371|3.0.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-specimen: StructureDefinition.snapshot.element[62].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 128910
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://terminology.hl7.org/ValueSet/v2-0493'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '3.0.0', found versions: 2.0.0 (from hl7.terminology.r4#6.2.0), 3.0.0 (from hl7.terminology.r4#7.1.0). Suggested fix: change the canonical reference from 'http://terminology.hl7.org/ValueSet/v2-0493' to 'http://terminology.hl7.org/ValueSet/v2-0493|3.0.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-specimen: StructureDefinition.snapshot.element[63].binding.valueSet"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-strahlentherapie-bestrahlung-nuklearmedizin",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-strahlentherapie-bestrahlung-nuklearmedizin",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 460
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-strahlentherapie-bestrahlung-nuklearmedizin: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 229804
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-strahlentherapie-bestrahlung-nuklearmedizin: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 272125
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/procedure-method'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/procedure-method' to 'http://hl7.org/fhir/StructureDefinition/procedure-method|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-strahlentherapie-bestrahlung-nuklearmedizin: StructureDefinition.snapshot.element[33].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 468943
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/bodySite'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/bodySite' to 'http://hl7.org/fhir/StructureDefinition/bodySite|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-strahlentherapie-bestrahlung-nuklearmedizin: StructureDefinition.snapshot.element[183].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 544667
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/procedure-method'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/procedure-method' to 'http://hl7.org/fhir/StructureDefinition/procedure-method|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-strahlentherapie-bestrahlung-nuklearmedizin: StructureDefinition.differential.element[1].type[0].profile[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-strahlentherapie-bestrahlung-strahlentherapie",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-strahlentherapie-bestrahlung-strahlentherapie",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 462
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-strahlentherapie-bestrahlung-strahlentherapie: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 226135
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-strahlentherapie-bestrahlung-strahlentherapie: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 312250
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/procedure-method'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/procedure-method' to 'http://hl7.org/fhir/StructureDefinition/procedure-method|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-strahlentherapie-bestrahlung-strahlentherapie: StructureDefinition.snapshot.element[73].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 463031
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/bodySite'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/bodySite' to 'http://hl7.org/fhir/StructureDefinition/bodySite|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-strahlentherapie-bestrahlung-strahlentherapie: StructureDefinition.snapshot.element[183].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 540609
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/procedure-method'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/procedure-method' to 'http://hl7.org/fhir/StructureDefinition/procedure-method|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-strahlentherapie-bestrahlung-strahlentherapie: StructureDefinition.differential.element[9].type[0].profile[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-strahlentherapie",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-strahlentherapie",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 433
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-strahlentherapie: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 125520
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-strahlentherapie: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 338991
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/bodySite'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/bodySite' to 'http://hl7.org/fhir/StructureDefinition/bodySite|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-strahlentherapie: StructureDefinition.snapshot.element[160].type[0].profile[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-studienteilnahme",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-studienteilnahme",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 433
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-studienteilnahme: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 86574
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-studienteilnahme: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-systemische-therapie-medikation",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-systemische-therapie-medikation",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 448
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-systemische-therapie-medikation: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 106798
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-systemische-therapie-medikation: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 355417
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/uv/ips/ValueSet/body-site-uv-ips'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '2.0.1', found versions: 2.0.0 (from hl7.fhir.uv.ips#2.0.0), 2.0.1 (from hl7.fhir.uv.ips#2.0.1). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/uv/ips/ValueSet/body-site-uv-ips' to 'http://hl7.org/fhir/uv/ips/ValueSet/body-site-uv-ips|2.0.1'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-systemische-therapie-medikation: StructureDefinition.snapshot.element[169].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 373761
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/uv/ips/ValueSet/medicine-route-of-administration'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '2.0.1', found versions: 2.0.0 (from hl7.fhir.uv.ips#2.0.0), 2.0.1 (from hl7.fhir.uv.ips#2.0.1). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/uv/ips/ValueSet/medicine-route-of-administration' to 'http://hl7.org/fhir/uv/ips/ValueSet/medicine-route-of-administration|2.0.1'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-systemische-therapie-medikation: StructureDefinition.snapshot.element[182].binding.valueSet"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-systemische-therapie",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-systemische-therapie",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 437
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-systemische-therapie: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 174170
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-systemische-therapie: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 407430
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/bodySite'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/bodySite' to 'http://hl7.org/fhir/StructureDefinition/bodySite|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-systemische-therapie: StructureDefinition.snapshot.element[175].type[0].profile[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-therapieempfehlung-kombinationstherapie",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-therapieempfehlung-kombinationstherapie",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 456
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-therapieempfehlung-kombinationstherapie: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 78170
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-therapieempfehlung-kombinationstherapie: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-therapieempfehlung-medikation",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-therapieempfehlung-medikation",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 446
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-therapieempfehlung-medikation: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56519
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-therapieempfehlung-medikation: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 278097
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/uv/ips/ValueSet/body-site-uv-ips'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '2.0.1', found versions: 2.0.0 (from hl7.fhir.uv.ips#2.0.0), 2.0.1 (from hl7.fhir.uv.ips#2.0.1). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/uv/ips/ValueSet/body-site-uv-ips' to 'http://hl7.org/fhir/uv/ips/ValueSet/body-site-uv-ips|2.0.1'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-therapieempfehlung-medikation: StructureDefinition.snapshot.element[153].binding.valueSet"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 296617
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/uv/ips/ValueSet/medicine-route-of-administration'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '2.0.1', found versions: 2.0.0 (from hl7.fhir.uv.ips#2.0.0), 2.0.1 (from hl7.fhir.uv.ips#2.0.1). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/uv/ips/ValueSet/medicine-route-of-administration' to 'http://hl7.org/fhir/uv/ips/ValueSet/medicine-route-of-administration|2.0.1'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-therapieempfehlung-medikation: StructureDefinition.snapshot.element[166].binding.valueSet"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-therapieempfehlung-operation",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-therapieempfehlung-operation",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 445
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-therapieempfehlung-operation: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61914
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-therapieempfehlung-operation: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-tnm-a-symbol",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-tnm-a-symbol",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 429
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tnm-a-symbol: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 79648
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tnm-a-symbol: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-tnm-klassifikation-synthetisiert",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-tnm-klassifikation-synthetisiert",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 449
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tnm-klassifikation-synthetisiert: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 95055
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tnm-klassifikation-synthetisiert: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-tnm-klassifikation",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-tnm-klassifikation",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 435
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tnm-klassifikation: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 87941
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tnm-klassifikation: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-tnm-l-kategorie",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-tnm-l-kategorie",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 432
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tnm-l-kategorie: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 84857
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tnm-l-kategorie: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-tnm-m-kategorie",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-tnm-m-kategorie",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 432
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tnm-m-kategorie: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 216032
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tnm-m-kategorie: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 222142
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "ED_INVARIANT_EXPRESSION_ERROR"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Error in constraint 'tnm-sct-uicc-konsistenz' with expression 'valueCodeableConcept.coding.where(system = 'http://snomed.info/sct').empty() or valueCodeableConcept.coding.where(system = 'http://snomed.info/sct').display.contains(iif(code.extension('https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-ex-onko-tnm-cp-praefix').exists(), code.extension('https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-ex-onko-tnm-cp-praefix').value.coding.code.first(), '') + valueCodeableConcept.coding.where(system = 'https://www.uicc.org/resources/tnm').code.first() + ' ')': Error evaluating FHIRPath expression: The name 'valueCodeableConcept' is not valid for any of the possible types: [http://hl7.org/fhir/StructureDefinition/Observation] (@char 1)"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tnm-m-kategorie: StructureDefinition.snapshot.element[0].constraint[7]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-tnm-m-symbol",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-tnm-m-symbol",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 429
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tnm-m-symbol: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 80129
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tnm-m-symbol: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-tnm-n-kategorie",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-tnm-n-kategorie",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 432
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tnm-n-kategorie: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 219916
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tnm-n-kategorie: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 226026
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "ED_INVARIANT_EXPRESSION_ERROR"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Error in constraint 'tnm-sct-uicc-konsistenz' with expression 'valueCodeableConcept.coding.where(system = 'http://snomed.info/sct').empty() or valueCodeableConcept.coding.where(system = 'http://snomed.info/sct').display.contains(iif(code.extension('https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-ex-onko-tnm-cp-praefix').exists(), code.extension('https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-ex-onko-tnm-cp-praefix').value.coding.code.first(), '') + valueCodeableConcept.coding.where(system = 'https://www.uicc.org/resources/tnm').code.first() + ' ')': Error evaluating FHIRPath expression: The name 'valueCodeableConcept' is not valid for any of the possible types: [http://hl7.org/fhir/StructureDefinition/Observation] (@char 1)"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tnm-n-kategorie: StructureDefinition.snapshot.element[0].constraint[7]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-tnm-pn-kategorie",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-tnm-pn-kategorie",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 433
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tnm-pn-kategorie: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 88969
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tnm-pn-kategorie: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-tnm-r-symbol",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-tnm-r-symbol",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 429
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tnm-r-symbol: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 79609
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tnm-r-symbol: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-tnm-s-kategorie",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-tnm-s-kategorie",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 432
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tnm-s-kategorie: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 84851
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tnm-s-kategorie: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-tnm-t-kategorie",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-tnm-t-kategorie",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 432
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tnm-t-kategorie: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 233996
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tnm-t-kategorie: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 240106
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "ED_INVARIANT_EXPRESSION_ERROR"
              }
            ],
            "severity": "error",
            "code": "invalid",
            "details": {
              "text": "Error in constraint 'tnm-sct-uicc-konsistenz' with expression 'valueCodeableConcept.coding.where(system = 'http://snomed.info/sct').empty() or valueCodeableConcept.coding.where(system = 'http://snomed.info/sct').display.contains(iif(code.extension('https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-ex-onko-tnm-cp-praefix').exists(), code.extension('https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-ex-onko-tnm-cp-praefix').value.coding.code.first(), '') + valueCodeableConcept.coding.where(system = 'https://www.uicc.org/resources/tnm').code.first() + ' ')': Error evaluating FHIRPath expression: The name 'valueCodeableConcept' is not valid for any of the possible types: [http://hl7.org/fhir/StructureDefinition/Observation] (@char 1)"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tnm-t-kategorie: StructureDefinition.snapshot.element[0].constraint[7]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-tnm-v-kategorie",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-tnm-v-kategorie",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 432
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tnm-v-kategorie: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 88603
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tnm-v-kategorie: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-tnm-y-symbol",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-tnm-y-symbol",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 429
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tnm-y-symbol: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 79720
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tnm-y-symbol: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-tod",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-tod",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 420
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tod: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 95536
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tod: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 155076
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_String_WS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "value should not start or finish with whitespace 'Todesursache ICD-Version '"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tod: StructureDefinition.snapshot.element[40].mapping[0].comment"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 156108
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_String_WS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "value should not start or finish with whitespace 'Todesursache ICD '"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tod: StructureDefinition.snapshot.element[41].mapping[0].comment"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 219344
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_String_WS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "value should not start or finish with whitespace 'Todesursache ICD-Version '"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tod: StructureDefinition.differential.element[11].mapping[0].comment"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 219530
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_String_WS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "value should not start or finish with whitespace 'Todesursache ICD '"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tod: StructureDefinition.differential.element[12].mapping[0].comment"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-tumorgroesse",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-tumorgroesse",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 429
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tumorgroesse: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 119367
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tumorgroesse: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 245185
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "The slice 'snomed' on path 'Observation.code.coding' is not marked as 'must-support' which is not consistent with the element that defines the slicing, where 'must-support' is true"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tumorgroesse: StructureDefinition.snapshot"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-tumorkonferenz",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-tumorkonferenz",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 431
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tumorkonferenz: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 156064
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tumorkonferenz: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 270572
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_String_WS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "value should not start or finish with whitespace 'Therapieabweichung aufgrund Patientenwunsch: Bei nichtangetretener oder abgebrochener Therapie ist anzugeben, ob dies dem Patientenwunsch entspricht oder ggfs. andere Gründe hat '"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tumorkonferenz: StructureDefinition.snapshot.element[86].constraint[1].human"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 370505
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_String_WS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "value should not start or finish with whitespace 'Therapieabweichung aufgrund Patientenwunsch: Bei nichtangetretener oder abgebrochener Therapie ist anzugeben, ob dies dem Patientenwunsch entspricht oder ggfs. andere Gründe hat '"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tumorkonferenz: StructureDefinition.differential.element[16].constraint[0].human"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 366519
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "The slice 'obds' on path 'CarePlan.activity' is not marked as 'must-support' which is not consistent with the element that defines the slicing, where 'must-support' is true"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tumorkonferenz: StructureDefinition.snapshot"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 366519
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "The slice 'extended' on path 'CarePlan.activity' is not marked as 'must-support' which is not consistent with the element that defines the slicing, where 'must-support' is true"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tumorkonferenz: StructureDefinition.snapshot"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-tumormarker",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-tumormarker",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 428
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tumormarker: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 35353
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tumormarker: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 184423
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/extension-quantity-translation'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/extension-quantity-translation' to 'http://hl7.org/fhir/StructureDefinition/extension-quantity-translation|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tumormarker: StructureDefinition.snapshot.element[88].type[0].profile[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 189920
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "TYPE_SPECIFIC_CHECKS_DT_CANONICAL_MULTIPLE_POSSIBLE_VERSIONS"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "There are multiple different potential matches for the url 'http://hl7.org/fhir/StructureDefinition/quantity-precision'. It might be a good idea to fix to the correct version to reduce the likelihood of a wrong version being selected by an implementation/implementer, or use the [IG Parameter `pin-canonicals`](https://hl7.org/fhir/tools/CodeSystem-ig-parameters.html). Using version '5.3.0', found versions: 4.0.1 (from hl7.fhir.r4.core#4.0.1), 5.1.0 (from hl7.fhir.uv.extensions.r4#5.1.0), 5.2.0 (from hl7.fhir.uv.extensions.r4#5.2.0), 5.3.0 (from hl7.fhir.uv.extensions.r4#5.3.0). Suggested fix: change the canonical reference from 'http://hl7.org/fhir/StructureDefinition/quantity-precision' to 'http://hl7.org/fhir/StructureDefinition/quantity-precision|5.3.0'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-tumormarker: StructureDefinition.snapshot.element[92].type[0].profile[0]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-verlauf",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-verlauf",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 424
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-verlauf: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 242706
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-verlauf: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 485358
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "The slice 'valueCodeableConcept' on path 'Observation.value[x]' is not marked as 'must-support' which is not consistent with the element that defines the slicing, where 'must-support' is true"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-verlauf: StructureDefinition.snapshot"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/StructureDefinition-mii-pr-onko-weitere-klassifikationen",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "StructureDefinition-mii-pr-onko-weitere-klassifikationen",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 441
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-weitere-klassifikationen: StructureDefinition.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 88407
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablestructuredefinition|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "StructureDefinition/mii-pr-onko-weitere-klassifikationen: StructureDefinition.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-allgemeiner-leistungszustand-ecog-loinc",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-allgemeiner-leistungszustand-ecog-loinc",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 445
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-allgemeiner-leistungszustand-ecog-loinc: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8929
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-allgemeiner-leistungszustand-ecog-loinc: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9289
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA9623-5' is not valid in the system http://loinc.org (error: [a8e9490e-665c-41e4-a764-9bfcf04adc47]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-allgemeiner-leistungszustand-ecog-loinc: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9448
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA9624-3' is not valid in the system http://loinc.org (error: [f891b4ff-ccc4-441a-b1d7-14434cec6c27]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-allgemeiner-leistungszustand-ecog-loinc: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9569
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA9625-0' is not valid in the system http://loinc.org (error: [d32aeb70-4874-4aad-987a-49f8a187518b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-allgemeiner-leistungszustand-ecog-loinc: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9685
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA9626-8' is not valid in the system http://loinc.org (error: [8554b721-9885-4a35-b83e-78abe87b41d5]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-allgemeiner-leistungszustand-ecog-loinc: ValueSet.compose.include[0].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9722
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA9627-6' is not valid in the system http://loinc.org (error: [3249a6ac-654c-4194-82f4-37a988055dad]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-allgemeiner-leistungszustand-ecog-loinc: ValueSet.compose.include[0].concept[5]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-allgemeiner-leistungszustand-ecog",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-allgemeiner-leistungszustand-ecog",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 439
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-allgemeiner-leistungszustand-ecog: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6935
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-allgemeiner-leistungszustand-ecog: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-allgemeiner-leistungszustand-karnofsky-loinc",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-allgemeiner-leistungszustand-karnofsky-loinc",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 450
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-allgemeiner-leistungszustand-karnofsky-loinc: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9975
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-allgemeiner-leistungszustand-karnofsky-loinc: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10219
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA29176-7' is not valid in the system http://loinc.org (error: [4ea1ffd5-4ec8-4437-b8dd-23d284ba9f9f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-allgemeiner-leistungszustand-karnofsky-loinc: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10315
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA29177-5' is not valid in the system http://loinc.org (error: [eed7e314-d4f1-4f3a-8a80-79f9a792fdac]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-allgemeiner-leistungszustand-karnofsky-loinc: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10417
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA29178-3' is not valid in the system http://loinc.org (error: [87299a7e-acc0-47db-b402-d35c72b60b8b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-allgemeiner-leistungszustand-karnofsky-loinc: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10516
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA29179-1' is not valid in the system http://loinc.org (error: [a414468a-32a3-42e7-887d-37ce25fdc3f0]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-allgemeiner-leistungszustand-karnofsky-loinc: ValueSet.compose.include[0].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10608
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA29180-9' is not valid in the system http://loinc.org (error: [7c7f27e2-e9ad-44b9-8058-eb34f8dce24a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-allgemeiner-leistungszustand-karnofsky-loinc: ValueSet.compose.include[0].concept[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10688
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA29181-7' is not valid in the system http://loinc.org (error: [10c6a6f1-b153-48a3-b3e4-e759d986c1cb]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-allgemeiner-leistungszustand-karnofsky-loinc: ValueSet.compose.include[0].concept[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10798
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA29182-5' is not valid in the system http://loinc.org (error: [63554c15-6e1a-4922-92b8-0f4d3f7cbcc8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-allgemeiner-leistungszustand-karnofsky-loinc: ValueSet.compose.include[0].concept[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10907
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA29183-3' is not valid in the system http://loinc.org (error: [2a25cf8a-692f-40db-9160-a9cea2237621]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-allgemeiner-leistungszustand-karnofsky-loinc: ValueSet.compose.include[0].concept[8]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10986
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA29184-1' is not valid in the system http://loinc.org (error: [97ff115d-ee20-4e3a-9e78-1a65693cc34b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-allgemeiner-leistungszustand-karnofsky-loinc: ValueSet.compose.include[0].concept[9]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11023
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA9627-6' is not valid in the system http://loinc.org (error: [5f8c297f-8e5a-4867-b1da-e7ed49d15ced]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-allgemeiner-leistungszustand-karnofsky-loinc: ValueSet.compose.include[0].concept[10]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-allgemeiner-leistungszustand-karnofsky",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-allgemeiner-leistungszustand-karnofsky",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 444
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-allgemeiner-leistungszustand-karnofsky: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7010
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-allgemeiner-leistungszustand-karnofsky: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-asa-loinc",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-asa-loinc",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 415
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-asa-loinc: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7663
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-asa-loinc: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7765
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA28813-6' is not valid in the system http://loinc.org (Wrong Display Name 'ASA I' for http://loinc.org#LA28813-6. Valid display is 'My doctor told me to stop taking aspirin because of GI upset' (en) (for the language(s) 'en'))"
            },
            "expression": [
              "ValueSet/mii-vs-onko-asa-loinc: ValueSet.compose.include[0].concept[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7805
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA28814-4' is not valid in the system http://loinc.org (error: [8001d98b-0971-4599-8306-3161fb426052]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-asa-loinc: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7846
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA28815-1' is not valid in the system http://loinc.org (error: [c09cec43-284d-44b6-b949-81c0d099e2f5]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-asa-loinc: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7886
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA28816-9' is not valid in the system http://loinc.org (error: [ec8426c7-f406-407d-9c66-424c489c4df3]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-asa-loinc: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7925
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA28817-7' is not valid in the system http://loinc.org (error: [c5c8839f-c5eb-49eb-b50a-c997cf966366]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-asa-loinc: ValueSet.compose.include[0].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7965
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA28818-5' is not valid in the system http://loinc.org (error: [47f0bab9-5ee5-4e23-8c95-e4b6e17d6fd7]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-asa-loinc: ValueSet.compose.include[0].concept[5]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-asa-obds",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-asa-obds",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 414
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-asa-obds: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6648
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-asa-obds: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-beurteilung-lokaler-residualstatus",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-beurteilung-lokaler-residualstatus",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 440
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-beurteilung-lokaler-residualstatus: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6868
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-beurteilung-lokaler-residualstatus: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-fernmetastasen",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-fernmetastasen",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 420
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-fernmetastasen: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6636
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-fernmetastasen: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-genetische-variante-auspraegung",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-genetische-variante-auspraegung",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 437
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
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            ],
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            ],
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            },
            "expression": [
              "ValueSet/mii-vs-onko-icdo3-topographie: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6925
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-icdo3-topographie: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-ighv-gensegmente-hgnc",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-ighv-gensegmente-hgnc",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 427
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-ighv-gensegmente-hgnc: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70766
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-ighv-gensegmente-hgnc: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-kdl-dokumentklassen",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-kdl-dokumentklassen",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 425
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-kdl-dokumentklassen: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39985
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-kdl-dokumentklassen: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-koerperstruktur-sct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-koerperstruktur-sct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 425
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-koerperstruktur-sct: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6300
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-koerperstruktur-sct: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-krk-abstand-circumferelle-resektionsrand",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-krk-abstand-circumferelle-resektionsrand",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 446
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-krk-abstand-circumferelle-resektionsrand: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7596
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-krk-abstand-circumferelle-resektionsrand: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7891
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '81184-4' is not valid in the system http://loinc.org (error: [5ca46800-cded-4039-8292-7fb218965018]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-krk-abstand-circumferelle-resektionsrand: ValueSet.compose.include[0].concept[1]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-krk-abstand-resektionslinie-aboral",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-krk-abstand-resektionslinie-aboral",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 440
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-krk-abstand-resektionslinie-aboral: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7509
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-krk-abstand-resektionslinie-aboral: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7793
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '81183-6' is not valid in the system http://loinc.org (error: [def771b3-4ca5-4e89-b53e-1dee6bdb1dd5]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-krk-abstand-resektionslinie-aboral: ValueSet.compose.include[0].concept[1]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-krk-anastomoseninsuffizienz",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-krk-anastomoseninsuffizienz",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 433
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-krk-anastomoseninsuffizienz: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6857
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-krk-anastomoseninsuffizienz: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-krk-mrt-mesorektale-faszie-status",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-krk-mrt-mesorektale-faszie-status",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 439
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-krk-mrt-mesorektale-faszie-status: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6991
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-krk-mrt-mesorektale-faszie-status: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-krk-stoma-anzeichnung",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-krk-stoma-anzeichnung",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 427
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-krk-stoma-anzeichnung: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6787
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-krk-stoma-anzeichnung: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-krk-stoma-status-reason",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-krk-stoma-status-reason",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 429
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-krk-stoma-status-reason: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7648
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-krk-stoma-status-reason: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8233
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '262008008' is not valid in the system http://snomed.info/sct (error: [0ed6c42d-8f47-4d7e-a963-8d5abccb98c0]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-krk-stoma-status-reason: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8274
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '261665006' is not valid in the system http://snomed.info/sct (error: [c93ef42e-e01f-4b03-aad5-b5a51c3389ec]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-krk-stoma-status-reason: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8338
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '373068000' is not valid in the system http://snomed.info/sct (error: [b1916405-a160-4ce5-b069-0427e84700f9]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-krk-stoma-status-reason: ValueSet.compose.include[0].concept[3]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-krk-tme-qualitaet",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-krk-tme-qualitaet",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 423
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-krk-tme-qualitaet: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6756
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-krk-tme-qualitaet: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-mamma-faerbeintensitaet",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-mamma-faerbeintensitaet",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 429
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-faerbeintensitaet: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7308
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-faerbeintensitaet: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7450
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA6751-7' is not valid in the system http://loinc.org (error: [fd7b1ac1-1e03-40d4-9a4f-57dc516af3dd]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-faerbeintensitaet: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7490
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA14974-2' is not valid in the system http://loinc.org (error: [df0ee479-39bb-43e2-b98e-fafa8f5c813f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-faerbeintensitaet: ValueSet.compose.include[0].concept[2]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-mamma-her2neu-ihc-score",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-mamma-her2neu-ihc-score",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 429
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-her2neu-ihc-score: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7616
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-her2neu-ihc-score: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7749
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA11841-6' is not valid in the system http://loinc.org (error: [70b8dc92-1b98-46d0-b711-3ac3a20d68d0]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-her2neu-ihc-score: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7785
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA11842-4' is not valid in the system http://loinc.org (error: [54c813fc-43e8-43e8-8190-f1111f687198]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-her2neu-ihc-score: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7821
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA11843-2' is not valid in the system http://loinc.org (error: [65454dbf-bbc8-4294-b4c2-c22d8cd14e79]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-her2neu-ihc-score: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7868
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA11884-6' is not valid in the system http://loinc.org (error: [4a11dd70-5ce4-4995-b722-6d5dc51ff709]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-her2neu-ihc-score: ValueSet.compose.include[0].concept[4]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-mamma-her2neu-status-leitlinie",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-mamma-her2neu-status-leitlinie",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 436
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-her2neu-status-leitlinie: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6887
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-her2neu-status-leitlinie: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-mamma-her2neu-status-obds",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-mamma-her2neu-status-obds",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 431
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-her2neu-status-obds: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6785
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-her2neu-status-obds: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-mamma-intraoperatives-imaging-praeparat",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-mamma-intraoperatives-imaging-praeparat",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 445
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-intraoperatives-imaging-praeparat: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6788
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-intraoperatives-imaging-praeparat: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-mamma-ish-ergebnis",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-mamma-ish-ergebnis",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 424
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-ish-ergebnis: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7232
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-ish-ergebnis: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7377
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA6577-6' is not valid in the system http://loinc.org (error: [323e2a0a-e200-42c2-857f-6aada0458e13]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-ish-ergebnis: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7420
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA11885-3' is not valid in the system http://loinc.org (error: [e2b82b4d-5066-4031-8fe7-05fdb4f1ecfa]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-ish-ergebnis: ValueSet.compose.include[0].concept[2]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-mamma-menopause-status",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-mamma-menopause-status",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 428
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-menopause-status: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7394
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-menopause-status: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7970
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '76498008' is not valid in the system http://snomed.info/sct (error: [64d1ada7-9489-43b8-bb72-1bdf6511eb38]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-menopause-status: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8029
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '261665006' is not valid in the system http://snomed.info/sct (error: [bd5f93fb-10fa-4f3f-8505-91e9b89cdba4]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-menopause-status: ValueSet.compose.include[0].concept[2]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-mamma-operation-ops",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-mamma-operation-ops",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 425
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-operation-ops: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6496
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-operation-ops: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-mamma-operation-sct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-mamma-operation-sct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 425
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-operation-sct: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7904
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-operation-sct: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-mamma-praeoperative-markierung-modalitaet",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-mamma-praeoperative-markierung-modalitaet",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 447
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-praeoperative-markierung-modalitaet: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8289
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-praeoperative-markierung-modalitaet: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8956
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '433222002' is not valid in the system http://snomed.info/sct (error: [03a66cad-8c36-4810-8f35-227d388ab98c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-praeoperative-markierung-modalitaet: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9066
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '836381000000102' is not valid in the system http://snomed.info/sct (error: [b727c08f-e543-4b5d-9377-c6d4d938d348]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-praeoperative-markierung-modalitaet: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9204
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '911831000000104' is not valid in the system http://snomed.info/sct (error: [9e068ad3-9a42-4ffb-a771-2beb2ecae12d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-praeoperative-markierung-modalitaet: ValueSet.compose.include[0].concept[3]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-mamma-rezeptorstatus-leitlinie",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-mamma-rezeptorstatus-leitlinie",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 436
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-rezeptorstatus-leitlinie: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6856
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-rezeptorstatus-leitlinie: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-mamma-rezeptorstatus-obds",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-mamma-rezeptorstatus-obds",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 431
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-rezeptorstatus-obds: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7234
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-rezeptorstatus-obds: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7379
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA6577-6' is not valid in the system http://loinc.org (error: [1cf66fb8-419f-4146-b7e1-f28f9706d222]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-rezeptorstatus-obds: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7419
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LA4489-6' is not valid in the system http://loinc.org (error: [e0a4290a-3bf4-4654-82d4-2a843cef67d0]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-mamma-rezeptorstatus-obds: ValueSet.compose.include[0].concept[2]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-marker-gene-hgnc",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-marker-gene-hgnc",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 422
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-marker-gene-hgnc: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21189
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-marker-gene-hgnc: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-melanom-exzision-snomedct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-melanom-exzision-snomedct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 431
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-melanom-exzision-snomedct: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7100
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-melanom-exzision-snomedct: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-melanom-ldh",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-melanom-ldh",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 417
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-melanom-ldh: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7601
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-melanom-ldh: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7895
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '14804-9' is not valid in the system http://loinc.org (error: [a85276d3-f8d4-4966-95bb-0527436e66f2]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-melanom-ldh: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8027
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '14805-6' is not valid in the system http://loinc.org (error: [bfe9bf54-0aa2-4c23-84b8-f22e5cd73096]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-melanom-ldh: ValueSet.compose.include[0].concept[2]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-melanom-ulzeration",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-melanom-ulzeration",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 424
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-melanom-ulzeration: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7697
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-melanom-ulzeration: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-nebenwirkung-art",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-nebenwirkung-art",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 422
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-nebenwirkung-art: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 254729
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-nebenwirkung-art: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-nebenwirkung-ctcae-grad",
      "resource": {
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            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'http://www.orpha.net'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 13857
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '116' is not valid in the system http://www.orpha.net (error: [3e022439-1fca-49c9-8619-81bd15bfae1e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 13899
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '125' is not valid in the system http://www.orpha.net (error: [4116e8ac-48a4-4407-911a-b81be9a48034]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 13951
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '97297' is not valid in the system http://www.orpha.net (error: [c812bf1d-ea0f-45b1-8104-e54538fe1c32]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14049
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '363972' is not valid in the system http://www.orpha.net (error: [6b4128d4-80cb-44e4-b414-f8e58e1be8c1]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14112
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '319465' is not valid in the system http://www.orpha.net (error: [136ae667-70f1-43c6-b904-d3e268b7982d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14180
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '626' is not valid in the system http://www.orpha.net (error: [516ead0e-613d-4cf4-926a-e983e33e54dc]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14261
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '252202' is not valid in the system http://www.orpha.net (error: [76f46f6f-3e3b-4768-8517-0ddeaac4917d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14307
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '3071' is not valid in the system http://www.orpha.net (error: [c6217e7e-dfe4-49ea-b3da-f89e4494d902]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[8]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14356
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1553' is not valid in the system http://www.orpha.net (error: [df08e5c2-fdcf-4df4-83ca-bf1b18c8d649]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[9]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14407
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '124' is not valid in the system http://www.orpha.net (error: [9bf98ca1-cc91-46dd-8609-c32cc731f656]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[10]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14474
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '284343' is not valid in the system http://www.orpha.net (error: [770457c8-bc29-46dd-9480-f489e6bd107c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[11]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14515
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '870' is not valid in the system http://www.orpha.net (error: [67846b62-3e1a-4f11-b53e-3b5a7d7e2379]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[12]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14573
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '733' is not valid in the system http://www.orpha.net (error: [6dbe1e8d-f458-4341-87f7-30725c8057e7]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[13]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14614
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '84' is not valid in the system http://www.orpha.net (error: [21581dbc-6ad2-4688-9f74-64df0e6fe370]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[14]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14714
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '404476' is not valid in the system http://www.orpha.net (error: [08f94725-9e37-40a5-bfe2-ab90c16d7dbc]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[15]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14757
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '377' is not valid in the system http://www.orpha.net (error: [7705c00a-c1e4-42de-bc89-041727e11669]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[16]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14828
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '29072' is not valid in the system http://www.orpha.net (error: [cc9f6563-8e5d-41a4-98d0-53fa6d736eb6]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[17]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14884
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '357027' is not valid in the system http://www.orpha.net (error: [20c71b07-5030-47e8-ae45-8ea274689cf9]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[18]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14940
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '2929' is not valid in the system http://www.orpha.net (error: [cf25be1b-6492-4957-b94c-67e53200d9ad]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[19]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14988
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '524' is not valid in the system http://www.orpha.net (error: [efddb58d-6712-4035-a20f-4f3b7d290fa3]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[20]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15030
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '144' is not valid in the system http://www.orpha.net (error: [91010ce7-7fb1-4c46-889c-f8184fe7a8f8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[21]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15092
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '634461' is not valid in the system http://www.orpha.net (error: [c55ce4c0-3e9a-422f-b6da-81cc0a02090e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[22]"
            ]
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          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
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              {
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                "valueString": "InstanceValidator"
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              {
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                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1052' is not valid in the system http://www.orpha.net (error: [b8e79a5b-b1af-4eb7-8e5b-e76b21b73fad]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[23]"
            ]
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          {
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              {
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              {
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                "valueInteger": 15202
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
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                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '2576' is not valid in the system http://www.orpha.net (error: [129c195d-2890-4964-9a94-058be973de82]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[24]"
            ]
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          {
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              {
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                "valueInteger": 15265
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '652' is not valid in the system http://www.orpha.net (error: [33599530-fd2a-4ad0-be00-9d21327d33ae]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[25]"
            ]
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          {
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15332
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
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                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '247698' is not valid in the system http://www.orpha.net (error: [be74d330-5793-4453-87d1-a961de2fbb48]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[26]"
            ]
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          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15399
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '247709' is not valid in the system http://www.orpha.net (error: [832365e3-475f-4bde-ba99-8c689271e14e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[27]"
            ]
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          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15451
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '636' is not valid in the system http://www.orpha.net (error: [9ebdf804-9c45-4f95-812c-41f0d77030f9]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[28]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15505
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '647' is not valid in the system http://www.orpha.net (error: [5c34da3b-63f3-4a7a-9f6b-b4b95c3772bb]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[29]"
            ]
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          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15548
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '648' is not valid in the system http://www.orpha.net (error: [ea69fd5b-600e-430e-8ba5-704c93dc6ac7]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[30]"
            ]
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          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15590
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '296' is not valid in the system http://www.orpha.net (error: [b0cd9e95-c84c-499e-8dbd-ab7f4c3af222]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[31]"
            ]
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          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15638
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '163634' is not valid in the system http://www.orpha.net (error: [dab3a075-3c45-4c3d-bf95-1a9beac4c3e5]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[32]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15713
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '2780' is not valid in the system http://www.orpha.net (error: [7d456f20-b402-4e62-b763-cea2973dd894]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[33]"
            ]
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          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15796
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '324299' is not valid in the system http://www.orpha.net (error: [70230c0e-4e8e-4533-9c0e-f3ec7ae1fcd8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[34]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15841
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '2849' is not valid in the system http://www.orpha.net (error: [1d8e34b4-d4a1-4627-8a97-3833f5acd44f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[35]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15892
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '2869' is not valid in the system http://www.orpha.net (error: [5082fd77-6f43-4a33-805c-ae24960bc7d7]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[36]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 15963
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '661' is not valid in the system http://www.orpha.net (error: [c8aee865-195e-4d6b-bf32-0c3525c90aba]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[37]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16028
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '530313' is not valid in the system http://www.orpha.net (error: [30c7375b-398d-4a5f-bfbf-3117e20112e7]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[38]"
            ]
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          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16088
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '306498' is not valid in the system http://www.orpha.net (error: [3152d64f-55a5-4ad5-b7d4-44904793ce77]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[39]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16157
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '231108' is not valid in the system http://www.orpha.net (error: [f35aec6a-794e-43db-844a-74a7fc9182ed]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[40]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16211
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '2909' is not valid in the system http://www.orpha.net (error: [274a6fc5-7022-453f-aa89-ccb0a954b422]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[41]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16302
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '71290' is not valid in the system http://www.orpha.net (error: [05d566ad-80d8-49e8-8492-33088cac502a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[42]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16348
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '494433' is not valid in the system http://www.orpha.net (error: [9a94a45d-073a-48b2-9d82-9b3e96035ba1]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[43]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16405
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '2585' is not valid in the system http://www.orpha.net (error: [6f8716c7-f853-4def-8421-26b9890b58d2]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[44]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16464
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '42738' is not valid in the system http://www.orpha.net (error: [e79a3738-d11c-4fd1-8240-587e33fc6571]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[45]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16522
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '373' is not valid in the system http://www.orpha.net (error: [05515c3c-50ca-4841-b813-8db3c2e2cee6]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[46]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16564
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '821' is not valid in the system http://www.orpha.net (error: [db18f1e0-936d-4dc8-b9d8-91ef488ab440]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[47]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16615
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1775' is not valid in the system http://www.orpha.net (error: [ff2f7c23-f1ca-4c07-bf16-07f04e5dae4a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[48]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16663
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '3380' is not valid in the system http://www.orpha.net (error: [7b9907fe-d52f-4e7c-b7c0-9c4e8e0f95ff]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[49]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16717
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '805' is not valid in the system http://www.orpha.net (error: [12453988-f966-43bd-a6b5-3166658eeb90]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[50]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16770
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '892' is not valid in the system http://www.orpha.net (error: [f31b2a03-a001-4d1f-b05a-9a377b206d05]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[51]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16811
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '893' is not valid in the system http://www.orpha.net (error: [887fdaf8-029e-4077-bbf6-4b5c52c9d023]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[52]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16855
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '3447' is not valid in the system http://www.orpha.net (error: [5893010d-3365-4327-aaae-785e19564869]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[53]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16904
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '910' is not valid in the system http://www.orpha.net (error: [cdcfa17e-16bf-49ea-b8e6-d7862ac2eab2]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-praedispositionssyndrome-orpha: ValueSet.compose.include[0].concept[54]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-primaertumor-diagnosesicherung",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-primaertumor-diagnosesicherung",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 436
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-primaertumor-diagnosesicherung: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6916
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-primaertumor-diagnosesicherung: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-prostata-clavien-dindo",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-prostata-clavien-dindo",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 428
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-clavien-dindo: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9100
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-clavien-dindo: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9714
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1367520006' is not valid in the system http://snomed.info/sct (error: [0bba937a-933f-47a4-888b-71e7c584c863]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-clavien-dindo: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9797
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1367521005' is not valid in the system http://snomed.info/sct (error: [f2dd5526-1cc8-4bbb-ae55-1377ed1a9bd4]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-clavien-dindo: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9881
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1367522003' is not valid in the system http://snomed.info/sct (error: [515b7c53-1822-43d0-85b5-7a79ad669745]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-clavien-dindo: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9965
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1367523008' is not valid in the system http://snomed.info/sct (error: [eddfbb72-d8d1-409d-9cc6-c05083dd4d3a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-clavien-dindo: ValueSet.compose.include[0].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10047
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1367524002' is not valid in the system http://snomed.info/sct (error: [b3317af0-61be-4da6-b486-299b87bae14f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-clavien-dindo: ValueSet.compose.include[0].concept[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10130
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1367525001' is not valid in the system http://snomed.info/sct (error: [ac12e24f-637d-4b43-b9be-aad224c94621]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-clavien-dindo: ValueSet.compose.include[0].concept[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10213
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1367526000' is not valid in the system http://snomed.info/sct (error: [5687c0d6-4882-412c-94a6-4cf49d89189e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-clavien-dindo: ValueSet.compose.include[0].concept[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10294
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1367527009' is not valid in the system http://snomed.info/sct (error: [0dcfc364-1a98-4c97-bd62-7f6a70f10e8b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-clavien-dindo: ValueSet.compose.include[0].concept[8]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-prostata-gleason-pattern-loinc",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-prostata-gleason-pattern-loinc",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 436
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-gleason-pattern-loinc: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7661
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-gleason-pattern-loinc: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7872
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '44642-7' is not valid in the system http://loinc.org (error: [4c6819f2-a120-4ca9-9ba6-fa745bf0400d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-gleason-pattern-loinc: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7946
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '44643-5' is not valid in the system http://loinc.org (error: [ec776a4f-7474-4ad4-8b2b-11bb0ba36571]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-gleason-pattern-loinc: ValueSet.compose.include[0].concept[2]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-prostata-gleason-patterns",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-prostata-gleason-patterns",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 431
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-gleason-patterns: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7959
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-gleason-patterns: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8512
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '369771005' is not valid in the system http://snomed.info/sct (error: [9b4d0455-0ede-4d1b-9708-6340a1f42362]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-gleason-patterns: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8563
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '369772003' is not valid in the system http://snomed.info/sct (error: [1bd43420-8479-4387-820b-cdc85daa8f53]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-gleason-patterns: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8614
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '369773008' is not valid in the system http://snomed.info/sct (error: [745d5a98-07c4-4ab2-a3d9-285690e3ec6c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-gleason-patterns: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8665
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '369774002' is not valid in the system http://snomed.info/sct (error: [4e49445b-6f52-49cf-9fc3-53c1b7eeaff8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-gleason-patterns: ValueSet.compose.include[0].concept[4]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-prostata-gleason-primary-secondary-tertiary",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-prostata-gleason-primary-secondary-tertiary",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 449
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-gleason-primary-secondary-tertiary: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8050
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-gleason-primary-secondary-tertiary: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8657
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '384995005' is not valid in the system http://snomed.info/sct (error: [1b84b93b-40c1-4f94-8064-a5eda79a0f61]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-gleason-primary-secondary-tertiary: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8735
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '385002007' is not valid in the system http://snomed.info/sct (error: [99630287-d549-477c-a20f-f78973a48428]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-gleason-primary-secondary-tertiary: ValueSet.compose.include[0].concept[2]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-prostata-gleason-score-gesamt",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-prostata-gleason-score-gesamt",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 435
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-gleason-score-gesamt: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9540
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-gleason-score-gesamt: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10139
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '46677009' is not valid in the system http://snomed.info/sct (error: [7fb2b5ae-4a45-43e5-92be-fbf344037636]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-gleason-score-gesamt: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10213
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '18430005' is not valid in the system http://snomed.info/sct (error: [9f108071-cb8c-43e4-b5d3-9b7292f46314]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-gleason-score-gesamt: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10287
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '74013009' is not valid in the system http://snomed.info/sct (error: [fff453d9-c52d-4764-9569-8c965c8777b1]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-gleason-score-gesamt: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10361
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '84556003' is not valid in the system http://snomed.info/sct (error: [fd81b5e5-1506-4ddf-8f14-2d4927d13dbf]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-gleason-score-gesamt: ValueSet.compose.include[0].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10435
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '57403001' is not valid in the system http://snomed.info/sct (error: [2c329424-613d-47ea-b50a-8d631e14c8dc]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-gleason-score-gesamt: ValueSet.compose.include[0].concept[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10509
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '33013007' is not valid in the system http://snomed.info/sct (error: [7e013e23-e23d-4792-b6c4-d3cf6a8330c6]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-gleason-score-gesamt: ValueSet.compose.include[0].concept[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10583
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '58925000' is not valid in the system http://snomed.info/sct (error: [c10a7101-89d3-4b4e-a576-0707244dc006]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-gleason-score-gesamt: ValueSet.compose.include[0].concept[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10658
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '24514009' is not valid in the system http://snomed.info/sct (error: [8b06b3ed-fd1f-49bc-8868-e3ac75c45d1c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-gleason-score-gesamt: ValueSet.compose.include[0].concept[8]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-prostata-gleason-score",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-prostata-gleason-score",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 428
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-gleason-score: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10401
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-gleason-score: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11128
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1279714001' is not valid in the system http://snomed.info/sct (error: [e880f251-296d-4819-b310-64ff3a500e6f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-gleason-score: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11266
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1279716004' is not valid in the system http://snomed.info/sct (error: [463e5e82-2be4-4d34-8048-3057447f7824]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-gleason-score: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11404
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1279718003' is not valid in the system http://snomed.info/sct (error: [c4c33860-29dd-4365-b787-342acfb04159]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-gleason-score: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11542
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1279717008' is not valid in the system http://snomed.info/sct (error: [ca75d397-2508-46ac-9f74-e951f16d0ea4]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-gleason-score: ValueSet.compose.include[0].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11680
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1279719006' is not valid in the system http://snomed.info/sct (error: [49e39d98-004c-48c3-972b-96b473d93cb6]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-gleason-score: ValueSet.compose.include[0].concept[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11818
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1279720000' is not valid in the system http://snomed.info/sct (error: [5f4397ea-0087-4261-9aa6-097dcd70c2eb]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-gleason-score: ValueSet.compose.include[0].concept[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 11956
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1279721001' is not valid in the system http://snomed.info/sct (error: [c1257e3a-3ff1-497f-a155-f80dd68cb2f0]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-gleason-score: ValueSet.compose.include[0].concept[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 12095
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1279722008' is not valid in the system http://snomed.info/sct (error: [f6955535-990e-4c39-9ddd-040e1d5874cd]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-gleason-score: ValueSet.compose.include[0].concept[8]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-prostata-operation-snomedct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-prostata-operation-snomedct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 433
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-operation-snomedct: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7820
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-operation-snomedct: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-prostata-postsurgical-complications",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-prostata-postsurgical-complications",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 441
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-postsurgical-complications: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6929
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-postsurgical-complications: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-prostata-psa-loinc",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-prostata-psa-loinc",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 424
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-psa-loinc: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7961
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-psa-loinc: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8061
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '10886-0' is not valid in the system http://loinc.org (error: [080eba26-5a35-4b24-bcee-c60105d2e074]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-psa-loinc: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8080
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '83113-1' is not valid in the system http://loinc.org (error: [1e61b866-3070-42b4-8d17-ee3d3b4c360f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-psa-loinc: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8099
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '35741-8' is not valid in the system http://loinc.org (error: [cb3d18fa-7c48-460e-921a-a19b262289ea]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-psa-loinc: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8118
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '83112-3' is not valid in the system http://loinc.org (error: [02b0ad63-e3fb-4f33-88e6-e2d548e03b36]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-prostata-psa-loinc: ValueSet.compose.include[0].concept[4]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-seitenlokalisation",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-seitenlokalisation",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 424
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-seitenlokalisation: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6742
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-seitenlokalisation: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-strahlentherapie-applikationsart",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-strahlentherapie-applikationsart",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 438
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-strahlentherapie-applikationsart: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6933
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-strahlentherapie-applikationsart: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-strahlentherapie-boost",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-strahlentherapie-boost",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 428
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-strahlentherapie-boost: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6783
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-strahlentherapie-boost: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-strahlentherapie-ende-grund",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-strahlentherapie-ende-grund",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 433
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-strahlentherapie-ende-grund: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9506
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-strahlentherapie-ende-grund: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-strahlentherapie-intention",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-strahlentherapie-intention",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 432
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-strahlentherapie-intention: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8211
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-strahlentherapie-intention: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-strahlentherapie-stellungzurop",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-strahlentherapie-stellungzurop",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 436
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-strahlentherapie-stellungzurop: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6852
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-strahlentherapie-stellungzurop: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-strahlentherapie-strahlenart",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-strahlentherapie-strahlenart",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 434
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-strahlentherapie-strahlenart: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6871
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-strahlentherapie-strahlenart: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-strahlentherapie-strahlungseinheit",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-strahlentherapie-strahlungseinheit",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 440
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-strahlentherapie-strahlungseinheit: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7159
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-strahlentherapie-strahlungseinheit: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7291
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'kBq' is not valid in the system http://unitsofmeasure.org (error: [f80b827e-e1f9-4588-bea1-8851670d7689]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-strahlentherapie-strahlungseinheit: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7322
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'MBq' is not valid in the system http://unitsofmeasure.org (error: [b0cc688e-99d4-40e3-a740-df452d54b683]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-strahlentherapie-strahlungseinheit: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7353
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'GBq' is not valid in the system http://unitsofmeasure.org (error: [8b298231-2fc4-4705-bbaa-8c6defb69d97]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-strahlentherapie-strahlungseinheit: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "warning",
            "code": "exception",
            "details": {
              "text": "Error from http://127.0.0.1:8090/fhir: Error: [237d3a83-4105-4b44-a799-c9834a63925b]: A usable code system with URL http://unitsofmeasure.org|3.0.1 could not be resolved.\r\nInformation: X-Request-Id: 7212c981-a838-4512-a9e2-4f98295bd3f7"
            },
            "expression": [
              "ValueSet.where(id = 'mii-vs-onko-strahlentherapie-strahlungseinheit')"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "warning",
            "code": "exception",
            "details": {
              "text": "Error from http://127.0.0.1:8090/fhir: Error: [237d3a83-4105-4b44-a799-c9834a63925b]: A usable code system with URL http://unitsofmeasure.org|3.0.1 could not be resolved.\r\nInformation: X-Request-Id: 7212c981-a838-4512-a9e2-4f98295bd3f7"
            },
            "expression": [
              "ValueSet.where(id = 'mii-vs-onko-strahlentherapie-strahlungseinheit')"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              }
            ],
            "severity": "warning",
            "code": "exception",
            "details": {
              "text": "Error from http://127.0.0.1:8090/fhir: Error: [237d3a83-4105-4b44-a799-c9834a63925b]: A usable code system with URL http://unitsofmeasure.org|3.0.1 could not be resolved.\r\nInformation: X-Request-Id: 7212c981-a838-4512-a9e2-4f98295bd3f7"
            },
            "expression": [
              "ValueSet.where(id = 'mii-vs-onko-strahlentherapie-strahlungseinheit')"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-strahlentherapie-zielgebiet",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-strahlentherapie-zielgebiet",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 433
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-strahlentherapie-zielgebiet: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7869
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-strahlentherapie-zielgebiet: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-studienteilnahme",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-studienteilnahme",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 422
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-studienteilnahme: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6673
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-studienteilnahme: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-systemische-therapie-art",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-systemische-therapie-art",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 430
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-art: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10753
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-art: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-systemische-therapie-ende-grund",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-systemische-therapie-ende-grund",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 437
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-ende-grund: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 9825
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-ende-grund: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-systemische-therapie-intention",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-systemische-therapie-intention",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 436
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-intention: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7970
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-intention: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-systemische-therapie-protokolle",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-systemische-therapie-protokolle",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 437
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-protokolle: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6895
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-protokolle: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-systemische-therapie-stellungzurop",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-systemische-therapie-stellungzurop",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 440
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-stellungzurop: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8587
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-stellungzurop: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-systemische-therapie-substanzen-2018",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-systemische-therapie-substanzen-2018",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 442
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 35509
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 35689
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA24' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AA24)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 35729
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA22' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AA22)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 35771
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L02BX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 35814
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01DB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 35856
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 35896
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XE13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 35938
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 35981
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX44' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX44)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[8]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36024
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L03AC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[9]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36065
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE36' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XE36)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[10]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36106
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AA15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[11]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36149
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA34' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AA34)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[12]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36194
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (M05BA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[13]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36238
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX22' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX22)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[14]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36280
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[15]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36320
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AM01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (V03AM01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[16]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36368
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L02BG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[17]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36417
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XD04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[18]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36458
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01DB10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[19]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36498
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[20]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36539
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX35' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX35)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[21]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36579
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[22]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36621
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L02BG03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[23]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36695
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[24]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36739
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX27' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX27)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[25]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36780
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'P01BE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (P01BE03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[26]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36824
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[27]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36868
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC32' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XC32)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[28]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36908
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC31' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XC31)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[29]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36948
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE17' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XE17)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[30]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36990
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01BC07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[31]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37033
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[32]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37076
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[33]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37121
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L03AX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[34]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37163
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA28' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AA28)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[35]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37204
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA26' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AA26)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[36]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37246
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX49' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX49)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[37]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37289
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01AA09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[38]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37332
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XC07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[39]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37373
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX25' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX25)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[40]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37416
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L02BB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[41]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37457
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01DC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[42]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37501
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC19' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XC19)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[43]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37543
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX32' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX32)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[44]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37584
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XE14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[45]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37635
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC12' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XC12)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[46]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37678
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AC09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[47]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37722
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N04BC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (N04BC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[48]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37763
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L02AE01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[49]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37803
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[50]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37846
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01CD04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[51]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37888
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N04BC06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (N04BC06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[52]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37932
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE26' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XE26)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[53]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37982
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (V03AF04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[54]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38023
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XC06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[55]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38066
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC24' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XC24)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[56]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38108
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC28' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XC28)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[57]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38161
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC26' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XC26)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[58]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38203
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XC11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[59]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38249
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (V03AF06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[60]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38292
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AC08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[61]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38335
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01BC06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[62]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38378
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[63]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38419
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01AC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[64]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38462
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX45' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX45)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[65]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38502
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01BC04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[66]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38543
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01AD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[67]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38584
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE28' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XE28)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[68]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38634
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[69]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38676
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (H01CC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[70]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38720
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01AA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[71]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38764
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03DB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (G03DB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[72]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38807
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01AA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[73]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38850
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[74]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38891
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[75]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38932
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01BB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[76]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38976
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (M05BA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[77]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39018
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01BB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[78]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39061
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE38' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XE38)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[79]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39103
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE16' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XE16)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[80]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39150
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01AA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[81]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39192
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03HA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (G03HA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[82]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39233
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01BC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[83]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39275
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE23' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XE23)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[84]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39317
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01AX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[85]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39359
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[86]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39403
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01DA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[87]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39451
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (B03XA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[88]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39492
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XE06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[89]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39536
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01DB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[90]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39577
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01BC08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[91]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39618
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L02BX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[92]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39660
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01CC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[93]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39710
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX29' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX29)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[94]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39751
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (M05BX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[95]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39795
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (H02AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[96]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39836
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01CD02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[97]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39879
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01DB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[98]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39921
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G04CB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (G04CB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[99]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39963
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA25' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AA25)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[100]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40005
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA21' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AA21)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[101]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40048
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XD06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[102]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40091
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B02BX05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (B02BX05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[103]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40134
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L02BB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[104]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40176
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01DB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[105]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40216
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX41' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX41)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[106]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40257
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XE03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[107]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40303
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (B03XA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[108]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40346
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[109]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40388
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[110]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40432
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (M05BA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[111]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40473
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01AG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[112]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40513
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01CB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[113]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40555
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XE10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[114]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40596
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L02BG06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[115]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40638
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L03AA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[116]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40680
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G04CB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (G04CB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[117]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40722
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA27' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AA27)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[118]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40764
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01BB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[119]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40808
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01BC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[120]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40867
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC52' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01BC52)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[121]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40907
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L02BB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[122]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40953
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (V03AF03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[123]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40994
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L02BG02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[124]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41036
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L02AA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[125]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41078
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01AD05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[126]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41121
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L02BA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[127]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41162
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XE02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[128]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41204
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01BC05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[129]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41246
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L02AB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[130]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41287
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[131]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41330
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (H01CA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[132]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41371
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L02AE03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[133]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41413
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA19' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AA19)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[134]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41467
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L03AX14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[135]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41508
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L02AE05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[136]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41555
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[137]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41600
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (M05BA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[138]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41656
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V10XX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (V10XX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[139]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41697
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE27' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XE27)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[140]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41739
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01DB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[141]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41781
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX47' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX47)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[142]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41822
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01AA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[143]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41862
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XE01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[144]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41903
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D06BB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (D06BB10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[145]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41945
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[146]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41991
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D06BX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (D06BX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[147]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42049
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L03AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[148]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42099
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L03AB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[149]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42149
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L03AB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[150]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42200
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L03AB18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[151]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42242
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX19' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX19)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[152]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42284
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01DC04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[153]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42324
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX50' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX50)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[154]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42365
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (H01CB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[155]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42406
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XE07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[156]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42448
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AA13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[157]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42491
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[158]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42534
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L03AA10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[159]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42576
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE29' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XE29)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[160]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42616
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L02BG04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[161]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42659
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L02AE02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[162]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42706
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L03AA14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[163]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42746
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01AD02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[164]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42787
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[165]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42830
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03DC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (G03DC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[166]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42873
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01AB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[167]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42914
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'J05AX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (J05AX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[168]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42956
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[169]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43006
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L02AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[170]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43047
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L02AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[171]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43088
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01AA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[172]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43131
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'R03DX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (R03DX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[173]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43176
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01BB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[174]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43213
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (V03AF01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[175]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43253
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N07BC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (N07BC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[176]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43296
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01BA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[177]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43339
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XD10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[178]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43409
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (B03XA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[179]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43461
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[180]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43510
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (H02AB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[181]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43553
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE39' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XE39)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[182]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43595
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L03AX15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[183]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43637
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[184]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43680
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CH01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01CH01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[185]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43723
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CP01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01CP01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[186]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43767
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01AX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[187]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43809
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX16' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX16)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[188]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43850
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01DC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[189]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43889
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX23' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX23)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[190]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43932
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01DB07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[191]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43976
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L03AA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[192]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44021
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[193]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44068
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[194]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44111
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA23' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AA23)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[195]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44161
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (V03AF10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[196]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44202
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01BB07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[197]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44243
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XE08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[198]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44284
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L02BB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[199]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44324
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01AD06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[200]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44366
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE31' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XE31)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[201]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44407
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC17' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XC17)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[202]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44451
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XC15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[203]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44493
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX36' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX36)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[204]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44534
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (H01CB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[205]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44574
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX46' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX46)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[206]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44616
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC27' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XC27)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[207]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44670
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX40' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX40)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[208]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44712
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L03AC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[209]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44755
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE35' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XE35)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[210]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44798
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[211]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44840
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01CD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[212]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44892
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01CD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[213]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44935
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE33' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XE33)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[214]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44977
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (V03AF08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[215]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45022
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (M05BA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[216]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45065
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XC08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[217]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45109
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX42' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX42)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[218]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45153
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX24' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX24)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[219]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45198
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L03AA13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[220]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45251
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L03AB11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[221]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45304
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L03AB10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[222]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45349
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XC18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[223]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45391
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01BA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[224]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45434
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[225]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XC13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[226]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45518
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01AX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[227]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45561
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01DB08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[228]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45602
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01DB11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[229]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45641
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AX10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (V03AX10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[230]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45683
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX16' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L03AX16)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[231]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45725
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01DC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[232]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45766
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L03AX08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[233]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45819
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L02AA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[234]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45864
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[235]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45907
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AX06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[236]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45948
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE24' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XE24)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[237]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45996
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[238]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46039
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01BA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[239]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46083
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D07AC18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (D07AC18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[240]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46127
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01AA08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[241]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46170
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (H02AB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[242]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46211
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (H02AB07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[243]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46254
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[244]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46317
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D05AD' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (D05AD)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[245]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46383
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D05BA' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (D05BA)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[246]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46424
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03XC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (G03XC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[247]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46467
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01BA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[248]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46510
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC21' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XC21)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[249]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46552
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01AD07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[250]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46595
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE21' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XE21)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[251]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46637
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE42' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XE42)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[252]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46679
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AC04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[253]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46724
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (M05BA07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[254]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46765
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[255]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46807
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX39' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX39)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[256]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46850
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B02BX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (B02BX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[257]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46893
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XE18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[258]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46936
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[259]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46976
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01AD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[260]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47018
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AC11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[261]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47059
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AA10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[262]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47103
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (H01CB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[263]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47144
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XE05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[264]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47188
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01AD04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[265]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47229
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XE04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[266]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47271
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AD02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[267]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47326
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX51' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX51)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[268]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47367
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L02BA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[269]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47409
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L03AX11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[270]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47463
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC53' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01BC53)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[271]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47513
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC63' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01BC63)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[272]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47576
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC73' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01BC73)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[273]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47618
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XD05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[274]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47661
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01AX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[275]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47705
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XE09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[276]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47746
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01CB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[277]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47788
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[278]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47828
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01AC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[279]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47870
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[280]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47915
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (M05BA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[281]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47956
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01BB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[282]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47997
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE34' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XE34)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[283]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48040
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AC07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[284]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48081
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX17' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX17)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[285]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48122
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L02BA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[286]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48186
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V10XA53' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (V10XA53)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[287]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48229
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01CX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[288]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48271
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE25' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XE25)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[289]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48314
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[290]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48366
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XC14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[291]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48408
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[292]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48449
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[293]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48491
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01AC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[294]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48549
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC59' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01BC59)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[295]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48592
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L02AE04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[296]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48635
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01AA07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[297]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48680
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N03AG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (N03AG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[298]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48722
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01DB09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[299]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48764
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE12' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XE12)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[300]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48807
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XE15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[301]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48849
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX52' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX52)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[302]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48891
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01CA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[303]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48933
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01CA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[304]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48973
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01CA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[305]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49014
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01CA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[306]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49056
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01CA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[307]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49098
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX43' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX43)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[308]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49141
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L04AD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[309]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49183
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX38' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX38)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[310]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49222
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L02BG05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[311]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49263
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX53' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01XX53)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[312]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49308
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (M05BA08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[313]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49349
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2018 (L01DB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2018: ValueSet.compose.include[0].concept[314]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-systemische-therapie-substanzen-2019",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-systemische-therapie-substanzen-2019",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 442
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36437
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36617
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA24' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AA24)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36657
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA22' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AA22)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36699
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L02BX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36742
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01DB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36784
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36824
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36866
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36909
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX44' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX44)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[8]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36952
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L03AC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[9]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36993
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE36' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE36)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[10]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37034
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AA15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[11]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37077
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA34' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AA34)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[12]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37122
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (M05BA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[13]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37166
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX22' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX22)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[14]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37208
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[15]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37248
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AM01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (V03AM01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[16]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37296
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L02BG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[17]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37345
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XD04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[18]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37386
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01DB10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[19]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37426
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[20]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37467
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX35' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX35)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[21]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37507
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[22]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37549
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L02BG03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[23]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37623
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[24]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37667
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX27' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX27)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[25]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37708
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'P01BE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (P01BE03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[26]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37752
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[27]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37796
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC32' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XC32)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[28]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37836
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC31' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XC31)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[29]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37876
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE17' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE17)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[30]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37918
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01BC07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[31]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 37961
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[32]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38004
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[33]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38049
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L03AX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[34]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38091
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA28' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AA28)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[35]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38132
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA26' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AA26)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[36]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38174
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX49' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX49)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[37]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38217
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01AA09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[38]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38260
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XC07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[39]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38301
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX25' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX25)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[40]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38344
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L02BB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[41]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38387
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE41' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE41)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[42]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38428
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01DC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[43]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38472
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC19' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XC19)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[44]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38514
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX32' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX32)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[45]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38555
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[46]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38606
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC12' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XC12)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[47]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38649
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AC09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[48]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38691
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE43' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE43)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[49]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38735
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N04BC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (N04BC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[50]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38776
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L02AE01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[51]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38816
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[52]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38859
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01CD04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[53]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38901
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N04BC06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (N04BC06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[54]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38945
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE26' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE26)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[55]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 38995
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (V03AF04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[56]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39038
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AC08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[57]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39081
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01BC06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[58]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39124
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[59]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39165
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01AC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[60]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39208
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX45' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX45)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[61]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39248
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01BC04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[62]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39289
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01AD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[63]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39330
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE28' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE28)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[64]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39380
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[65]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39422
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (H01CC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[66]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39463
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XC06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[67]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39507
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01AA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[68]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39551
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03DB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (G03DB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[69]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39594
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01AA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[70]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39637
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[71]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39678
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[72]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39719
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01BB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[73]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39763
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (M05BA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[74]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39805
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01BB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[75]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39848
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE38' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE38)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[76]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39890
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE16' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE16)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[77]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39937
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01AA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[78]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 39979
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03HA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (G03HA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[79]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40020
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01BC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[80]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40078
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XY01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XY01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[81]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40120
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE23' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE23)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[82]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40162
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01AX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[83]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40204
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[84]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40248
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01DA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[85]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40291
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC24' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XC24)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[86]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40339
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (B03XA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[87]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40380
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[88]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40424
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01DB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[89]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40465
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01BC08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[90]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40506
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L02BX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[91]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40548
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01CC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[92]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40598
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX29' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX29)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[93]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40639
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (M05BX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[94]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40683
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (H02AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[95]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40724
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01CD02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[96]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40767
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01DB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[97]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40809
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC28' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XC28)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[98]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40851
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G04CB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (G04CB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[99]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40893
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA25' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AA25)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[100]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40935
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA21' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AA21)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[101]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 40978
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XD06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[102]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41021
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B02BX05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (B02BX05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[103]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41063
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX59' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX59)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[104]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41106
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE46' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE46)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[105]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41149
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L02BB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[106]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41191
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01DB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[107]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41231
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX41' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX41)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[108]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41272
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[109]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41318
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (B03XA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[110]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41361
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[111]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41403
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[112]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41447
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (M05BA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[113]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41488
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01AG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[114]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41528
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01CB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[115]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41570
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[116]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41611
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L02BG06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[117]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41653
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L03AA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[118]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41695
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G04CB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (G04CB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[119]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41737
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA27' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AA27)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[120]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41779
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01BC09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[121]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41821
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01BB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[122]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41865
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01BC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[123]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41924
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC52' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01BC52)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[124]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 41964
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L02BB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[125]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42010
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (V03AF03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[126]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42051
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L02BG02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[127]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42093
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L02AA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[128]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42135
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01AD05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[129]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42178
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L02BA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[130]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42219
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[131]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42261
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01BC05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[132]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42303
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L02AB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[133]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42344
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[134]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42387
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (H01CA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[135]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42428
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L02AE03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[136]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42470
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA19' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AA19)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[137]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42524
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L03AX14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[138]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42565
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L02AE05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[139]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42612
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[140]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42657
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (M05BA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[141]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42713
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V10XX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (V10XX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[142]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42754
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE27' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE27)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[143]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42796
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01DB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[144]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42838
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX47' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX47)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[145]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42879
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01AA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[146]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42919
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[147]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 42960
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D06BB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (D06BB10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[148]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43002
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[149]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43048
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D06BX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (D06BX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[150]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43101
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC26' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XC26)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[151]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43159
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L03AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[152]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43209
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L03AB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[153]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43259
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L03AB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[154]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43310
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L03AB18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[155]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43352
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XC11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[156]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43394
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX19' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX19)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[157]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43436
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01DC04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[158]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX50' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX50)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[159]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43517
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (H01CB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[160]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43558
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[161]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43600
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AA13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[162]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43643
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[163]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43686
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L03AA10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[164]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43728
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE29' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE29)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[165]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43768
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L02BG04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[166]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43811
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L02AE02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[167]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43858
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L03AA14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[168]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43898
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01AD02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[169]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43939
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[170]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 43981
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE44' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE44)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[171]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44024
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03DC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (G03DC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[172]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44067
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01AB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[173]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44108
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'J05AX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (J05AX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[174]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44150
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[175]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44200
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L02AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[176]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44241
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L02AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[177]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44282
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01AA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[178]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44325
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'R03DX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (R03DX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[179]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44370
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01BB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[180]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44407
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (V03AF01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[181]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44447
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N07BC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (N07BC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[182]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44490
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01BA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[183]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44533
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XD10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[184]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44603
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (B03XA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[185]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44655
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[186]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44704
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (H02AB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[187]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44747
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE39' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE39)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[188]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44789
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L03AX15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[189]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44831
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[190]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44874
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CH01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01CH01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[191]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44917
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CP01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01CP01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[192]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 44961
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01AX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[193]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45003
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX16' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX16)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[194]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45044
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01DC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[195]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45083
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX23' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX23)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[196]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45126
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01DB07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[197]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45170
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L03AA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[198]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45215
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[199]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45262
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[200]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45305
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA23' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AA23)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[201]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45355
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (V03AF10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[202]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45396
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01BB07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[203]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45437
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE45' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE45)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[204]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45478
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[205]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45519
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L02BB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[206]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45559
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01AD06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[207]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45601
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE31' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE31)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[208]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45642
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX54' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX54)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[209]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45683
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC17' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XC17)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[210]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45727
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XC15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[211]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45769
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX36' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX36)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[212]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45810
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (H01CB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[213]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45850
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX46' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX46)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[214]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45892
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC27' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XC27)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[215]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45946
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX40' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX40)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[216]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 45988
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L03AC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[217]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46031
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE35' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE35)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[218]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46074
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[219]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46116
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01CD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[220]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46168
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01CD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[221]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46211
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE33' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE33)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[222]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46253
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (V03AF08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[223]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46298
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (M05BA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[224]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46341
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XC08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[225]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46385
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX42' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX42)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[226]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46429
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX24' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX24)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[227]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46474
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L03AA13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[228]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46527
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L03AB11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[229]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46580
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L03AB10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[230]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46625
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XC18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[231]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46667
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01BA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[232]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46710
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[233]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46752
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XC13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[234]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46794
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01AX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[235]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46837
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01DB08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[236]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46878
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01DB11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[237]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46917
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AX10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (V03AX10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[238]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 46959
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX16' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L03AX16)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[239]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47001
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01DC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[240]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47042
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L03AX08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[241]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47095
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L02AA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[242]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47140
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[243]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47183
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AX06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[244]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47224
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE24' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE24)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[245]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47272
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[246]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47315
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01BA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[247]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47359
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D07AC18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (D07AC18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[248]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47403
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01AA08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[249]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47446
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (H02AB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[250]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47487
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (H02AB07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[251]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47530
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[252]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47593
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D05AD' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (D05AD)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[253]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47659
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D05BA' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (D05BA)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[254]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47700
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03XC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (G03XC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[255]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47743
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01BA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[256]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47786
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC21' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XC21)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[257]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47828
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01AD07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[258]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47871
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE21' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE21)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[259]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47913
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE42' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE42)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[260]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47955
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AC04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[261]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48000
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (M05BA07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[262]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48041
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[263]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48083
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX39' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX39)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[264]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48126
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B02BX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (B02BX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[265]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48181
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L03AB15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[266]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48224
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[267]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48267
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[268]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48307
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01AD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[269]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48349
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AC11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[270]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48390
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AA10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[271]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48434
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (H01CB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[272]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48475
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[273]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48519
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01AD04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[274]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48560
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[275]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48602
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AD02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[276]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48657
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX51' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX51)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[277]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48698
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L02BA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[278]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48740
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L03AX11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[279]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48794
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC53' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01BC53)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[280]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48844
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC63' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01BC63)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[281]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48907
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC73' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01BC73)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[282]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48949
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XD05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[283]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48992
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01AX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[284]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49036
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[285]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49077
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01CB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[286]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49119
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[287]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49159
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01AC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[288]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49201
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[289]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49246
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (M05BA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[290]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49287
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01BB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[291]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49328
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE34' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE34)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[292]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49371
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AC07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[293]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49412
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX17' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX17)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[294]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49453
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L02BA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[295]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49517
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V10XA53' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (V10XA53)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[296]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49560
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01CX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[297]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49602
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE25' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE25)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[298]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49645
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[299]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49697
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XC14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[300]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49739
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[301]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49780
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[302]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49822
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01AC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[303]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49880
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC59' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01BC59)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[304]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49923
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L02AE04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[305]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49966
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01AA07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[306]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50007
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01AD08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[307]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50052
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N03AG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (N03AG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[308]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50094
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01DB09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[309]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50136
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE12' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE12)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[310]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50179
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XE15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[311]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50221
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX52' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX52)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[312]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50263
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01CA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[313]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50305
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01CA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[314]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50345
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01CA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[315]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50386
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01CA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[316]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50428
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01CA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[317]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50470
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX43' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX43)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[318]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50513
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L04AD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[319]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50555
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX38' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX38)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[320]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50594
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L02BG05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[321]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50635
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX53' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01XX53)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[322]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50680
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (M05BA08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[323]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50721
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2019 (L01DB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2019: ValueSet.compose.include[0].concept[324]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-systemische-therapie-substanzen-2020",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-systemische-therapie-substanzen-2020",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 442
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48881
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49061
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA24' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AA24)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49104
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE50' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE50)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49144
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA22' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AA22)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49186
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L02BX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49231
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE51' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE51)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49274
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01DB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49316
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49356
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[8]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49398
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[9]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49441
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX44' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX44)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[10]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49484
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L03AC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[11]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49525
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE36' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE36)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[12]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49566
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AA15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[13]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49609
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA34' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AA34)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[14]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49654
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (M05BA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[15]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49698
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX22' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX22)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[16]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49740
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[17]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49780
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AM01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (V03AM01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[18]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49828
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L02BG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[19]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49877
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XD04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[20]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49918
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01DB10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[21]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49958
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[22]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49999
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX35' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX35)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[23]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50039
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[24]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50081
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L02BG03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[25]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50155
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[26]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50197
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L02BB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[27]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50241
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX27' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX27)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[28]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50282
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'P01BE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (P01BE03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[29]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50326
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[30]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50370
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC32' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XC32)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[31]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50410
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC31' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XC31)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[32]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50450
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE17' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE17)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[33]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50492
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01BC07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[34]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50535
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[35]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50578
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[36]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50623
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L03AX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[37]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50665
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA28' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AA28)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[38]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50706
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA26' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AA26)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[39]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50748
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX49' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX49)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[40]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50791
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01AA09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[41]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50834
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XC07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[42]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50875
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX25' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX25)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[43]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50918
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L02BB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[44]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50961
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE41' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE41)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[45]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51002
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01DC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[46]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51046
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC19' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XC19)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[47]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51088
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX32' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX32)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[48]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51129
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[49]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51180
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC12' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XC12)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[50]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51223
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AC09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[51]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51265
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE43' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE43)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[52]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51309
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N04BC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (N04BC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[53]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51350
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L02AE01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[54]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51390
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[55]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51433
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01CD04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[56]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51475
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N04BC06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (N04BC06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[57]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51519
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE26' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE26)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[58]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51569
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (V03AF04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[59]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51612
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AC08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[60]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51655
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01BC06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[61]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51698
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[62]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51739
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01AC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[63]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51782
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX45' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX45)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[64]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51822
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01BC04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[65]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51863
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01AD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[66]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51904
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE28' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE28)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[67]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51954
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[68]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51996
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (H01CC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[69]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52037
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XC06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[70]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52081
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01AA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[71]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52125
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03DB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (G03DB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[72]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52168
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01AA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[73]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52211
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[74]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52252
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[75]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52293
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01BB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[76]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52337
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (M05BA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[77]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52379
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01BB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[78]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52422
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE38' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE38)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[79]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52464
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX61' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX61)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[80]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52506
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE16' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE16)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[81]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52553
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01AA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[82]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52595
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03HA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (G03HA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[83]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52636
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01BC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[84]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52694
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XY01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XY01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[85]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52736
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE23' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE23)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[86]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52778
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01AX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[87]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52820
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[88]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52864
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01DA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[89]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52907
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC24' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XC24)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[90]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52955
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (B03XA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[91]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52998
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L02BB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[92]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53039
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[93]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53083
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01DB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[94]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53124
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01BC08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[95]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53165
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L02BX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[96]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53207
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01CC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[97]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53257
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX29' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX29)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[98]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53298
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (M05BX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[99]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53342
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (H02AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[100]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53383
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01CD02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[101]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53426
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01DB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[102]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53468
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC28' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XC28)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[103]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53510
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G04CB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (G04CB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[104]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53552
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA25' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AA25)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[105]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53594
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA21' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AA21)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[106]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53637
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XD06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[107]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53680
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B02BX05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (B02BX05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[108]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53722
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX59' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX59)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[109]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53765
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE46' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE46)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[110]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53808
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L02BB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[111]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53850
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01DB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[112]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53890
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX41' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX41)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[113]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53931
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[114]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53977
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (B03XA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[115]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54020
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[116]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54062
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[117]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54106
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (M05BA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[118]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54147
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01AG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[119]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54187
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01CB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[120]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54229
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[121]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54270
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L02BG06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[122]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54312
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L03AA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[123]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54354
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G04CB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (G04CB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[124]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54396
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA27' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AA27)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[125]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54438
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01BC09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[126]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54480
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01BB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[127]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54524
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01BC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[128]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54583
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC52' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01BC52)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[129]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54623
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L02BB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[130]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54669
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (V03AF03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[131]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54710
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L02BG02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[132]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54752
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L02AA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[133]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54796
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B02BX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (B02BX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[134]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54838
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01AD05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[135]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54881
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L02BA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[136]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54922
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[137]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54964
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01BC05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[138]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55006
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L02AB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[139]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55050
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE54' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE54)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[140]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55091
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX63' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX63)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[141]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55132
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[142]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55175
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (H01CA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[143]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55216
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L02AE03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[144]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55258
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA19' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AA19)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[145]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55312
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L03AX14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[146]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55353
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L02AE05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[147]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55400
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[148]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55445
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (M05BA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[149]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55501
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V10XX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (V10XX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[150]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55542
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE27' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE27)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[151]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55584
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01DB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[152]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55626
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX47' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX47)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[153]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55667
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01AA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[154]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55707
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[155]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55748
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D06BB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (D06BB10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[156]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55790
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[157]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55836
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D06BX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (D06BX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[158]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55889
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC26' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XC26)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[159]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55947
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L03AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[160]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55997
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L03AB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[161]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56047
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L03AB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[162]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56098
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L03AB18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[163]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56140
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XC11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[164]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56182
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX19' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX19)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[165]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56224
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX62' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX62)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[166]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56266
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01DC04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[167]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56306
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX50' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX50)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[168]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56347
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (H01CB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[169]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56388
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[170]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56433
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE53' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE53)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[171]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56475
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AA13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[172]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56518
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[173]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56561
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L03AA10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[174]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56603
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE29' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE29)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[175]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56643
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L02BG04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[176]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56686
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L02AE02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[177]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56733
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L03AA14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[178]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56773
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01AD02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[179]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56814
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[180]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56856
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE44' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE44)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[181]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56900
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (B03XA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[182]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56943
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03DC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (G03DC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[183]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56986
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01AB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[184]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57027
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'J05AX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (J05AX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[185]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57069
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[186]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57119
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L02AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[187]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57160
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L02AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[188]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57201
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01AA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[189]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57244
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'R03DX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (R03DX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[190]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57289
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01BB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[191]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57326
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (V03AF01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[192]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57366
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N07BC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (N07BC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[193]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57409
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01BA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[194]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57452
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XD10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[195]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57522
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (B03XA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[196]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57574
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[197]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57623
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (H02AB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[198]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57666
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE39' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE39)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[199]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57708
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L03AX15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[200]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57750
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[201]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57793
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CH01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01CH01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[202]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57836
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CP01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01CP01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[203]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57880
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01AX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[204]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57922
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX16' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX16)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[205]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57963
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01DC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[206]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58002
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX23' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX23)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[207]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58045
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01DB07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[208]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58089
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L03AA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[209]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58134
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[210]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58181
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[211]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58224
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA23' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AA23)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[212]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58274
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (V03AF10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[213]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58315
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01BB07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[214]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58356
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE45' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE45)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[215]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58397
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[216]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58438
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L02BB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[217]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58478
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01AD06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[218]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58520
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE31' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE31)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[219]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58561
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX54' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX54)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[220]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58602
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC17' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XC17)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[221]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58646
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XC15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[222]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58688
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX36' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX36)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[223]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58729
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (H01CB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[224]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58769
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX46' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX46)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[225]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58811
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC27' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XC27)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[226]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58865
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX40' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX40)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[227]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58907
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L03AC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[228]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58950
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE35' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE35)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[229]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58993
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[230]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59035
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01CD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[231]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59087
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01CD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[232]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59130
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE33' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE33)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[233]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59172
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (V03AF08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[234]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59217
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (M05BA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[235]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59260
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XC08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[236]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59304
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX42' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX42)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[237]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59348
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX24' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX24)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[238]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59393
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L03AA13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[239]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59446
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L03AB11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[240]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59499
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L03AB10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[241]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59544
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XC18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[242]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59586
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01BA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[243]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59629
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[244]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59671
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XC13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[245]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59713
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01AX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[246]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59756
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01DB08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[247]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59797
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01DB11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[248]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59836
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AX10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (V03AX10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[249]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59878
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX16' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L03AX16)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[250]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59920
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01DC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[251]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59961
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L03AX08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[252]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60014
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L02AA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[253]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60059
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[254]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60102
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AX06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[255]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60143
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE24' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE24)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[256]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60191
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[257]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60234
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01BA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[258]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60278
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D07AC18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (D07AC18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[259]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60322
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01AA08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[260]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60365
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (H02AB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[261]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60406
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (H02AB07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[262]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60449
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[263]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60512
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D05AD' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (D05AD)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[264]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60578
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D05BA' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (D05BA)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[265]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60621
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE52' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE52)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[266]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60662
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03XC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (G03XC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[267]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60705
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01BA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[268]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60748
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC21' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XC21)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[269]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60790
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01AD07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[270]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60833
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE21' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE21)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[271]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60875
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE42' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE42)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[272]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60917
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AC04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[273]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60962
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (M05BA07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[274]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61003
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[275]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61045
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX39' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX39)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[276]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61088
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B02BX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (B02BX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[277]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61143
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L03AB15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[278]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61186
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[279]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61229
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[280]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61269
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01AD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[281]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61311
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AC11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[282]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61352
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AA10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[283]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61396
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (H01CB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[284]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61437
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[285]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61481
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01AD04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[286]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61522
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[287]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61564
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AD02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[288]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61607
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX60' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX60)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[289]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61662
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX51' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX51)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[290]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61703
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L02BA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[291]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61745
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L03AX11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[292]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61799
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC53' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01BC53)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[293]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61849
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC63' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01BC63)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[294]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61912
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC73' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01BC73)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[295]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61954
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XD05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[296]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61997
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01AX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[297]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62041
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[298]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62082
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01CB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[299]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62124
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[300]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62164
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01AC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[301]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62206
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[302]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62251
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (M05BA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[303]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62292
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01BB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[304]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62333
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE34' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE34)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[305]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62376
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AC07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[306]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62417
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX17' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX17)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[307]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62458
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L02BA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[308]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62522
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V10XA53' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (V10XA53)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[309]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62565
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01CX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[310]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62607
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE25' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE25)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[311]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62650
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[312]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62702
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XC14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[313]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62744
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[314]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62785
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[315]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62827
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01AC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[316]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62885
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC59' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01BC59)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[317]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62928
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L02AE04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[318]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62971
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01AA07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[319]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63012
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01AD08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[320]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63057
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N03AG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (N03AG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[321]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63099
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01DB09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[322]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63141
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE12' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE12)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[323]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63184
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XE15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[324]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63226
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX52' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX52)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[325]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63268
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01CA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[326]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63310
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01CA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[327]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63350
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01CA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[328]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63391
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01CA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[329]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63433
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01CA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[330]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63475
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX43' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX43)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[331]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63518
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L04AD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[332]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63560
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX38' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX38)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[333]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63599
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L02BG05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[334]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63640
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX53' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01XX53)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[335]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63685
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (M05BA08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[336]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63726
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2020 (L01DB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2020: ValueSet.compose.include[0].concept[337]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-systemische-therapie-substanzen-2021",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-systemische-therapie-substanzen-2021",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 442
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47237
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47417
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA24' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AA24)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47460
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EF03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EF03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47500
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA22' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AA22)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47542
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L02BX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47587
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EL02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EL02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47630
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01DB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47672
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47712
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[8]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47754
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[9]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47797
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX44' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XX44)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[10]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47840
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L03AC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[11]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47881
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01ED03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[12]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47922
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AA15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[13]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47965
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA34' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AA34)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[14]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48010
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (M05BA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[15]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48054
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XF02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XF02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[16]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48095
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EM03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EM03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[17]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48137
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[18]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48177
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AM01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (V03AM01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[19]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48225
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L02BG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[20]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48274
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XD04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[21]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48315
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01DB10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[22]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48355
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[23]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48396
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX35' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XX35)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[24]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48436
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[25]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48478
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L02BG03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[26]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48552
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[27]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48594
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L02BB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[28]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48638
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX27' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XX27)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[29]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48679
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'P01BE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (P01BE03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[30]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48723
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[31]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48767
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC32' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XC32)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[32]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48810
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EX18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[33]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48850
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC31' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XC31)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[34]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48904
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX70' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XX70)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[35]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48944
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EK01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EK01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[36]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48986
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01BC07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[37]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49029
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[38]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49072
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[39]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49117
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L03AX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[40]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49159
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA28' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AA28)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[41]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49200
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA26' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AA26)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[42]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49242
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XH04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XH04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[43]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49285
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01AA09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[44]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49328
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XC07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[45]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49369
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XF03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XF03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[46]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49412
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L02BB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[47]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49455
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EE03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[48]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49496
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01DC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[49]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49540
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC19' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XC19)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[50]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49582
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[51]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49623
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[52]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49674
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC12' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XC12)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[53]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49717
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AC09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[54]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49759
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01ED04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[55]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49803
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N04BC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (N04BC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[56]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49844
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L02AE01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[57]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49884
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[58]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49927
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01CD04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[59]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49969
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N04BC06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (N04BC06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[60]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50013
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EX07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[61]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50063
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (V03AF04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[62]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50106
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AC08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[63]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50149
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01BC06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[64]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50191
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX17' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EX17)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[65]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50234
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[66]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50275
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01AC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[67]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50318
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XG02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XG02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[68]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50358
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01BC04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[69]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50399
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01AD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[70]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50440
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01ED02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[71]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50490
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[72]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50532
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (H01CC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[73]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50573
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XC06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[74]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50617
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01AA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[75]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50661
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03DB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (G03DB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[76]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50704
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01AA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[77]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50747
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[78]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50788
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[79]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50829
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01BB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[80]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50873
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (M05BA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[81]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50915
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01BB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[82]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50958
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EE02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[83]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51000
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EM02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EM02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[84]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51042
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01ED01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[85]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51089
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01AA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[86]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51131
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03HA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (G03HA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[87]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51172
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01BC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[88]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51230
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XY01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XY01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[89]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51272
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[90]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51314
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01AX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[91]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51356
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[92]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51399
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EB07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[93]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51443
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01DA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[94]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51486
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC24' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XC24)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[95]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51534
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (B03XA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[96]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51577
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L02BB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[97]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51618
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[98]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51662
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01DB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[99]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51703
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01BC08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[100]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51744
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L02BX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[101]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51786
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01CC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[102]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51836
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX29' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XX29)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[103]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51877
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (M05BX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[104]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51921
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (H02AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[105]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51962
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01CD02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[106]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52005
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01DB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[107]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52047
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC28' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XC28)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[108]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52089
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G04CB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (G04CB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[109]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52130
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EM04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EM04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[110]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52172
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA25' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AA25)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[111]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52214
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA21' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AA21)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[112]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52257
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XD06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[113]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52300
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B02BX05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (B02BX05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[114]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52342
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX59' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XX59)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[115]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52385
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[116]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52428
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EX14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[117]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52471
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L02BB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[118]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52513
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01DB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[119]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52553
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX41' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XX41)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[120]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52594
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[121]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52640
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (B03XA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[122]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52683
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XX11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[123]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52725
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[124]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52769
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (M05BA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[125]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52810
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01AG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[126]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52850
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01CB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[127]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52892
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EG02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EG02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[128]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52933
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L02BG06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[129]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52975
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EJ02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EJ02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[130]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53017
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L03AA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[131]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53059
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G04CB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (G04CB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[132]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53101
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA27' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AA27)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[133]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53143
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01BC09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[134]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53185
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01BB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[135]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53229
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01BC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[136]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53288
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC52' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01BC52)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[137]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53328
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L02BB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[138]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53374
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (V03AF03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[139]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53415
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L02BG02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[140]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53457
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L02AA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[141]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53501
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B02BX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (B02BX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[142]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53543
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01AD05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[143]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53586
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L02BA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[144]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53627
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[145]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53669
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01BC05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[146]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53711
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L02AB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[147]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53755
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EX13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[148]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53796
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XJ03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XJ03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[149]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53837
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[150]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53880
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (H01CA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[151]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53921
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L02AE03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[152]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53963
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA19' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AA19)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[153]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54017
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L03AX14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[154]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54058
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L02AE05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[155]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54105
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XX05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[156]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54150
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (M05BA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[157]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54206
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V10XX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (V10XX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[158]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54247
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EL01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EL01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[159]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54289
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01DB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[160]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54331
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EM01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EM01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[161]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54372
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01AA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[162]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54412
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[163]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54453
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D06BB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (D06BB10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[164]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54495
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[165]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54541
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D06BX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (D06BX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[166]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54594
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC26' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XC26)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[167]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54652
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L03AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[168]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54702
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L03AB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[169]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54752
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L03AB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[170]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54803
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L03AB18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[171]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54845
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XC11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[172]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54887
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CE02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01CE02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[173]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54929
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX62' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XX62)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[174]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54971
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01DC04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[175]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55011
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XG03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XG03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[176]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55054
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02CA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (H02CA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[177]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55095
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (H01CB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[178]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55136
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EH01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EH01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[179]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55181
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX12' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EX12)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[180]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55223
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AA13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[181]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55266
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[182]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55309
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L03AA10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[183]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55351
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EX08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[184]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55391
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L02BG04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[185]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55434
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L02AE02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[186]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55481
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L03AA14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[187]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55521
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01AD02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[188]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55562
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XX07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[189]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55604
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01ED05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[190]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55648
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (B03XA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[191]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55691
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03DC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (G03DC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[192]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55734
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01AB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[193]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55775
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'J05AX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (J05AX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[194]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55817
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XX10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[195]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55867
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L02AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[196]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55908
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L02AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[197]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55949
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01AA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[198]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55992
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'R03DX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (R03DX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[199]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56037
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01BB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[200]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56074
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (V03AF01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[201]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56114
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N07BC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (N07BC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[202]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56157
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01BA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[203]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56200
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XD10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[204]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56270
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (B03XA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[205]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56322
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[206]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56371
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (H02AB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[207]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56414
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EX10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[208]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56456
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L03AX15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[209]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56498
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[210]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56541
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CH01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01CH01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[211]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56584
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CP01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01CP01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[212]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56628
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01AX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[213]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56670
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX16' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XX16)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[214]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56711
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01DC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[215]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56750
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX23' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XX23)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[216]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56793
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01DB07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[217]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56837
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L03AA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[218]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56882
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[219]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56929
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[220]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56972
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA23' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AA23)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[221]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57022
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (V03AF10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[222]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57063
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01BB07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[223]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57104
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EH02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EH02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[224]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57145
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[225]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57186
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L02BB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[226]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57226
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01AD06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[227]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57268
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[228]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57309
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XK02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[229]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57350
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC17' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XC17)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[230]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57394
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XC15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[231]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57436
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX36' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XX36)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[232]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57477
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (H01CB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[233]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57517
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XK01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[234]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57559
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC27' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XC27)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[235]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57613
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX40' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XX40)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[236]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57655
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L03AC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[237]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57698
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[238]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57741
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[239]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57783
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01CD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[240]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57835
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01CD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[241]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57878
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EF01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EF01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[242]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57920
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (V03AF08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[243]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57965
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (M05BA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[244]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58008
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XC08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[245]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58052
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XH03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XH03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[246]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58093
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[247]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58137
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX24' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XX24)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[248]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58182
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L03AA13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[249]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58235
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L03AB11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[250]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58288
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L03AB10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[251]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58333
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XC18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[252]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58375
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01BA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[253]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58418
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XX08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[254]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58460
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XC13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[255]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58502
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01AX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[256]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58545
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01DB08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[257]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58586
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01DB11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[258]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58625
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AX10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (V03AX10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[259]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58667
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX16' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L03AX16)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[260]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58709
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01DC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[261]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58750
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L03AX08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[262]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58803
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L02AA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[263]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58848
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[264]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58891
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AX06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[265]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58932
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[266]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58980
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[267]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59023
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01BA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[268]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59067
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D07AC18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (D07AC18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[269]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59111
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01AA08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[270]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59154
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (H02AB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[271]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59195
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (H02AB07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[272]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59238
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[273]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59301
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D05AD' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (D05AD)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[274]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59367
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D05BA' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (D05BA)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[275]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59410
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EX11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[276]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59451
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03XC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (G03XC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[277]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59494
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01BA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[278]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59537
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC21' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XC21)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[279]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59579
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01AD07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[280]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59622
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EX05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[281]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59664
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EF02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EF02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[282]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59706
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AC04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[283]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59748
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX19' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EX19)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[284]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59793
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (M05BA07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[285]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59834
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[286]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59876
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XH02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XH02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[287]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59919
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B02BX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (B02BX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[288]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59974
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L03AB15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[289]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60015
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XK03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[290]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60058
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EJ01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EJ01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[291]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60101
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[292]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60142
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX66' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XX66)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[293]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60185
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EE04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[294]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60225
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01AD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[295]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60267
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AC11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[296]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60308
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AA10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[297]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60352
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (H01CB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[298]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60393
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XJ02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XJ02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[299]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60434
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[300]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60478
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01AD04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[301]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60519
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[302]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60561
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AD02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[303]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60604
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX67' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XX67)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[304]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60647
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XK04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[305]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60702
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX51' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XX51)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[306]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60743
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L02BA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[307]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60785
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L03AX11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[308]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60839
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC53' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01BC53)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[309]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60889
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC63' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01BC63)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[310]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60952
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC73' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01BC73)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[311]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60994
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XD05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[312]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61037
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01AX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[313]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61081
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[314]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61122
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01CB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[315]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61163
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX21' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EX21)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[316]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61205
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[317]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61245
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01AC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[318]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61287
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XX18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[319]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61332
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (M05BA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[320]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61373
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01BB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[321]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61421
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX71' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XX71)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[322]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61462
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EK03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EK03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[323]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61505
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AC07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[324]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61546
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01CE01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[325]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61587
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L02BA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[326]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61651
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V10XA53' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (V10XA53)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[327]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61694
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01CX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[328]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61736
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EE01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[329]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61779
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[330]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61831
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XC14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XC14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[331]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61873
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[332]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61914
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XF01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XF01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[333]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61956
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01AC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[334]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62014
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC59' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01BC59)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[335]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62057
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L02AE04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[336]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62100
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01AA07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[337]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62141
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EH03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EH03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[338]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62182
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01AD08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[339]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62227
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N03AG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (N03AG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[340]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62269
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01DB09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[341]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62311
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[342]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62352
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XK05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[343]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62395
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[344]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62437
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX52' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XX52)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[345]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62479
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01CA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[346]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62521
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01CA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[347]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62561
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01CA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[348]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62602
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01CA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[349]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62644
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01CA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[350]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62686
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XJ01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XJ01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[351]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62729
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L04AD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[352]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62771
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XH01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XH01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[353]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62810
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L02BG05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[354]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62851
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX53' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01XX53)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[355]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62895
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EL03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01EL03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[356]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62940
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (M05BA08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[357]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62981
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2021 (L01DB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2021: ValueSet.compose.include[0].concept[358]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-systemische-therapie-substanzen-2022",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-systemische-therapie-substanzen-2022",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 442
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47533
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47713
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA24' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AA24)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47756
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EF03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EF03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47796
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA22' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AA22)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47838
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L02BX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47883
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EL02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EL02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47926
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01DB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47968
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48008
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[8]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48050
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[9]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48093
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX44' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XX44)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[10]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48136
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L03AC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[11]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48177
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01ED03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[12]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48218
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AA15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[13]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48261
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA34' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AA34)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[14]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48306
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (M05BA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[15]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48350
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XF02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XF02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[16]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48391
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EM03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EM03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[17]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48433
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[18]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48473
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AM01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (V03AM01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[19]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48521
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L02BG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[20]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48570
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XD04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[21]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48613
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FX18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[22]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48654
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01DB10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[23]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48694
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[24]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48735
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX35' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XX35)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[25]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48775
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[26]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48817
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L02BG03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[27]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48891
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[28]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48933
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L02BB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[29]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48977
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX27' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XX27)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[30]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49018
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'P01BE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (P01BE03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[31]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49059
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[32]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49103
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[33]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49147
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FF05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[34]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49190
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EX18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[35]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49230
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FF04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[36]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49284
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX70' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XX70)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[37]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49324
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EK01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EK01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[38]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49366
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01BC07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[39]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49409
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[40]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49452
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[41]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49497
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L03AX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[42]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49549
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FX15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[43]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49591
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA28' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AA28)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[44]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49632
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA26' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AA26)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[45]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49674
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XH04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XH04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[46]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49717
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01AA09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[47]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49760
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[48]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49801
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XF03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XF03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[49]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49844
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L02BB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[50]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49887
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EE03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[51]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49928
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01DC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[52]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49972
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FX07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[53]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50014
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[54]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50055
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[55]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50106
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FX05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[56]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50149
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AC09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[57]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50191
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01ED04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[58]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50235
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N04BC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (N04BC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[59]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50276
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L02AE01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[60]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50316
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[61]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50359
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01CD04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[62]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50401
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N04BC06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (N04BC06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[63]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50445
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EX07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[64]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50495
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (V03AF04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[65]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50538
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AC08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[66]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50581
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01BC06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[67]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50623
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX17' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EX17)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[68]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50666
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[69]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50707
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01AC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[70]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50750
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XG02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XG02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[71]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50790
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01BC04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[72]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50831
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01AD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[73]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50874
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[74]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50916
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FF06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[75]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50957
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01ED02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[76]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51007
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[77]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51049
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (H01CC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[78]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51090
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FE01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[79]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51134
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01AA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[80]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51178
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03DB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (G03DB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[81]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51221
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01AA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[82]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51264
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[83]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51305
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[84]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51346
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01BB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[85]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51390
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (M05BA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[86]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51432
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01BB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[87]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51475
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EE02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[88]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51517
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EM02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EM02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[89]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51559
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01ED01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[90]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51606
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01AA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[91]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51648
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03HA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (G03HA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[92]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51689
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01BC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[93]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51747
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XY01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XY01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[94]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51789
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[95]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51831
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01AX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[96]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51873
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[97]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51916
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EB07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[98]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51960
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01DA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[99]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52003
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[100]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52051
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (B03XA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[101]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52094
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L02BB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[102]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52135
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[103]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52179
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01DB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[104]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52220
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01BC08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[105]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52261
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L02BX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[106]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52303
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01CC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[107]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52353
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX29' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XX29)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[108]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52394
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (M05BX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[109]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52438
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (H02AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[110]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52486
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FX06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[111]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52527
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01CD02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[112]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52570
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FF07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[113]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52613
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01DB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[114]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52655
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FF03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[115]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52697
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G04CB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (G04CB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[116]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52738
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EM04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EM04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[117]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52780
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA25' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AA25)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[118]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52823
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[119]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52865
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA21' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AA21)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[120]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52908
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XD06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[121]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52950
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FX08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[122]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52993
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B02BX05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (B02BX05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[123]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53035
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX59' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XX59)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[124]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53078
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[125]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53128
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FX13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[126]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53171
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EX14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[127]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53214
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L02BB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[128]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53256
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01DB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[129]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53299
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EN01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EN01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[130]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53339
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX41' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XX41)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[131]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53380
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[132]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53426
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (B03XA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[133]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53469
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XX11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[134]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53511
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[135]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53555
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (M05BA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[136]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53596
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01AG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[137]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53636
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01CB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[138]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53678
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EG02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EG02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[139]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53719
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L02BG06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[140]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53761
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EJ02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EJ02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[141]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53803
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L03AA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[142]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53845
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G04CB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (G04CB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[143]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53887
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA27' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AA27)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[144]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53929
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01BC09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[145]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53971
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01BB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[146]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54015
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01BC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[147]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54074
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC52' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01BC52)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[148]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54114
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L02BB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[149]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54160
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (V03AF03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[150]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54201
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L02BG02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[151]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54243
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L02AA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[152]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54287
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B02BX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (B02BX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[153]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54329
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01AD05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[154]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54372
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L02BA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[155]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54415
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EN04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EN04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[156]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54456
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[157]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54498
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01BC05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[158]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54551
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[159]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54593
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L02AB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[160]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54637
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EX13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[161]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54678
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XJ03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XJ03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[162]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54719
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[163]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54762
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (H01CA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[164]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54803
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L02AE03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[165]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54845
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA19' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AA19)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[166]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54899
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L03AX14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[167]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54940
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L02AE05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[168]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54987
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XX05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[169]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55032
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (M05BA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[170]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55088
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V10XX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (V10XX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[171]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55129
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EL01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EL01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[172]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55171
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01DB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[173]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55213
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EM01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EM01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[174]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55254
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01AA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[175]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55294
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[176]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55335
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D06BB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (D06BB10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[177]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55377
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[178]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55423
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D06BX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (D06BX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[179]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[180]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55534
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L03AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[181]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55584
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L03AB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[182]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55634
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L03AB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[183]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55685
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L03AB18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[184]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55727
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[185]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55769
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CE02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01CE02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[186]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55811
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[187]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55853
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX62' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XX62)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[188]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55895
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01DC04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[189]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55935
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XG03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XG03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[190]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55978
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02CA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (H02CA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[191]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56019
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (H01CB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[192]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56060
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EH01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EH01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[193]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56105
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX12' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EX12)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[194]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56147
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AA13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[195]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56190
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[196]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56233
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L03AA10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[197]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56275
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EX08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[198]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56315
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L02BG04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[199]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56358
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L02AE02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[200]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56405
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L03AA14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[201]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56445
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01AD02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[202]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56487
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'A16AX20' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (A16AX20)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[203]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56528
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XX07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[204]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56570
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01ED05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[205]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56615
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX69' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XX69)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[206]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56659
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (B03XA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[207]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56702
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03DC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (G03DC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[208]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56745
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01AB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[209]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56786
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'J05AX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (J05AX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[210]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56828
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XX10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[211]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56878
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L02AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[212]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56919
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L02AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[213]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56960
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01AA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[214]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57003
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'R03DX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (R03DX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[215]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57048
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01BB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[216]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57085
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (V03AF01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[217]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57125
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N07BC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (N07BC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[218]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57168
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01BA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[219]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57211
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XD10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[220]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57281
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (B03XA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[221]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57333
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[222]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57382
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (H02AB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[223]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57425
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EX10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[224]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57467
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L03AX15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[225]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57509
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[226]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57552
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CH01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01CH01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[227]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57595
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CP01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01CP01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[228]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57639
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01AX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[229]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57681
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX16' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XX16)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[230]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57722
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01DC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[231]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57761
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX23' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XX23)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[232]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57804
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01DB07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[233]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57849
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[234]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57893
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L03AA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[235]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57946
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[236]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57991
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[237]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58038
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[238]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58081
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA23' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AA23)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[239]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58131
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (V03AF10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[240]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58174
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FE03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[241]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58215
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01BB07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[242]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58256
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EH02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EH02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[243]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58297
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[244]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58338
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L02BB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[245]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58378
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01AD06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[246]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58420
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[247]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58461
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XK02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[248]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58502
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FF01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[249]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58546
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[250]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58588
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX36' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XX36)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[251]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58629
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (H01CB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[252]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58671
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[253]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58711
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XK01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[254]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58753
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FX10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[255]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58807
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX40' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XX40)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[256]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58858
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX16' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FX16)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[257]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58900
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L03AC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[258]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58943
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[259]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58986
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[260]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59028
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01CD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[261]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59080
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01CD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[262]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59123
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EF01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EF01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[263]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59165
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (V03AF08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[264]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59210
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (M05BA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[265]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59253
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FE02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FE02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[266]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59297
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XH03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XH03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[267]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59338
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[268]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59382
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX24' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XX24)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[269]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59427
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L03AA13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[270]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59480
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L03AB11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[271]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59533
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L03AB10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[272]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59578
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FF02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[273]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59620
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01BA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[274]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59663
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EN02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EN02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[275]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59706
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XX08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[276]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59748
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FD02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[277]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59806
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XY02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XY02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[278]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59848
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01AX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[279]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59891
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01DB08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[280]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59932
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01DB11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[281]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59971
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AX10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (V03AX10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[282]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60013
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX16' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L03AX16)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[283]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60055
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01DC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[284]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60106
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FX14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[285]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60147
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L03AX08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[286]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60200
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L02AA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[287]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60245
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[288]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60288
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AX06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[289]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60329
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[290]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60377
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[291]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60420
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01BA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[292]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60463
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX23' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EX23)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[293]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60507
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D07AC18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (D07AC18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[294]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60551
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01AA08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[295]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60594
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (H02AB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[296]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60635
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (H02AB07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[297]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60678
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[298]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60741
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D05AD' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (D05AD)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[299]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60807
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D05BA' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (D05BA)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[300]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60850
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EX11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[301]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60891
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03XC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (G03XC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[302]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60934
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01BA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[303]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60977
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FG02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FG02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[304]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61019
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01AD07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[305]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61062
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EX05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[306]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61106
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FF10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[307]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61148
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EF02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EF02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[308]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61190
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AC04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[309]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61232
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX19' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EX19)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[310]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61277
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (M05BA07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[311]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61318
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[312]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61360
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XH02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XH02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[313]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61403
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B02BX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (B02BX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[314]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61458
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L03AB15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[315]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61499
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XK03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[316]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61542
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EJ01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EJ01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[317]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61595
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX17' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FX17)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[318]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61638
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[319]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61679
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX66' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XX66)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[320]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61724
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX22' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EX22)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[321]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61767
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EE04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[322]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61807
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01AD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[323]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61849
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AC11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[324]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61890
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AA10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[325]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61934
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (H01CB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[326]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61975
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XJ02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XJ02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[327]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62016
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[328]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62057
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX73' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XX73)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[329]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62101
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01AD04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[330]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62142
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[331]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62184
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AD02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[332]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62227
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX12' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FX12)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[333]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62270
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX67' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XX67)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[334]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62313
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XK04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[335]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62368
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX51' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XX51)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[336]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62409
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L02BA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[337]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62451
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L03AX11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[338]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62495
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX72' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XX72)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[339]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62549
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC53' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01BC53)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[340]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62599
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC63' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01BC63)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[341]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62662
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC73' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01BC73)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[342]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62704
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XD05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[343]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62747
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01AX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[344]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62791
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[345]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62832
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01CB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[346]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62873
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX21' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EX21)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[347]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62915
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[348]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62955
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01AC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[349]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62997
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XX18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[350]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63042
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (M05BA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[351]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63083
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01BB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[352]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63131
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX71' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XX71)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[353]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63175
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FF09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[354]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63216
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EK03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EK03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[355]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63259
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AC07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[356]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63300
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01CE01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[357]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63341
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L02BA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[358]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63405
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V10XA53' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (V10XA53)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[359]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63448
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01CX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[360]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63490
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EE01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[361]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63533
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[362]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63587
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FD04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[363]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63642
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FD05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[364]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63694
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01FD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[365]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63736
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[366]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63777
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XF01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XF01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[367]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63819
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01AC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[368]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63877
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC59' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01BC59)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[369]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63920
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L02AE04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[370]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63963
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01AA07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[371]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64004
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EH03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EH03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[372]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64045
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01AD08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[373]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64090
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N03AG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (N03AG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[374]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64132
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01DB09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[375]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64174
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[376]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64215
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XK05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[377]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64258
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[378]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64300
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX52' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XX52)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[379]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64342
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01CA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[380]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64384
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01CA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[381]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64424
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01CA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[382]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64465
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01CA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[383]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64507
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01CA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[384]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64549
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XJ01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XJ01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[385]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64592
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L04AD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[386]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64634
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XH01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XH01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[387]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64673
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L02BG05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[388]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64714
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX53' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01XX53)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[389]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64758
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EL03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01EL03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[390]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64803
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (M05BA08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[391]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64844
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2022 (L01DB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2022: ValueSet.compose.include[0].concept[392]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-systemische-therapie-substanzen-2023",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-systemische-therapie-substanzen-2023",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 442
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51301
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51481
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA24' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AA24)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51524
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EF03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EF03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51564
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA22' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AA22)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51606
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L02BX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51651
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EL02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EL02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51694
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01DB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51736
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51776
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[8]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51818
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[9]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51861
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX44' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XX44)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[10]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51904
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L03AC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[11]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51945
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01ED03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[12]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51986
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AA15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[13]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52029
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA34' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AA34)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[14]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52074
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (M05BA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[15]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52118
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XF02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XF02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[16]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52159
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EM03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EM03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[17]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52201
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[18]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52241
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AM01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (V03AM01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[19]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52289
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L02BG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[20]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52338
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XD04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[21]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52381
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FX18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[22]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52422
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01DB10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[23]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52462
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[24]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52503
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX35' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XX35)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[25]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52543
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[26]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52585
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L02BG03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[27]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52659
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[28]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52701
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L02BB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[29]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52745
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX27' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XX27)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[30]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52786
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'P01BE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (P01BE03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[31]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52827
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[32]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52871
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[33]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52915
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FF05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[34]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52958
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EX18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[35]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52998
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FF04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[36]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53052
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XL03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[37]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53092
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EK01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EK01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[38]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53134
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01BC07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[39]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53177
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[40]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53220
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[41]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53265
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L03AX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[42]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53317
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FX15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[43]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53359
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA28' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AA28)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[44]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53400
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA26' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AA26)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[45]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53442
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XH04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XH04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[46]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53484
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX74' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XX74)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[47]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53527
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01AA09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[48]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53570
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[49]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53611
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XF03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XF03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[50]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53654
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L02BB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[51]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53697
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EE03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[52]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53738
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01DC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[53]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53782
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FX07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[54]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53824
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[55]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53865
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[56]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53916
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FX05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[57]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53972
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XL06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[58]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54015
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AC09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[59]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54057
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01ED04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[60]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54101
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N04BC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (N04BC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[61]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54142
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L02AE01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[62]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54182
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[63]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54225
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01CD04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[64]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54267
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N04BC06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (N04BC06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[65]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54311
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EX07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[66]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54361
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (V03AF04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[67]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54404
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AC08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[68]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54447
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01BC06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[69]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54489
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX17' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EX17)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[70]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54532
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[71]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54573
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01AC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[72]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54616
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XG02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XG02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[73]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54656
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01BC04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[74]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54697
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01AD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[75]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54740
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[76]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54782
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FF06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[77]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54823
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01ED02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[78]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54873
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[79]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54915
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (H01CC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[80]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54956
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FE01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[81]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55000
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01AA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[82]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55044
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03DB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (G03DB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[83]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55087
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01AA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[84]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55130
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[85]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55186
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XL05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[86]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55227
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[87]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55268
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01BB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[88]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55312
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (M05BA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[89]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55354
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01BB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[90]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55397
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EE02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[91]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55439
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EM02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EM02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[92]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55481
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01ED01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[93]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55528
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01AA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[94]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55570
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03HA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (G03HA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[95]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55611
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01BC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[96]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55669
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XY01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XY01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[97]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55711
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[98]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55753
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01AX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[99]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55795
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[100]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55838
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EB07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[101]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55882
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01DA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[102]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55925
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[103]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55973
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (B03XA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[104]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56016
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L02BB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[105]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56057
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[106]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56101
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01DB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[107]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56142
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01BC08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[108]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56183
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L02BX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[109]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56225
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01CC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[110]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56275
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX29' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XX29)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[111]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56316
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (M05BX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[112]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56360
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (H02AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[113]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56408
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FX06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[114]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56449
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01CD02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[115]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56492
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FF07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[116]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56535
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01DB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[117]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56577
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FF03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[118]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56619
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G04CB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (G04CB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[119]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56660
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EM04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EM04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[120]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56702
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA25' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AA25)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[121]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56745
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[122]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56787
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA21' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AA21)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[123]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56830
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XD06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[124]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56872
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FX08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[125]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56915
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B02BX05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (B02BX05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[126]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56957
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX59' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XX59)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[127]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57000
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[128]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57050
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FX13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[129]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57093
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EX14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[130]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57136
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L02BB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[131]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57178
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01DB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[132]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57221
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EN01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EN01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[133]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57261
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX41' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XX41)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[134]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57302
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[135]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57348
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (B03XA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[136]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57391
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XX11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[137]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57433
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[138]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57477
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (M05BA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[139]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57518
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01AG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[140]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57558
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01CB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[141]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57600
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EG02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EG02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[142]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57641
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L02BG06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[143]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57683
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EJ02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EJ02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[144]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57725
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L03AA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[145]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57767
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G04CB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (G04CB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[146]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57809
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA27' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AA27)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[147]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57851
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01BC09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[148]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57893
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01BB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[149]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57937
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01BC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[150]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57996
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC52' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01BC52)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[151]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58036
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L02BB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[152]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58082
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (V03AF03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[153]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58123
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L02BG02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[154]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58165
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L02AA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[155]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58209
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B02BX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (B02BX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[156]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58251
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01AD05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[157]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58294
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L02BA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[158]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58337
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EN04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EN04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[159]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58378
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[160]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58420
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01BC05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[161]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58473
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[162]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58515
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L02AB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[163]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58559
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EX13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[164]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58600
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XJ03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XJ03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[165]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58641
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[166]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58684
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (H01CA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[167]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58725
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L02AE03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[168]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58767
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA19' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AA19)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[169]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58821
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L03AX14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[170]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58862
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L02AE05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[171]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58909
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XX05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[172]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58954
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (M05BA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[173]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59010
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V10XX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (V10XX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[174]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59051
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EL01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EL01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[175]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59093
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01DB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[176]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59146
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XL07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[177]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59188
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EM01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EM01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[178]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59229
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01AA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[179]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59269
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[180]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59310
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D06BB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (D06BB10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[181]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59352
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[182]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59398
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D06BX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (D06BX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[183]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59451
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[184]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59509
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L03AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[185]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59559
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L03AB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[186]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59609
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L03AB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[187]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59660
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L03AB18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[188]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59702
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[189]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59744
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CE02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01CE02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[190]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59786
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[191]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59828
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX62' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XX62)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[192]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59870
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01DC04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[193]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59910
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XG03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XG03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[194]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59953
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02CA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (H02CA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[195]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59994
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (H01CB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[196]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60035
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EH01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EH01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[197]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60080
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX12' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EX12)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[198]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60122
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EB09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[199]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60164
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AA13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[200]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60207
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[201]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60250
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L03AA10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[202]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60292
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EX08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[203]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60332
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L02BG04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[204]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60375
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L02AE02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[205]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60422
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L03AA14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[206]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60477
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XL08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[207]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60517
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01AD02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[208]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60559
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'A16AX20' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (A16AX20)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[209]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60600
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XX07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[210]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60642
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01ED05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[211]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60687
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX69' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XX69)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[212]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60731
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (B03XA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[213]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60774
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03DC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (G03DC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[214]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60817
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01AB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[215]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60858
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'J05AX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (J05AX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[216]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60902
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FD06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[217]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60944
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XX10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[218]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60994
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L02AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[219]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61035
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L02AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[220]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61076
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01AA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[221]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61119
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'R03DX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (R03DX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[222]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61164
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01BB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[223]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61201
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (V03AF01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[224]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61241
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N07BC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (N07BC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[225]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61284
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01BA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[226]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61327
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XD10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[227]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61397
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (B03XA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[228]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61449
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[229]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61498
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (H02AB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[230]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61541
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EX10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[231]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61583
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L03AX15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[232]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61625
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[233]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61668
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CH01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01CH01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[234]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61711
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CP01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01CP01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[235]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61755
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01AX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[236]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61797
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX16' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XX16)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[237]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61838
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01DC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[238]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61877
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX23' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XX23)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[239]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61920
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01DB07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[240]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61964
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EB10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[241]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62009
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[242]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62053
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L03AA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[243]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62096
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX24' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FX24)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[244]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62141
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX25' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FX25)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[245]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62194
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[246]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62239
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[247]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62286
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[248]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62329
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA23' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AA23)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[249]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62379
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (V03AF10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[250]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62422
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FE03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[251]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62463
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01BB07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[252]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62504
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EH02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EH02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[253]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62545
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[254]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62586
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L02BB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[255]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62626
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01AD06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[256]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62668
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[257]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62709
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XK02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[258]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62750
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FF01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[259]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62806
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XY03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XY03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[260]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62850
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[261]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62892
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX36' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XX36)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[262]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62933
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (H01CB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[263]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62975
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[264]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63015
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XK01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[265]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63057
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FX10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[266]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63111
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX40' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XX40)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[267]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63162
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX16' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FX16)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[268]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63204
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L03AC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[269]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63247
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[270]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63290
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[271]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63332
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01CD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[272]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63384
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01CD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[273]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63426
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EJ03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EJ03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[274]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63469
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EF01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EF01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[275]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63511
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (V03AF08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[276]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63556
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (M05BA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[277]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63599
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FE02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FE02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[278]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63643
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XH03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XH03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[279]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63684
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[280]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63728
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX24' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XX24)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[281]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63773
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L03AA13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[282]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63826
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L03AB11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[283]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63879
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L03AB10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[284]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63924
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FF02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[285]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63966
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01BA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[286]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64009
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EN02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EN02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[287]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64052
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XX08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[288]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64094
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FD02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[289]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64152
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XY02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XY02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[290]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64194
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01AX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[291]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64237
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01DB08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[292]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64278
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01DB11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[293]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64317
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AX10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (V03AX10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[294]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64359
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX16' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L03AX16)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[295]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64401
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01DC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[296]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64452
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FX14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[297]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64493
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L03AX08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[298]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64546
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L02AA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[299]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64591
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[300]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64634
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AX06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[301]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64675
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[302]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64723
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[303]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64766
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01BA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[304]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64809
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX23' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EX23)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[305]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64853
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D07AC18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (D07AC18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[306]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64897
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01AA08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[307]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64940
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (H02AB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[308]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64981
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (H02AB07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[309]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65024
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[310]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65087
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D05AD' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (D05AD)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[311]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65153
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D05BA' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (D05BA)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[312]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65196
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EX11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[313]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65237
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03XC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (G03XC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[314]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65280
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01BA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[315]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65323
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FG02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FG02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[316]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65365
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01AD07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[317]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65408
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EX05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[318]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65449
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L02BX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[319]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65493
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FF10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[320]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65535
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EF02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EF02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[321]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65577
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AC04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[322]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65619
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX19' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EX19)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[323]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65664
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (M05BA07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[324]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65705
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[325]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65747
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XH02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XH02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[326]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65790
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B02BX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (B02BX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[327]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65845
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L03AB15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[328]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65886
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XK03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[329]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65929
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EJ01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EJ01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[330]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65972
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX19' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FX19)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[331]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66025
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX17' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FX17)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[332]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66068
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[333]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66109
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX66' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XX66)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[334]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66154
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX22' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EX22)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[335]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66197
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EE04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[336]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66237
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01AD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[337]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66279
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AC11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[338]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66320
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AA10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[339]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66373
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XL01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[340]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66417
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (H01CB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[341]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66458
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XJ02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XJ02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[342]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66499
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[343]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66540
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX73' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XX73)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[344]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66584
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01AD04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[345]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66625
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[346]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66667
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AD02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[347]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66710
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX12' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FX12)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[348]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66753
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX67' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XX67)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[349]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66796
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XK04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[350]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66851
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XL02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[351]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66892
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L02BA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[352]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66934
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L03AX11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[353]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66978
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX72' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XX72)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[354]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67021
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX75' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XX75)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[355]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67075
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC53' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01BC53)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[356]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67125
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC63' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01BC63)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[357]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67188
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC73' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01BC73)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[358]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67230
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XD05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[359]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67273
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01AX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[360]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67317
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[361]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67358
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01CB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[362]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67399
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX21' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EX21)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[363]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67441
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[364]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67481
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01AC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[365]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67523
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XX18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[366]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67568
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (M05BA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[367]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67609
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01BB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[368]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67657
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XL04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[369]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67701
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FF09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[370]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67742
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EK03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EK03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[371]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67785
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AC07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[372]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67826
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01CE01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[373]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67867
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L02BA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[374]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67931
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V10XA53' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (V10XA53)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[375]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67974
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01CX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[376]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68016
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EE01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[377]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68059
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[378]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68113
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FD04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[379]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68168
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FD05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[380]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68220
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[381]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68264
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX20' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01FX20)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[382]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68306
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[383]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68347
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XF01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XF01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[384]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68389
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01AC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[385]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68447
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC59' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01BC59)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[386]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68490
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L02AE04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[387]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68533
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01AA07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[388]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68574
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EH03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EH03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[389]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68615
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01AD08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[390]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68660
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N03AG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (N03AG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[391]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68702
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01DB09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[392]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68744
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[393]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68785
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XK05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[394]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68828
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[395]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68870
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX52' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XX52)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[396]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68912
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01CA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[397]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68954
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01CA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[398]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68994
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01CA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[399]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69035
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01CA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[400]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69077
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01CA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[401]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69119
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XJ01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XJ01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[402]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69162
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L04AD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[403]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69204
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XH01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XH01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[404]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69243
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L02BG05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[405]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69284
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX53' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01XX53)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[406]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69328
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EL03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01EL03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[407]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69373
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (M05BA08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[408]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69414
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2023 (L01DB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2023: ValueSet.compose.include[0].concept[409]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-systemische-therapie-substanzen-2024",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-systemische-therapie-substanzen-2024",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 442
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49865
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50045
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA24' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AA24)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50088
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EF03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EF03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50128
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA22' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AA22)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50170
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L02BX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50215
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EL02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EL02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50258
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01DB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50299
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX77' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XX77)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50341
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[8]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50381
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[9]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50423
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[10]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50466
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX44' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XX44)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[11]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50509
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L03AC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[12]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50550
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01ED03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[13]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50591
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AA15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[14]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50634
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AG06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AG06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[15]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50679
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (M05BA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[16]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50723
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XF02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XF02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[17]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50764
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EM03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EM03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[18]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50806
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[19]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50846
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AM01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (V03AM01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[20]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50894
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L02BG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[21]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50943
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XD04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[22]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50986
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FX18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[23]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51027
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01DB10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[24]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51067
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[25]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51108
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX35' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XX35)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[26]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51148
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[27]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51190
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L02BG03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[28]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51264
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[29]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51306
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L02BB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[30]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51350
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX27' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XX27)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[31]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51391
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'P01BE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (P01BE03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[32]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51432
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[33]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[34]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51520
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FF05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[35]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51563
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EX18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[36]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51603
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FF04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[37]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51657
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XL03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[38]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51697
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EK01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EK01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[39]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51739
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01BC07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[40]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51782
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[41]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51825
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[42]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51870
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L03AX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[43]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51922
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FX15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[44]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51964
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA28' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AA28)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[45]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52005
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AG04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AG04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[46]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52047
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XH04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XH04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[47]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52089
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX74' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XX74)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[48]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52132
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01AA09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[49]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52175
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[50]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52216
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XF03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XF03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[51]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52259
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L02BB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[52]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52302
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EE03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[53]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52343
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01DC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[54]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52387
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FX07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[55]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52429
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[56]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52470
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[57]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52521
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FX05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[58]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52577
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XL06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[59]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52620
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AC09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[60]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52662
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01ED04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[61]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52706
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N04BC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (N04BC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[62]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52747
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L02AE01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[63]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52787
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[64]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52830
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01CD04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[65]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52872
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N04BC06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (N04BC06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[66]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52916
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EX07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[67]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52966
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (V03AF04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[68]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53009
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AC08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[69]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53052
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01BC06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[70]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53094
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX17' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EX17)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[71]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53137
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[72]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53178
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01AC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[73]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53221
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XG02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XG02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[74]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53261
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01BC04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[75]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53302
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01AD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[76]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53345
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[77]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53387
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FF06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[78]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53428
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01ED02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[79]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53478
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[80]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53520
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (H01CC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[81]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53561
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FE01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[82]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53605
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01AA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[83]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53649
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03DB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (G03DB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[84]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53692
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01AA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[85]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53735
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[86]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53791
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XL05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[87]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53832
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[88]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53873
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01BB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[89]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53917
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (M05BA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[90]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53959
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01BB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[91]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54002
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EE02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[92]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54044
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EM02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EM02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[93]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54086
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01ED01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[94]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54133
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01AA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[95]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54175
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03HA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (G03HA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[96]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54216
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01BC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[97]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54274
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XY01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XY01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[98]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54316
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[99]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54358
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01AX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[100]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54400
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[101]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54443
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EB07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[102]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54487
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01DA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[103]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54530
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[104]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54578
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (B03XA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[105]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54621
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L02BB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[106]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54662
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[107]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54706
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01DB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[108]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54747
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01BC08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[109]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54788
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L02BX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[110]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54830
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01CC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[111]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54880
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX29' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XX29)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[112]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54921
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (M05BX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[113]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54965
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (H02AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[114]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55013
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FX06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[115]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55054
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01CD02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[116]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55097
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FF07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[117]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55140
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01DB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[118]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55182
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FF03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[119]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55224
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G04CB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (G04CB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[120]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55265
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EM04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EM04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[121]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55307
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AJ01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AJ01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[122]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55350
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[123]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55392
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AG02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AG02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[124]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55435
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XD06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[125]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55478
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L02BA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[126]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55520
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FX08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[127]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55563
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B02BX05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (B02BX05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[128]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55605
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX59' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XX59)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[129]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55648
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[130]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55698
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FX13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[131]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55741
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EX14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[132]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55784
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L02BB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[133]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55826
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01DB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[134]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55869
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EN01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EN01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[135]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55909
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX41' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XX41)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[136]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55950
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[137]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55996
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (B03XA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[138]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56039
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XX11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[139]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56081
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[140]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56125
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (M05BA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[141]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56166
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01AG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[142]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56206
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01CB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[143]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56248
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EG02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EG02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[144]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56290
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AH02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AH02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[145]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56331
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L02BG06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[146]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56373
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EJ02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EJ02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[147]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56415
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L03AA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[148]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56457
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G04CB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (G04CB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[149]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56499
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AE01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[150]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56541
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01BC09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[151]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56583
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01BB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[152]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56627
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01BC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[153]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56686
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC52' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01BC52)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[154]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56726
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L02BB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[155]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56772
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (V03AF03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[156]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56813
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L02BG02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[157]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56855
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L02AA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[158]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56899
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B02BX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (B02BX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[159]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56941
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01AD05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[160]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56985
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EK04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EK04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[161]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57028
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L02BA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[162]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57071
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EN04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EN04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[163]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57112
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[164]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57154
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01BC05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[165]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57207
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[166]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57249
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L02AB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[167]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57293
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EX13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[168]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57334
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XJ03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XJ03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[169]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57375
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[170]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57418
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (H01CA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[171]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57459
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L02AE03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[172]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57501
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA19' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AA19)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[173]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57555
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L03AX14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[174]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57596
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L02AE05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[175]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57643
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XX05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[176]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57688
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (M05BA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[177]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57744
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V10XX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (V10XX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[178]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57785
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EL01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EL01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[179]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57827
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01DB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[180]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57880
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XL07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[181]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57922
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EM01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EM01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[182]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57963
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01AA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[183]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58003
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[184]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58044
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D06BB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (D06BB10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[185]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58086
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[186]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58132
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D06BX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (D06BX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[187]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58185
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[188]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58243
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L03AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[189]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58293
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L03AB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[190]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58343
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L03AB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[191]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58394
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L03AB18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[192]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58436
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[193]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58478
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CE02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01CE02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[194]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58520
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[195]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58562
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX62' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XX62)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[196]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58604
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01DC04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[197]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58644
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XG03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XG03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[198]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58687
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02CA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (H02CA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[199]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58728
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (H01CB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[200]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58769
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EH01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EH01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[201]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58814
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX12' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EX12)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[202]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58856
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EB09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[203]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58898
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AK01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AK01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[204]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58941
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[205]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58984
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L03AA10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[206]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59026
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EX08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[207]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59066
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L02BG04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[208]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59109
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L02AE02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[209]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59156
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L03AA14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[210]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59211
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XL08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[211]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59251
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01AD02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[212]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59293
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'A16AX20' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (A16AX20)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[213]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59334
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XX07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[214]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59376
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01ED05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[215]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59421
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX69' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XX69)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[216]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59465
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (B03XA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[217]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59508
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03DC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (G03DC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[218]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59551
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01AB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[219]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59592
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'J05AX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (J05AX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[220]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59636
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FD06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[221]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59678
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XX10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[222]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59728
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L02AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[223]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59769
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L02AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[224]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59810
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01AA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[225]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59853
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'R03DX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (R03DX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[226]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59898
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01BB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[227]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59935
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (V03AF01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[228]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59975
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N07BC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (N07BC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[229]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60018
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01BA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[230]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60061
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XD10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[231]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60131
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (B03XA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[232]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60183
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[233]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60232
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (H02AB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[234]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60275
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EX10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[235]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60317
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L03AX15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[236]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60359
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[237]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60402
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CH01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01CH01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[238]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60445
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CP01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01CP01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[239]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60489
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01AX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[240]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60531
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX16' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XX16)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[241]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60572
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01DC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[242]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60611
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX23' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XX23)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[243]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60654
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01DB07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[244]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60698
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EB10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[245]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60743
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[246]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60787
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L03AA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[247]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60830
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX24' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FX24)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[248]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60875
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX25' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FX25)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[249]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60928
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[250]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60973
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[251]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61020
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[252]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61063
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AG03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AG03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[253]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61113
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (V03AF10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[254]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61156
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FE03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[255]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61197
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01BB07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[256]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61238
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EH02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EH02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[257]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61279
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[258]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61320
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L02BB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[259]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61360
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01AD06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[260]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61402
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[261]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61443
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XK02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[262]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61484
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FF01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[263]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61540
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FY02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FY02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[264]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61584
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[265]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61626
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX36' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XX36)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[266]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61667
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (H01CB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[267]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61709
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[268]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61751
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AG12' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AG12)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[269]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61791
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XK01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[270]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61833
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FX10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[271]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61887
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX40' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XX40)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[272]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61938
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX16' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FX16)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[273]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61980
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L03AC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[274]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62023
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[275]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62066
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[276]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62108
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01CD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[277]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62160
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01CD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[278]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62202
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EJ03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EJ03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[279]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62245
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EF01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EF01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[280]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62287
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (V03AF08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[281]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62332
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (M05BA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[282]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62375
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FE02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FE02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[283]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62419
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XH03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XH03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[284]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62460
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[285]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62504
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX24' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XX24)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[286]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62549
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L03AA13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[287]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62602
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L03AB11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[288]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62655
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L03AB10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[289]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62700
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FF02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[290]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62742
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01BA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[291]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62785
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EN02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EN02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[292]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62828
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XX08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[293]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62870
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FD02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[294]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62928
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FY01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FY01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[295]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62970
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01AX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[296]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63013
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01DB08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[297]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63054
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01DB11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[298]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63093
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AX10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (V03AX10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[299]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63135
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX16' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L03AX16)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[300]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63177
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01DC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[301]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63228
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FX14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[302]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63269
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L03AX08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[303]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63322
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L02AA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[304]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63367
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[305]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63410
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AX06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[306]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63451
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[307]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63499
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[308]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63542
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01BA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[309]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63585
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX23' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EX23)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[310]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63629
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D07AC18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (D07AC18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[311]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63673
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01AA08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[312]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63716
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (H02AB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[313]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63757
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (H02AB07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[314]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63800
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[315]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63863
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D05AD' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (D05AD)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[316]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63929
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D05BA' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (D05BA)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[317]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63972
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EX11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[318]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64013
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03XC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (G03XC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[319]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64056
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01BA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[320]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64099
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FG02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FG02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[321]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64141
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01AD07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[322]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64184
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EX05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[323]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64225
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L02BX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[324]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64269
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FF10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[325]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64311
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EF02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EF02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[326]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64353
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AC04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[327]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64395
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX19' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EX19)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[328]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64440
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (M05BA07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[329]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64481
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[330]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64523
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XH02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XH02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[331]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64566
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B02BX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (B02BX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[332]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64621
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L03AB15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[333]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64662
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XK03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[334]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64705
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EJ01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EJ01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[335]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64748
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX19' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FX19)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[336]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64801
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX17' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FX17)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[337]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64844
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[338]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64885
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX66' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XX66)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[339]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64930
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX22' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EX22)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[340]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64973
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EE04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[341]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65013
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01AD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[342]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65055
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AC11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[343]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65096
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AH01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AH01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[344]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65149
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XL01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[345]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65193
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (H01CB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[346]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65234
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XJ02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XJ02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[347]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65275
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[348]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65316
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX73' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XX73)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[349]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65360
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01AD04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[350]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65403
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FF11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[351]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65444
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[352]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65486
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AD02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[353]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65529
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX12' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FX12)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[354]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65572
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX67' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XX67)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[355]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65615
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XK04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[356]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65670
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XL02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[357]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65713
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX29' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FX29)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[358]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65754
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L02BA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[359]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65796
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L03AX11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[360]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65840
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX72' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XX72)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[361]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65883
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX75' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XX75)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[362]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65937
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC53' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01BC53)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[363]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65987
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC63' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01BC63)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[364]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66050
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC73' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01BC73)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[365]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66092
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XD05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[366]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66135
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01AX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[367]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66179
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[368]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66220
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01CB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[369]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66261
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX21' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EX21)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[370]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66303
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[371]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66343
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01AC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[372]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66385
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XX18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[373]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66430
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (M05BA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[374]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66471
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01BB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[375]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66519
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XL04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[376]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66563
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FF09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[377]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66604
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EK03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EK03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[378]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66647
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AC07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[379]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66688
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01CE01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[380]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66729
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L02BA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[381]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66793
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V10XA53' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (V10XA53)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[382]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66836
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01CX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[383]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66878
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EE01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[384]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66921
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[385]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66975
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FD04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[386]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67030
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FD05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[387]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67082
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[388]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67126
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX20' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01FX20)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[389]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67168
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[390]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67209
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XF01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XF01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[391]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67251
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01AC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[392]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67309
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC59' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01BC59)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[393]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67352
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L02AE04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[394]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67395
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01AA07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[395]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67436
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EH03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EH03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[396]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67477
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01AD08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[397]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67522
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N03AG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (N03AG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[398]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67564
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01DB09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[399]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67606
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[400]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67647
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XK05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[401]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67690
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[402]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67732
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX52' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XX52)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[403]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67774
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01CA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[404]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67816
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01CA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[405]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67856
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01CA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[406]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67897
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01CA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[407]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67939
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01CA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[408]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67981
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XJ01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XJ01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[409]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68024
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L04AD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[410]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68066
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XH01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XH01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[411]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68105
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L02BG05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[412]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68146
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX53' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01XX53)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[413]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68190
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EL03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01EL03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[414]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68235
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (M05BA08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[415]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68276
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2024 (L01DB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2024: ValueSet.compose.include[0].concept[416]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-systemische-therapie-substanzen-2025",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-systemische-therapie-substanzen-2025",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 442
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50401
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50581
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA24' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AA24)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50624
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EF03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EF03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50664
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA22' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AA22)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50706
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L02BX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50751
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EL02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EL02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50794
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01DB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50835
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX77' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XX77)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50877
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[8]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50917
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[9]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50959
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[10]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51002
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX44' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XX44)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[11]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51045
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L03AC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[12]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51086
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01ED03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[13]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51127
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AA15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[14]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51170
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AG06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AG06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[15]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51215
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (M05BA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[16]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51259
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XF02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XF02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[17]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51300
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EM03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EM03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[18]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51342
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[19]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51382
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AM01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (V03AM01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[20]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51430
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L02BG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[21]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51479
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XD04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[22]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51522
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FX18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[23]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51563
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01DB10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[24]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51603
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[25]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51644
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX35' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XX35)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[26]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51684
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[27]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51726
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L02BG03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[28]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51800
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[29]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51842
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L02BB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[30]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51886
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX27' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XX27)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[31]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51927
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'P01BE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (P01BE03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[32]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51968
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[33]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52012
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[34]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52056
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FF05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[35]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52099
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EX18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[36]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52139
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FF04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[37]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52193
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XL03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[38]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52233
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EK01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EK01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[39]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52275
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01BC07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[40]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52318
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[41]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52361
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[42]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52406
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L03AX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[43]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52458
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FX15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[44]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52500
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA28' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AA28)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[45]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52541
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AG04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AG04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[46]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52583
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XH04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XH04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[47]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52625
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX74' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XX74)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[48]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52668
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01AA09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[49]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52711
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[50]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52752
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XF03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XF03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[51]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52795
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L02BB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[52]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52838
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EE03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[53]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52879
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01DC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[54]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52923
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FX07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[55]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52965
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[56]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53006
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[57]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53057
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FX05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[58]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53113
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XL06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[59]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53156
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AC09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[60]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53198
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01ED04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[61]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53242
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N04BC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (N04BC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[62]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53283
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L02AE01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[63]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53323
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[64]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53366
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01CD04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[65]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53408
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N04BC06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (N04BC06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[66]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53452
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EX07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[67]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53502
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (V03AF04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[68]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53545
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AC08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[69]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53588
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01BC06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[70]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53632
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX27' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EX27)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[71]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53674
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX17' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EX17)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[72]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53717
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[73]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53758
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01AC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[74]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53801
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XG02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XG02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[75]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53841
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01BC04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[76]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53882
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01AD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[77]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53925
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[78]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53967
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FF06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[79]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54008
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01ED02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[80]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54058
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[81]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54100
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (H01CC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[82]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54141
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FE01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[83]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54185
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01AA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[84]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54229
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03DB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (G03DB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[85]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54272
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01AA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[86]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54315
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[87]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54371
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XL05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[88]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54412
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[89]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54453
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01BB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[90]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54497
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (M05BA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[91]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54539
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01BB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[92]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54582
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EE02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[93]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54624
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EM02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EM02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[94]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54666
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01ED01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[95]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54713
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01AA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[96]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54755
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03HA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (G03HA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[97]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54796
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01BC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[98]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54854
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XY01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XY01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[99]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54896
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[100]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54938
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01AX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[101]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54980
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[102]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55023
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EB07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[103]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55067
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01DA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[104]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55110
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[105]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55158
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (B03XA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[106]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55201
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L02BB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[107]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55242
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[108]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55286
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01DB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[109]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55327
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01BC08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[110]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55368
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L02BX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[111]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55410
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01CC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[112]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55460
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX29' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XX29)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[113]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55501
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (M05BX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[114]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55545
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (H02AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[115]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55593
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FX06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[116]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55634
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01CD02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[117]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55677
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FF07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[118]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55720
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01DB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[119]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55762
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FF03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[120]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55804
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G04CB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (G04CB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[121]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55845
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EM04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EM04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[122]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55887
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AJ01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AJ01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[123]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55930
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[124]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55972
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AG02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AG02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[125]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56015
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XD06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[126]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56058
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L02BA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[127]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56100
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FX08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[128]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56143
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B02BX05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (B02BX05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[129]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56185
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XM01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XM01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[130]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56228
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[131]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56278
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FX13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[132]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56321
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EX14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[133]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56364
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L02BB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[134]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56407
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX27' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FX27)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[135]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56449
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01DB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[136]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56492
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EN01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EN01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[137]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56532
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX41' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XX41)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[138]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56573
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[139]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56619
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (B03XA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[140]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56662
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XX11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[141]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56704
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[142]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56748
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (M05BA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[143]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56789
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01AG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[144]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56829
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01CB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[145]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56871
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EG02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EG02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[146]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56913
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AH02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AH02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[147]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56954
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L02BG06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[148]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56996
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EJ02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EJ02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[149]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57038
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L03AA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[150]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57080
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G04CB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (G04CB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[151]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57122
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AE01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[152]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57164
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01BC09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[153]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57206
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01BB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[154]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57250
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01BC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[155]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57309
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC52' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01BC52)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[156]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57349
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L02BB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[157]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57395
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (V03AF03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[158]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57436
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L02BG02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[159]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57478
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L02AA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[160]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57522
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B02BX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (B02BX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[161]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57564
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01AD05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[162]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57608
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EK04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EK04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[163]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57651
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L02BA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[164]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57694
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EN04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EN04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[165]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57735
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[166]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57777
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01BC05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[167]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57830
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[168]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57872
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L02AB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[169]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57916
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EX13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[170]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57957
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XJ03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XJ03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[171]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57998
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[172]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58041
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (H01CA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[173]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58082
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L02AE03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[174]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58124
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA19' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AA19)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[175]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58178
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L03AX14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[176]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58219
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L02AE05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[177]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58266
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XX05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[178]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58311
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (M05BA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[179]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58367
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V10XX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (V10XX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[180]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58408
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EL01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EL01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[181]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58450
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01DB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[182]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58503
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XL07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[183]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58545
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EM01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EM01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[184]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58586
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01AA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[185]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58626
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[186]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58667
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D06BB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (D06BB10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[187]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58709
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[188]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58755
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D06BX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (D06BX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[189]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58808
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[190]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58866
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L03AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[191]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58916
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L03AB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[192]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58966
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L03AB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[193]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59017
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L03AB18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[194]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59059
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[195]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59101
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CE02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01CE02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[196]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59143
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[197]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59185
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XM02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XM02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[198]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59227
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01DC04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[199]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59267
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XG03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XG03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[200]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59310
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02CA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (H02CA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[201]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59351
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (H01CB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[202]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59392
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EH01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EH01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[203]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59437
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX12' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EX12)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[204]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59479
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EB09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[205]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59521
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AK01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AK01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[206]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59564
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[207]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59607
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L03AA10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[208]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59649
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EX08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[209]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59689
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L02BG04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[210]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59732
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L02AE02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[211]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59779
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L03AA14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[212]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59834
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XL08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[213]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59874
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01AD02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[214]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59916
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'A16AX20' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (A16AX20)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[215]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59957
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XX07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[216]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59999
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01ED05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[217]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60044
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX69' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XX69)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[218]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60088
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (B03XA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[219]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60131
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03DC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (G03DC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[220]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60174
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01AB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[221]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60215
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'J05AX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (J05AX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[222]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60259
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FD06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[223]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60301
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XX10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[224]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60351
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L02AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[225]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60392
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L02AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[226]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60433
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01AA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[227]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'R03DX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (R03DX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[228]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60521
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01BB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[229]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60558
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (V03AF01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[230]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60598
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N07BC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (N07BC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[231]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60641
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01BA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[232]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60684
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XD10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[233]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60754
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (B03XA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[234]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60806
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[235]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60855
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (H02AB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[236]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60898
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EX10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[237]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60940
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L03AX15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[238]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60982
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[239]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61025
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CH01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01CH01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[240]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61068
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CP01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01CP01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[241]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61112
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01AX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[242]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61154
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX16' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XX16)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[243]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61195
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01DC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[244]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61234
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX23' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XX23)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[245]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61277
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01DB07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[246]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61321
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EB10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[247]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61366
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[248]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61410
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L03AA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[249]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61453
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX24' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FX24)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[250]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61498
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX25' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FX25)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[251]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61551
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[252]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61596
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[253]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61643
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[254]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61686
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AG03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AG03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[255]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61736
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (V03AF10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[256]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61778
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX78' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XX78)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[257]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61821
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FE03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[258]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61862
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01BB07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[259]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61903
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EH02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EH02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[260]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61944
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[261]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61985
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L02BB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[262]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62025
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01AD06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[263]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62067
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[264]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62108
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XK02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[265]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62149
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FF01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[266]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62205
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FY02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FY02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[267]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62249
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[268]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62291
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX36' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XX36)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[269]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62332
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (H01CB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[270]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62374
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[271]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62416
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AG12' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AG12)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[272]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62456
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XK01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[273]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62498
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FX10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[274]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62552
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX40' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XX40)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[275]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62603
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX16' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FX16)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[276]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62645
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L03AC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[277]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62688
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[278]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62731
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[279]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62773
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01CD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[280]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62825
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01CD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[281]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62867
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EJ03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EJ03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[282]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62910
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EF01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EF01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[283]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62952
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (V03AF08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[284]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62997
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (M05BA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[285]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63040
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FE02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FE02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[286]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63084
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XH03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XH03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[287]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63125
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[288]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63169
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX24' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XX24)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[289]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63214
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L03AA13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[290]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63267
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L03AB11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[291]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63320
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L03AB10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[292]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63365
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FF02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[293]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63407
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01BA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[294]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63450
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EN02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EN02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[295]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63493
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XX08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[296]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63535
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FD02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[297]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63593
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FY01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FY01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[298]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63635
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01AX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[299]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63678
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01DB08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[300]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63719
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01DB11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[301]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63758
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AX10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (V03AX10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[302]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63800
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX16' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L03AX16)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[303]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63842
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01DC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[304]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63893
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FX14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[305]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63934
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L03AX08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[306]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63987
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L02AA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[307]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64032
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[308]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64075
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AX06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[309]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64116
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[310]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64164
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[311]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64207
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01BA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[312]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64250
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX23' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EX23)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[313]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64294
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D07AC18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (D07AC18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[314]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64338
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01AA08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[315]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64381
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (H02AB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[316]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64422
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (H02AB07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[317]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64465
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[318]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64528
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D05AD' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (D05AD)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[319]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64594
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D05BA' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (D05BA)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[320]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64637
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EX11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[321]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64678
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03XC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (G03XC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[322]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64721
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01BA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[323]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64764
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FG02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FG02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[324]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64806
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01AD07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[325]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64849
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EX05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[326]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64890
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L02BX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[327]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64934
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FF10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[328]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64976
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EF02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EF02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[329]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65018
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AC04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[330]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65060
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX19' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EX19)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[331]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65105
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (M05BA07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[332]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65146
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[333]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65188
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XH02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XH02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[334]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65231
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B02BX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (B02BX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[335]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65286
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L03AB15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[336]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65327
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XK03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[337]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65370
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EJ01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EJ01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[338]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65413
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX19' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FX19)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[339]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65466
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX17' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FX17)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[340]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65509
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[341]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65550
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX66' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XX66)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[342]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65595
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX22' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EX22)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[343]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65638
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EE04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[344]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65678
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01AD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[345]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65720
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AC11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[346]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65761
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AH01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AH01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[347]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65814
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XL01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[348]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65858
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (H01CB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[349]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65899
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XJ02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XJ02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[350]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65940
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[351]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65981
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX73' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XX73)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[352]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66025
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01AD04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[353]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66068
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FF11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[354]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66109
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[355]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66151
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AD02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[356]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66194
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX12' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FX12)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[357]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66237
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX67' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XX67)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[358]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66280
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XK04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[359]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66335
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XL02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[360]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66378
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX29' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FX29)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[361]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66419
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L02BA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[362]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66461
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L03AX11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[363]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66505
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX72' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XX72)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[364]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66548
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX75' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XX75)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[365]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66602
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC53' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01BC53)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[366]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66652
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC63' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01BC63)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[367]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66715
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC73' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01BC73)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[368]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66757
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XD05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[369]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66800
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01AX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[370]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66844
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[371]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66885
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01CB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[372]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66926
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX21' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EX21)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[373]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66968
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[374]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67008
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01AC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[375]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67050
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XX18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[376]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67095
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (M05BA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[377]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67136
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01BB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[378]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67184
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XL04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[379]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67228
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FF09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[380]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67269
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EK03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EK03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[381]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67312
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AC07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[382]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67353
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01CE01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[383]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67394
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L02BA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[384]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67437
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FF13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[385]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67501
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V10XA53' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (V10XA53)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[386]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67544
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01CX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[387]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67586
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EE01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[388]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67629
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[389]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67683
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FD04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[390]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67738
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FD05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[391]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67790
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[392]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67834
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX20' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01FX20)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[393]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67876
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[394]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67917
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XF01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XF01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[395]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67959
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01AC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[396]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68017
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC59' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01BC59)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[397]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68060
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L02AE04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[398]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68103
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01AA07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[399]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68144
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EH03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EH03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[400]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68185
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01AD08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[401]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68230
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N03AG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (N03AG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[402]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68272
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01DB09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[403]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68314
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[404]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68355
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XK05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[405]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68398
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[406]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68440
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX52' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XX52)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[407]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68482
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01CA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[408]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68524
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01CA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[409]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68564
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01CA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[410]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68605
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01CA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[411]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68647
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01CA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[412]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68689
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XJ01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XJ01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[413]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68732
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L04AD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[414]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68774
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XH01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XH01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[415]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68813
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L02BG05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[416]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68854
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX53' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01XX53)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[417]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68898
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EL03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01EL03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[418]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68943
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (M05BA08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[419]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68984
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2025 (L01DB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2025: ValueSet.compose.include[0].concept[420]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-systemische-therapie-substanzen-2026",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-systemische-therapie-substanzen-2026",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 442
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47583
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47763
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA24' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AA24)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47806
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EF03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EF03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47846
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA22' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AA22)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47888
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L02BX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47933
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EL02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EL02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 47976
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01DB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48017
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX77' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX77)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48059
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[8]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48099
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[9]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48141
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[10]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48184
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX44' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX44)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[11]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48227
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L03AC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[12]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48268
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01ED03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[13]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48309
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AA15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[14]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48352
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AG06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AG06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[15]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48397
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (M05BA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[16]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48441
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XF02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XF02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[17]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48482
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EM03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EM03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[18]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48524
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[19]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48564
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AM01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (V03AM01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[20]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48612
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L02BG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[21]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48661
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XD04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[22]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48704
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FX18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[23]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48745
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01DB10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[24]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48785
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[25]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48826
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX35' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX35)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[26]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48866
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[27]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48908
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L02BG03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[28]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 48982
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[29]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49024
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L02BB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[30]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49068
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX27' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX27)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[31]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49109
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'P01BE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (P01BE03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[32]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49150
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[33]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49194
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[34]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49238
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FF05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[35]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49282
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EB11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[36]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49325
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EX18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[37]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49365
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FF04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[38]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49419
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XL03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[39]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49459
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EK01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EK01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[40]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49501
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01BC07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[41]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49544
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[42]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49587
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[43]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49632
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L03AX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[44]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49684
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FX15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[45]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49726
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA28' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AA28)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[46]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49767
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AG04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AG04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[47]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49809
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XH04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XH04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[48]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49851
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX74' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX74)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[49]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49894
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01AA09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[50]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49937
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[51]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 49978
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XF03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XF03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[52]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50021
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L02BB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[53]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50064
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EE03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[54]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50105
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01DC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[55]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50149
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FX07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[56]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50191
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[57]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50232
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[58]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50283
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FX05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[59]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50339
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XL06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[60]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50382
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AC09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[61]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50424
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01ED04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[62]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50468
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N04BC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (N04BC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[63]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50509
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L02AE01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[64]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50549
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[65]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50592
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01CD04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[66]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50634
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N04BC06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (N04BC06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[67]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50678
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EX07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[68]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50728
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX86' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX86)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[69]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50774
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (V03AF03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[70]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50824
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (V03AF04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[71]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50868
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FF14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[72]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50911
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AC08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[73]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50954
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01BC06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[74]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 50998
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX27' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EX27)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[75]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51040
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EP01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EP01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[76]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51083
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[77]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51124
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01AC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[78]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51167
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XG02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XG02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[79]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51207
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01BC04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[80]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51248
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01AD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[81]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51291
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[82]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51333
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FF06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[83]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51374
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01ED02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[84]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51424
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[85]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51466
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (H01CC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[86]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51507
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FE01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[87]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51551
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01AA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[88]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51595
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03DB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (G03DB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[89]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51638
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01AA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[90]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51681
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[91]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51737
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XL05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[92]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51778
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[93]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51819
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01BB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[94]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51863
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (M05BA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[95]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51905
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01BB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[96]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51948
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EE02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[97]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 51990
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EM02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EM02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[98]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52032
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01ED01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[99]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52079
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01AA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[100]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52121
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03HA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (G03HA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[101]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52162
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01BC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[102]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52220
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XY01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XY01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[103]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52262
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[104]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52304
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01AX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[105]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52346
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[106]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52389
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EB07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[107]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52433
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01DA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[108]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[109]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52524
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (B03XA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[110]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52567
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L02BB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[111]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52608
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[112]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52662
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX35' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FX35)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[113]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52706
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01DB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[114]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52747
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01BC08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[115]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52788
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L02BX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[116]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52830
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01CC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[117]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52880
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX29' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX29)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[118]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52921
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (M05BX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[119]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 52965
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (H02AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[120]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53013
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FX06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[121]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53054
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01CD02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[122]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53097
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FF07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[123]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53140
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01DB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[124]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53182
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FF03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[125]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53224
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G04CB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (G04CB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[126]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53265
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EM04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EM04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[127]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53307
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AJ01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AJ01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[128]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53350
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[129]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53392
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AG02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AG02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[130]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53435
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XD06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[131]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53478
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L02BA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[132]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53520
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FX08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[133]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53563
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B02BX05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (B02BX05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[134]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53605
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XM01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XM01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[135]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53648
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[136]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53698
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FX13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[137]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53741
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EX14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[138]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53784
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FF15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[139]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53827
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L02BB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[140]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53870
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX27' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FX27)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[141]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53912
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01DB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[142]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53955
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EN01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EN01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[143]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 53995
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX41' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX41)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[144]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54036
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[145]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54082
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (B03XA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[146]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54125
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[147]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54167
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[148]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54211
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (M05BA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[149]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54252
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01AG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[150]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54292
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01CB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[151]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54334
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EG02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EG02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[152]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54376
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AH02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AH02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[153]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54417
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L02BG06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[154]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54459
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EJ02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EJ02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[155]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54501
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L03AA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[156]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54543
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G04CB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (G04CB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[157]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54585
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AE01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[158]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54630
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB12' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EB12)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[159]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54672
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01BC09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[160]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54714
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01BB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[161]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54758
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01BC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[162]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54817
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC52' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01BC52)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[163]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54857
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L02BB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[164]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54898
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L02BG02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[165]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54940
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L02AA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[166]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54984
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B02BX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (B02BX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[167]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55026
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01AD05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[168]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55070
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EK04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EK04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[169]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55113
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L02BA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[170]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55156
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EN04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EN04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[171]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55197
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[172]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55239
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01BC05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[173]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55292
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[174]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55334
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L02AB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[175]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55378
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EX13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[176]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55419
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XJ03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XJ03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[177]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55460
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[178]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55503
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (H01CA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[179]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55544
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L02AE03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[180]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55586
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA19' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AA19)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[181]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55640
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L03AX14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[182]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55681
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L02AE05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[183]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55728
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[184]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55773
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (M05BA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[185]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55829
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V10XX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (V10XX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[186]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55870
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EL01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EL01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[187]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55912
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01DB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[188]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55965
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XL07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[189]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56007
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EM01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EM01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[190]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56048
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01AA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[191]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56088
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[192]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56130
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX80' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX80)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[193]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56171
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D06BB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (D06BB10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[194]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56213
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EM06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EM06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[195]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56255
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[196]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56301
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D06BX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (D06BX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[197]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56354
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[198]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56412
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L03AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[199]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56462
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L03AB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[200]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56512
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L03AB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[201]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56563
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L03AB18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[202]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56605
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[203]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56647
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CE02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01CE02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[204]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56689
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[205]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56731
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XM02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XM02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[206]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56773
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01DC04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[207]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56813
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XG03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XG03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[208]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56856
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02CA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (H02CA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[209]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56897
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (H01CB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[210]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56938
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EH01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EH01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[211]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56983
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX12' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EX12)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[212]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57025
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EB09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[213]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57067
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AK01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AK01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[214]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57110
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[215]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57153
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L03AA10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[216]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57195
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EX08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[217]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57235
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L02BG04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[218]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57278
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L02AE02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[219]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57323
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX37' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FX37)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[220]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57370
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L03AA14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[221]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57425
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XL08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[222]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57465
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01AD02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[223]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57507
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'A16AX20' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (A16AX20)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[224]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57548
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[225]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57590
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01ED05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[226]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57635
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX69' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX69)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[227]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57679
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (B03XA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[228]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57722
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03DC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (G03DC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[229]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57765
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01AB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[230]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57806
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'J05AX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (J05AX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[231]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57850
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FD06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[232]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57892
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[233]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57942
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L02AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[234]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57983
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L02AB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[235]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58024
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01AA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[236]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58067
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'R03DX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (R03DX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[237]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58112
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01BB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[238]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58149
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (V03AF01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[239]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58189
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N07BC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (N07BC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[240]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58232
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01BA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[241]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58275
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XD10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[242]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58345
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (B03XA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[243]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58397
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[244]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58446
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (H02AB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[245]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58489
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EX10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[246]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58531
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L03AX15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[247]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58573
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[248]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58617
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EE05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[249]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58660
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CH01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01CH01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[250]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58703
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CP01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01CP01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[251]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58747
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01AX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[252]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58789
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX16' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX16)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[253]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58830
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01DC03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[254]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58869
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX23' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX23)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[255]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58912
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01DB07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[256]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58956
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EB10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[257]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59001
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[258]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59045
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L03AA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[259]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59088
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX24' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FX24)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[260]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59133
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX25' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FX25)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[261]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59186
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[262]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59231
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[263]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59278
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AA06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[264]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59321
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AG03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AG03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[265]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59371
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (V03AF10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[266]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59413
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX78' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX78)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[267]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59456
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FE03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[268]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59497
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01BB07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[269]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59538
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EH02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EH02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[270]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59579
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[271]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59620
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L02BB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[272]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59660
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01AD06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[273]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59702
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EX09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[274]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59743
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XK02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[275]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59787
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX81' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX81)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[276]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59828
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FF01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[277]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59884
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FY02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FY02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[278]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59938
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL12' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XL12)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[279]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59982
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[280]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60024
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX36' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX36)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[281]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60065
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (H01CB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[282]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60109
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX34' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FX34)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[283]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60151
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[284]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60193
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AG12' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AG12)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[285]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60233
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XK01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[286]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60275
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FX10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[287]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60329
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX40' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX40)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[288]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60380
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX16' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FX16)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[289]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60422
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L03AC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[290]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60465
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EB04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[291]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60508
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[292]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60550
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01CD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[293]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60602
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01CD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[294]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60644
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EJ03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EJ03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[295]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60687
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EF01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EF01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[296]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60729
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (V03AF08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[297]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60774
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (M05BA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[298]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60817
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FE02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FE02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[299]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60861
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XH03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XH03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[300]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60914
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX36' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FX36)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[301]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60955
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[302]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60999
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX24' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX24)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[303]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61044
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L03AA13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[304]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61097
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L03AB11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[305]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61150
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L03AB10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[306]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61192
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX84' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX84)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[307]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61237
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FF02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[308]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61279
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01BA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[309]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61322
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EN02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EN02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[310]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61365
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[311]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61407
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FD02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[312]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61465
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FY01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FY01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[313]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61507
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01AX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[314]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61550
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01DB08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[315]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61591
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01DB11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[316]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61630
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AX10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (V03AX10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[317]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61672
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX16' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L03AX16)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[318]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61714
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01DC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[319]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61765
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FX14)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[320]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61806
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L03AX08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[321]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61859
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L02AA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[322]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61904
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[323]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61947
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AX06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[324]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61988
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[325]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62036
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[326]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62079
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01BA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[327]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62122
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX23' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EX23)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[328]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62166
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D07AC18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (D07AC18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[329]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62210
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01AA08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[330]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62253
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (H02AB06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[331]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62294
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (H02AB07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[332]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62337
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[333]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62400
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D05AD' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (D05AD)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[334]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62466
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D05BA' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (D05BA)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[335]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62509
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EX11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[336]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62550
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03XC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (G03XC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[337]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62593
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01BA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[338]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62636
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FG02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FG02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[339]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62678
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01AD07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[340]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62721
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EX05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[341]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62762
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L02BX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[342]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62806
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FF10)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[343]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62848
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EF02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EF02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[344]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62890
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AC04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[345]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62932
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX19' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EX19)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[346]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62977
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (M05BA07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[347]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63018
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[348]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63061
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EK05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EK05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[349]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63103
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XH02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XH02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[350]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63146
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B02BX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (B02BX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[351]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63201
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L03AB15)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[352]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63242
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XK03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[353]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63285
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EJ01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EJ01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[354]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63328
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX19' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FX19)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[355]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63381
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX17' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FX17)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[356]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63424
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[357]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63467
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EP03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EP03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[358]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63508
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX66' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX66)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[359]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63553
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX22' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EX22)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[360]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63596
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EE04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[361]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63636
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01AD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[362]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63678
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AC11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[363]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63719
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AH01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AH01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[364]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63772
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XL01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[365]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63816
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (H01CB01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[366]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63857
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XJ02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XJ02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[367]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63898
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[368]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63939
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX73' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX73)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[369]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63983
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01AD04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[370]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64026
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FF11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[371]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64067
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[372]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64109
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AD02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[373]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64152
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX12' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FX12)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[374]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64195
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX67' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX67)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[375]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64238
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XK04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[376]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64293
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XL02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[377]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64336
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX29' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FX29)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[378]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64377
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L02BA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[379]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64419
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L03AX11)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[380]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64463
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX72' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX72)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[381]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64506
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX75' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX75)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[382]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64560
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC53' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01BC53)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[383]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64610
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC63' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01BC63)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[384]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64673
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC73' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01BC73)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[385]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64715
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XD05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[386]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64758
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01AX03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[387]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64802
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[388]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64843
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01CB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[389]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64884
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EP02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EP02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[390]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64926
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AX02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[391]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64966
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01AC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[392]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65008
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX18)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[393]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65053
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (M05BA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[394]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65094
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01BB03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[395]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65142
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XL04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[396]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65186
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FF09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[397]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65227
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EK03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EK03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[398]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65270
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AC07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[399]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65311
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01CE01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[400]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65352
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L02BA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[401]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65395
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FF13)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[402]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65459
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V10XA53' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (V10XA53)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[403]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65502
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EC04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EC04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[404]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65545
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01CX01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[405]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65587
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EE01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[406]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65630
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FD01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[407]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65684
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FD04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[408]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65739
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FD05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[409]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65791
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[410]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65835
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX20' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FX20)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[411]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65877
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01AB02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[412]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65918
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XF01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XF01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[413]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65960
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01AC02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[414]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66018
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC59' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01BC59)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[415]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66061
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L02AE04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[416]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66104
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01AA07)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[417]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66145
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EH03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EH03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[418]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66189
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EE06)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[419]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66230
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01AD08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[420]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66275
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N03AG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (N03AG01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[421]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66317
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01DB09)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[422]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66359
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EX04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[423]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66400
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XK05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[424]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66443
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EC01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[425]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66485
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX52' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX52)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[426]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66528
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX29' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EX29)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[427]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66570
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01CA01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[428]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66612
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01CA02)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[429]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66652
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01CA03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[430]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66693
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01CA05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[431]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66735
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01CA04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[432]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66777
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XJ01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XJ01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[433]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66820
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L04AD03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[434]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66863
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XM04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XM04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[435]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66905
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XH01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XH01)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[436]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66944
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L02BG05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[437]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66985
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX53' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01XX53)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[438]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67029
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EL03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EL03)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[439]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67073
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX31' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01FX31)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[440]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67118
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (M05BA08)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[441]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67161
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EH04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01EH04)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[442]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67202
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE_VER"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc version 2026 (L01DB05)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-2026: ValueSet.compose.include[0].concept[443]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-systemische-therapie-substanzen-unii",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-systemische-therapie-substanzen-unii",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 442
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16937
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17098
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'F333OQQ9UV' is not valid in the system http://fdasis.nlm.nih.gov (error: [d036c386-b6a8-4d4c-bc74-90df85ed967c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17145
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '31M3WLJ3KG' is not valid in the system http://fdasis.nlm.nih.gov (error: [43aa87a0-5b1f-4db4-8961-ff64477d8de1]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17191
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '0ICW2LX8AS' is not valid in the system http://fdasis.nlm.nih.gov (error: [64831cfb-8b3c-460a-875b-632ffe41c851]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17236
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '0ZM2Z182GD' is not valid in the system http://fdasis.nlm.nih.gov (error: [a8d1b6aa-1418-432c-bd72-64d29958d80c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17283
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '85RE35306Z' is not valid in the system http://fdasis.nlm.nih.gov (error: [928f2f57-0d81-4c54-8036-78909c9f60bd]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17329
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '4EDF46E4GI' is not valid in the system http://fdasis.nlm.nih.gov (error: [b7e688b6-9ec2-4a9d-9070-d9317c3726a6]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17377
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '923X28214S' is not valid in the system http://fdasis.nlm.nih.gov (error: [08175846-816f-4ff1-bbe9-46d9fc48f6b2]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17422
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LQF7I567TQ' is not valid in the system http://fdasis.nlm.nih.gov (error: [2436d55f-87ec-4678-9b79-6e0b91701701]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[8]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17469
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N9B0H171MJ' is not valid in the system http://fdasis.nlm.nih.gov (error: [40d995f4-4526-473f-9fd3-0f0dc06fab47]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[9]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17520
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'SJ82PK3HWA' is not valid in the system http://fdasis.nlm.nih.gov (error: [4905c5a7-4c6c-4c2f-b140-8e007894c247]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[10]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17565
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'SMA5ZS5B22' is not valid in the system http://fdasis.nlm.nih.gov (error: [809cc4a8-d3d4-401e-8365-b8a728d1b294]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[11]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17613
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '6I3O3W6O3B' is not valid in the system http://fdasis.nlm.nih.gov (error: [247f8046-5a00-466b-af07-0b173532ea37]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[12]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17659
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'UC96G28EQF' is not valid in the system http://fdasis.nlm.nih.gov (error: [d81cd14b-ef25-49a8-b18d-81e8a080638e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[13]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17704
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '2E8412Y946' is not valid in the system http://fdasis.nlm.nih.gov (error: [e93f0553-e21c-444a-b853-40554b0b6e57]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[14]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17750
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'QSQ883V35U' is not valid in the system http://fdasis.nlm.nih.gov (error: [4f997e76-8690-4ba1-873e-09f6c6be0fae]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[15]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17795
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'F60NE4XB53' is not valid in the system http://fdasis.nlm.nih.gov (error: [71f29153-172a-4b71-9837-49cd2ba7525d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[16]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17840
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L4C1UY2NYH' is not valid in the system http://fdasis.nlm.nih.gov (error: [0e951caf-798c-40e4-96ba-d4f19c70bc63]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[17]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17884
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'PP449XA4BH' is not valid in the system http://fdasis.nlm.nih.gov (error: [5dbc337e-bbb3-4fe2-a6e4-8c00699ea363]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[18]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17928
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '703P9YDP7F' is not valid in the system http://fdasis.nlm.nih.gov (error: [1c6ce6e5-6cb1-453d-9aaf-243951c732a2]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[19]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 17973
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '5OGS5K699E' is not valid in the system http://fdasis.nlm.nih.gov (error: [f8062753-6d0e-48c5-8010-c99940afc41e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[20]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18019
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '6O01GMS00P' is not valid in the system http://fdasis.nlm.nih.gov (error: [7d317e0c-b3e6-4c22-bd3a-f66452b1c048]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[21]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18065
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '15JL80DG6H' is not valid in the system http://fdasis.nlm.nih.gov (error: [d23d6a86-d042-4659-857a-25e9e7579b82]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[22]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18110
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'KE7K32EME8' is not valid in the system http://fdasis.nlm.nih.gov (error: [4cd1cb07-53a3-41e3-abaf-e64434ffdb87]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[23]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18158
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'JTZ51LIXN4' is not valid in the system http://fdasis.nlm.nih.gov (error: [d7d24ec6-a6bc-49b0-ad5b-1ce1be24d514]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[24]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18208
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'MTM792B442' is not valid in the system http://fdasis.nlm.nih.gov (error: [74f9a2df-9332-4895-802c-34826358f189]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[25]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18255
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'S3AZD8D215' is not valid in the system http://fdasis.nlm.nih.gov (error: [9e89e164-b6d2-4a3e-a342-465f5af206ef]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[26]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18303
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'JNA39I7ZVB' is not valid in the system http://fdasis.nlm.nih.gov (error: [af4a1a11-5278-442a-a175-a1fb4595c04d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[27]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18351
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '08O3FQ4UNP' is not valid in the system http://fdasis.nlm.nih.gov (error: [9aaa9183-69ae-4b31-b86c-d1732352f326]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[28]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18396
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '15KFN616FK' is not valid in the system http://fdasis.nlm.nih.gov (error: [b1555259-7e18-4ae5-9465-9a173d17212c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[29]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18441
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '67DOW7F9GL' is not valid in the system http://fdasis.nlm.nih.gov (error: [9a5abd58-e75f-482e-8ef7-26411018725f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[30]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18486
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '0282IF4JC8' is not valid in the system http://fdasis.nlm.nih.gov (error: [555eec3b-1457-4b77-b8f2-0c1bdf104807]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[31]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18533
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G287IC9MH3' is not valid in the system http://fdasis.nlm.nih.gov (error: [a976cd93-fec8-498c-9d3b-8237f627e5aa]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[32]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18578
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'MAT637500A' is not valid in the system http://fdasis.nlm.nih.gov (error: [e7c2a721-c76a-4ed2-a21c-940d9cd568e6]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[33]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18625
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LXG44NDL2T' is not valid in the system http://fdasis.nlm.nih.gov (error: [9d2ddb80-4e4a-4fcd-823a-703f9c5780a7]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[34]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18670
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'PJ4H73IL17' is not valid in the system http://fdasis.nlm.nih.gov (error: [459982f5-0cd7-43ec-847a-3629a04e62aa]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[35]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18716
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'ZN90E4027M' is not valid in the system http://fdasis.nlm.nih.gov (error: [08e723bf-ec4f-4bcc-b2c3-5ebc113711a6]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[36]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18761
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'X8Y5U6NC7E' is not valid in the system http://fdasis.nlm.nih.gov (error: [433a9033-2e46-4c64-a877-2e9c3fd60d91]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[37]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18806
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'U36PGF65JH' is not valid in the system http://fdasis.nlm.nih.gov (error: [3048ebc6-7879-4d8d-88d6-a1340f272ef8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[38]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18851
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '6EM57086EA' is not valid in the system http://fdasis.nlm.nih.gov (error: [bab8d767-6b49-4804-9593-de2262ac58ad]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[39]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18897
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H4GXR80IZE' is not valid in the system http://fdasis.nlm.nih.gov (error: [8e597d66-f76b-449c-bb92-6879e3c34a63]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[40]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18942
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '7OSV6M6T4D' is not valid in the system http://fdasis.nlm.nih.gov (error: [418d957f-0a5a-48ee-ad84-e7570a806068]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[41]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18987
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '6HP0354G04' is not valid in the system http://fdasis.nlm.nih.gov (error: [6335ed78-56d0-410d-ae4c-a0165784de03]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[42]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19035
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'PRC974M49B' is not valid in the system http://fdasis.nlm.nih.gov (error: [e38908f8-3146-4ab9-98c6-4ab867af543f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[43]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19081
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'Q16CT95N25' is not valid in the system http://fdasis.nlm.nih.gov (error: [2536809c-1c95-4d71-b3ad-1f4bae1cba01]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[44]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19129
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'RJW23BQ0KW' is not valid in the system http://fdasis.nlm.nih.gov (error: [14fa84d8-f97e-456e-b091-940f0fd15446]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[45]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19174
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'LYK98WP91F' is not valid in the system http://fdasis.nlm.nih.gov (error: [3e4b40f8-ac5b-44c5-9e6e-8ab71d5a8011]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[46]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19220
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'RR5U4UFJ8L' is not valid in the system http://fdasis.nlm.nih.gov (error: [2a5becb7-d879-48c3-8575-731e612db451]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[47]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19264
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '2OQ3OPV2F8' is not valid in the system http://fdasis.nlm.nih.gov (error: [0dc2f037-4cb3-4585-87d9-eb067b0e73ca]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[48]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19321
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'GD2OWY1DTK' is not valid in the system http://fdasis.nlm.nih.gov (error: [16122353-1bf3-4fdc-9288-cf760c4c7273]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[49]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19369
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'W984C353CG' is not valid in the system http://fdasis.nlm.nih.gov (error: [26c5e3b8-e71a-4690-9962-4f0265833d84]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[50]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19421
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'RB3U3A1S27' is not valid in the system http://fdasis.nlm.nih.gov (error: [7635cc05-4f93-4132-a895-831d52099882]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[51]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19467
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L0HR9A577V' is not valid in the system http://fdasis.nlm.nih.gov (error: [db710742-22ef-420e-9ad6-03c915f98f45]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[52]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19513
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'DGK38A42AE' is not valid in the system http://fdasis.nlm.nih.gov (error: [997b2f96-127f-4054-ac30-72429235d6a5]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[53]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19559
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'VE267FC2UB' is not valid in the system http://fdasis.nlm.nih.gov (error: [11f8ad88-9bc8-4999-be95-49d836721214]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[54]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19603
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'S9OX9692ZB' is not valid in the system http://fdasis.nlm.nih.gov (error: [eace0cc5-7975-4c94-984d-475e8f41337e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[55]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19651
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '85V55ZLV2Z' is not valid in the system http://fdasis.nlm.nih.gov (error: [c11b4dd4-512e-4e45-bfa3-0bd29f47df27]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[56]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19698
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              {
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                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '4B57CWT710' is not valid in the system http://fdasis.nlm.nih.gov (error: [26f3889b-8aa9-4dda-ad68-695dc92e96e8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[57]"
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                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
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            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '28P3DU6DB3' is not valid in the system http://fdasis.nlm.nih.gov (error: [f7e19582-4b2b-41b2-914d-246d8c2eeaf5]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[58]"
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              {
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                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
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            "code": "business-rule",
            "details": {
              "text": "The code '539B57DFJF' is not valid in the system http://fdasis.nlm.nih.gov (error: [69a81d87-7780-4265-b061-60d761ad3675]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[59]"
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                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
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              "text": "The code '06P3KLK2J8' is not valid in the system http://fdasis.nlm.nih.gov (error: [5b9aa704-b805-4517-8afd-fc6f7dd25de6]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[60]"
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                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
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              "text": "The code '8V66F27X44' is not valid in the system http://fdasis.nlm.nih.gov (error: [bf8bb304-bb71-47a4-ad38-de53602a979b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[61]"
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              {
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                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
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              "text": "The code 'XGL4M23834' is not valid in the system http://fdasis.nlm.nih.gov (error: [89502eb8-57ff-44f3-bdac-490720cce4ff]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
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              {
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              {
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                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
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            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[63]"
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              {
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              {
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                "valueString": "InstanceValidator"
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                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
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              "text": "The code '0H2XLR2IKW' is not valid in the system http://fdasis.nlm.nih.gov (error: [851cbb5d-dfcf-4183-ae2b-d01ba369739c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[64]"
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          {
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
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              "text": "The code 'NYM5HO7I39' is not valid in the system http://fdasis.nlm.nih.gov (error: [c46413ca-34c2-4934-8312-fe5bc15a37f9]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[65]"
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                "valueString": "InstanceValidator"
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                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
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              "text": "The code '7K5O7P6QIU' is not valid in the system http://fdasis.nlm.nih.gov (error: [4581389d-2241-4d4b-9f3b-dffefced38b6]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[66]"
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                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
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            },
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              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[67]"
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                "valueString": "InstanceValidator"
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                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
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              "text": "The code '98DE7VN88D' is not valid in the system http://fdasis.nlm.nih.gov (error: [da669c9d-898f-42be-b87f-812c4b0f2f50]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[68]"
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              {
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                "valueString": "InstanceValidator"
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                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
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            },
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                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
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            },
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              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[70]"
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                "valueString": "InstanceValidator"
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              {
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                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
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            },
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              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[71]"
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              {
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                "valueString": "InstanceValidator"
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                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
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              "text": "The code '6HXC0O6JMV' is not valid in the system http://fdasis.nlm.nih.gov (error: [bb61c618-bd0b-40f0-a1d7-526b4cb1bad8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
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              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[72]"
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              {
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              {
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                "valueString": "InstanceValidator"
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                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
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              "text": "The code 'S9J80L3D1U' is not valid in the system http://fdasis.nlm.nih.gov (error: [bba76050-e304-448a-876e-762563beef48]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
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              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[73]"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
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            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'IBS1BZ4E4I' is not valid in the system http://fdasis.nlm.nih.gov (error: [28578d3a-4334-48a4-90c7-b9577c377a62]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[74]"
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              {
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                "valueInteger": 20569
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
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                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
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            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '4XG66BMN0D' is not valid in the system http://fdasis.nlm.nih.gov (error: [35a78383-1701-42a7-b2dc-0a32c42fc9be]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[75]"
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          {
            "extension": [
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                "valueInteger": 1
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              {
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                "valueInteger": 20614
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
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                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
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            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'AF75XOF6W3' is not valid in the system http://fdasis.nlm.nih.gov (error: [0279bf59-aeb8-43d4-b2fb-de13ccc9e08f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[76]"
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          {
            "extension": [
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                "valueInteger": 1
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20660
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
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            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '51WEW898IJ' is not valid in the system http://fdasis.nlm.nih.gov (error: [a330bcff-d5c7-4b3a-b42a-b868738fd556]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[77]"
            ]
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          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
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            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'P256HB60FF' is not valid in the system http://fdasis.nlm.nih.gov (error: [eac1204c-b009-4714-927e-c94c5b2666c0]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[78]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20765
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1N3L70MDFX' is not valid in the system http://fdasis.nlm.nih.gov (error: [1f6248e7-0023-4c45-91ee-d2bd1e61e518]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[79]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20810
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8FU7FQ8UPK' is not valid in the system http://fdasis.nlm.nih.gov (error: [1fb2df4b-8be9-4253-858c-cb4dd1847035]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[80]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20858
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'QOG25L6Z8Z' is not valid in the system http://fdasis.nlm.nih.gov (error: [832a9924-ad66-4f1c-9259-6b9de34b0e68]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[81]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20906
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'X8JR0I7JE1' is not valid in the system http://fdasis.nlm.nih.gov (error: [1d2f380b-1c40-41f7-baf9-1a8b3450882d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[82]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20952
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '6XG22YQM2Z' is not valid in the system http://fdasis.nlm.nih.gov (error: [8766672e-30f4-4e01-9f9d-751db0ad5f3a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[83]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21004
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'T41737F88A' is not valid in the system http://fdasis.nlm.nih.gov (error: [40469cd1-cee5-4232-aded-3665f580532c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[84]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21052
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '5P637IXG16' is not valid in the system http://fdasis.nlm.nih.gov (error: [72851bd6-a9bd-413e-87fb-2e71261cf698]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[85]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21098
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '8JXN261VVA' is not valid in the system http://fdasis.nlm.nih.gov (error: [b4659e44-12f5-4d06-a146-daf711b1bd37]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[86]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21141
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '230902QLLC' is not valid in the system http://fdasis.nlm.nih.gov (error: [c37a0ef6-e099-48ab-887e-90e738c557ea]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[87]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21188
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '5XO3JF0FEK' is not valid in the system http://fdasis.nlm.nih.gov (error: [1ecf7fb6-8e93-4aab-8e4a-db21f8a81ceb]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[88]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21243
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'IZY9ZSI6FI' is not valid in the system http://fdasis.nlm.nih.gov (error: [f05faa5b-caa9-4ef8-bd98-18840cdc55e4]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[89]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21298
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '94N635564T' is not valid in the system http://fdasis.nlm.nih.gov (error: [405f2ac8-6d42-4b58-9b8d-3ffb28afef7a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[90]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21342
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1Q8D39N37L' is not valid in the system http://fdasis.nlm.nih.gov (error: [f29d13d5-5b1e-46b9-91f5-cb569603df07]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[91]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21389
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'XT3Z54Z28A' is not valid in the system http://fdasis.nlm.nih.gov (error: [0b63738b-ebbe-4f84-8932-d1c24c47f59f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[92]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21434
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '04079A1RDZ' is not valid in the system http://fdasis.nlm.nih.gov (error: [d3642c48-6d2f-4096-b327-ce8520e4a35e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[93]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21489
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '5L84T2Z6NP' is not valid in the system http://fdasis.nlm.nih.gov (error: [98d34f42-bec5-4ea3-a11e-1afc6b567a5a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[94]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21537
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V1JK16Y2JP' is not valid in the system http://fdasis.nlm.nih.gov (error: [e44a46bb-5b8f-41c6-89ca-132a06cdeac4]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[95]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21585
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '2KT4YN1DP7' is not valid in the system http://fdasis.nlm.nih.gov (error: [cb1edf21-c058-4d0c-a118-9a6c5aa237f0]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[96]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21630
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'P88XT4IS4D' is not valid in the system http://fdasis.nlm.nih.gov (error: [c63a04f7-5bc4-4626-9e84-8b3ab9c94a3f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[97]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21678
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'Z8R4A37V9Q' is not valid in the system http://fdasis.nlm.nih.gov (error: [903fabe6-b034-4f57-87ae-03e0f98ec65a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[98]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21730
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'BNO1JG5MZC' is not valid in the system http://fdasis.nlm.nih.gov (error: [71e1f708-4859-438f-afdb-1230e6f6e1c0]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[99]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21782
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '4MXU9LJS4Q' is not valid in the system http://fdasis.nlm.nih.gov (error: [6dc6a5c0-9818-414d-b572-44d41023f3dd]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen-unii: ValueSet.compose.include[0].concept[100]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-systemische-therapie-substanzen",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-systemische-therapie-substanzen",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 437
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 54952
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55115
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA24' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [627eb116-d28a-4f31-b745-b0fb4f07f00c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55158
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE50' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [df4f21a4-2dd9-4464-9393-99e1c6474e75]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55201
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EF03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [1089bf6d-1658-4e35-9c6a-1f3770591ae6]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55241
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA22' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [8352fc65-fa9e-4707-ab35-41cb4a560964]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55283
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [d82ee343-2369-410d-a5a9-d5c23127388e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55328
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE51' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [7596a986-eb21-452a-ba3d-67f13e4ff9b1]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55373
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EL02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [b87d7fe3-29fa-4886-b4da-6458c243820e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55416
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [aa420605-7c67-4f4f-af92-25e5526905ca]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[8]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55457
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX77' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [6209396e-bec7-4f63-bf4c-2d4498eca50e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[9]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55499
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [5a3376dc-09b1-491f-baeb-588410a82a8f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[10]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55539
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [453c0177-f1e3-42e8-bf06-e8532aca5a56]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[11]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55579
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [b4eb5a89-935f-4f27-b4a4-a413e2f6afa7]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[12]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55621
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [4406eaea-eef4-40b0-82d2-ff981c5daa35]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[13]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55664
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX44' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [f2f55e02-6bd6-4372-bc5e-ce1397ebfa16]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[14]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55707
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [ecbd81fb-809e-4687-9ff0-c946a73e580e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[15]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55748
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE36' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [d639e0ee-04ef-4ab3-8e44-dfc90fef2df6]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[16]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55789
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [c6a173ef-3447-4f45-98f1-b1e42e86e900]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[17]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55830
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [c1df3727-765e-4e54-8f44-bfbf49d71b05]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[18]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55873
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA34' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [534814f7-d193-47a2-a394-f0a894d4f7ba]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[19]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55916
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AG06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [6d663505-8f24-4245-927f-51488903af1e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[20]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 55961
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [01e9b58a-8f0c-49e6-9367-f2a7b83a8261]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[21]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56005
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX22' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [3085dd47-99d0-42ab-a32f-1324dd14fac9]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[22]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56049
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XF02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [81b9e369-71cf-479c-9d6e-6733f52a75f2]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[23]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56090
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EM03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [6c703902-b451-4afc-bef5-68f51d9438d9]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[24]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56132
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [ce10cbee-7407-4ede-9a43-a88c2b16f949]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[25]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56172
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AM01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [7c9a72f7-100c-46c1-92cf-07f2db06dda0]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[26]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56220
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [71e664d4-9bb7-4097-9ce6-5e0634d3edf2]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[27]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56269
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [1d30f162-ea44-4130-8a9f-daa3f4987d99]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[28]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56312
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [ed655f25-ce2f-4083-8679-29d0aafd30fd]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[29]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56353
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [96096398-1dc1-40a4-b004-c6ba8ad2ce90]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[30]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56393
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [554a0df5-d35f-4d8f-afb0-0858b70fcf58]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[31]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56434
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX35' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [bdd4fcc4-b6b7-4524-b50c-fd779a44ff54]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[32]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56474
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [47a0ce1b-c675-4e4c-a34f-cfd0b39bb1ee]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[33]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56516
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [3db540bd-3891-48df-b777-db8ad12eab6d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[34]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56590
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [59134ef7-ed0a-4991-b5d7-35fc1ccd5ebf]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[35]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56632
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [cb502b68-c483-44ae-8144-b0bc60c3c41a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[36]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56676
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX27' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [06e3260e-1590-445e-bbac-d642e3d6fb32]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[37]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56717
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'P01BE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [dca3c19d-a54c-444e-92d6-d48dda61e713]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[38]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56758
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [e0f090f0-b4e8-4dd2-b941-6f9f7ac89772]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[39]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56802
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [2e300ae8-5d2d-49fe-ab89-090b59c55b0b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[40]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56846
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [386085d9-6638-4c39-b1f3-bc96ab7bb487]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[41]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56889
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [066da615-27c3-41d1-825f-5967be345c88]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[42]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56933
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [786d163e-ddb2-455a-a38b-e71fc51a4ec6]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[43]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 56973
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [61663f8d-e3ab-446c-b124-9a93cb82b2fc]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[44]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57027
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX70' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [5bbb7e84-0972-4441-93ba-262d763c76b7]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[45]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57081
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [8685bdc4-4db1-442d-b984-933bf2b8e129]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[46]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57121
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE17' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [0998fd66-ca60-4cde-ae90-1af2e5184674]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[47]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57161
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EK01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [1613bf2c-ca4c-40b4-8de6-d662c01fc469]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[48]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57203
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [faaa8bff-c2c8-47d6-8a5e-32990ec1909a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[49]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57246
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [8149e55c-5eb0-4df0-88fb-3a9dddea570f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[50]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57289
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [1ca09f3a-03f2-43e6-adf5-fa68eb3245ae]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[51]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57334
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [1fab81d6-9a9c-4d30-985d-d142ad673d4c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[52]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57386
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [2d718912-1a37-4f7c-847d-98a9c09ff0cb]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[53]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57428
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA28' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [6e2a91e0-e586-4d38-9032-c343cbb0bd12]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[54]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57469
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA26' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [850ed7ee-740b-41cc-9aac-c1d4b48a5937]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[55]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57510
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AG04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [d97bcf05-4f06-4732-a0d1-bfa4f5115b8e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[56]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57552
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX49' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [6a19dcc4-084a-4e94-babc-a3c55e012adb]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[57]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57594
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XH04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [217b7bfd-c105-4faa-abd7-bd9fa82e11af]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[58]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57636
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX74' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [37395169-ea9c-4e57-86ca-ffe1bd6fe2cb]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[59]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57679
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [b9c82d6b-1eae-4db1-8c1d-683b80980551]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[60]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57722
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [454f4aba-9552-42eb-a8b3-d610f1d4dbbb]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[61]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57763
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX25' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [b70d01af-f9d3-46b3-8a65-d20a12b06f6f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[62]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57804
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XF03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [2659a459-2397-470b-aea2-8c583e99325f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[63]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57847
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [3170b191-cbd5-4dda-a614-74e454d423a9]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[64]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57890
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE41' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [a0bb64c1-3155-4d6e-8076-bbf48757e1d3]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[65]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57933
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [85494af0-92f0-4330-8679-cb0927ee1fc0]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[66]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 57974
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [25425903-b954-41df-bf4f-b6a9c664a370]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[67]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58018
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [9e79a31c-6a00-4076-aaef-a58767a15fe8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[68]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58060
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX32' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [4771e776-c659-4565-bd03-2ce2a49bc6fd]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[69]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58102
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [9fea6509-6bab-453c-a131-35740ea985b4]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[70]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58143
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [e9e9d342-c5e4-4301-8a30-3c59717555aa]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[71]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58184
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [e9ba9291-6c30-4691-995d-609f581d27f4]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[72]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58235
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [cd5cffc0-3c7e-4719-ad00-a231d2af6b43]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[73]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58291
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [85b98fae-6934-40a4-914e-0eae2d448694]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[74]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58334
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [a20c506a-7529-48ff-9ca5-2e0ec835ee6b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[75]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58376
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE43' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [ae8b5b63-4327-4a8a-93fa-5f3f95dfa89c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[76]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58418
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [12a3a9ce-ba1c-443f-b959-224c4298b3ba]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[77]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58462
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N04BC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [b3001a8a-072d-4a13-bfbc-6411ce6c35db]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[78]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58503
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [ff123e1b-e5e9-47c9-b045-42027cb4bff7]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[79]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58543
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [ec44e5c7-e659-4030-bb35-024979ff0fe3]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[80]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58586
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [33a335eb-75b5-4f65-8527-4aec32760729]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[81]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58628
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N04BC06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [57d68d2b-ec9a-440c-b4c5-35ef36378f7b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[82]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58672
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE26' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [b0ef927c-d480-4bca-9d50-54a74ae516ff]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[83]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58716
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [185b1c4c-57b4-45e1-913d-bf48f41e75ac]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[84]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58766
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [16fb5490-5f0d-4890-ada2-72174b36cf76]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[85]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58812
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [ee8fbdad-326e-4f68-9a02-8bb0a5773ae0]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[86]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58855
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [571dbaa5-102c-4758-af18-c04000bf2f41]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[87]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58905
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX86' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [f1a9118e-3b50-4545-ada3-8b32ce6a409d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[88]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58948
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [b0ea57ec-bc6f-4179-9d6b-ca83d54be6c2]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[89]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 58992
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX27' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [2c8aac53-1dc5-492c-9c91-3d78b016c3e5]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[90]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59036
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [1d54b805-fbd3-435a-9489-19b607541e1e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[91]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59078
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX17' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [be8bef47-143e-4557-a893-fd38218af01b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[92]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59120
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EP01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [0a3d69c6-cd1f-4655-b981-61f612478a2c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[93]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59163
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [ed60262d-ae53-4bed-98cd-52bbfdf36db2]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[94]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59204
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [9b2e2bcf-1ee5-44f4-9aa7-10ee40ac6277]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[95]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59247
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX45' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [e6846c82-f68c-4d54-9926-5ba4ff20c648]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[96]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59290
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XG02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [db389ab6-4784-42f9-a77f-56932332d0f8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[97]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59330
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [56094c60-0ac0-48f2-bc0f-b976a8a1341c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[98]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59371
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [ef222df0-a300-4c21-95bb-f8336a6bdebf]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[99]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59414
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [cd637aca-08d6-418c-a33f-0b9856710205]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[100]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59456
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [6713cf07-cb69-43f6-830a-d199a9ae1852]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[101]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59497
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE28' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [9cecec28-787d-41f3-81af-0dd9f3ee647f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[102]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59538
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [da994c31-4c7d-44bc-9fc1-d88cabbaded4]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[103]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59588
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [771db034-b851-4d7a-a94e-7e2ad640e166]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[104]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59630
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [d0276bcb-e0aa-4da2-bc0d-0634f4dbb5d0]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[105]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59671
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [0c5bba37-59c7-42e2-9d2c-8942e06b98ea]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[106]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59715
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [c12ae8fb-497c-4711-993d-5019dcdcbb0f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[107]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59759
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03DB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [64a1d64d-6568-4827-a166-471a60b86cde]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[108]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59802
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [f796f60f-c797-4995-9960-b2792476ac37]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[109]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59845
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [6195b568-7b9c-42a8-b3e0-c7b0e42c7851]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[110]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59901
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [4939e9ad-3189-4ce6-9cd9-77dcba08cf34]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[111]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59942
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [39f00156-3b90-4c9d-a598-f814bb105538]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[112]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 59983
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [c2542b7e-5ba3-4ed0-bce8-57bdb289a4f1]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[113]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60027
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [e8e6b56f-75bb-48a9-ab8f-3d02e1d5b4b2]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[114]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60069
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [1276b094-d855-44fa-87bc-2a86138395a7]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[115]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60112
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE38' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [458f1f1b-2e45-44a9-99e8-49cec0ea7d41]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[116]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60155
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [8a6263fa-6309-4fc5-9dfa-b7c90547bc90]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[117]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60197
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX61' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [2e9594f0-f8e7-4f26-9f12-41edc8f469b3]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[118]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60239
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EM02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [b45acfd3-ab91-453b-8a5e-dea6ea0ca30b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[119]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60281
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE16' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [0e94e987-bdbc-4e07-b947-ae66bc697606]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[120]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60323
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [0c4f2f09-7202-4c1b-a1a5-15a97648859d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[121]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60370
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [3f3f9b17-808c-4018-85f4-10123b79add7]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[122]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60412
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03HA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [6a5291f2-ae85-4041-8869-4530f5fdc406]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[123]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60453
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [36f5fa65-07ea-46cc-bfaa-d6c94ffe2bcf]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[124]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60511
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XY01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [2fc2b8b1-4bcb-47dd-acc0-4b3dafb923a4]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[125]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60553
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE23' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [94491267-ed87-4087-ba90-af530f9fa1ba]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[126]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60595
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [201adff9-d119-41a3-96a0-ba497372f3b3]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[127]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60637
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [347b839b-3f83-47ff-9bbc-c0640eecf2b0]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[128]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60679
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [07333e1f-9f56-44e3-945a-109d5f298ea4]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[129]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60722
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [dc00b8e9-5ca6-4787-9d76-da1163ca520b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[130]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60766
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [501c48f6-b3d3-4d62-9a30-97fa2352db61]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[131]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60809
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [3881db4b-e804-459d-b2e3-f53e4fdeb88c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[132]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60857
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [a59481fb-fed2-48b8-9cc4-f93d55eba305]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[133]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60900
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [e04787d5-c616-4f7f-b5e1-d4f4adba7e87]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[134]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60941
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [eeb217bc-6f76-417e-bf3e-c589da393e05]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[135]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 60982
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [3ba65a7a-0059-444f-a716-a4499fa568a9]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[136]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61036
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX35' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [caadcafb-6170-4827-a0e2-29c7dad5fe28]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[137]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61080
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [a23d01b9-5b83-44e0-94d6-625647d19c5d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[138]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61121
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [f078f889-195b-4388-9f94-c1c47c815554]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[139]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61162
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [cdcacbe1-8f0e-4ec3-8435-39696bfa6f6b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[140]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61204
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [1e1317e4-7e7d-4450-9ac3-27f23fb274a2]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[141]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61254
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX29' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [f1f441ef-f9cc-41cf-8815-444c49738de6]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[142]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61295
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [09956006-85f2-47ea-85bc-e2665ff5e525]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[143]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61339
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [072582ea-2ba9-4dde-b81d-6c8134b5bd09]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[144]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61387
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [ec69d69a-7a56-4531-82ee-eea7426c2f5f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[145]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61428
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [cc2f23c0-16ed-40c8-b1c6-a33b7dd35da8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[146]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61471
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [f2900ac0-65b7-46b2-bfda-59c2dd90533b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[147]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61514
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [f742d6bb-48b1-4d3d-8772-fc24b551b8c0]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[148]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61556
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [01647710-b73e-4376-9d50-2287d09a306e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[149]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61598
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G04CB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [b8f67fee-1545-4e21-af0e-b07d1438c69f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[150]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61639
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EM04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [35af86be-cfab-42df-aa32-1b3cdd6e1419]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[151]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61681
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA25' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [972e19df-592a-4812-b4b8-f0957f783104]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[152]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61723
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AJ01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [b19a90e0-f8f2-4a55-bf01-f7d07d5e719f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[153]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61766
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [83207dc4-3672-45c7-8e7e-cfc65b7a5ec7]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[154]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61808
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA21' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [dc66fbea-cf00-4bc5-bdfe-f5a6842cd0b5]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[155]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61850
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AG02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [7baa8635-477f-4f47-8c97-66bc315a4286]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[156]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61893
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [17224c5f-e468-43cd-84f2-02258c9d9649]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[157]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61936
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [e6db1e9a-9b78-44c5-b0e8-8ec1c9c1715b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[158]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 61978
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [a681357b-e756-4e6f-8927-5c0d4ca909cb]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[159]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62021
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B02BX05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [2a224fb5-5597-4ca0-8e9b-ea268e68abf8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[160]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62063
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX59' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [5289c266-ba6f-4947-80b8-910fbc89d109]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[161]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62105
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XM01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [26dc5f3f-bd8c-4f5c-a729-3b73eeb6f0ce]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[162]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62148
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE46' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [f3cdd451-ba2c-4336-a718-43a41363d38d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[163]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62191
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [1b8c2ffc-2a08-471a-b9a1-1273ef930453]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[164]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62234
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [43ffe536-6408-46ae-b4c8-026f66d2ff37]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[165]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62284
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [3ddf6618-560f-46ef-b53f-2eaefd2136c8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[166]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62327
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [9df3c358-9509-4c37-b2c0-cbbe5036858b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[167]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62370
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [748829fd-6eb5-44c8-ac08-6c8df2f754a2]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[168]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62413
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX27' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [4906975a-a629-4900-80d5-0bde8872e80c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[169]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62455
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [00560313-b655-4d0f-9815-c31d32eb54c7]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[170]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62498
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EN01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [d2112b42-f45c-48c6-99fc-1d02e41acd46]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[171]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62538
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX41' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [2bd76e90-45b7-42ca-a85e-5514d839e56d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[172]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62591
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX36' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [95c04173-17ef-4365-919a-d63f73731e19]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[173]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62632
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [f9c01d1a-731b-495b-a130-88922c590ff6]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[174]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62673
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [581f6ae5-471a-4f70-987c-0e6e67a00cbd]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[175]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62719
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [5aa34cb6-3999-40e7-ad67-ce8ca77f8a76]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[176]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62762
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [65d2ed15-dbc2-416e-aaba-41ca01f7a587]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[177]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62804
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [f7125d32-5d13-44dc-8666-7cc85adbcd10]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[178]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62848
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [95b273d5-6904-4066-a35b-58feb3767c62]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[179]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62889
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [929f483e-f78f-4f08-8882-22ca92d8a515]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[180]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62929
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [116a52c6-b5a8-4ea5-987f-5ca53b03d91e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[181]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 62971
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [3d59080e-7610-46f4-8535-e35afe63e14b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[182]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63013
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EG02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [3b4fcae7-71be-4050-ae39-5fbb814f34f0]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[183]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63055
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AH02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [d2ee84c2-68da-4097-961e-b5c3cb199e1d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[184]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63096
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [39816832-2558-4e91-a5b8-b77ee6a67fd8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[185]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63138
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EJ02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [2a8bddf1-8609-4e95-b892-be5bef8c43a8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[186]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63180
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [07f5d8f9-b52c-452f-ba08-30788ec54e7d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[187]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63222
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G04CB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [edcef328-2a62-4939-9784-e19d1b2423a7]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[188]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63267
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB12' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [7eb15040-4e5d-4a92-b8d4-d971782ed419]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[189]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63309
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA27' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [de80729b-af9a-45a5-8dd2-1bb34342690e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[190]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63351
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [7c878aec-8796-4898-96c5-ff0cd4bb4d4d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[191]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63393
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [55d5dd47-3af2-4ef4-b12b-6835cbb51fb7]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[192]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63435
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [2709acb7-780c-4d63-b0f5-1ed5ad7fd021]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[193]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63479
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [d19ae7b5-8ee5-4373-a13e-45da53c4e040]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[194]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63538
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC52' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [f0599872-655f-4680-a77d-261e194258a9]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[195]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63578
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [d7bfe7bb-b746-4cb9-9994-353f53d5a9bc]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[196]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63624
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [7412540d-246f-458b-a6f9-abbbe4667ec8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[197]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63665
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [1361fa95-20ae-4810-9bac-6e59c561f5a0]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[198]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63707
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [95b9c75a-10ec-4e74-94a4-6a2d2526d4a6]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[199]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63751
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B02BX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [841e2206-f010-4ef1-9d8f-cb38262b769f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[200]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63793
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [868776c5-3acd-4e8b-bc81-5aaa8e646dcb]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[201]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63837
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EK04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [3bc57ba3-647c-49f3-857a-1670a0a552fb]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[202]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63880
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [13c01a97-36fd-4c11-bacf-dd00c8b5cd67]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[203]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63923
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EN04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [c6be3b3f-1773-4c9b-a2ff-4f42ab2b1225]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[204]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 63964
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [35836f64-154d-41f7-b49b-0be0f57d8fca]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[205]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64005
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [b77ef6c1-3dfe-4621-bf01-0153f2d01a38]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[206]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64047
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [751e44ed-9e9a-4f0f-bd9b-3c8cd5b201e0]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[207]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64100
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [ab589207-9c5c-4381-9cb0-31f9b6cefc83]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[208]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64142
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [2e093a34-9557-43c3-9843-22775d5e9fcf]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[209]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64186
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE54' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [563e13bf-78ba-424a-a794-4afc4f57cb82]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[210]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64230
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [c001d486-079a-46d1-960a-292b897a0d6b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[211]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64271
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX63' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [74c0e9ac-3cd6-41ab-a066-307e8016ded0]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[212]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64312
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XJ03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [2947752a-0887-484e-8630-ff53db44605f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[213]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64353
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [563ff1a8-9654-4127-9c29-af88ee65dc31]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[214]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64396
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [3aa1957c-dc10-48e1-9bd8-f36ee631a634]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[215]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64437
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [1d8b59e9-c8cb-4e8c-b006-52b1ead08345]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[216]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64479
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA19' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [81131723-b6ea-40ed-a70f-2421d2f874b3]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[217]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64533
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [840827e1-df5d-4da2-9164-50c29a035148]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[218]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64574
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [b7196bb3-8224-4e80-840f-e4c5f6fc0c0c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[219]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64621
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [effec25f-172c-41e0-b8fe-83cdb5ef431c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[220]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64666
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [6ce89314-d22c-44ad-9ba4-3c600350236d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[221]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64722
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V10XX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [8b8c62c9-191f-4f44-82e6-286915aef976]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[222]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64763
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE27' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [ce45fae3-fc3b-4aff-a395-83ef12d81530]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[223]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64804
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EL01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [e36b7891-2cd2-49e4-9a51-7c1c66fbbf99]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[224]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64846
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [76232ec9-638f-4378-94d5-bd693742b4ea]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[225]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64899
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [4be129cd-4142-4ebb-b73e-ce076e94b0a8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[226]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64941
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX47' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [070c212b-8610-489c-949f-b7794ffa9629]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[227]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 64983
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EM01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [b42d069b-e38e-4922-a41f-93b568c5c5eb]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[228]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65024
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [3c83ba23-ec8d-430c-98e0-817e3468fb7e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[229]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65064
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [ea5ab076-022b-44c0-96ca-df380118644a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[230]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65104
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [a8af1de8-fba5-4d98-ae6d-4332292d901a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[231]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65146
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX80' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [8fdf3a34-12e6-4c99-88dc-f4b7d1be05ab]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[232]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65187
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D06BB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [1dfaef88-69d7-43d9-8cce-a8f0d9a1436b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[233]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65229
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EM06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [dab1eb68-b2a2-43dd-852c-b25d768ab2bd]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[234]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65271
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [2133d76c-776d-4b3d-9f15-778f3426f5dc]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[235]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65317
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D06BX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [6aeb8b45-3337-4c45-a7a3-046aa90f4ff3]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[236]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65370
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [194c7f1c-8044-4707-914a-97d818bf5b4b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[237]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65428
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [60b39b27-3e46-4976-af15-a1f1f4bd1c3c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[238]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65478
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [f9959a4b-fc9a-4953-a60b-913960d29e74]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[239]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65528
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [e684c7f0-0410-497c-9b13-78d08fc919cc]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[240]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65579
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [8c9c51f0-cb02-4fc4-8425-18c39657fbfb]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[241]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65621
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [6fd3ebb8-85fb-402e-9872-6791be5e3477]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[242]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65663
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX19' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [ec7f6457-f2d0-475b-aa6a-d2d3cbf1e17f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[243]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65705
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CE02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [404d58d6-6330-4c8e-9f16-7e3e8bf4cdf0]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[244]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65747
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [1e57b8aa-ccd0-47f4-b35e-982b39259f10]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[245]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65789
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX62' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [9e0a8984-04bb-4959-ae91-0b2f5f00c933]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[246]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65831
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XM02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [dfe0ddbd-43b2-451c-8165-9f563a105204]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[247]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65873
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [4a23ada9-47d8-4026-9bc5-b99d94e4760e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[248]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65913
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX50' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [0052af0b-f87b-4d7e-9036-84eb98510ade]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[249]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65953
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XG03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [f8caae9a-a4b5-4f95-a9e2-2acdf9e7278c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[250]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 65996
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02CA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [9ba158ec-ff81-456e-aec5-dc125d2c4471]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[251]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66037
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [0548d77d-5413-4354-b71c-5c1e82f619cc]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[252]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66078
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [a3d4fae9-5d7a-4d1c-a55f-160468756acf]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[253]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66119
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EH01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [2a12a6cb-9fc6-4cbc-90e0-abdba47c03b2]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[254]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66164
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE53' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [8faa0dc0-b86c-4e3d-82ce-991b79f39910]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[255]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66209
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX12' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [7d0d491d-a866-4774-9d32-a76b4ceb4132]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[256]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66251
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [7fc0662f-5a1f-440a-abf3-ce15fc9a5232]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[257]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66293
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [9ad1d455-528e-4823-a928-92dd864b5aef]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[258]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66335
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AK01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [38e22d75-4723-41fd-873c-382057c99433]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[259]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66378
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [b249fe8d-e02d-4ac9-8bce-ea0f05b9c769]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[260]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66421
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [36f4fb0a-f9c5-461f-9b80-aea748739978]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[261]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66463
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE29' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [0fcea16b-8ca6-48cb-a797-09d6a14cb03a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[262]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66505
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [50df9f87-01ed-4b54-8bcb-d25699c4c7a5]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[263]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66545
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [168b4f77-3449-4122-9d3c-511cc66be5dc]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[264]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66588
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [38d7bd42-f9cb-4bc3-9a9c-e10e2174fe66]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[265]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66633
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX37' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [20d7fe00-078a-4b49-9a70-24de96f511cb]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[266]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66680
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [cbe65192-7350-4629-84de-ed88f400125c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[267]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66735
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [c841d302-eb0b-444e-8569-c9d3c2efe969]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[268]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66775
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [fc284b88-c75c-4b93-9106-0c363b90eec3]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[269]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66817
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'A16AX20' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [702277dc-72a7-44d0-8c81-74ffc9692321]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[270]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66858
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [257f2746-8fdd-4434-be80-34d8b9abe3a5]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[271]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66900
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE44' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [2c4b2ca4-d25f-422f-881c-7767df56c394]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[272]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66942
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01ED05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [4c243835-18a2-42cb-a4cc-169a4a8f6df6]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[273]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 66987
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX69' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [0a5d3270-3ffb-4d87-89be-5558dece5ae7]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[274]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67031
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [865a1bf8-05e0-4b85-ac9d-7f84ead3ffe6]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[275]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67074
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03DC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [82876bf1-7732-44e6-a934-1f57341db908]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[276]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67117
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [542fb9c5-bb92-4658-87e6-01f932b6bb7f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[277]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67158
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'J05AX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [c3682e8c-06f8-4ddc-966a-94af3715a103]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[278]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67202
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [e71f1bba-38ae-449d-8979-a09669b5bacc]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[279]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67244
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [0759cb35-6794-4664-aa26-4ac5a94de490]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[280]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67294
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [3c3c2dfc-3043-4cb0-9692-a3bc8b105ea5]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[281]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67335
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [23fa8a23-56cd-4f6b-b97a-c3bee7532ffa]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[282]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67376
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [bbaff6d6-0997-4052-a487-b9e14e68058b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[283]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67419
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'R03DX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [59616638-e55f-4448-86ce-966ab9d1fd18]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[284]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67464
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [a252c63d-ee58-41ab-b820-da912006dca7]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[285]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67501
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [548c77d9-bf39-4e5c-bd28-cc5aca702b7a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[286]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67541
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N07BC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [fb7a0c9b-17c9-4372-b776-da2c3b9b943b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[287]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67584
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [65564b2a-0f44-4114-843e-4bdf4820fd0c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[288]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67627
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [0e495b9a-9af8-45db-8cf2-0be1bf3ac238]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[289]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67697
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B03XA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [a631e3ad-d746-48ec-853f-3b384b6fbe6b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[290]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67749
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [8aca0d50-11d7-4c89-8fc6-c490dccd0818]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[291]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67798
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [164b508c-f7ea-4e8b-9422-4fb5ac77ea7b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[292]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67841
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE39' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [f81d7137-8d2c-443c-9046-cba5023057fa]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[293]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67884
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [8d3fe453-3efa-40b4-949c-b3c773942d53]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[294]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67928
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [90465d07-3e48-4a76-9851-02c930193a21]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[295]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 67970
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [e643534a-7126-432b-bc06-6075c677e920]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[296]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68012
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [9a8b93fc-9fc7-4a63-befb-ddbefa9546dd]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[297]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68055
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CH01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [0a78f6b0-2cf8-4836-b0d8-3a8cab164126]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[298]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68098
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CP01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [69bf8093-2629-4893-a8bd-0303c8077a67]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[299]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68142
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [bf1e8b73-f0f2-40e9-a36c-d30a07049cff]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[300]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68184
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX16' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [887e63f6-7fd4-4875-986a-bfd37dfa1da6]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[301]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68225
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [d87ddd55-b3dc-4fbc-9ed2-dbc35857d179]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[302]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68264
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX23' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [2a86e1e1-9c8f-4257-8bc5-03471f21c0cd]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[303]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68307
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [683d9c84-9f56-4170-becc-9ff9f355736a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[304]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68351
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [b0cbd86b-3745-4ca1-b503-e7a6c1810862]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[305]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68396
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [e8c71e21-6ab0-4bf9-a458-eb52e023b6bc]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[306]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68440
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [74eea6f4-5ea4-4115-bbdb-6dd73b225879]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[307]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68483
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX24' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [64bf13ae-c895-49c6-a1d1-7c4da374b4f3]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[308]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68528
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX25' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [860d82f5-7132-4d5a-bcbb-c25f13c9666f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[309]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68581
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [758e74fb-e548-420c-a106-364686ea3d04]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[310]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68626
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [637f51bb-1719-403d-8451-a352a6005925]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[311]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68671
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [af6a1a5b-200d-462d-90af-f949d4eadf38]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[312]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68718
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [d270584d-ea8a-4481-9811-97e5d36f2897]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[313]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68761
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA23' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [ba27f6da-f349-4588-9968-6647227ec46d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[314]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68804
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AG03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [f8b43ed2-ced1-46f0-a6ea-1b99aac1d30d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[315]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68854
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [544bb956-f10a-4374-870c-9f01e1cd6285]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[316]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68896
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX78' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [b8078cf7-25e0-4c51-bfe4-809b5c812b52]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[317]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68939
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FE03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [c3ab5099-3d53-4a5d-957b-d8b0c1bc4f35]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[318]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 68980
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [243fe568-9cba-4cb4-a3df-5909bd41b947]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[319]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69021
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE45' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [40375ee9-6df2-42ea-a1c9-714c4f53125e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[320]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69062
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EH02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [16036b69-421f-4cbf-a3a8-beb43381990e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[321]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69103
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [bf75e593-5b51-4f2a-9aff-608435be98e8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[322]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69144
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [4d6dda06-8041-459b-8787-0d217eb70783]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[323]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69185
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [d0603553-24ac-4d56-b7f9-8eae6c8c4ad8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[324]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69225
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [9197b6c1-7acd-4de1-880c-220a6a816ccd]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[325]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69269
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX81' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [cf242d55-ee0e-49b2-9880-a874b3ab16ef]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[326]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69311
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE31' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [d74efea8-2c16-4832-98b7-8011bb45cf1d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[327]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69353
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [03c9686a-22c7-4041-b28f-c844be78cfee]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[328]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69394
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX54' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [62082ec0-e9c1-443f-a96b-7f805ef0b4a8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[329]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69435
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [6bfcf22f-23e7-45a5-b9ec-065d2cfb07d2]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[330]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69476
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [b144e879-fc55-499c-83a5-aacc1bc879b0]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[331]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69532
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XY03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [b3b60c51-5900-46c3-a67f-ec7d2fb49b29]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[332]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69588
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FY02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [e5c3e9c4-41ed-4ee1-bccc-48f9b228a884]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[333]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69632
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [ac247c15-5c6c-4bf5-b787-ed478a6e2569]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[334]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69674
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX36' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [3c3634cb-be13-4415-af61-e88f45501701]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[335]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69728
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL12' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [4c78156a-0e2f-4123-8b39-8d291d6f20c0]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[336]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69769
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [8bcef48f-4389-4d19-8301-cd0042f26f8c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[337]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69813
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX34' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [1c305e82-3d62-4b5c-b371-d3e5ec91aa2f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[338]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69855
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [85acbc17-b428-4848-a5f4-87b4016b4afc]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[339]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69897
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AG12' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [2fb2fa72-fab6-463f-9a59-039f8e0a51a2]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[340]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69937
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX46' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [f9c0cbb5-0237-480d-b003-608841173b2f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[341]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 69977
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [be7d025f-7088-4217-a1fb-272778282995]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[342]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70019
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [6299cb20-fae9-4760-aa6e-6a7a36a693e3]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[343]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70073
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX40' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [3a646cc5-75d5-465c-987b-d093d9e633b4]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[344]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70124
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX16' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [c6929e7f-70a9-499f-bffe-613dd7012f83]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[345]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70166
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [bc9d14f4-060f-42db-bf8a-48ff6519f065]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[346]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70209
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE35' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [4989fb13-7b5b-4caf-8a40-ccf79317e940]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[347]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70252
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EB04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [bb328bca-ac89-4613-90e4-a96343cb5f50]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[348]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70295
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [49a3318e-d25c-4ef3-a7f3-a7a0fe4a37bc]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[349]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70337
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [04a6c247-6fd2-418e-ad70-0a7177e7cb1b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[350]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70389
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [2d27e9bc-88da-4ca6-a328-2b21e8f76780]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[351]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70431
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EJ03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [9210a019-7c40-4275-a736-085ce24ba3e9]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[352]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70474
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE33' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [b6818483-fcfb-4a99-b41d-aeadb1a9f98d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[353]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70517
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EF01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [66a7d198-be71-4744-aa30-ad83a18b4bcd]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[354]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70559
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AF08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [cafa43c6-4c0f-4097-a043-02258511fcca]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[355]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70604
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [6fb1fd5b-268d-416d-a5b4-ad9416faa0db]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[356]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70647
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FE02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [2e1d3bed-e77b-47fb-ac4f-e560d3f9e32d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[357]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70691
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX42' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [140133bc-5ee8-4b6b-a9ed-375c6e0a0f9e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[358]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70735
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XH03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [6f222563-ab94-4812-893d-6797bc4e04d1]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[359]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70776
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [c976f499-9779-4294-9eea-3f58d27b5824]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[360]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70820
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX24' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [7b14aa9a-b180-40da-b268-1b931b91b208]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[361]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70865
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AA13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [cac1fde9-f60f-4894-9783-8ef1dc02bd49]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[362]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70918
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [d8aa5f1a-6389-4f1d-b81b-16c08f9cfade]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[363]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 70971
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [86455c52-7757-4288-bf44-40bfec03426b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[364]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71016
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [74bb4291-437e-4657-939a-e6c12fc8c392]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[365]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71058
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [dec296c8-f4e1-479b-9538-42d67343cd0d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[366]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71101
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EN02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [3f2fb5ad-7c27-42f8-97f7-37cf2d4d93ea]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[367]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71143
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX84' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [ae480fea-2ba9-4242-a332-2726e2751b18]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[368]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71186
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [ab332ff4-3cfd-4c07-ad23-61b9b6d3f528]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[369]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71228
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [c56b3eab-c4e2-4c43-ac3d-97519d3d715b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[370]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71286
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XY02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [a4408e64-b5e1-41c5-951b-9b8a0bd37af3]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[371]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71344
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FY01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [943ef009-a88f-4144-8c48-edcbf2a862cc]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[372]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71386
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [22d4606b-e590-4792-a7be-5f64b6e91366]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[373]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71429
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [bb5a8b70-776c-40a8-aab0-0228f238e9db]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[374]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71470
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [ac3cfbfc-2fb1-41ab-8e1e-05ed4bee8d56]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[375]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71509
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V03AX10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [51478ae7-333f-4b3f-a6c0-afc82cfe54de]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[376]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71551
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX16' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [0d32d163-db69-4642-a94a-80e650d1cc0b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[377]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71593
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [59e48d0b-0479-43a0-8a54-56725fe56b69]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[378]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71644
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [52c80d58-0017-4217-9858-bc7a2f949c2d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[379]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71685
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [5fbedb11-81b6-46e0-bf58-610a1c2f63a3]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[380]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71738
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [372666b3-5588-4e71-bb26-b11514151f27]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[381]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71783
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [6811e41c-bdd9-436a-ab1b-a1f82c7903c2]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[382]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71826
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [f32b34a8-cf93-4b24-8d1a-074c406a4765]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[383]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71867
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE24' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [c93cbd79-fed2-43cb-845f-4c0a76e34bba]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[384]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71908
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [3ff8b3d3-8da7-407a-b9aa-2da1ee6fc517]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[385]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71956
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [ab3e6704-e92c-49cb-b87b-407b698a75af]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[386]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 71999
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [85a25066-6a90-4e62-b812-291da26c9217]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[387]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72042
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX23' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [360980a7-2051-40aa-8093-84b2d5da61c4]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[388]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72086
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D07AC18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [54267c48-211f-4f7c-a541-b6b13f004963]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[389]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72130
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [449c6806-c777-4d5e-b4ee-c3f6fcacdb27]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[390]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72173
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [9789cb31-5cde-43e7-915a-b82524ceee32]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[391]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72214
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H02AB07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [71f9a578-ca2c-4f1b-a8b6-dbb712218c96]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[392]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72257
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [c2e724db-208f-42b2-bd8c-66a2eb4a430b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[393]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72320
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D05AD' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [5512c17d-5f64-4e1a-93f4-2b7d128aac15]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[394]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72386
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'D05BA' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [c8ba483d-01d1-45ea-a41b-c2cbcb31fa85]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[395]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72429
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE52' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [ca349a14-2943-4196-953b-89c08ae707ec]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[396]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72472
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [bcb471d9-d853-4f25-b9ba-cdee88c1cfc8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[397]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72513
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'G03XC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [5e302cb8-8150-481b-90f8-2ad57f66797b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[398]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72556
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [eadc61d3-c5f1-4ea5-a9b2-12680ae87479]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[399]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72599
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FG02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [5b95e3e5-1b2a-4497-9b88-716c8de85af7]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[400]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72641
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [1a5c6555-9fb5-479f-bdc6-4b013b6ed66e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[401]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72684
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE21' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [3bf88e56-e3b8-4ce4-ac8b-b83254fd40de]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[402]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72727
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [206c9e66-a18b-4f7d-8e24-fc74edfdcdf8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[403]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72768
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [90003543-7656-40be-8d01-b38510f2afbc]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[404]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72812
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [0783398c-f4ba-4f5d-a6be-fe72c5215006]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[405]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72854
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE42' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [ddc22cca-fd66-4cb9-af6f-214b02ce63af]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[406]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72897
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EK05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [e6bd2b83-5f20-4044-b6e8-68ba165e546d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[407]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72939
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EF02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [ab47972f-48a8-4948-87b7-b77903a1458a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[408]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 72981
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [7a87cd66-32e9-4b79-b07d-a0e0240d199a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[409]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 73023
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX19' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [1f932cf9-9999-4626-8149-9322ce07d377]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[410]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 73068
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [e2af44fb-e18f-45a0-883b-24baa43450c3]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[411]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 73109
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [823e2c3e-ba1d-4491-a693-d8bfc9f417da]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[412]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 73151
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XH02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [8ca5b754-38a8-48e7-9619-30d8c081fbb4]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[413]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 73193
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX39' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [9d2d5942-6d1a-448c-a80d-1a3c344a0a01]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[414]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 73236
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'B02BX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [6f00ad17-ee2f-4a07-93e8-5a6ed3723255]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[415]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 73291
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AB15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [c39c5c24-3997-4efd-bb99-5b0a8fbe48a9]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[416]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 73332
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [87f3c94c-0c43-43a8-9b63-70a069477977]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[417]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 73375
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [114a7ef9-ced5-4ab4-98da-b071fa1827d9]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[418]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 73418
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EJ01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [6d9a57c5-130d-4450-b6f7-f277ee89c871]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[419]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 73461
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX19' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [0ba22097-79b7-44bc-9fda-12a0d9698ae1]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[420]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 73504
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EP03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [e59b68eb-737e-4b50-8514-90c3e68c89f9]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[421]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 73557
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX17' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [08ce1597-a9cf-4e0d-abba-e58384d64ae3]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[422]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 73600
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [b489f2e1-b918-4afb-add8-6d9157a9e3fe]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[423]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 73641
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX66' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [94fbef98-7815-4310-b7c5-59e01ab321f5]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[424]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 73686
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX22' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [91fe73a5-f458-48f6-91b1-17fbf8c8e76d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[425]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 73729
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [de566a45-5c27-4e00-883f-ca7770a4445f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[426]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 73769
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [64aa8cef-9b1c-4c85-98d1-0caa0fb05c0d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[427]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 73811
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [e0ed7b30-357c-4081-9982-59b75385bc9f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[428]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 73852
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AA10' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [e76e3fae-6fab-4c6c-b0e4-5edf24f197c3]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[429]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 73893
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AH01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [08c026fc-d4c6-4dd7-a545-ba5f030629e1]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[430]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 73946
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [2d711305-2d3a-4ff0-a445-b60517b1b4de]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[431]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 73990
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'H01CB01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [d27a68e4-1022-4b79-bfb0-af0b9f436ad6]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[432]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 74031
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XJ02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [dd923b82-0029-4fca-affb-8f277e50a143]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[433]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 74072
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [7b7923b5-a9d7-454f-a1ff-1d2a8ae4676b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[434]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 74113
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [e83ce333-c09d-4df0-a1ae-ff7ae6431fd9]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[435]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 74154
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX73' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [12808b2f-111d-4d5d-ae7d-004a978ab09c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[436]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 74198
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [6a054980-d7f2-4ad2-9bee-4940b5dc8160]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[437]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 74241
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [709ed32c-c9e7-470c-aa0a-43b93d9baa68]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[438]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 74282
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [4208ea3f-fb1f-46ff-bedf-cd3a8b1a9ed1]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[439]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 74323
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [7d46330b-cd04-40ed-8245-63c39448c328]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[440]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 74365
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AD02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [5f4b036a-024a-421e-9541-16208d508747]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[441]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 74408
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX12' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [009e39c4-ab02-49af-999e-1d7c8cbd673d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[442]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 74451
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX67' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [d20c527a-df3e-471c-9957-d71367339671]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[443]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 74494
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX60' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [da661aa3-6337-4e97-9ad5-3be9aac6ebd2]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[444]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 74537
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [2873c730-8685-4f53-9468-e3ac708869ac]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[445]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 74592
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX51' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [8a0848e8-571d-490e-8443-e4880571e8f3]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[446]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 74647
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [90de0a60-df45-47b4-851f-2078019720c0]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[447]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 74690
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX29' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [ac979e55-e008-4337-b4d4-2ac1e0e10ec4]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[448]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 74731
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [f245d541-7180-42be-934e-785b1ea7b9c3]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[449]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 74773
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L03AX11' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [c1290679-b4f3-4601-b2ba-2d04bba9ad0a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[450]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 74817
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX72' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [2c56b635-7854-4255-b808-8a2ac16628d2]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[451]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 74860
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX75' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [d1f11c5a-9542-476e-ba3d-a571b7708b4e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[452]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 74914
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC53' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [8e41a13e-108d-4f3e-a0ef-c31943b98714]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[453]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 74964
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC63' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [efb55b30-8154-4cd5-bcd8-5fbed0d571a1]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[454]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75027
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC73' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [49dc793e-e27a-4493-9541-5bd8e29212a5]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[455]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75069
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XD05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [2c0d66cc-f5db-4d83-b948-7a6597ffabc0]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[456]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75112
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AX03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [e8e77698-817e-4529-abf8-95126d548f7c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[457]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75156
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [a63a9543-e727-4e1f-a5c9-f88e87b3c5e1]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[458]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75200
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [e00d742e-b43d-4b7c-b626-a5f0aaf86291]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[459]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75241
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [c1257bbd-3a1d-40e7-97d5-55a01c56e569]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[460]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75282
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX21' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [b30967f3-f4a7-42f4-93c7-f2a0815a7849]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[461]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75323
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EP02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [ab79d8c7-cd18-4b0b-8b58-0fae9d6264b6]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[462]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75365
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AX02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [4c68ce7c-4b84-4391-815c-89fa79d146c8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[463]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75405
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [5c9c9d18-5263-41f4-b03e-29d74e96bfac]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[464]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75447
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX18' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [90d7c579-cf9f-4743-91df-f051a5817404]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[465]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75492
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [3a87f54c-cfe1-4a00-bbfc-16d39bd69f03]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[466]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75533
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BB03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [536e4e4d-861e-482d-86fe-60a6661e500d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[467]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75581
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX71' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [c34a0ca5-b274-427b-aa1a-9eab386a6e01]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[468]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75629
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XL04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [3f34aa33-d31c-4368-a671-0c21e2efdc02]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[469]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75673
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [5eeac4f2-e588-4859-97a6-c66f9b4862a4]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[470]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75714
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE34' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [42760d9d-fc0f-4b1e-a019-14a393513cae]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[471]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75755
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EK03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [70f9d944-ad2e-4ae4-89e4-2a3fcc32deb4]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[472]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75798
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AC07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [02439b94-fb58-4eff-9f70-7829b5e474d1]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[473]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75839
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX17' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [d52c12ae-da3c-4bcd-965e-9881f75c9d12]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[474]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75880
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [fd1ca486-6f5f-4fec-9af7-298656e93705]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[475]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75921
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [acd0f41f-61d9-4480-ac0e-53487dcfc145]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[476]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 75964
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FF13' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [58d5865b-0a11-4c54-8adf-7042a05a1fb8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[477]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 76007
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EC04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [78b86aae-4d55-4380-9865-3aa5bdfffac1]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[478]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 76071
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'V10XA53' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [ddfdd212-1080-4272-b3c9-1c6e9256a04c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[479]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 76114
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CX01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [4fe0cab6-3540-4af0-9915-83a23a656387]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[480]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 76156
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE25' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [ab4280d2-e849-4f8b-8403-25af5c1008dc]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[481]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 76198
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [5093c67b-e19f-49b5-849a-d74e1e0670f9]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[482]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 76241
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [ea4c30ea-2225-4b7f-b6af-bdf4d95ef43b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[483]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 76295
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [936fcb20-1128-4b55-8527-be2ca0620635]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[484]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 76350
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [b5ca8aba-53f4-40a9-ad46-1fa49f720f1b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[485]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 76402
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [e72583d6-524a-465a-b1c4-3256e9290fa4]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[486]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 76446
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX20' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [6d47486c-03e8-4761-9d47-07b3e040ff68]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[487]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 76488
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AB02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [c4eb26e4-d603-410c-8f3f-02db64276f4c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[488]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 76529
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX14' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [fc9d722e-5e03-4346-bee3-603258c27787]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[489]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 76570
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XF01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [67797c87-7360-4ef2-b177-41eab5e95ae8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[490]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 76612
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AC02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [230703fb-6e89-411b-b0fa-a4ef9eaa2d1e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[491]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 76670
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01BC59' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [4f38c774-6407-44c7-ae05-58e512f8de2f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[492]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 76713
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02AE04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [8739c956-e493-43b5-9c1f-9f80fd7b7125]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[493]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 76756
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AA07' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [eda302f0-bd93-4855-97f3-2da688654f60]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[494]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 76800
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EE06' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [be973473-cecb-45c2-8b8f-00c379123932]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[495]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 76841
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EH03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [534d7277-94c1-4e16-b773-c15ab0c9c874]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[496]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 76882
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01AD08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [81219311-551d-4127-b7bb-c6fc3119a7f6]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[497]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 76927
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'N03AG01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [9d47702e-8498-4a03-baf4-b75e2b73cda5]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[498]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 76969
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB09' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [2e6784c9-19ab-45b1-b5f7-8d1d1f7db5b2]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[499]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77011
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE12' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [12dddd1f-bf96-4f09-909f-1611cfde77f5]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[500]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77053
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [1528e344-c49e-4ca5-a32a-7870961ba049]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[501]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77094
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XK05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [7fd5ab77-0ea2-4cff-883e-60958b4f82d8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[502]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77137
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XE15' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [0763ce1f-6f4f-42a9-9d19-e492db0fee01]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[503]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77180
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EC01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [38c7cc72-9601-499a-a884-8c5f303e38b8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[504]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77222
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX52' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [9e4a6ea0-12e7-4a74-bfeb-8f45025d13c0]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[505]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77264
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [0dc5799a-a987-4d36-97d9-7870f6efa151]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[506]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77306
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA02' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [34414aee-465f-4707-ac7d-05e098b30d69]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[507]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77346
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [0b43c2f2-2141-4142-a5a6-542c57aff3dc]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[508]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77389
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EX29' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [6f979604-06c2-4374-832b-6e6cc54b9868]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[509]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77430
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [d41c2a90-3e37-41b6-b934-7b92709bde83]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[510]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77472
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01CA04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [56503b96-1b71-4e17-88da-71e0da9ecdb5]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[511]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77514
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XJ01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [e3ac79f1-cdfb-4c9d-8b7a-e66a38b9b1ef]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[512]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77556
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX43' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [3dfe4a0b-ef06-43c8-8f4d-6f4e7982790e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[513]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77599
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L04AD03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [cf177d4e-76f7-439a-8656-550c5933983f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[514]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77642
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XM04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [1975145b-39b8-465d-a954-02cab20c69dd]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[515]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77684
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX38' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [63486ad6-7a96-4025-935c-02b92f4dca6c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[516]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77726
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XH01' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [587ded54-50da-4d20-a9a5-c2328525f590]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[517]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77765
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L02BG05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [79c7d242-1f07-4287-8152-2ef20a7a284a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[518]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77806
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01XX53' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [96407c3f-e9af-4775-931e-569758f19b43]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[519]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77850
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EL03' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [1b1ab3e3-3c41-455a-b9b6-7cd09525a1af]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[520]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77893
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01EH04' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [74d57aab-ba86-4711-b2a9-9f742aa88ddd]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[521]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77937
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01FX31' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [d5e4b3f9-fc3d-4e24-b067-9ceafd330cee]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[522]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 77982
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'M05BA08' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [06fa36c2-02d2-4501-bce1-90794152f48f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[523]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 78023
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'L01DB05' is not valid in the system http://fhir.de/CodeSystem/bfarm/atc (error: [2eab025d-3658-42ff-bff2-4d9f5b744b69]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-systemische-therapie-substanzen: ValueSet.compose.include[0].concept[524]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-therapieabweichung",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-therapieabweichung",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 424
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-therapieabweichung: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6727
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-therapieabweichung: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-therapieempfehlung-typ",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-therapieempfehlung-typ",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 428
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-therapieempfehlung-typ: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6722
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-therapieempfehlung-typ: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-therapieplanung-typ",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-therapieplanung-typ",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 425
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-therapieplanung-typ: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6717
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-therapieplanung-typ: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-tnm-cp-praefix",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-tnm-cp-praefix",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 420
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-cp-praefix: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8045
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-cp-praefix: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-tnm-itc-suffix",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-tnm-itc-suffix",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 420
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-itc-suffix: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7746
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-itc-suffix: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-tnm-klassifikation-typ",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-tnm-klassifikation-typ",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 428
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-klassifikation-typ: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7636
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-klassifikation-typ: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8200
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '399537006' is not valid in the system http://snomed.info/sct (error: [c9563112-07ea-4bd7-8b83-6a5da74cb557]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-klassifikation-typ: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8263
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '399588009' is not valid in the system http://snomed.info/sct (error: [95211ae6-7031-4e58-8bff-2ca9d08fe5e6]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-klassifikation-typ: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8320
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '399703000' is not valid in the system http://snomed.info/sct (error: [09cff822-a8ab-4520-af2a-c2134edb57d7]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-klassifikation-typ: ValueSet.compose.include[0].concept[3]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-tnm-l-kategorie-werte",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-tnm-l-kategorie-werte",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 427
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-l-kategorie-werte: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7823
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-l-kategorie-werte: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-tnm-m-kategorie-werte-sct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-tnm-m-kategorie-werte-sct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 431
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-m-kategorie-werte-sct: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8977
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-m-kategorie-werte-sct: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-tnm-m-kategorie-werte",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-tnm-m-kategorie-werte",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 427
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-m-kategorie-werte: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8853
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-m-kategorie-werte: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-tnm-m-kategorie",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-tnm-m-kategorie",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 421
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-m-kategorie: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7392
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-m-kategorie: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7972
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '399387003' is not valid in the system http://snomed.info/sct (error: [53a502c9-2a10-47ee-a6ef-9c7569f4afcc]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-m-kategorie: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8037
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '371497001' is not valid in the system http://snomed.info/sct (error: [ae5479bd-66c3-4c4f-86a3-94fcecbabfcb]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-m-kategorie: ValueSet.compose.include[0].concept[2]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-tnm-m-symbol",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-tnm-m-symbol",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 418
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-m-symbol: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8885
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-m-symbol: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-tnm-n-kategorie-werte-sct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-tnm-n-kategorie-werte-sct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 431
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-n-kategorie-werte-sct: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10367
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-n-kategorie-werte-sct: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-tnm-n-kategorie-werte",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-tnm-n-kategorie-werte",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 427
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-n-kategorie-werte: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10171
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-n-kategorie-werte: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-tnm-n-kategorie",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-tnm-n-kategorie",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 421
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-n-kategorie: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7392
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-n-kategorie: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7972
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '399534004' is not valid in the system http://snomed.info/sct (error: [efbb95ce-72c1-4932-8f29-5dae20286449]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-n-kategorie: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8037
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '371494008' is not valid in the system http://snomed.info/sct (error: [a51b4454-ac72-43d0-8285-e7bb4f211aab]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-n-kategorie: ValueSet.compose.include[0].concept[2]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-tnm-pn-kategorie-werte",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-tnm-pn-kategorie-werte",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 428
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-pn-kategorie-werte: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7859
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-pn-kategorie-werte: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-tnm-s-kategorie-werte",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-tnm-s-kategorie-werte",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 427
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-s-kategorie-werte: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8355
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-s-kategorie-werte: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-tnm-sn-suffix",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-tnm-sn-suffix",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 419
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-sn-suffix: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7053
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-sn-suffix: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-tnm-t-kategorie-werte-sct",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-tnm-t-kategorie-werte-sct",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 431
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-t-kategorie-werte-sct: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 10367
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-t-kategorie-werte-sct: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-tnm-t-kategorie-werte",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-tnm-t-kategorie-werte",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 427
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-t-kategorie-werte: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 16677
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-t-kategorie-werte: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-tnm-t-kategorie",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-tnm-t-kategorie",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 421
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-t-kategorie: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7388
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-t-kategorie: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 7967
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '399504009' is not valid in the system http://snomed.info/sct (error: [a2b97fea-bd7f-4e30-805e-ec6ffa697737]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-t-kategorie: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8032
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '384625004' is not valid in the system http://snomed.info/sct (error: [e49c4d53-0c1e-478d-befd-e22ef75059b8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-t-kategorie: ValueSet.compose.include[0].concept[2]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-tnm-uicc-stadium",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-tnm-uicc-stadium",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 422
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-uicc-stadium: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 14189
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-uicc-stadium: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-tnm-v-kategorie-werte",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-tnm-v-kategorie-werte",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 427
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-v-kategorie-werte: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 8108
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-v-kategorie-werte: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-tnm-version",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-tnm-version",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 417
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-version: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6629
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tnm-version: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-tod",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-tod",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 409
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tod: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6483
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tod: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-tumormarker-loinc",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-tumormarker-loinc",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 423
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18692
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 18921
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1834-1' is not valid in the system http://loinc.org (error: [88473598-ce65-4435-9db8-4eff1840becb]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19001
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '24108-3' is not valid in the system http://loinc.org (error: [09e17834-e078-4c78-9243-9b9620cf505c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19080
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '10334-1' is not valid in the system http://loinc.org (error: [ec2893c9-e5d1-4315-be87-22ecd6b05d2d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19164
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '2857-1' is not valid in the system http://loinc.org (error: [c418becf-e25e-4cc7-8a6c-bb3bed21df61]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19248
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '19080-1' is not valid in the system http://loinc.org (error: [c70c7c7d-6c3f-4149-96f7-8257a4b5b10f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19345
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '21198-7' is not valid in the system http://loinc.org (error: [7f7a62de-5b2b-453c-9721-f5d4536181ff]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19423
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '9811-1' is not valid in the system http://loinc.org (error: [f2cee795-32dd-4f21-9f0c-a555703bccf3]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19496
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '20448-7' is not valid in the system http://loinc.org (error: [6257755e-3c61-447d-a838-9b4e50fc3b34]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[8]"
            ]
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          {
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19568
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
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                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '2338-2' is not valid in the system http://loinc.org (error: [21284c17-5f1a-4b78-95cc-ad670b92701d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[9]"
            ]
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          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19639
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '2333-3' is not valid in the system http://loinc.org (error: [d74105f2-d2d1-47c6-b71d-7e93c0468c9c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[10]"
            ]
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          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19732
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '3125-2' is not valid in the system http://loinc.org (error: [76329c4f-a9ad-407f-b18e-0828e2d95953]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[11]"
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          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19799
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
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                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '2961-1' is not valid in the system http://loinc.org (error: [6f1c6dcd-d9d1-4464-9e3b-f3f28773e480]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[12]"
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          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19869
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
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              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '18253-5' is not valid in the system http://loinc.org (error: [8d06125a-2034-43b5-aeaf-f0757af44289]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[13]"
            ]
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          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19933
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '27057-9' is not valid in the system http://loinc.org (error: [1661f91e-c267-4d59-ba82-887ace2643b3]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[14]"
            ]
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          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 19997
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '2940-5' is not valid in the system http://loinc.org (error: [5f0a0d34-e2a2-4a5c-89b7-cca57bfbbc33]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[15]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20060
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '2939-7' is not valid in the system http://loinc.org (error: [acd76e48-b2d8-4b49-aad5-5e9c215bb4eb]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[16]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20142
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1695-6' is not valid in the system http://loinc.org (error: [3471b079-e7be-4be6-bd53-cec604c2b072]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[17]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20227
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '31203-3' is not valid in the system http://loinc.org (error: [f4c6c3b8-b9af-439a-80e5-720872714a39]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[18]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20303
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1694-9' is not valid in the system http://loinc.org (error: [e84e3f6d-9a1f-4e84-a4ef-d8011af70956]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[19]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20398
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '44288-9' is not valid in the system http://loinc.org (error: [a21d96b0-080a-464f-9117-b4106580c0e1]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[20]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20466
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '2141-0' is not valid in the system http://loinc.org (error: [d12102a1-0270-4f3e-a080-14fab982784d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[21]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20540
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1992-7' is not valid in the system http://loinc.org (error: [bff2575d-325a-4865-8746-df1f16d0f604]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[22]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20613
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '2436-4' is not valid in the system http://loinc.org (error: [69731a17-75c0-46db-95b1-e8fe347b1db6]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[23]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20689
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '53595-5' is not valid in the system http://loinc.org (error: [a3402b56-b4e3-4a3d-a9f7-27da1f197ae5]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[24]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20775
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '13760-4' is not valid in the system http://loinc.org (error: [69e68c6c-7498-455d-82af-953183ecc7c0]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[25]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20853
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '11146-8' is not valid in the system http://loinc.org (error: [2a6e9dfa-b627-4d26-a2ef-dc13fa2e446a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[26]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 20930
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '3122-9' is not valid in the system http://loinc.org (error: [3779782e-2b96-4cd0-bdab-a16aecd61420]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[27]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21010
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '26706-2' is not valid in the system http://loinc.org (error: [e91aabfa-5e8a-4dd2-a39c-70c6b4f35b2b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[28]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21100
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '30571-4' is not valid in the system http://loinc.org (error: [86e35849-1923-4c63-b70a-7be12bedbe1d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[29]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21181
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '3124-5' is not valid in the system http://loinc.org (error: [64ccb6dc-e47b-444a-a1d5-2e333eecaae8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[30]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21261
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '27055-3' is not valid in the system http://loinc.org (error: [8b530040-b401-4af3-9b59-ac747249bdb1]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[31]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21335
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '2058-6' is not valid in the system http://loinc.org (error: [ea4f911e-f002-47b2-a245-84ba59edd11b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[32]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21404
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '2056-0' is not valid in the system http://loinc.org (error: [7d24684f-fd79-4028-bf53-6d8c0f6cc7ad]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[33]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21506
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '43108-0' is not valid in the system http://loinc.org (error: [2e2da92a-a655-4921-8630-8404ae91e3e8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[34]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21591
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '57462-4' is not valid in the system http://loinc.org (error: [e5e48134-a180-42e6-8b63-c4cc9d02bc8a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[35]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21670
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '2669-0' is not valid in the system http://loinc.org (error: [06729036-cd22-4435-80cc-7cb5472044e6]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[36]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21743
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '2609-6' is not valid in the system http://loinc.org (error: [39866734-7ab4-4844-918b-a87f6bde6224]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[37]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21818
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '2671-6' is not valid in the system http://loinc.org (error: [cbfff624-bbce-4047-9e67-000048774184]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[38]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21891
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '2842-3' is not valid in the system http://loinc.org (error: [de576436-aa98-4633-9918-920449a20e4e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[39]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 21967
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '2963-7' is not valid in the system http://loinc.org (error: [40e1bb08-b289-41cd-a5d0-8514e4007bbf]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[40]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 22044
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '15067-2' is not valid in the system http://loinc.org (error: [959d96eb-14a7-44dd-8007-38696d0de7d9]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[41]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 22118
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '10501-5' is not valid in the system http://loinc.org (error: [f7b3c6a2-8ed0-42ec-a9e7-4ba6787727ad]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[42]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 22194
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '3016-3' is not valid in the system http://loinc.org (error: [7b0541f1-a351-4df0-bec7-bba11aece402]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[43]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 22296
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '33358-3' is not valid in the system http://loinc.org (error: [d475baac-093b-4b88-ad2e-1ee1d7f3d921]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[44]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 22363
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '2465-3' is not valid in the system http://loinc.org (error: [e2db8c95-5a6c-4a7c-8152-2996981c9fc9]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[45]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 22430
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '2458-8' is not valid in the system http://loinc.org (error: [0a7c1075-bf6f-4ca2-b2f6-9245ed1534c4]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[46]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 22497
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '2472-9' is not valid in the system http://loinc.org (error: [9fb401ee-997a-487d-941e-b575e71b19de]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-tumormarker-loinc: ValueSet.compose.include[0].concept[47]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-verlauf-fernmetastasen",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-verlauf-fernmetastasen",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 428
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-verlauf-fernmetastasen: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6792
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-verlauf-fernmetastasen: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-verlauf-gesamtbeurteilung",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-verlauf-gesamtbeurteilung",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 431
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-verlauf-gesamtbeurteilung: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6821
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-verlauf-gesamtbeurteilung: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-verlauf-lymphknoten",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-verlauf-lymphknoten",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 425
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-verlauf-lymphknoten: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6747
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-verlauf-lymphknoten: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-verlauf-primaertumor",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-verlauf-primaertumor",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 426
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-verlauf-primaertumor: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 6761
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/StructureDefinition/shareablevalueset|4.0.2"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-verlauf-primaertumor: ValueSet.jurisdiction[0].coding[0].system"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-weitere-klassifikationen-auspraegungen",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-weitere-klassifikationen-auspraegungen",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 444
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen-auspraegungen: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 31510
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen-auspraegungen: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36319
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1290302009' is not valid in the system http://snomed.info/sct (error: [f4e3556a-f973-47fe-90a7-aafc7912d740]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen-auspraegungen: ValueSet.compose.include[21].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36448
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1290303004' is not valid in the system http://snomed.info/sct (error: [049d81db-50fe-4dc3-83c7-da5649771f0d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen-auspraegungen: ValueSet.compose.include[21].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 36577
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1290304005' is not valid in the system http://snomed.info/sct (error: [ae197b9b-4b1d-4e0f-b664-ddfb5da9903d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen-auspraegungen: ValueSet.compose.include[21].concept[3]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/ValueSet-mii-vs-onko-weitere-klassifikationen",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "ValueSet-mii-vs-onko-weitere-klassifikationen",
        "issue": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 430
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "Type_Specific_Checks_DT_URL_Resolve"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "invalid",
            "details": {
              "text": "No definition could be found for URL value 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko'"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.meta.extension[1].extension[2].value.ofType(uri)"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 22978
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "TerminologyEngine"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-context",
                "valueString": "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareablevalueset|2.0.0"
              }
            ],
            "severity": "warning",
            "code": "not-found",
            "details": {
              "text": "A definition for CodeSystem 'urn:iso:std:iso:3166:-2' could not be found, so the code cannot be validated"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.jurisdiction[0].coding[0].system"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 23574
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '444256004' is not valid in the system http://snomed.info/sct (Wrong Display Name 'American Joint Commission on Cancer, Cancer Staging Manual, 6th edition neoplasm staging system (tumor staging)' for http://snomed.info/sct#444256004. Valid display is 'American Joint Committee on Cancer, Cancer Staging Manual, 6th edition neoplasm staging system' (en) (for the language(s) 'en'))"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[0]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 23719
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '443830009' is not valid in the system http://snomed.info/sct (error: [3374f0ae-84f5-4082-8584-93dad1ed8a4c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 23845
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '897275008' is not valid in the system http://snomed.info/sct (error: [4ab12c01-09ef-485e-9001-6c151460c05b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 23945
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '254381008' is not valid in the system http://snomed.info/sct (error: [b83c4f2b-9c96-4787-a372-c35f0a75d643]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 24027
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '254373007' is not valid in the system http://snomed.info/sct (error: [9ff1297f-96d2-4007-a9b0-d129525f7fcb]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 24094
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '254372002' is not valid in the system http://snomed.info/sct (error: [ec4d79f1-bc90-4d10-8037-fcdc9a5ade2a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 24182
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '254374001' is not valid in the system http://snomed.info/sct (error: [edfeeece-edda-4d92-824e-bd87fa6a98f4]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 24244
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '254361007' is not valid in the system http://snomed.info/sct (error: [7bbd53f1-a2c6-4e4d-b524-3381829d50aa]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 24354
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1149164009' is not valid in the system http://snomed.info/sct (error: [1b4ca600-3906-4d31-b56e-309a37c2c520]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[8]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 24451
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1149099005' is not valid in the system http://snomed.info/sct (error: [dcd42136-1726-443d-bf29-1cadf66e3fbe]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[9]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 24536
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '385346008' is not valid in the system http://snomed.info/sct (error: [951c9421-feb4-4527-a2e3-79e61f0fa211]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[10]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 24619
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '385345007' is not valid in the system http://snomed.info/sct (error: [9d7fd506-34a8-4c82-a951-b289de1b616a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[11]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 24701
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '254375000' is not valid in the system http://snomed.info/sct (error: [4452fb04-e343-48dc-a361-90e9a0ce6ecf]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[12]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 24755
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '254360008' is not valid in the system http://snomed.info/sct (error: [f6f2f5d3-0c0d-479f-95f4-7fbeda2a9ce9]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[13]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 24840
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '254379006' is not valid in the system http://snomed.info/sct (error: [e1cd5d50-ff89-4bc3-bcaf-5af6ef97cdcc]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[14]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 24961
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '254386003' is not valid in the system http://snomed.info/sct (error: [73d3bc84-9c4c-4507-b39d-47e7805c0616]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[15]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 25029
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '106250008' is not valid in the system http://snomed.info/sct (error: [56f480f6-3cc8-4b36-a6d9-9935325bbe00]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[16]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 25100
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '106244003' is not valid in the system http://snomed.info/sct (error: [75c1a397-07d2-4f91-a0b7-665b3e2a3c24]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[17]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 25176
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '106247005' is not valid in the system http://snomed.info/sct (error: [540e0456-1021-411e-891c-443647d5b07b]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[18]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 25242
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '106245002' is not valid in the system http://snomed.info/sct (error: [a71eb223-4650-4a7a-bccc-8d9e7ce6d5d2]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[19]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 25307
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '106246001' is not valid in the system http://snomed.info/sct (error: [9d6660df-2ad3-4859-909c-689fe8d947be]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[20]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 25435
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '254383006' is not valid in the system http://snomed.info/sct (error: [ea549072-8641-4d5e-958d-5347eb16466a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[21]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 25561
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '254385004' is not valid in the system http://snomed.info/sct (error: [d025fba5-4abd-4192-afaa-f0e00b793160]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[22]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 25621
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '254384000' is not valid in the system http://snomed.info/sct (error: [f5157c1e-0622-430f-9716-a8c4ebe77515]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[23]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 25721
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1149162008' is not valid in the system http://snomed.info/sct (error: [4c6b5cc1-93b3-45e1-a8d1-1c4e62bb3b13]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[24]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 25834
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '254380009' is not valid in the system http://snomed.info/sct (error: [a889298c-bc48-4163-b180-691eeaa9d249]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[25]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 25905
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '254362000' is not valid in the system http://snomed.info/sct (error: [7418d6e2-781d-448f-81f8-266213ddc7e2]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[26]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 25984
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '385359000' is not valid in the system http://snomed.info/sct (error: [1d65bd26-acd2-4e66-a74e-4606ad9ecb3c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[27]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 26071
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1149131009' is not valid in the system http://snomed.info/sct (error: [7c626222-833e-4908-b1d4-8f83bbfa31f3]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[28]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 26179
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1149163003' is not valid in the system http://snomed.info/sct (error: [3e856ceb-6152-4f8a-ab0a-8d07111a621c]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[29]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 26255
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '254366002' is not valid in the system http://snomed.info/sct (error: [0470ef80-0034-498b-9ddf-02fb43fccb1e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[30]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 26328
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '254382001' is not valid in the system http://snomed.info/sct (error: [0b9bab31-b463-4b5e-899e-b951de55c27f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[31]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 26405
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '254378003' is not valid in the system http://snomed.info/sct (error: [a0053cb2-e6f5-426f-a06a-8bb526316c0f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[32]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 26513
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1287648008' is not valid in the system http://snomed.info/sct (error: [a25ff6a5-1732-43f5-a761-c49f60d1713e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[33]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 26608
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1287643004' is not valid in the system http://snomed.info/sct (error: [0aca3b51-9241-4d33-91f0-5ed5036177e0]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[34]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 26707
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '1287646007' is not valid in the system http://snomed.info/sct (error: [708ad428-d373-4cdc-abb7-522eb636a9b6]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[35]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 26790
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '716567001' is not valid in the system http://snomed.info/sct (error: [8c704fd1-125d-44c3-98e7-f5e774b98b6a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[36]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 26893
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '708736003' is not valid in the system http://snomed.info/sct (error: [d1f5172e-8727-472f-a078-8b4e98747a28]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[37]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 26997
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code '763236005' is not valid in the system http://snomed.info/sct (error: [52f056e6-d047-428e-94af-f86ad805f28a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[0].concept[38]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 27228
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'C186527' is not valid in the system http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl (error: [e88074de-dc6d-4f75-9089-b0aa33ed032a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[1].concept[1]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 27317
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'C141206' is not valid in the system http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl (error: [81169765-8bf2-4e85-9b2d-1f614c927091]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[1].concept[2]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 27369
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'C62575' is not valid in the system http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl (error: [7638db6f-a2b1-4da1-b44d-8fc9e4819cc5]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[1].concept[3]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 27422
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'C128932' is not valid in the system http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl (error: [cc50ebc0-0d43-4dc5-9b00-08665eb32d6a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[1].concept[4]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 27511
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'C186536' is not valid in the system http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl (error: [4ec9e960-f6d3-4484-bfbf-d2c6d7e197fd]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[1].concept[5]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 27566
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'C140258' is not valid in the system http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl (error: [c9116444-0835-4ff0-9ccc-ef7bdd4097be]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[1].concept[6]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 27617
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'C85407' is not valid in the system http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl (error: [251010ed-c8d4-4d20-96ca-a1c3380e0730]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[1].concept[7]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 27778
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'C99408' is not valid in the system http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl (error: [65b43814-a3b9-4255-8b75-2c6699eb6a73]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[1].concept[8]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 27848
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'C115132' is not valid in the system http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl (error: [15f60f13-ce76-4ac3-ade3-82a2caf3e280]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[1].concept[9]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 27933
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'C111073' is not valid in the system http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl (error: [b2dc63d4-e174-4b41-b596-81520cd7038a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[1].concept[10]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28020
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'C141168' is not valid in the system http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl (error: [547a383e-08bd-40c8-a481-4122a4b1a78e]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[1].concept[11]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28113
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'C141189' is not valid in the system http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl (error: [7d978b2d-72bc-460b-9e4e-bca406575afb]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[1].concept[12]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28210
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'C141178' is not valid in the system http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl (error: [f40abbad-db39-481e-8eb0-5ce7be8ea150]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[1].concept[13]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28307
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'C141158' is not valid in the system http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl (error: [03416e4f-d61d-4bfe-ac21-24506ad8f6d6]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[1].concept[14]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28369
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'C186520' is not valid in the system http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl (error: [fafa7165-e2e8-440e-b8e6-01ab2550f553]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[1].concept[15]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28450
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'C198826' is not valid in the system http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl (error: [35c66d18-6fdf-4611-9b3d-e7cbd417be6f]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[1].concept[16]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28568
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'C177308' is not valid in the system http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl (error: [a597e056-b9dc-47cb-acc9-d310ea5fe28d]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[1].concept[17]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28628
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'C186567' is not valid in the system http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl (error: [ecd1edcd-8936-4a74-abd1-cee8447b6013]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[1].concept[18]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28690
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'C123333' is not valid in the system http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl (error: [4a14fb79-7e57-42bb-998c-bddb1759a3b7]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[1].concept[19]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28790
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'C177309' is not valid in the system http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl (error: [16b79087-d9e7-4fe2-a4bd-1c7fdc1f558a]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[1].concept[20]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28851
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'C112006' is not valid in the system http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl (error: [1225f2a2-4906-4963-9baf-c9e57e492fc8]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[1].concept[21]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 28908
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'C18008' is not valid in the system http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl (error: [ca5b0e82-0f7b-4e8e-b39d-458944c04332]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[1].concept[22]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 29004
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'C141685' is not valid in the system http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl (error: [85f3bfe7-f149-4b4a-aa82-f2642f824095]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[1].concept[23]"
            ]
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-line",
                "valueInteger": 1
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-col",
                "valueInteger": 29065
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-issue-source",
                "valueString": "InstanceValidator"
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id",
                "valueCode": "VALUESET_INCLUDE_INVALID_CONCEPT_CODE"
              }
            ],
            "severity": "error",
            "code": "business-rule",
            "details": {
              "text": "The code 'C18214' is not valid in the system http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl (error: [04c867ec-7aea-41cc-b4cd-71a1b15151ae]: Type-level request to $validate-code must specify either valueSet or url parameter.)"
            },
            "expression": [
              "ValueSet/mii-vs-onko-weitere-klassifikationen: ValueSet.compose.include[1].concept[24]"
            ]
          }
        ]
      }
    },
    {
      "fullUrl": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/OperationOutcome/Parameters-mii-param-onko-manifest",
      "resource": {
        "resourceType": "OperationOutcome",
        "id": "Parameters-mii-param-onko-manifest"
      }
    }
  ]
}